YOUNG BREAST-CANCER PATIENTS HAVE UNFAVORABLE PROGNOSIS BECAUSE OF BIOLOGICALLY AGGRESSIVE TUMORS

  • Authors:
    • S AALTOMAA
    • P LIPPONEN
    • S PAPINAHO
  • View Affiliations

  • Published online on: February 1, 1993     https://doi.org/10.3892/ijo.2.2.331
  • Pages: 331-334
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Abstract

A retrospective analysis of 418 breast cancer patients was done to investigate the differencies in survival, in clinical and in histopathological variables between the different age groups giving special attention to young women. Three age groups were used, young (age less-than-or-equal-to 40 years), middle-aged (41-50 years) and elderly women (>50 years). The tumours in young women had high mitotic activity (p<0.001), high S phase fraction (p=0.025), dense lymphocyte infiltration (p=0.027), high nuclear variable values (p=0.020-0.042), bilateral disease (p=0.001) and low estrogen receptor content (p=0.013) as compared with other age groups. The prognosis of patients under the age of 40 was more unfavorable than their middle-aged counterparts (p=0.0207). The young women have more rapidly proliferating breast tumours than the middle-aged or the elderly women, and moreover the tumours are often bilateral.

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February 1993
Volume 2 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
AALTOMAA S, LIPPONEN P and PAPINAHO S: YOUNG BREAST-CANCER PATIENTS HAVE UNFAVORABLE PROGNOSIS BECAUSE OF BIOLOGICALLY AGGRESSIVE TUMORS. Int J Oncol 2: 331-334, 1993
APA
AALTOMAA, S., LIPPONEN, P., & PAPINAHO, S. (1993). YOUNG BREAST-CANCER PATIENTS HAVE UNFAVORABLE PROGNOSIS BECAUSE OF BIOLOGICALLY AGGRESSIVE TUMORS. International Journal of Oncology, 2, 331-334. https://doi.org/10.3892/ijo.2.2.331
MLA
AALTOMAA, S., LIPPONEN, P., PAPINAHO, S."YOUNG BREAST-CANCER PATIENTS HAVE UNFAVORABLE PROGNOSIS BECAUSE OF BIOLOGICALLY AGGRESSIVE TUMORS". International Journal of Oncology 2.2 (1993): 331-334.
Chicago
AALTOMAA, S., LIPPONEN, P., PAPINAHO, S."YOUNG BREAST-CANCER PATIENTS HAVE UNFAVORABLE PROGNOSIS BECAUSE OF BIOLOGICALLY AGGRESSIVE TUMORS". International Journal of Oncology 2, no. 2 (1993): 331-334. https://doi.org/10.3892/ijo.2.2.331