Early Online

Open Access

Establishment of a novel human cell line retaining the characteristics of the original pancreatic adenocarcinoma, and evaluation of MEK as a therapeutic target

Xiaoxiao Du, Kuifeng He, Yingying Huang, Zhenzhen Xu, Mei Kong, Jing Zhang, Jiang Cao, Lisong Teng

Published online on: January 20, 2020
Open Access

New drugs are not enough‑drug repositioning in oncology: An update

Romina Gabriela Armando, Diego Luis Mengual Gómez, Daniel Eduardo Gomez

Published online on: January 20, 2020

CD24 and CK4 are upregulated by SIM2, and are predictive biomarkers for chemoradiotherapy and surgery in esophageal cancer

Kenji Takashima, Satoshi Fujii, Rie Komatsuzaki, Masayuki Komatsu, Mari Takahashi, Takashi Kojima, Hiroyuki Daiko, Keiko Minashi, Fumiko Chiwaki, Manabu Muto, Hiroki Sasaki, Tomonori Yano

Published online on: January 17, 2020
Open Access

FOXO3a‑SIRT6 axis suppresses aerobic glycolysis in melanoma

Zhen Dong, Jie Yang, Lin Li, Li Tan, Pengfei Shi, Jiayi Zhang, Xi Zhong, Lingjun Ge, Zonghui Wu, Hongjuan Cui

Published online on: January 17, 2020
Open Access

[Corrigendum]Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells

Tadashi Abe, The Mon La, Yuuzi Miyagaki, Eri Oya, Fan-Yan Wei, Kento Sumida, Kenshiro Fujise, Tetsuya Takeda, Kazuhito Tomizawa, Kohji Takei, Hiroshi Yamada

Published online on: January 16, 2020
Open Access

A novel loop‑mediated isothermal amplification method for efficient and robust detection of EGFR mutations

Sho Horiuchi, Yuichi Saito, Atsuka Matsui, Nobumasa Takahashi, Tomohiko Ikeya, Eishin Hoshi, Yoshihiko Shimizu, Masanori Yasuda

Published online on: January 14, 2020

Long non‑coding RNA profile revealed by microarray indicates that lncCUEDC1 serves a negative regulatory role in breast cancer stem cells

Fengchun Zhang, Yue Ma, Liang Xu, Haiyan Xu, Yingchun Xu, Ningning Yan

Published online on: January 13, 2020
Open Access

Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells

Zhong Hong, Zhaohong Wang, Bin Zhou, Jisheng Wang, Hongfei Tong, Yi Liao, Peng Zheng, Muhammad Babar Jamshed, Qiyu Zhang, Hui Chen

Published online on: January 10, 2020
Open Access

Iodine‑131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma

Ana Filipa Brito, Ana Margarida Abrantes, Ricardo Teixo, Ana Salomé Pires, Ana Cláudia Ribeiro, Rafael Fernandes Ferreira, Alexandra Fernandes, Tiago Puga, Mafalda Laranjo, Francisco Caramelo, Ilka Boin, Douglas M. Jefferson, Ana Cristina Gonçalves, Ricardo Martins, Joana Rodrigues, Ilda Patrícia Ribeiro, Joana Barbosa De Melo, Ana Bela Sarmento-Ribeiro, Isabel Marques Carreira, Doroteia Souza, José Guilherme Tralhão, Maria Filomena Botelho

Published online on: January 10, 2020
Open Access

PAX2 promotes epithelial ovarian cancer progression involving fatty acid metabolic reprogramming

Yan Feng, Yong Tang, Yannan Mao, Yingzhao Liu, Desheng Yao, Linkai Yang, Kenneth Garson, Barbara C. Vanderhyden, Qi Wang

Published online on: January 10, 2020
Open Access

Overexpression of PRC1 indicates a poor prognosis in ovarian cancer

Hualei Bu, Yingwei Li, Chengjuan Jin, Hongfeng Yu, Xiangxiang Wang, Jingying Chen, Yu Wang, Yana Ma, Youzhong Zhang, Beihua Kong

Published online on: January 10, 2020