Cryotreatment as a simple method for cell preparation in autologous tumor cell-based vaccination

  • Authors:
    • Mathieu Maltais
    • Alain R. Thierry
    • Sally O. Walshaw
    • Carole Lavigne
  • View Affiliations

  • Published online on: March 1, 2010     https://doi.org/10.3892/ijo_00000537
  • Pages: 617-622
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Abstract

Immunotherapies using autologous whole tumor cell vaccines have great potential in the treatment of cancer. Very few studies report the use of cryotreatment for the preparation of cells in cell-based vaccines. In this study, we demonstrated that a preparation containing cryotreated human breast cancer cells has the same capacity as a preparation containing irradiated human breast cancer cells to induce the activation of immune cells in vivo. The vaccine strategy proposed in this study may provide the experiment basis for the use of autologous or allogeneic breast cancer cells in the cell-based vaccine approach for the treatment of breast cancer and other types of cancer as well.

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March 2010
Volume 36 Issue 3

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Maltais M, Thierry AR, Walshaw SO and Lavigne C: Cryotreatment as a simple method for cell preparation in autologous tumor cell-based vaccination. Int J Oncol 36: 617-622, 2010
APA
Maltais, M., Thierry, A.R., Walshaw, S.O., & Lavigne, C. (2010). Cryotreatment as a simple method for cell preparation in autologous tumor cell-based vaccination. International Journal of Oncology, 36, 617-622. https://doi.org/10.3892/ijo_00000537
MLA
Maltais, M., Thierry, A. R., Walshaw, S. O., Lavigne, C."Cryotreatment as a simple method for cell preparation in autologous tumor cell-based vaccination". International Journal of Oncology 36.3 (2010): 617-622.
Chicago
Maltais, M., Thierry, A. R., Walshaw, S. O., Lavigne, C."Cryotreatment as a simple method for cell preparation in autologous tumor cell-based vaccination". International Journal of Oncology 36, no. 3 (2010): 617-622. https://doi.org/10.3892/ijo_00000537