Ruptured hepatoblastoma successfully treated with cisplatin monochemotherapy: A case report

  • Authors:
    • Tianyou Yang
    • Tianbao Tan
    • Jiliang Yang
    • Jing Pan
    • Chao Hu
    • Jiahao Li
    • Tao Xu
    • Yan Zou
  • View Affiliations

  • Published online on: June 4, 2018     https://doi.org/10.3892/mco.2018.1643
  • Pages: 223-225
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Abstract

Traditionally, ruptured hepatoblastoma is considered a high-risk occurrence, necessitating a chemotherapy regimen usually consisting of cisplatin alternating with carboplatin plus doxorubicin, based on International Childhood Liver Tumours Strategy Group studies. However, ruptured hepatoblastomas with intact hepatic capsules may represent a unique subgroup that may be successfully treated with TAE, cisplatin monotherapy, and surgical excision. We herein present a case of ruptured hepatoblastoma (pretreatment tumor extension stage II) in a 1-year-old female patient that was successfully managed with transarterial embolization (TAE), eight courses of cisplatin chemotherapy and surgical removal. The patient currently remains disease-free for >12 months. Given the rarity of ruptured hepatoblastomas, further study of patients within this subgroup is required to confirm the findings of the present study.
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August-2018
Volume 9 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Yang T, Tan T, Yang J, Pan J, Hu C, Li J, Xu T and Zou Y: Ruptured hepatoblastoma successfully treated with cisplatin monochemotherapy: A case report. Mol Clin Oncol 9: 223-225, 2018
APA
Yang, T., Tan, T., Yang, J., Pan, J., Hu, C., Li, J. ... Zou, Y. (2018). Ruptured hepatoblastoma successfully treated with cisplatin monochemotherapy: A case report. Molecular and Clinical Oncology, 9, 223-225. https://doi.org/10.3892/mco.2018.1643
MLA
Yang, T., Tan, T., Yang, J., Pan, J., Hu, C., Li, J., Xu, T., Zou, Y."Ruptured hepatoblastoma successfully treated with cisplatin monochemotherapy: A case report". Molecular and Clinical Oncology 9.2 (2018): 223-225.
Chicago
Yang, T., Tan, T., Yang, J., Pan, J., Hu, C., Li, J., Xu, T., Zou, Y."Ruptured hepatoblastoma successfully treated with cisplatin monochemotherapy: A case report". Molecular and Clinical Oncology 9, no. 2 (2018): 223-225. https://doi.org/10.3892/mco.2018.1643