Open Access

Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report

  • Authors:
    • Toru Sakatani
    • Yoshinaga Okumura
    • Naoto Kuroda
    • Toshihiro Magaribuchi
    • Yorika Nakano
    • Toshiaki Shirahase
    • Jun Watanabe
    • Yoji Taki
    • Mitsuhiko Okigaki
    • Susumu Ikehara
    • Yasushi Adachi
  • View Affiliations

  • Published online on: September 29, 2017     https://doi.org/10.3892/mco.2017.1430
  • Pages:976-980
  • Copyright: © Sakatani et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) is rare in renal cell carcinoma (RCC) and usually demonstrates a low nuclear grade and a better prognosis compared with other RCCs. The authors present a case report of MTSCC containing an area of Fuhrman nuclear grade 3, in addition to an area with a micropapillary pattern. An 82‑year‑old man consulted a hospital due to macrohematuria, and a tumor in the right kidney was detected. The tumor was resected and histologically examined. The tumor consisted of various growth patterns: Elongated tubular structure, a papillary structure containing a micropapillary pattern and solid pattern with spindle cells. The tumor cells demonstrated Fuhrman nuclear grades 2 and 3. Invasion into the lymph vessel and metastasis into the regional lymph node were observed. Thus, the tumor was diagnosed as a high grade MTSCC. Five months following resection, a computed tomography scan suggested metastasis of the tumor into the para‑aortic lymph nodes and liver, and the patient succumbed to brain metastasis. When MTSCC of kidney is observed, careful histological observation is important to avoid missing a high nuclear grade area.

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December 2017
Volume 7 Issue 6

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
Sakatani, T., Okumura, Y., Kuroda, N., Magaribuchi, T., Nakano, Y., Shirahase, T. ... Adachi, Y. (2017). Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report. Molecular and Clinical Oncology, 7, 976-980. https://doi.org/10.3892/mco.2017.1430
MLA
Sakatani, T., Okumura, Y., Kuroda, N., Magaribuchi, T., Nakano, Y., Shirahase, T., Watanabe, J., Taki, Y., Okigaki, M., Ikehara, S., Adachi, Y."Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report". Molecular and Clinical Oncology 7.6 (2017): 976-980.
Chicago
Sakatani, T., Okumura, Y., Kuroda, N., Magaribuchi, T., Nakano, Y., Shirahase, T., Watanabe, J., Taki, Y., Okigaki, M., Ikehara, S., Adachi, Y."Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report". Molecular and Clinical Oncology 7, no. 6 (2017): 976-980. https://doi.org/10.3892/mco.2017.1430