1
|
Xiao S and Zhou L: Gastric cancer:
Metabolic and metabolomics perspectives (Review). Int J Oncol.
51:5–17. 2017. View Article : Google Scholar : PubMed/NCBI
|
2
|
Hartgrink HH, Jansen EP, van Grieken NC
and van de Velde CJ: Gastric cancer. Lancet. 374:477–490. 2009.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Greenspan EM: Adjuvant chemotherapy for
stomach cancer. Lancet. 1:1459–1460. 1989. View Article : Google Scholar : PubMed/NCBI
|
4
|
MacDonald JS, Schein PS, Woolley PV,
Smythe T, Ueno W, Hoth D, Smith F, Boiron M, Gisselbrecht C, Brunet
R and Lagarde C: 5-Fluorouracil, doxorubicin, and mitomycin (FAM)
combination chemotherapy for advanced gastric cancer. Ann Intern
Med. 93:533–536. 1980. View Article : Google Scholar : PubMed/NCBI
|
5
|
Longley DB, Harkin DP and Johnston PG:
5-fluorouracil: Mechanisms of action and clinical strategies. Nat
Rev Cancer. 3:330–338. 2003. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Wohlhueter RM, McIvor RS and Plagemann PG:
Facilitated transport of uracil and 5-fluorouracil, and permeation
of orotic acid into cultured mammalian cells. J Cell Physiol.
104:309–319. 1980. View Article : Google Scholar : PubMed/NCBI
|
7
|
Rani I, Sharma B, Kumar S, Kaur S and
Agnihotri N: Apoptosis mediated chemosensitization of tumor cells
to 5-fluorouracil on supplementation of fish oil in experimental
colon carcinoma. Tumour Biol. 39:10104283176950192017. View Article : Google Scholar : PubMed/NCBI
|
8
|
Wu J, Hu D and Zhang R: Depletion of Bmi-1
enhances 5-fluorouracil-induced apoptosis and autophagy in
hepatocellular carcinoma cells. Oncol Lett. 4:723–726. 2012.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Yao CW, Kang KA, Piao MJ, Ryu YS, Fernando
PMDJ, Oh MC, Park JE, Shilnikova K, Na SY, Jeong SU, et al: Reduced
autophagy in 5-fluorouracil resistant colon cancer cells. Biomol
Ther. 25:315–320. 2017. View Article : Google Scholar
|
10
|
Suzuki R, Kang Y, Li X, Roife D, Zhang R
and Fleming JB: Genistein potentiates the antitumor effect of
5-Fluorouracil by inducing apoptosis and autophagy in human
pancreatic cancer cells. Anticancer Res. 34:4685–4692.
2014.PubMed/NCBI
|
11
|
Mizushima N: Autophagy: Process and
function. Genes Dev. 21:2861–2873. 2007. View Article : Google Scholar : PubMed/NCBI
|
12
|
Mathew R, Karantza-Wadsworth V and White
E: Role of autophagy in cancer. Nat Rev Cancer. 7:961–967. 2007.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Singh SS, Vats S, Chia AY, Tan TZ, Deng S,
Ong MS, Arfuso F, Yap CT, Goh BC, Sethi G, et al: Dual role of
autophagy in hallmarks of cancer. Oncogene. 2017.Doi:
10.1038/s41388-017-0046-6.
|
14
|
Chen HY and White E: Role of autophagy in
cancer prevention. Cancer Prev Res. 4:973–983. 2011. View Article : Google Scholar
|
15
|
Guarente L: Introduction: Sirtuins in
aging and diseases. Methods Mol Biol. 1077:3–10. 2013. View Article : Google Scholar : PubMed/NCBI
|
16
|
Qiu G, Li X, Wei C, Che X, He S, Lu J,
Wang S, Pang K and Fan L: The prognostic role of SIRT1-autophagy
axis in gastric cancer. Dis Markers. 2016:68694152016. View Article : Google Scholar : PubMed/NCBI
|
17
|
Gal J, Bang Y and Choi HJ: SIRT2
interferes with autophagy-mediated degradation of protein
aggregates in neuronal cells under proteasome inhibition. Neurochem
Int. 61:992–1000. 2012. View Article : Google Scholar : PubMed/NCBI
|
18
|
Cho CS, Lombard DB and Lee JH: SIRT3 as a
regulator of hepatic autophagy. Hepatology. 66:700–702. 2017.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Polletta L, Vernucci E, Carnevale I,
Arcangeli T, Rotili D, Palmerio S, Steegborn C, Nowak T,
Schutkowski M, Pellegrini L, et al: SIRT5 regulation of
ammonia-induced autophagy and mitophagy. Autophagy. 11:253–270.
2015. View Article : Google Scholar : PubMed/NCBI
|
20
|
Takasaka N, Araya J, Hara H, Ito S,
Kobayashi K, Kurita Y, Wakui H, Yoshii Y, Yumino Y, Fujii S, et al:
Autophagy induction by SIRT6 through attenuation of insulin-like
growth factor signaling is involved in the regulation of human
bronchial epithelial cell senescence. J Immunol. 192:958–968. 2014.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔCT method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Tang JC, Feng YL, Liang X and Cai XJ:
Autophagy in 5-fluorouracil therapy in gastrointestinal cancer:
Trends and challenges. Chin Med J. 129:456–463. 2016. View Article : Google Scholar : PubMed/NCBI
|
23
|
Kimura S, Fujita N, Noda T and Yoshimori
T: Monitoring autophagy in mammalian cultured cells through the
dynamics of LC3. Methods Enzymol. 452:1–12. 2009. View Article : Google Scholar : PubMed/NCBI
|
24
|
Hu Y, Liu J, Wu YF, Lou J, Mao YY, Shen HH
and Chen ZH: mTOR and autophagy in regulation of acute lung injury:
A review and perspective. Microbes Infect. 16:727–734. 2014.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Petibone DM, Majeed W and Casciano DA:
Autophagy function and its relationship to pathology, clinical
applications, drug metabolism and toxicity. J Appl Toxicol.
37:23–37. 2017. View
Article : Google Scholar : PubMed/NCBI
|
26
|
Liang XH, Jackson S, Seaman M, Brown K,
Kempkes B, Hibshoosh H and Levine B: Induction of autophagy and
inhibition of tumorigenesis by beclin 1. Nature. 402:672–676. 1999.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Hu F, Guo XL, Zhang SS, Zhao QD, Li R, Xu
Q and Wei LX: Suppression of p53 potentiates chemosensitivity in
nutrient-deprived cholangiocarcinoma cells via inhibition of
autophagy. Oncol Lett. 14:1959–1966. 2017. View Article : Google Scholar : PubMed/NCBI
|
28
|
Inada T, Ichikawa A, Igarashi S, Kubota T
and Ogata Y: Effect of preoperative 5-fluorouracil on apoptosis of
advanced gastric cancer. J Surg Oncol. 65:106–110. 1997. View Article : Google Scholar : PubMed/NCBI
|
29
|
Klionsky DJ, Abdelmohsen K, Abe A, Abedin
MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD,
Adeli K, et al: Guidelines for the use and interpretation of assays
for monitoring autophagy (3rd edition). Autophagy. 12:1–222. 2016.
View Article : Google Scholar : PubMed/NCBI
|
30
|
Wang L, Gao C, Yao S and Xie B: Blocking
autophagic flux enhances matrine-induced apoptosis in human
hepatoma cells. Int J Mol Sci. 14:23212–23230. 2013. View Article : Google Scholar : PubMed/NCBI
|
31
|
Xie BS, Zhao HC, Yao SK, Zhuo DX, Jin B,
Lv DC, Wu CL, Ma DL, Gao C, Shu XM and Ai ZL: Autophagy inhibition
enhances etoposide-induced cell death in human hepatoma G2 cells.
Int J Mol Med. 27:599–606. 2011.PubMed/NCBI
|
32
|
Xie SB, He XX and Yao SK: Matrine-induced
autophagy regulated by p53 through AMP-activated protein kinase in
human hepatoma cells. Int J Oncol. 47:517–526. 2015. View Article : Google Scholar : PubMed/NCBI
|
33
|
Tylichová Z, Straková N, Vondráček J,
Vaculová AH, Kozubík A and Hofmanová J: Activation of autophagy and
PPARγ protect colon cancer cells against apoptosis induced by
interactive effects of butyrate and DHA in a cell type-dependent
manner: The role of cell differentiation. J Nutr Biochem.
39:145–155. 2017. View Article : Google Scholar : PubMed/NCBI
|
34
|
Liu Z, Xu J, He J, Liu H, Lin P, Wan X,
Navone NM, Tong Q, Kwak LW, Orlowski RZ and Yang J: Mature
adipocytes in bone marrow protect myeloma cells against
chemotherapy through autophagy activation. Oncotarget.
6:34329–34341. 2015. View Article : Google Scholar : PubMed/NCBI
|
35
|
Zhang L, Zhang J, Chen L and Wang J:
Autophagy in human skin squamous cell carcinoma: Inhibition by 3-MA
enhances the effect of 5-FU-induced chemotherapy sensitivity. Oncol
Rep. 34:3147–3155. 2015. View Article : Google Scholar : PubMed/NCBI
|
36
|
Colell A, Ricci JE, Tait S, Milasta S,
Maurer U, Bouchier-Hayes L, Fitzgerald P, Guio-Carrion A,
Waterhouse NJ, Li CW, et al: GAPDH and autophagy preserve survival
after apoptotic cytochrome c release in the absence of
caspase activation. Cell. 129:983–997. 2007. View Article : Google Scholar : PubMed/NCBI
|
37
|
Degenhardt K, Mathew R, Beaudoin B, Bray
K, Anderson D, Chen G, Mukherjee C, Shi Y, Gélinas C, Fan Y, et al:
Autophagy promotes tumor cell survival and restricts necrosis,
inflammation, and tumorigenesis. Cancer Cell. 10:51–64. 2006.
View Article : Google Scholar : PubMed/NCBI
|
38
|
Dai Y and Faller DV: Transcription
regulation by class III histone deacetylases (HDACs)-sirtuins.
Transl Oncogenomics. 3:53–65. 2008.PubMed/NCBI
|
39
|
Chalkiadaki A and Guarente L: The
multifaceted functions of sirtuins in cancer. Nat Rev Cancer.
15:608–624. 2015. View
Article : Google Scholar : PubMed/NCBI
|
40
|
He J, Zhang G, Pang Q, Yu C, Xiong J, Zhu
J and Chen F: SIRT6 reduces macrophage foam cell formation by
inducing autophagy and cholesterol efflux under ox-LDL condition.
FEBS J. 284:1324–1337. 2017. View Article : Google Scholar : PubMed/NCBI
|
41
|
Qiu G, Li X, Che X, Wei C, He S, Lu J, Jia
Z, Pang K and Fan L: SIRT1 is a regulator of autophagy:
Implications in gastric cancer progression and treatment. FEBS
Lett. 589:2034–2042. 2015. View Article : Google Scholar : PubMed/NCBI
|
42
|
Sun T, Li X, Zhang P, Chen WD, Zhang HL,
Li DD, Deng R, Qian XJ, Jiao L, Ji J, et al: Acetylation of Beclin
1 inhibits autophagosome maturation and promotes tumour growth. Nat
Commun. 6:72152015. View Article : Google Scholar : PubMed/NCBI
|