Early Online

Open Access

MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo

Mingfen Lv, Zhengjun Li, Jingjing Liu, Fan Lin, Qianwen Zhang, Zhiming Li, Yi Wang, Keyu Wang, Yunsheng Xu

Published online on: August 23, 2019
Open Access

Integrative genomics analysis of hub genes and their relationship with prognosis and signaling pathways in esophageal squamous cell carcinoma

Fang‑Fang Chen, Shi‑Rong Zhang, Hao Peng, Yun‑Zhao Chen, Xiao‑Bin Cui

Published online on: August 23, 2019
Open Access

Glycylglycine plays critical roles in the proliferation of spermatogonial stem cells

Bo Xu, Xiang Wei, Minjian Chen, Kaipeng Xie, Yuqing Zhang, Zhenyao Huang, Tianyu Dong, Weiyue Hu, Kun Zhou, Xiumei Han, Xin Wu, Yankai Xia

Published online on: August 23, 2019
Open Access

Rsf‑1 regulates malignant melanoma cell viability and chemoresistance via NF‑κB/Bcl‑2 signaling

Jiani He, Lin Fu, Qingchang Li

Published online on: August 23, 2019

miR‑497 inhibits the proliferation and migration of A549 non‑small‑cell lung cancer cells by targeting FGFR1

Qibin Huang, Hongtao Li, Xiaofeng Dai, Di Zhao, Bingfeng Guan, Wen Xia

Published online on: August 23, 2019
Open Access

miR‑488 negatively regulates osteogenic differentiation of bone marrow mesenchymal stem cells induced by psoralen by targeting Runx2

Yongquan Huang, Qiuke Hou, Haitao Su, Dongfeng Chen, Yiwen Luo, Tao Jiang

Published online on: August 23, 2019
Open Access

Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives

Dimitris Tsoukalas, Persefoni Fragkiadaki, Anca Oana Docea, Athanasios K. Alegakis, Evangelia Sarandi, Maria Thanasoula, Demetrios A. Spandidos, Aristidis Tsatsakis, Mayya Petrovna Razgonova, Daniela Calina

Published online on: August 23, 2019
Open Access

Silencing of MALAT1 inhibits migration and invasion by sponging miR‑1‑3p in prostate cancer cells

Xiaofan Dai, Zuowen Liang, Lingyun Liu, Kaimin Guo, Shengqi Xu, Hongliang Wang

Published online on: August 22, 2019
Open Access

Crosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases

Taís Silveira Assmann, Fermín I. Milagro, José Alfredo Martínez

Published online on: August 21, 2019
Open Access

Synergistic effect of STAT3‑targeted small interfering RNA and AZD0530 against glioblastoma in vitro and in vivo

Qingjun Liu, Leibo Wang, David Li, Jingxia Zhao, Shen Chen, Jialin Li

Published online on: August 21, 2019
Open Access

Silencing Smad4 attenuates sensitivity of colorectal cancer cells to cetuximab by promoting epithelial‑mesenchymal transition

Zhenlv Lin, Lin Zhang, Junfeng Zhou, Jiantao Zheng

Published online on: August 21, 2019
Open Access

COX‑2 promotes epithelial‑mesenchymal transition and migration in osteosarcoma MG‑63 cells via PI3K/AKT/NF‑κB signaling

Xueliang Zhang, Peng Qu, Hui Zhao, Tong Zhao, Nong Cao

Published online on: August 21, 2019

Intracarotid cold saline infusion contributes to neuroprotection in MCAO‑induced ischemic stroke in rats via serum and glucocorticoid‑regulated kinase 1

Dazhi Wang, Zhi Huang, Lei Li, Yingnan Yuan, Lei Xiang, Xiaowen Wu, Caifang Ni, Wenfeng Yu

Published online on: August 21, 2019

MicroRNA‑373 exerts anti‑tumor functions in human liver cancer by targeting Rab22a

Ying Ye, Lijun Zhang, Yanan Song, Juhua Zhuang, Guoyu Wang, Jing Ni, Suiliang Zhang, Wei Xia

Published online on: August 21, 2019
Open Access

Sam68 mediates high glucose‑induced podocyte apoptosis through modulation of Bax/Bcl‑2

Yuyu Chen, Li Zhang, Shuangxin Liu, Binfeng Yao, Hong Zhang, Shun Liang, Jianchao Ma, Xinling Liang, Wei Shi

Published online on: August 21, 2019
Open Access

Accumulation of advanced glycation end products potentiate human retinal capillary endothelial cells mediated diabetic retinopathy

Dan Tao, Ninghua Ni, Tiesong Zhang, Chao Li, Qing Sun, Ling Wang, Yan Mei

Published online on: August 20, 2019

Overexpression of the medium‑conductance calcium‑activated potassium channel (SK4) and the HCN2 channel to generate a biological pacemaker

Hongyi Zhao, Mei Yang, Fengyuan Wang, Ankang Yang, Qingyan Zhao, Xi Wang, Yanhong Tang, Teng Wang, Congxin Huang

Published online on: August 20, 2019
Open Access

Strontium‑containing α‑calcium sulfate hemihydrate promotes bone repair via the TGF‑β/Smad signaling pathway

Zhi Liu, Zewei Yu, Hong Chang, Yu Wang, Haibo Xiang, Xianrong Zhang, Bin Yu

Published online on: August 20, 2019

Yeast extract inhibits the proliferation of renal cell carcinoma cells via regulation of iron metabolism

Daeun Moon, Jinu Kim, Sang‑Pil Yoon

Published online on: August 20, 2019
Open Access

Identification of key miRNA‑mRNA pairs in septic mice by bioinformatics analysis

Jianxin Chen, Min Lin, Sen Zhang

Published online on: August 20, 2019
Open Access

Impaired intestinal barrier function in a mouse model of hyperuricemia

Yingjie Guo, Hailong Li, Zhen Liu, Changgui Li, Yunqing Chen, Chen Jiang, Yanan Yu, Zibin Tian

Published online on: August 12, 2019
Open Access

MicroRNA‑451 relieves inflammation in cerebral ischemia‑reperfusion via the Toll‑like receptor 4/MyD88/NF‑κB signaling pathway

Wenyan Li, Minghao Dong, Liangzhao Chu, Luqian Feng, Xiaochuan Sun

Published online on: August 12, 2019
Open Access

SREBP2 is upregulated in esophageal squamous cell carcinoma and co‑operates with c‑Myc to regulate HMGCR expression

Chenxi Zhong, Limin Fan, Zhigang Li, Feng Yao, Heng Zhao

Published online on: August 9, 2019
Open Access

TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production

Chun Fan, Qiuxia Ji, Chunyang Zhang, Shuo Xu, Hui Sun, Zhiyuan Li

Published online on: August 9, 2019
Open Access

MicroRNA‑217 is involved in the progression of atherosclerosis through regulating inflammatory responses by targeting sirtuin 1

Liyun Zhang, Juan Chen, Qin He, Ze Chao, Xuyong Li, Manhua Chen

Published online on: August 9, 2019

Ameliorating effect of Citrus aurantium extracts and nobiletin on β‑amyloid (1‑42)‑induced memory impairment in mice

Hae Jin Lee, Sung‑Kwon Lee, Dong‑Ryung Lee, Bong‑Keun Choi, Bao Le, Seung Hwan Yang

Published online on: August 9, 2019
Open Access

Upregulation of Myc promotes the evasion of NK cell‑mediated immunity through suppression of NKG2D ligands in K562 cells

Young‑Shin Lee, Woong Heo, Cheol‑Hun Son, Chi‑Dug Kang, You‑Soo Park, Jaeho Bae

Published online on: August 9, 2019
Open Access

Krüppel‑like factor 4 ameliorates diabetic kidney disease by activating autophagy via the mTOR pathway

Jianguang Gong, Huifang Zhan, Yiwen Li, Wei Zhang, Juan Jin, Qiang He

Published online on: August 9, 2019

Inhibition of HDAC6 expression decreases brain injury induced by APOE4 and Aβ co‑aggregation in rats

Yuexia Ding, Airong Kang, Qiling Tang, Ying Zhao

Published online on: August 8, 2019

Aberrant expression of miR‑130a‑3p in ankylosing spondylitis and its role in regulating T‑cell survival

Fengju Li, Dingran Si, Xuejun Guo, Ningru Guo, Dandan Li, Liujing Zhang, Xianan Jian, Jiasheng Ma

Published online on: August 8, 2019

HIF‑1α promotes NLRP3 inflammasome activation in bleomycin‑induced acute lung injury

Jun‑Jun Huang, Jie Xia, Li‑Li Huang, Ya‑Chun Li

Published online on: August 8, 2019

Role of prostaglandin E2 receptor 4 in the modulation of apoptosis and mitophagy during ischemia/reperfusion injury in the kidney

Chenguang Ding, Feng Han, Heli Xiang, Yuxiang Wang, Meng Dou, Xinxin Xia, Yang Li, Jin Zheng, Xiaoming Ding, Wujun Xue, Puxun Tian

Published online on: August 8, 2019
Open Access

Role of osteoprotegerin in the regulation of dental epithelial‑mesenchymal signaling during tooth development

Xin Gao, Junming Zheng, Shaoqin Tu, Bin Cai, Rongsheng Zeng, Lusai Xiang

Published online on: August 7, 2019
Open Access

lncRNA/circRNA‑miRNA‑mRNA ceRNA network in lumbar intervertebral disc degeneration

Jinwen Zhu, Xinliang Zhang, Wenjie Gao, Huimin Hu, Xiaodong Wang, Dingjun Hao

Published online on: August 7, 2019
Open Access

PPWD1 is associated with the occurrence of postmenopausal osteoporosis as determined by weighted gene co‑expression network analysis

Guo‑Feng Qian, Lu‑Shun Yuan, Min Chen, Dan Ye, Guo‑Ping Chen, Zhe Zhang, Cheng‑Jiang Li, Vijith Vijayan, Yu Xiao

Published online on: August 7, 2019
Open Access

Berberine ameliorates CCl4‑induced liver injury in rats through regulation of the Nrf2‑Keap1‑ARE and p53 signaling pathways

Chun‑Yang Han, Tao‑Tao Sun, Guang‑Pei Xv, Si‑Si Wang, Jin‑Gang Gu, Cui‑Yan Liu

Published online on: August 6, 2019
Open Access

Effect of estradiol on high glucose‑induced osteoblast injury

Guangrun Li, Xiaofeng Jiang, Liping Liu, Xiaoyang Liu, Hongtao Liu, Zuofu Zhang

Published online on: August 6, 2019
Open Access

Impact of SLC20A1 on the Wnt/β‑catenin signaling pathway in somatotroph adenomas

Jianhua Li, Wei Dong, Zhenye Li, Hongyun Wang, Hua Gao, Yazhuo Zhang

Published online on: August 6, 2019
Open Access

Targeting heterotopic ossification by inhibiting activin receptor‑like kinase 2 function (Review)

Fuli Shi, Jiayu Gao, Junrong Zou, Ying Ying, Hui Lin

Published online on: August 6, 2019
Open Access

Niacin regulates apolipoprotein M expression via liver X receptor‑α

Liu Yang, Tie Li, Shuiping Zhao, Saidan Zhang

Published online on: August 6, 2019
Open Access

Multi‑organ assessment via a 9.4‑Tesla MRS evaluation of metabolites during the embryonic development of cleft palate induced by dexamethasone

Yue Xing, Wancong Zhang, Hanxing Zhao, Zhiwei Shen, Weijie Liang, Jianda Zhou, Lungang Shi, Jiasheng Chen, Xiaoping Zhong, Shijie Tang

Published online on: August 6, 2019
Open Access

Effect of chondrocyte mitochondrial dysfunction on cartilage degeneration: A possible pathway for osteoarthritis pathology at the subcellular level

Heng Liu, Zhuoyang Li, Yongping Cao, Yunpeng Cui, Xin Yang, Zhichao Meng, Rui Wang

Published online on: August 6, 2019
Open Access

Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma mouse model

So‑Hyeon Bok, Ji‑Hye Seo, Chun‑Sik Bae, Bossng Kang, Seung Sik Cho, Dae‑Hun Park

Published online on: August 6, 2019

Ulinastatin ameliorates LPS‑induced pulmonary inflammation and injury by blocking the MAPK/NF‑κB signaling pathways in rats

Minjie Ju, Hongyu He, Song Chen, Yimei Liu, Yujing Liu, Simeng Pan, Yijun Zheng, Lizhen Xuan, Duming Zhu, Zhe Luo

Published online on: August 6, 2019
Open Access

Upregulated microRNA‑671‑3p promotes tumor progression by suppressing forkhead box P2 expression in non‑small‑cell lung cancer

Zhi‑Ying Li, Zi‑Zhou Zhang, Hui Bi, Qiu‑Di Zhang, Su‑Juan Zhang, Lin Zhou, Xiao‑Qin Zhu, Jun Zhou

Published online on: August 6, 2019

RAD18 contributes to the migration and invasion of human cervical cancer cells via the interleukin‑1β pathway

Pengrong Lou, Shitao Zou, Zengfu Shang, Chao He, Aidi Gao, Shunyu Hou, Jundong Zhou

Published online on: August 6, 2019

Inhibition of microRNA‑124‑3p protects against acute myocardial infarction by suppressing the apoptosis of cardiomyocytes

Guangrong Hu, Lingbo Ma, Fei Dong, Xiao Hu, Sida Liu, Hui Sun

Published online on: August 6, 2019
Open Access

Cisplatin decreases cyclin D2 expression via upregulating miR‑93 to inhibit lung adenocarcinoma cell growth

Ning Xie, Yuan‑Rong Liu, Yan‑Mei Li, Ya‑Nan Yang, Li Pan, Yu‑Bo Wei, Ping‑Yu Wang, You‑Jie Li, Shu‑Yang Xie

Published online on: August 6, 2019
Open Access

Expression profile of tRNA‑derived fragments and their potential roles in human varicose veins

Chong Yu, Xiang Wang, Yi Hong, Guojun Chen, Jin  Ge, Hao Cao, Bin Zhou

Published online on: August 1, 2019

MicroRNA‑330 is downregulated in retinoblastoma and suppresses cell viability and invasion by directly targeting ROCK1

Ling Wang, Lina Wang, Lin Li, Hong Zhang, Xueman Lyu

Published online on: August 1, 2019
Open Access

Proapoptotic effects of 2,5‑hexanedione on pheochromocytoma cells via oxidative injury

Baoning Qi, Shouzhu Xu, Yuan Liang, Jiaxin Wang, Zhigang Zhang, Juan Li, Jing Zhou

Published online on: August 1, 2019
Open Access

Curcumin protects the pancreas from acute pancreatitis via the mitogen‑activated protein kinase signaling pathway

Yingjie Wang, Chanyuan Bu, Kangkang Wu, Rui Wang, Jiayong Wang

Published online on: August 1, 2019
Open Access

COL12A1, a novel potential prognostic factor and therapeutic target in gastric cancer

Xiaoxia Jiang, Mengjie Wu, Xin Xu, Liwei Zhang, Yingying Huang, Zhenzhen Xu, Kuifeng He, Haiyong Wang, Haohao Wang, Lisong Teng

Published online on: August 1, 2019
Open Access

Hepatic NPC1L1 overexpression attenuates alcoholic autophagy in mice

Youlin Wang, Pan Yang, Bo Zhang, Yao Ding, Shun  Lei, Yuning Hou, Xiaoqing Guan, Qingwang Li

Published online on: August 1, 2019

CaMKII mediates myocardial ischemia/reperfusion injury‑induced contracture in isolated rat heart

Ling‑Heng Kong, Feng‑Mei Xiong, Xing‑Li Su, Na Sun, Jing‑Jun Zhou, Jun Yu

Published online on: August 1, 2019
Open Access

Homoharringtonine enhances the effect of imatinib on chronic myelogenous leukemia cells by downregulating ZFX

Jingjing Wu, Bin Wei, Yuye Shi, Xueying Lu, Yihan Ding, Chunling Wang, Yufeng Li

Published online on: July 31, 2019
Open Access

Lentiviral‑mediated Shh reverses the adverse effects of high glucose on osteoblast function and promotes bone formation via Sonic hedgehog signaling

Zhu‑Ling Jiang, Han Jin, Zhong‑Shuang Liu, Ming‑Yue Liu, Xiao‑Fang Cao, Yang‑Yang Jiang, Hong‑Dan Bai, Bin Zhang, Ying Li

Published online on: July 31, 2019
Open Access

Identification of key genes in osteosarcoma by meta‑analysis of gene expression microarray

Junkui Sun, Hongen Xu, Muge Qi, Chi Zhang, Jianxiang Shi

Published online on: July 31, 2019
Open Access

Therapeutic effect of transplantation of human bone marrow‑derived mesenchymal stem cells on neuron regeneration in a rat model of middle cerebral artery occlusion

Ping Xie, Ming Deng, Qin‑Guo Sun, Yong‑Gang Ma, Yan Zhou, Jiang‑Hua Ming, Qing Chen, Shi‑Qing Liu, Jun‑Qi Liu, Jun Cai, Fei Wu

Published online on: July 30, 2019
Open Access

An 8‑gene signature predicts the prognosis of cervical cancer following radiotherapy

Fei Xie, Dan Dong, Na Du, Liang Guo, Weihua Ni, Hongyan Yuan, Nannan Zhang, Jiang Jie, Guomu Liu, Guixiang Tai

Published online on: July 29, 2019
Journal Cover

Print ISSN: 1791-2997
Online ISSN: 1791-3004

Sign up for eToc alerts

Recommend to Library

Full Size Image