Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review)

  • Authors:
    • Chi Liu
    • Xun Zhang
    • Yang Xiang
    • Xiangping Qu
    • Huijun Liu
    • Caixia Liu
    • Meiling Tan
    • Jianxin Jiang
    • Xiaoqun Qin
  • View Affiliations

  • Published online on: March 14, 2018     https://doi.org/10.3892/mmr.2018.8739
  • Pages: 6935-6941
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Abstract

As the first barrier to the outside environment, airway epithelial cells serve a central role in the initiation and development of airway inflammation. Chemokines are the most direct and immediate cell factors for the recruitment and migration of inflammatory cells. The present review focused on the role of epithelial chemokines in the pathogenesis of airway inflammation in asthma. In addition to traditional CC family chemokines and CXC family chemokines, airway epithelial cells also express other chemokines, including thymic stromal lymphopoietin and interleukin‑33. By expressing and secreting chemokines, airway epithelial cells serve a key role in orchestrating airway inflammation in asthma.
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May-2018
Volume 17 Issue 5

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Liu C, Zhang X, Xiang Y, Qu X, Liu H, Liu C, Tan M, Jiang J and Qin X: Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review). Mol Med Rep 17: 6935-6941, 2018
APA
Liu, C., Zhang, X., Xiang, Y., Qu, X., Liu, H., Liu, C. ... Qin, X. (2018). Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review). Molecular Medicine Reports, 17, 6935-6941. https://doi.org/10.3892/mmr.2018.8739
MLA
Liu, C., Zhang, X., Xiang, Y., Qu, X., Liu, H., Liu, C., Tan, M., Jiang, J., Qin, X."Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review)". Molecular Medicine Reports 17.5 (2018): 6935-6941.
Chicago
Liu, C., Zhang, X., Xiang, Y., Qu, X., Liu, H., Liu, C., Tan, M., Jiang, J., Qin, X."Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review)". Molecular Medicine Reports 17, no. 5 (2018): 6935-6941. https://doi.org/10.3892/mmr.2018.8739