Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review)

  • Authors:
    • Gelareh Zadeh
    • Abhijit Guha
  • View Affiliations

  • Published online on: September 1, 2003     https://doi.org/10.3892/ijo.23.3.557
  • Pages: 557-565
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Abstract

Angiogenesis involves a highly regulated and coordinated interaction of multiple angiogenic factors and is critical for both embryonal development and physiological vessel formation in adults. Angiogenesis is also proven to significantly contribute to the progression of various disease processes. Pathological angiogenesis is thought to recapitulate physiological angiogenesis, however the precise molecular mechanisms are not understood. Various angiogenic genes and gene products have been isolated, purified, and cloned from both neoplastic and normal tissues that contribute to the angiogenic process. In this review we summarize the role of the main angiogenic factors in both normal embryonal vascularization of the embryonal nervous system together with the main brain tumors seen in adults.

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September 2003
Volume 23 Issue 3

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Zadeh G and Zadeh G: Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review). Int J Oncol 23: 557-565, 2003
APA
Zadeh, G., & Zadeh, G. (2003). Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review). International Journal of Oncology, 23, 557-565. https://doi.org/10.3892/ijo.23.3.557
MLA
Zadeh, G., Guha, A."Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review)". International Journal of Oncology 23.3 (2003): 557-565.
Chicago
Zadeh, G., Guha, A."Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review)". International Journal of Oncology 23, no. 3 (2003): 557-565. https://doi.org/10.3892/ijo.23.3.557