A morphometric study on the nuclear matrix of tumor cells in vitro

  • Authors:
    • L Yang
    • H Yam
    • S ChewCheng
    • W Cham
    • T Lam
    • E Chew
  • View Affiliations

  • Published online on: May 1, 1996     https://doi.org/10.3892/ijo.8.5.977
  • Pages: 977-981
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Abstract

Recently, we have demonstrated that two cervical carcinoma cell lines with different cell differentiation stages possessed different nuclear matrix stability. The nuclear matrix of poorly differentiated cells was more stable than that of the more differentiated one. In the present study, we further quantified the nuclear matrix density after treatment with different DNase I concentrations. Moreover, six more ovarian cell lines were also used to investigate the relationship between nuclear matrix stability and cell differentiation stages. Since the nuclear matrix is an important site for gene replication and transcription, the nuclear matrix stability can be used as an indicator to reflect these activities within the nucleus.

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May 1996
Volume 8 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Yang L, Yam H, ChewCheng S, Cham W, Lam T and Chew E: A morphometric study on the nuclear matrix of tumor cells in vitro. Int J Oncol 8: 977-981, 1996
APA
Yang, L., Yam, H., ChewCheng, S., Cham, W., Lam, T., & Chew, E. (1996). A morphometric study on the nuclear matrix of tumor cells in vitro. International Journal of Oncology, 8, 977-981. https://doi.org/10.3892/ijo.8.5.977
MLA
Yang, L., Yam, H., ChewCheng, S., Cham, W., Lam, T., Chew, E."A morphometric study on the nuclear matrix of tumor cells in vitro". International Journal of Oncology 8.5 (1996): 977-981.
Chicago
Yang, L., Yam, H., ChewCheng, S., Cham, W., Lam, T., Chew, E."A morphometric study on the nuclear matrix of tumor cells in vitro". International Journal of Oncology 8, no. 5 (1996): 977-981. https://doi.org/10.3892/ijo.8.5.977