1
|
Kitada T, Asakawa S, Hattori N, Matsumine
H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y and Shimizu N:
Mutations in the parkin gene cause autosomal recessive juvenile
parkin-sonism. Nature. 392:605–608. 1998. View Article : Google Scholar : PubMed/NCBI
|
2
|
La Cognata V, Iemmolo R, D'Agata V,
Scuderi S, Drago F, Zappia M and Cavallaro S: Increasing the coding
potential of genomes through alternative splicing: The case of
PARK2 gene. Curr Genomics. 15:203–216. 2014. View Article : Google Scholar : PubMed/NCBI
|
3
|
Walden H and Martinez-Torres RJ:
Regulation of Parkin E3 ubiquitin ligase activity. Cell Mol Life
Sci. 69:3053–3067. 2012. View Article : Google Scholar : PubMed/NCBI
|
4
|
Hristova VA, Beasley SA, Rylett RJ and
Shaw GS: Identification of a novel Zn2+-binding domain
in the autosomal recessive juvenile Parkinson-related E3 ligase
parkin. J Biol Chem. 284:14978–14986. 2009. View Article : Google Scholar : PubMed/NCBI
|
5
|
Shimura H, Hattori N, Kubo S, Mizuno Y,
Asakawa S, Minoshima S, Shimizu N, Iwai K, Chiba T, Tanaka K, et
al: Familial Parkinson disease gene product, parkin, is a
ubiquitin-protein ligase. Nat Genet. 25:302–305. 2000. View Article : Google Scholar : PubMed/NCBI
|
6
|
Ledesma MD, Galvan C, Hellias B, Dotti C
and Jensen PH: Astrocytic but not neuronal increased expression and
redistribution of parkin during unfolded protein stress. J
Neurochem. 83:1431–1440. 2002. View Article : Google Scholar : PubMed/NCBI
|
7
|
Kitada T, Asakawa S, Minoshima S, Mizuno Y
and Shimizu N: Molecular cloning, gene expression, and
identification of a splicing variant of the mouse parkin gene. Mamm
Genome. 11:417–421. 2000. View Article : Google Scholar : PubMed/NCBI
|
8
|
Solano SM, Miller DW, Augood SJ, Young AB
and Penney JB Jr: Expression of alpha-synuclein, parkin, and
ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes
associated with familial Parkinson's disease. Ann Neurol.
47:201–210. 2000. View Article : Google Scholar : PubMed/NCBI
|
9
|
Fett ME, Pilsl A, Paquet D, van Bebber F,
Haass C, Tatzelt J, Schmid B and Winklhofer KF: Parkin is
protective against proteotoxic stress in a transgenic zebrafish
model. PLoS One. 5:e117832010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Trempe JF and Fon EA: Structure and
function of Parkin, PINK1, and DJ-1, the three musketeers of
neuroprotection. Front Neurol. 4:382013. View Article : Google Scholar : PubMed/NCBI
|
11
|
Henn IH, Bouman L, Schlehe JS, Schlierf A,
Schramm JE, Wegener E, Nakaso K, Culmsee C, Berninger B, Krappmann
D, et al: Parkin mediates neuroprotection through activation of
IkappaB kinase/nuclear factor-kappaB signaling. J Neurosci.
27:1868–1878. 2007. View Article : Google Scholar : PubMed/NCBI
|
12
|
Winklhofer KF: Parkin and mitochondrial
quality control: Toward assembling the puzzle. Trends Cell Biol.
24:332–341. 2014. View Article : Google Scholar : PubMed/NCBI
|
13
|
da Costa CA, Sunyach C, Giaime E, West A,
Corti O, Brice A, Safe S, Abou-Sleiman PM, Wood NW, Takahashi H, et
al: Transcriptional repression of p53 by parkin and impairment by
mutations associated with autosomal recessive juvenile Parkinson's
disease. Nat Cell Biol. 11:1370–1375. 2009. View Article : Google Scholar : PubMed/NCBI
|
14
|
Sunico CR, Nakamura T, Rockenstein E,
Mante M, Adame A, Chan SF, Newmeyer TF, Masliah E, Nakanishi N and
Lipton SA: S-Nitrosylation of parkin as a novel regulator of
p53-mediated neuronal cell death in sporadic Parkinson's disease.
Mol Neurodegener. 8:292013. View Article : Google Scholar : PubMed/NCBI
|
15
|
Quinn N, Critchley P and Marsden CD: Young
onset Parkinson's disease. Mov Disord. 2:73–91. 1987. View Article : Google Scholar : PubMed/NCBI
|
16
|
Takahashi H, Ohama E, Suzuki S, Horikawa
Y, Ishikawa A, Morita T, Tsuji S and Ikuta F: Familial juvenile
parkinsonism: Clinical and pathologic study in a family. Neurology.
44:437–441. 1994. View Article : Google Scholar : PubMed/NCBI
|
17
|
Golbe LI: Young-onset Parkinson's disease:
A clinical review. Neurology. 41:168–173. 1991. View Article : Google Scholar : PubMed/NCBI
|
18
|
Cesari R, Martin ES, Calin GA, Pentimalli
F, Bichi R, McAdams H, Trapasso F, Drusco A, Shimizu M, Masciullo
V, et al: Parkin, a gene implicated in autosomal recessive juvenile
parkinsonism, is a candidate tumor suppressor gene on chromosome
6q25-q27. Proc Natl Acad Sci USA. 100:5956–5961. 2003. View Article : Google Scholar : PubMed/NCBI
|
19
|
Denison SR, Wang F, Becker NA, Schüle B,
Kock N, Phillips LA, Klein C and Smith DI: Alterations in the
common fragile site gene Parkin in ovarian and other cancers.
Oncogene. 22:8370–8378. 2003. View Article : Google Scholar : PubMed/NCBI
|
20
|
Picchio MC, Martin ES, Cesari R, Calin GA,
Yendamuri S, Kuroki T, Pentimalli F, Sarti M, Yoder K, Kaiser LR,
et al: Alterations of the tumor suppressor gene Parkin in non-small
cell lung cancer. Clin Cancer Res. 10:2720–2724. 2004. View Article : Google Scholar : PubMed/NCBI
|
21
|
Wang F, Denison S, Lai JP, Philips LA,
Montoya D, Kock N, Schüle B, Klein C, Shridhar V, Roberts LR, et
al: Parkin gene alterations in hepatocellular carcinoma. Genes
Chromosomes Cancer. 40:85–96. 2004. View Article : Google Scholar : PubMed/NCBI
|
22
|
Yeo CWS, Ng FSL, Chai C, Tan JM, Koh GR,
Chong YK, Koh LW, Foong CS, Sandanaraj E, Holbrook JD, et al:
Parkin pathway activation mitigates glioma cell proliferation and
predicts patient survival. Cancer Res. 72:2543–2553. 2012.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Ohgaki H and Kleihues P: The definition of
primary and secondary glioblastoma. Clin Cancer Res. 19:764–772.
2013. View Article : Google Scholar
|
24
|
Rong Y, Durden DL, Van Meir EG and Brat
DJ: ‘Pseudopalisading’ necrosis in glioblastoma: A familiar
morphologic feature that links vascular pathology, hypoxia, and
angiogenesis. J Neuropathol Exp Neurol. 65:529–539. 2006.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Svensson KJ, Kucharzewska P, Christianson
HC, Sköld S, Löfstedt T, Johansson MC, Mörgelin M, Bengzon J, Ruf W
and Belting M: Hypoxia triggers a proangiogenic pathway involving
cancer cell microvesicles and PAR-2-mediated heparin-binding EGF
signaling in endothelial cells. Proc Natl Acad Sci USA.
108:13147–13152. 2011. View Article : Google Scholar : PubMed/NCBI
|
26
|
Veeriah S, Taylor BS, Meng S, Fang F,
Yilmaz E, Vivanco I, Janakiraman M, Schultz N, Hanrahan AJ, Pao W,
et al: Somatic mutations of the Parkinson's disease-associated gene
PARK2 in glioblastoma and other human malignancies. Nat Genet.
42:77–82. 2010. View
Article : Google Scholar
|
27
|
Xu L, Lin DC, Yin D and Koeffler HP: An
emerging role of PARK2 in cancer. J Mol Med Berl. 92:31–42. 2014.
View Article : Google Scholar
|
28
|
Stamm S, Ben-Ari S, Rafalska I, Tang Y,
Zhang Z, Toiber D, Thanaraj TA and Soreq H: Function of alternative
splicing. Gene. 344:1–20. 2005. View Article : Google Scholar : PubMed/NCBI
|
29
|
Shin C and Manley JL: Cell signalling and
the control of pre-mRNA splicing. Nat Rev Mol Cell Biol. 5:727–738.
2004. View
Article : Google Scholar : PubMed/NCBI
|
30
|
Modrek B and Lee C: A genomic view of
alternative splicing. Nat Genet. 30:13–19. 2002. View Article : Google Scholar
|
31
|
Scuderi S, La Cognata V, Drago F,
Cavallaro S and D'Agata V: Alternative splicing generates different
parkin protein isoforms: Evidences in human, rat, and mouse brain.
BioMed Res Int. 2014:6907962014. View Article : Google Scholar : PubMed/NCBI
|
32
|
Sunada Y, Saito F, Matsumura K and Shimizu
T: Differential expression of the parkin gene in the human brain
and peripheral leukocytes. Neurosci Lett. 254:180–182. 1998.
View Article : Google Scholar
|
33
|
Dagata V and Cavallaro S: Parkin
transcript variants in rat and human brain. Neurochem Res.
29:1715–1724. 2004. View Article : Google Scholar : PubMed/NCBI
|
34
|
Beyer K, Domingo-Sàbat M, Humbert J,
Carrato C, Ferrer I and Ariza A: Differential expression of
alpha-synuclein, parkin, and synphilin-1 isoforms in Lewy body
disease. Neurogenetics. 9:163–172. 2008. View Article : Google Scholar : PubMed/NCBI
|
35
|
Humbert J, Beyer K, Carrato C, Mate JL,
Ferrer I and Ariza A: Parkin and synphilin-1 isoform expression
changes in Lewy body diseases. Neurobiol Dis. 26:681–687. 2007.
View Article : Google Scholar : PubMed/NCBI
|
36
|
Tan EK, Shen H, Tan JM, Lim KL, Fook-Chong
S, Hu WP, Paterson MC, Chandran VR, Yew K, Tan C, et al:
Differential expression of splice variant and wild-type parkin in
sporadic Parkinson's disease. Neurogenetics. 6:179–184. 2005.
View Article : Google Scholar : PubMed/NCBI
|
37
|
Bouman L, Schlierf A, Lutz AK, Shan J,
Deinlein A, Kast J, Galehdar Z, Palmisano V, Patenge N, Berg D, et
al: Parkin is transcriptionally regulated by ATF4: Evidence for an
interconnection between mitochondrial stress and ER stress. Cell
Death Differ. 18:769–782. 2011. View Article : Google Scholar :
|
38
|
Narendra D, Tanaka A, Suen DF and Youle
RJ: Parkin is recruited selectively to impaired mitochondria and
promotes their autophagy. J Cell Biol. 183:795–803. 2008.
View Article : Google Scholar : PubMed/NCBI
|
39
|
Ikeuchi K, Marusawa H, Fujiwara M,
Matsumoto Y, Endo Y, Watanabe T, Iwai A, Sakai Y, Takahashi R and
Chiba T: Attenuation of proteolysis-mediated cyclin E regulation by
alternatively spliced Parkin in human colorectal cancers. Int J
Cancer. 125:2029–2035. 2009. View Article : Google Scholar : PubMed/NCBI
|
40
|
Klinkenberg M, Gispert S,
Dominguez-Bautista JA, Braun I, Auburger G and Jendrach M:
Restriction of trophic factors and nutrients induces PARKIN
expression. Neurogenetics. 13:9–21. 2012. View Article : Google Scholar :
|
41
|
Huynh DP, Scoles DR, Ho TH, Del Bigio MR
and Pulst SM: Parkin is associated with actin filaments in neuronal
and nonneural cells. Ann Neurol. 48:737–744. 2000. View Article : Google Scholar : PubMed/NCBI
|
42
|
D'Agata V, Grimaldi M, Pascale A and
Cavallaro S: Regional and cellular expression of the parkin gene in
the rat cerebral cortex. Eur J Neurosci. 12:3583–3588. 2000.
View Article : Google Scholar : PubMed/NCBI
|
43
|
D'Agata V, Zhao W, Pascale A, Zohar O,
Scapagnini G and Cavallaro S: Distribution of parkin in the adult
rat brain. Prog Neuropsychopharmacol Biol Psychiatry. 26:519–527.
2002. View Article : Google Scholar : PubMed/NCBI
|
44
|
Cookson MR, Lockhart PJ, McLendon C,
O'Farrell C, Schlossmacher M and Farrer MJ: RING finger 1 mutations
in Parkin produce altered localization of the protein. Hum Mol
Genet. 12:2957–2965. 2003. View Article : Google Scholar : PubMed/NCBI
|
45
|
Hampe C, Ardila-Osorio H, Fournier M,
Brice A and Corti O: Biochemical analysis of Parkinson's
disease-causing variants of Parkin, an E3 ubiquitin-protein ligase
with monoubiquitylation capacity. Hum Mol Genet. 15:2059–2075.
2006. View Article : Google Scholar : PubMed/NCBI
|
46
|
Sriram SR, Li X, Ko HS, Chung KK, Wong E,
Lim KL, Dawson VL and Dawson TM: Familial-associated mutations
differentially disrupt the solubility, localization, binding and
ubiquitination properties of parkin. Hum Mol Genet. 14:2571–2586.
2005. View Article : Google Scholar : PubMed/NCBI
|
47
|
Yamashita S and Okada Y: Application of
heat-induced antigen retrieval to aldehyde-fixed fresh frozen
sections. J Histochem Cytochem. 53:1421–1432. 2005. View Article : Google Scholar : PubMed/NCBI
|
48
|
Müller-Rischart AK, Pilsl A, Beaudette P,
Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn
PH, et al: The E3 ligase parkin maintains mitochondrial integrity
by increasing linear ubiquitination of NEMO. Mol Cell. 49:908–921.
2013. View Article : Google Scholar : PubMed/NCBI
|
49
|
Alves da Costa C and Checler F: Apoptosis
in Parkinson's disease: Is p53 the missing link between genetic and
sporadic Parkinsonism? Cell Signal. 23:963–968. 2011. View Article : Google Scholar
|