1
|
Wei X, Zhao D, Wang B, Wang W, Kang K, Xie
H, Liu B, Zhang X, Zhang J and Yang Z: Tantalum coating of porous
carbon scaffold supplemented with autologous bone marrow stromal
stem cells for bone regeneration in vitro and in vivo. Exp Biol Med
(Maywood). 241:592–602. 2016. View Article : Google Scholar : PubMed/NCBI
|
2
|
Su N, Gao PL, Wang K, Wang JY, Zhong Y and
Luo Y: Fibrous scaffolds potentiate the paracrine function of
mesenchymal stem cells: A new dimension in cell-material
interaction. Biomaterials. 141:74–85. 2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Xia Y, Sun J, Zhao L, Zhang F, Liang XJ,
Guo Y, Weir MD, Reynolds MA, Gu N and Xu HHK: Magnetic field and
nano-scaffolds with stem cells to enhance bone regeneration.
Biomaterials. 183:151–170. 2018. View Article : Google Scholar : PubMed/NCBI
|
4
|
Hallam P, Haddad F and Cobb J: Pain in the
well-fixed, aseptic titanium hip replacement. The role of
corrosion. J Bone Joint Surg Br. 86:27–30. 2004. View Article : Google Scholar : PubMed/NCBI
|
5
|
Zhang X, Zu H, Zhao D, Yang K, Tian S, Yu
X, Lu F, Liu B, Yu X, Wang B, et al: Ion channel functional protein
kinase TRPM7 regulates Mg ions to promote the osteoinduction of
human osteoblast via PI3K pathway: In vitro simulation of the
bone-repairing effect of Mg-based alloy implant. Acta Biomater.
63:369–382. 2017. View Article : Google Scholar : PubMed/NCBI
|
6
|
Lin D, Zuo S, Li L, Wang L and Lian K:
Treatment of neglected femoral neck fractures using the modified
dynamic hip screw with autogenous bone and bone morphogenetic
protein-2 composite materials grafting. Indian J Orthop.
49:342–346. 2015. View Article : Google Scholar : PubMed/NCBI
|
7
|
Moore NM, Lin NJ, Gallant ND and Becker
ML: Synergistic enhancement of human bone marrow stromal cell
proliferation and osteogenic differentiation on BMP-2-derived and
RGD peptide concentration gradients. Acta Biomater. 7:2091–2100.
2011. View Article : Google Scholar : PubMed/NCBI
|
8
|
Piek E, Sleumer LS, van Someren EP, Heuver
L, de Haan JR, de Grijs I, Gilissen C, Hendriks JM, van
Ravestein-van Os RI, Bauerschmidt S, et al: Osteo-transcriptomics
of human mesenchymal stem cells: Accelerated gene expression and
osteoblast differentiation induced by vitamin D reveals c-MYC as an
enhancer of BMP2-induced osteogenesis. Bone. 46:613–627. 2010.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Poh CK, Shi Z, Lim TY, Neoh KG and Wang W:
The effect of VEGF functionalization of titanium on endothelial
cells in vitro. Biomaterials. 31:1578–1585. 2010. View Article : Google Scholar : PubMed/NCBI
|
10
|
Geiger F, Beverungen M, Lorenz H, Wieland
J, Fehr M and Kasten P: Bone substitute effect on vascularization
and bone remodeling after application of phVEGF165 transfected
BMSC. J Funct Biomater. 3:313–326. 2012. View Article : Google Scholar : PubMed/NCBI
|
11
|
Yu H, Zeng X, Deng C, Shi C, Ai J and Leng
W: Exogenous VEGF introduced by bioceramic composite materials
promotes the restoration of bone defect in rabbits. Biomed
Pharmacother. 98:325–332. 2018. View Article : Google Scholar : PubMed/NCBI
|
12
|
Ueland T, Lekva T, Otterdal K, Dahl TB,
Olarescu NC, Jørgensen AP, Fougner KJ, Brixen K, Aukrust P and
Bollerslev J: Increased serum and bone matrix levels of
transforming growth factor {beta}1 in patients with GH deficiency
in response to GH treatment. Eur J Endocrinol. 165:393–400. 2011.
View Article : Google Scholar : PubMed/NCBI
|
13
|
Bonewald LF and Dallas SL: Role of active
and latent transforming growth factor beta in bone formation. J
Cell Biochem. 55:350–357. 1994. View Article : Google Scholar : PubMed/NCBI
|
14
|
Zhao Y, Li Y, Gao Y, Yuan M, Manthari RK
and Wang J and Wang J: TGF-β1 acts as mediator in fluoride-induced
autophagy in the mouse osteoblast cells. Food Chem Toxicol.
115:26–33. 2018. View Article : Google Scholar : PubMed/NCBI
|
15
|
Siegel PM and Massagué J: Cytostatic and
apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev
Cancer. 3:807–821. 2003. View
Article : Google Scholar : PubMed/NCBI
|
16
|
Lind M: Growth factor stimulation of bone
healing. Effects on osteoblasts, osteomies, and implants fixation.
Acta Orthop Scand Suppl. 283:2–37. 1998.PubMed/NCBI
|
17
|
Duan X, Liu J, Zheng X, Wang Z, Zhang Y,
Hao Y, Yang T and Deng H: Deficiency of ATP6V1H causes bone loss by
inhibiting bone resorption and bone formation through the TGF-β1
pathway. Theranostics. 6:2183–2195. 2016. View Article : Google Scholar : PubMed/NCBI
|
18
|
Marcelli C, Yates AJ and Mundy GR: In vivo
effects of human recombinant transforming growth factor beta on
bone turnover in normal mice. J Bone Miner Res. 5:1087–1096. 1990.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Chen LJ, Chen C, Qiao XY, Yu K, Xie LZ,
Cao J, Liu BL and Yan Y: Effect of porous titanium coated with
IGF-1 and TGF-β1 loaded gelatin microsphere on function
of MG63 cells. Transact Nonferr Metals Soc China. 25:2974–2985.
2015. View Article : Google Scholar
|
20
|
Lamberg A, Schmidmaier G, Søballe K and
Elmengaard B: Locally delivered TGF-beta1 and IGF-1 enhance the
fixation of titanium implants: A study in dogs. Acta Orthop.
77:799–805. 2006. View Article : Google Scholar : PubMed/NCBI
|
21
|
Feng XH and Derynck R: Specificity and
versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev
Biol. 21:659–693. 2005. View Article : Google Scholar : PubMed/NCBI
|
22
|
Karst M, Gorny G, Galvin RJ and Oursler
MJ: Roles of stromal cell RANKL, OPG, and M-CSF expression in
biphasic TGF-beta regulation of osteoclast differentiation. J Cell
Physiol. 200:99–106. 2004. View Article : Google Scholar : PubMed/NCBI
|
23
|
Chen G, Deng C and Li YP: TGF-β and BMP
signaling in osteoblast differentiation and bone formation. Int J
Biol Sci. 8:272–288. 2012. View Article : Google Scholar : PubMed/NCBI
|
24
|
Kang JS, Alliston T, Delston R and Derynck
R: Repression of Runx2 function by TGF-beta through recruitment of
class II histone deacetylases by Smad3. EMBO J. 24:2543–2555. 2005.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Xie F, Ling L, van Dam H, Zhou F and Zhang
L: TGF-β signaling in cancer metastasis. Acta Biochim Biophys Sin
(Shanghai). 50:121–132. 2018. View Article : Google Scholar : PubMed/NCBI
|
26
|
Wang J, Ma XY, Feng YF, Ma ZS, Ma TC,
Zhang Y, Li X, Wang L and Lei W: Magnesium ions promote the
biological behaviour of rat calvarial osteoblasts by activating the
PI3K/Akt signalling pathway. Biol Trace Elem Res. 179:284–293.
2017. View Article : Google Scholar : PubMed/NCBI
|
27
|
Bertacchini J, Heidari N, Mediani L,
Capitani S, Shahjahani M, Ahmadzadeh A and Saki N: Targeting
PI3K/AKT/mTOR network for treatment of leukemia. Cell Mol Life Sci.
72:2337–2347. 2015. View Article : Google Scholar : PubMed/NCBI
|
28
|
Manfredi GI, Dicitore A, Gaudenzi G,
Caraglia M, Persani L and Vitale G: PI3K/Akt/mTOR signaling in
medullary thyroid cancer: A promising molecular target for cancer
therapy. Endocrine. 48:363–370. 2015. View Article : Google Scholar : PubMed/NCBI
|
29
|
Golub EE, Harrison G, Taylor AG, Camper S
and Shapiro IM: The role of alkaline phosphatase in cartilage
mineralization. Bone Miner. 17:273–278. 1992. View Article : Google Scholar : PubMed/NCBI
|
30
|
Luo G, Xu B and Huang Y: Icariside II
promotes the osteogenic differentiation of canine bone marrow
mesenchymal stem cells via the PI3K/AKT/mTOR/S6K1 signaling
pathways. Am J Transl Res. 9:2077–2087. 2017.PubMed/NCBI
|
31
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
32
|
Chen Q, Zhu C and Thouas GA: Progress and
challenges in biomaterials used for bone tissue engineering:
Bioactive glasses and elastomeric composites. Prog Biomater.
1:22012. View Article : Google Scholar : PubMed/NCBI
|
33
|
Chen X, Lu J, Ji Y, Hong A and Xie Q:
Cytokines in osteoblast-conditioned medium promote the migration of
breast cancer cells. Tumour Biol. 35:791–798. 2014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Hughes FJ, Turner W, Belibasakis G and
Martuscelli G: Effects of growth factors and cytokines on
osteoblast differentiation. Periodontol 2000. 41:48–72. 2006.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Janssens K, ten Dijke P, Janssens S and
Van Hul W: Transforming growth factor-beta1 to the bone. Endocr
Rev. 26:743–774. 2005. View Article : Google Scholar : PubMed/NCBI
|
36
|
Ota K, Quint P, Ruan M, Pederson L,
Westendorf JJ, Khosla S and Oursler MJ: TGF-β induces Wnt10b in
osteoclasts from female mice to enhance coupling to osteoblasts.
Endocrinology. 154:3745–3752. 2013. View Article : Google Scholar : PubMed/NCBI
|
37
|
Kanaan RA and Kanaan LA: Transforming
growth factor beta1, bone connection. Med Sci Monit.
12:RA164–RA169. 2006.PubMed/NCBI
|
38
|
Wang X, Dong F, Zhang S, Yang W, Yu W,
Wang Z, Zhang S, Wang J, Ma S, Wu P, et al: TGF-beta1 negatively
regulates the number and function of hematopoietic stem cells. Stem
Cell Reports. 11:274–287. 2018. View Article : Google Scholar : PubMed/NCBI
|
39
|
Matsunobu T, Torigoe K, Ishikawa M, de
Vega S, Kulkarni AB, Iwamoto Y and Yamada Y: Critical roles of the
TGF-beta type I receptor ALK5 in perichondrial formation and
function, cartilage integrity, and osteoblast differentiation
during growth plate development. Dev Biol. 332:325–338. 2009.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Ramirez-Yañez GO, Hamlet S, Jonarta A,
Seymour GJ and Symons AL: Prostaglandin E2 enhances transforming
growth factor-beta 1 and TGF-beta receptors synthesis: An in vivo
and in vitro study. Prostaglandins Leukot Essent Fatty Acids.
74:183–192. 2006. View Article : Google Scholar : PubMed/NCBI
|
41
|
Cantrell DA: Phosphoinositide 3-kinase
signalling pathways. J Cell Sci. 114:1439–1445. 2001.PubMed/NCBI
|
42
|
Cantley LC: The phosphoinositide 3-kinase
pathway. Science. 296:1655–1657. 2002. View Article : Google Scholar : PubMed/NCBI
|
43
|
Guntur AR and Rosen CJ: The skeleton: A
multi-functional complex organ: New insights into osteoblasts and
their role in bone formation: The central role of PI3Kinase. J
Endocrinol. 211:123–130. 2011. View Article : Google Scholar : PubMed/NCBI
|
44
|
Mukherjee A and Rotwein P: Akt promotes
BMP2-mediated osteoblast differentiation and bone development. J
Cell Sci. 122:716–726. 2009. View Article : Google Scholar : PubMed/NCBI
|
45
|
Kristensen HB, Andersen TL, Marcussen N,
Rolighed L and Delaisse JM: Osteoblast recruitment routes in human
cancellous bone remodeling. Am J Pathol. 184:778–789. 2014.
View Article : Google Scholar : PubMed/NCBI
|
46
|
Maes C, Kobayashi T, Selig MK, Torrekens
S, Roth SI, Mackem S, Carmeliet G and Kronenberg HM: Osteoblast
precursors, but not mature osteoblasts, move into developing and
fractured bones along with invading blood vessels. Dev Cell.
19:329–344. 2010. View Article : Google Scholar : PubMed/NCBI
|
47
|
Ota K, Quint P, Weivoda MM, Ruan M,
Pederson L, Westendorf JJ, Khosla S and Oursler MJ: Transforming
growth factor beta 1 induces CXCL16 and leukemia inhibitory factor
expression in osteoclasts to modulate migration of osteoblast
progenitors. Bone. 57:68–75. 2013. View Article : Google Scholar : PubMed/NCBI
|
48
|
Fie C, Guo J, Zhao Y, Gu S, Zhao S, Li X
and Chang C: Notch-Hes pathway mediates the impaired osteogenic
differentiation of bone marrow mesenchymal stromal cells from
myelodysplastic syndromes patients through the down-regulation of
Runx2. Am J Transl Res. 7:1939–1951. 2015.PubMed/NCBI
|
49
|
Kumar Y, Kapoor I, Khan K, Thacker G, Khan
MP, Shukla N, Kanaujiya JK, Sanyal S, Chattopadhyay N and Trivedi
AK: E3 ubiquitin ligase Fbw7 negatively regulates osteoblast
differentiation by targeting Runx2 for degradation. J Biol Chem.
290:30975–30987. 2015. View Article : Google Scholar : PubMed/NCBI
|
50
|
Gersbach CA, Byers BA, Pavlath GK and
García AJ: Runx2/Cbfa1 stimulates transdifferentiation of primary
skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp
Cell Res. 300:406–417. 2004. View Article : Google Scholar : PubMed/NCBI
|
51
|
Creff G, Safi S, Roques J, Michel H,
Jeanson A, Solari PL, Basset C, Simoni E, Vidaud C and Den Auwer C:
Actinide(IV) deposits on bone: Potential role of the
osteopontin-thorium complex. Inorg Chem. 55:29–36. 2016. View Article : Google Scholar : PubMed/NCBI
|
52
|
Schwetz V, Pieber T and Obermayer-Pietsch
B: The endocrine role of the skeleton: Background and clinical
evidence. Eur J Endocrinol. 166:959–967. 2012. View Article : Google Scholar : PubMed/NCBI
|
53
|
Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD,
Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, et al:
Endocrine regulation of energy metabolism by the skeleton. Cell.
130:456–469. 2007. View Article : Google Scholar : PubMed/NCBI
|
54
|
Renn J and Winkler C: Osterix/Sp7
regulates biomineralization of otoliths and bone in medaka (Oryzias
latipes). Matrix Biol. 34:193–204. 2014. View Article : Google Scholar : PubMed/NCBI
|
55
|
Dong Q, Fu L, Zhao Y, Tan S and Wang E:
Derlin-1 overexpression confers poor prognosis in muscle invasive
bladder cancer and contributes to chemoresistance and invasion
through PI3K/AKT and ERK/MMP signaling. Oncotarget. 8:17059–17069.
2017.PubMed/NCBI
|
56
|
Huang J and Manning BD: The TSC1-TSC2
complex: A molecular switchboard controlling cell growth. Biochem
J. 412:179–190. 2008. View Article : Google Scholar : PubMed/NCBI
|
57
|
Magnuson B, Ekim B and Fingar D:
Regulation and function of ribosomal protein S6 kinase (S6K) within
mTOR signalling networks. Biochem J. 441:1–21. 2012. View Article : Google Scholar : PubMed/NCBI
|
58
|
Swiech L, Perycz M, Malik A and Jaworski
J: Role of mTOR in physiology and pathology of the nervous system.
Biochim Biophys Acta. 1784:116–132. 2008. View Article : Google Scholar : PubMed/NCBI
|
59
|
Inoki K, Ouyang H, Li Y and Guan KL:
Signaling by target of rapamycin proteins in cell growth control.
Microbiol Mol Biol Rev. 69:79–100. 2005. View Article : Google Scholar : PubMed/NCBI
|