Early Online

Downregulation of microRNA‑30a in bronchoalveolar lavage fluid from idiopathic pulmonary fibrosis patients

Bao Liu, Tingshu Jiang, Xingang Hu, Zhida Liu, Liming Zhao, Hongmei Liu, Zhaihua Liu, Lijun Ma

Published online on: October 18, 2018
Open Access

Identification of recurrent and novel mutations by whole‑genome sequencing of colorectal tumors from the Han population in Shanghai, eastern China

Hongfei Teng, Renyuan Gao, Nan Qin, Xun Jiang, Min Ren, Yu Wang, Shouxin Wu, Ning Li, Jiangman Zhao, Huanlong Qin

Published online on: October 17, 2018
Open Access

Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/β‑catenin pathway

Shaohua Zeng, Baoyi Zhu, Jun Zeng, Wenqi Wu, Chonghe Jiang

Published online on: October 17, 2018
Open Access

Lentiviral‑mediated inducible silencing of TLR4 attenuates neuropathic pain in a rat model of chronic constriction injury

Yantao Liu, Yan Zhang, Ruirui Pan, Mo Chen, Xiaoqiang Wang, Erliang Kong, Weifeng Yu, Yuming Sun, Feixiang Wu

Published online on: October 16, 2018
Open Access

Therapeutic effects of a mesenchymal stem cell‑based insulin‑like growth factor‑1/enhanced green fluorescent protein dual gene sorting system in a myocardial infarction rat model

Subin Jung, Jung‑Hyun Kim, Changwhi Yim, Minhyung Lee, Hyo Jin Kang, Donghoon Choi

Published online on: October 16, 2018
Open Access

High LIN28A and PLK4 co‑expression is associated with poor prognosis in epithelial ovarian cancer

Yao He, Hui Wang, Meina Yan, Xinxin Yang, Rong Shen, Xiaoge Ni, Xiaokun Chen, Peifang Yang, Miao Chen, Xiaodong Lu, Genbao Shao, Xiaoming Zhou, Qixiang Shao

Published online on: October 16, 2018
Open Access

Knockdown of the Hippo transducer YAP reduces proliferation and promotes apoptosis in the Jurkat leukemia cell

Ran Wu, Hui Yang, Jiangbo Wan, Xiaohui Deng, Linjun Chen, Siguo Hao, Liyuan Ma

Published online on: October 15, 2018

Helicobacter pylori infection enhances heparanase leading to cell proliferation via mitogen‑activated protein kinase signalling in human gastric cancer cells

Liping Liu, Yongxun Zhao, Guangrui Fan, Tiankui Shuai, Bin Li, Yumin Li

Published online on: October 15, 2018

EP4 knockdown alleviates glomerulosclerosis through Smad and MAPK pathways in mesangial cells

Yingjie Cao, Tianyi Pan, Xiaolan Chen, Jianhua Wu, Naifeng Guo, Bicheng Wang

Published online on: October 12, 2018

CXCL12 modulates the radiosensitivity of cervical cancer by regulating CD44

Zhichao Fu, Pei Zhang, Huachun Luo, Huijuan Huang, Fengmei Wang

Published online on: October 12, 2018
Open Access

[Corrigendum] High glucose promotes tumor cell proliferation and migration in lung adenocarcinoma via the RAGE‑NOXs pathway

Yuan‑Fan Liao, Sui Yin, Zi‑Qi Chen, Fan Li, Bo Zhao

Published online on: October 12, 2018
Open Access

The possible association between AQP9 in the intestinal epithelium and acute liver injury‑induced intestinal epithelium damage

Tianxin Xiang, Shanfei Ge, Jiangxiong Wen, Junfeng Xie, Lixia Yang, Xiaoping Wu, Na Cheng

Published online on: October 10, 2018
Open Access

Upregulated miR‑203a‑3p and its potential molecular mechanism in breast cancer: A study based on bioinformatics analyses and a comprehensive meta‑analysis

Kai‑Teng Cai, Cai‑Xia Feng, Jin‑Che Zhao, Rong‑Quan He, Jie Ma, Jin‑Cai Zhong

Published online on: October 10, 2018
Open Access

Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation

Zhengxin Huang, Yingfeng Liu, Xianping Huang

Published online on: October 10, 2018

Role of JNK signalling pathway and platelet‑lymphocyte aggregates in myocardial ischemia‑reperfusion injury and the cardioprotective effect of ischemic postconditioning in rats

Faxin Ren, Nan Mu, Mingxiao Gao, Jing Sun, Chuanhuan Zhang, Xiaojian Sun, Liudong Li, Jun Li, Tong Liu, Gary Tse, Mei Dong

Published online on: October 10, 2018
Open Access

Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease

Jinrong Fu, Jinjing Zou, Cheng Chen, Hongying Li, Lei Wang, Yanli Zhou

Published online on: October 10, 2018
Open Access

Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro

Ganming Deng, Kaiqun Li, Siwei Chen, Peisheng Chen, Haonan Zheng, Bin Yu, Kairui Zhang

Published online on: October 10, 2018

Biomarkers associated with binaprofen‑induced liver injury

Qiuping Guo, Jianmin Guo, Guiying Chen, Zhong Han, Baiquan Xiao, Ruomin Jin, Chun Liang, Wei Yang

Published online on: October 10, 2018

Long non‑coding RNA CASC2 inhibits progression and predicts favorable prognosis in epithelial ovarian cancer

Zhuowei Xue, Xiaolu Zhu, Yincheng Teng

Published online on: October 10, 2018
Open Access

Mining the potential therapeutic targets for coronary artery disease by bioinformatics analysis

Wendong Wang, Zhiwei Xu, Xiaobo Zhu, Xiaotong Chang

Published online on: October 10, 2018

MicroRNA‑339‑5p inhibits cell proliferation of acute myeloid leukaemia by directly targeting SOX4

Xueming Sun, Huaqiang Liu, Tingting Li, Laiying Qin

Published online on: October 10, 2018
Open Access

miR‑3666 suppresses cellular proliferation and invasion in colorectal cancer by targeting SATB2

Daqing Yang, Rizeng Li, Jianfu Xia, Wencai Li, Hong Zhou

Published online on: October 9, 2018

Effects of polymorphic DNA genes involved in BER and caspase pathways on the clinical outcome of myeloproliferative neoplasms under treatment with hydroxyurea

Ana P. Azevedo, Susana N. Silva, Alice Reichert, Fernando Lima, Esmeraldina Júnior, José Rueff

Published online on: October 8, 2018

Synergistic effects of vemurafenib and fingolimod (FTY720) in vemurafenib‑resistant melanoma cell lines

Tomoko Takahashi, Naoko Abe, Hiroyuki Kanoh, Yoshiko Banno, Mariko Seishima

Published online on: October 8, 2018

Lutein protects human retinal pigment epithelial cells from oxidative stress‑induced cellular senescence

Seon Yeong Chae, Sun Young Park, Geuntae Park

Published online on: October 8, 2018

An effective range of polydeoxyribonucleotides is critical for wound healing quality

Kyu‑Hee Hwang, Ji‑Hee Kim, Eun Young Park, Seung‑Kuy Cha

Published online on: October 8, 2018
Open Access

Microarray analysis reveals long non‑coding RNA SOX2OT as a novel candidate regulator in diabetic nephropathy

Xiaoxue Zhang, Jin Shang, Xiaoyang Wang, Genyang Cheng, Yumin Jiang, Dong Liu, Jing Xiao, Zhanzheng Zhao

Published online on: October 4, 2018

NF‑κB inhibitor DHMEQ inhibits titanium dioxide nanoparticle‑induced interleukin‑1β production: Inhibition of the PM2.5‑induced inflammation model

Hitomi Fukatsu, Naoki Koide, Saeko Tada‑Oikawa, Kiyora Izuoka, Akihiko Ikegami, Sahoko Ichihara, Tamami Ukaji, Naoko Morita, Yoshikazu Naiki, Takayuki Komatsu, Kazuo Umezawa

Published online on: October 3, 2018

Suppressing cell growth and inducing apoptosis by inhibiting miR‑23a‑5p in human bladder cancer

Yifan Li, Jing Quan, Xiang Pan, Jingcheng Zhou, Anbang He, Yongqing Lai, Guangchen Zhou

Published online on: October 2, 2018

Whole exome sequencing identification of a novel insertion mutation in the phospholipase C ε‑1 gene in a family with steroid resistant inherited nephrotic syndrome

Jamil Amjad Hashmi, Ramziah Ahmed Safar, Sibtain Afzal, Alia M. Albalawi, Feroz Abdu‑Samad, Zafar Iqbal, Sulman Basit

Published online on: October 2, 2018

Mangiferin: An effective therapeutic agent against several disorders (Review)

Suya Du, Huirong Liu, Tiantian Lei, Xiaofang Xie, Hailian Wang, Xia He, Rongsheng Tong, Yi Wang

Published online on: October 2, 2018
Open Access

Compound pathogenic mutation in the USH2A gene in Chinese RP families detected by whole‑exome sequencing

Yue‑Chuan Fu, Na Chen, Zi‑Long Qiu, Lin Liu, Jie Shen

Published online on: October 2, 2018
Open Access

Ketamine destabilizes growth of dendritic spines in developing hippocampal neurons in vitro via a Rho‑dependent mechanism

Sufang Jiang, Zimiao Hao, Xuze Li, Lijun Bo, Rui Zhang, Ying Wang, Xiaofeng Duan, Rongtian Kang, Lining Huang

Published online on: October 2, 2018
Open Access

MrgX2‑mediated internalization of LL‑37 and degranulation of human LAD2 mast cells

Taisuke Murakami, Kaori Suzuki, Francois Niyonsaba, Hiroyuki Tada, Johannes Reich, Hiroshi Tamura, Isao Nagaoka

Published online on: October 2, 2018
Open Access

Co-existence of endometriosis with 13 non-gynecological co-morbidities: Mutation analysis by whole exome sequencing

Charoula Matalliotaki, Michail Matalliotakis, Maria I. Zervou, Alexandra Trivli, Ioannis Matalliotakis, George Mavromatidis, Demetrios A. Spandidos, Hans M. Albertsen, Rakesh Chettier, Kenneth Ward, George N. Goulielmos

Published online on: October 1, 2018
Open Access

S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling

Lifan Zhu, Zhen Weng, Pengcheng Shen, Jianxin Zhou, Jincai Zeng, Fengbiao Weng, Xiaojian Zhang, Huilin Yang

Published online on: October 1, 2018

MicroRNA‑944 targets vascular endothelial growth factor to inhibit cell proliferation and invasion in osteosarcoma

Tingzhen Yan, Shiyong Zhu, Jing Zhang, Gongbiao Lu, Chaoliang Lv, Yanchun Wei, Minghua Luo

Published online on: October 1, 2018

Salmonella‑induced miR‑155 enhances necroptotic death in macrophage cells via targeting RIP1/3

Young‑Tae Ro, Guk‑Heui Jo, Sun‑Ah Jung, Eunjoo H. Lee, Jongdae Shin, Joon H. Lee

Published online on: October 1, 2018
Open Access

Profiling cytochrome P450 family 4 gene expression in human hepatocellular carcinoma

Hyuk Soo Eun, Sang Yeon Cho, Byung Seok Lee, In‑Ock Seong, Kyung‑Hee Kim

Published online on: October 1, 2018
Open Access

Peripheral artery disease and osteoporosis: Not only age‑related (Review)

Agostino Gaudio, Anastasia Xourafa, Rosario Rapisarda, Pietro Castellino , Salvatore Santo Signorelli

Published online on: September 27, 2018

Role of endothelin‑1 and its receptors in cerebral vasospasm following subarachnoid hemorrhage

Ya‑Wen Cheng, Wen‑Juan Li, Xiang‑Jun Dou, Rui Jia, Hua Yang, Xin‑Guang Liu, Cang‑Bao Xu, Jing Liu, Yong‑Xiao Cao, Guo‑Gang Luo

Published online on: September 27, 2018
Open Access

miR‑127 aggravates myocardial failure by promoting the TGF‑β1/Smad3 signaling

Hainian Xu, Fengmei Li

Published online on: September 27, 2018
Open Access

Characteristics of Nur77 and its ligands as potential anticancer compounds (Review)

Lingjuan Wu, Liqun Chen

Published online on: September 27, 2018

Identification of miRNA and mRNA expression profiles by PCR microarray in hepatitis B virus‑associated hepatocellular carcinoma

Xiong‑Wei Cui, Zhi‑Ling Qian, Cong Li, Shi‑Chang Cui

Published online on: September 27, 2018

Aloe emodin suppresses EGF‑induced neoplastic cell transformation by inhibiting the ERK/MSK1 and AKT/GSK3β signaling pathways

Juan Zhang, Lihua Guo, Quanwu Zhang, Kangdong Liu, Ziming Dong

Published online on: September 27, 2018

miR‑124 inhibits cell growth through targeting IQGAP1 in colorectal cancer

Jianyu Fan, Wenjing Zhang, Yanting Wu, Ping Wan, Qiang Guo, Yu Zhang

Published online on: September 27, 2018
Open Access

Oral microbial flora of patients with Sicca syndrome

Shuang Zhou, Ye Cai, Min Wang, Wei‑Dong Yang, Ning Duan

Published online on: September 27, 2018
Open Access

Knockdown of BRCC3 exerts an anti‑tumor effect on cervical cancer in vitro

Feifang Zhang, Qun Zhou

Published online on: September 26, 2018
Open Access

Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo

Hucheng Chen, Jiyu Xu, Yuan Lv, Ping He, Chunyan Liu, Jie Jiao, Shiwei Li, Xuhua Mao, Xue Xue

Published online on: September 25, 2018

LncRNA‑p21 promotes chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR‑451

Luping Tang, Jianbo Ding, Guangju Zhou, Zhihai Liu

Published online on: September 24, 2018
Open Access

Mechanism of HN‑3 cell apoptosis induced by carboplatin: Combination of mitochondrial pathway associated with Ca2+ and the nucleus pathways

Bo Shen, Wenjing Mao, Jin‑Chul Ahn, Phil‑Sang Chung, Peijie He

Published online on: September 24, 2018
Open Access

Berberine promotes nerve regeneration through IGFR‑mediated JNK‑AKT signal pathway

Hai‑Na Zhang, Ya‑Juan Sun, Huai‑Qiang He, Hong‑Yan Li, Qiu‑Li Xue, Zhong‑Min Liu, Guang‑Meng Xu, Li‑Hua Dong

Published online on: September 24, 2018
Open Access

Intermittent fasting increases SOD2 and catalase immunoreactivities in the hippocampus but does not protect from neuronal death following transient ischemia in gerbils

Ji Hyeon Ahn, Yoohun Noh, Bich Na Shin, Sung‑Su Kim, Joon Ha Park, Tae‑Kyeong Lee, Minah Song, Hyunjung Kim, Jae‑Chul Lee, Jun‑Hwan Yong, Il Jun Kang, Yun Lyul Lee, Moo‑Ho Won, Jong Dai Kim

Published online on: September 21, 2018
Open Access

Expression of long non‑coding RNA and mRNA in the hippocampus of mice with type 2 diabetes

Li‑Ya Ci, De‑Shan Liu, Jing‑Qing Yang, Yu Zhao Liu, Chang Ling Li, Xi Zhang, Chun Mei Ma, Rui Ting Hu

Published online on: September 21, 2018

Endoplasmic reticulum stress associated apoptosis as a novel mechanism in indoxyl sulfate‑induced cardiomyocyte toxicity

Xiao Tan, Xue‑Sen Cao, Pan Zhang, Fang‑Fang Xiang, Jie Teng, Jian‑Zhou Zou, Xiao‑Qiang Ding

Published online on: September 20, 2018
Open Access

Electroacupuncture inhibits sodium nitroprusside‑mediated chondrocyte apoptosis through the mitochondrial pathway

Jie Lin, Guangwen Wu, Jun Chen, Changlong Fu, Xiue Hong, Li Li, Xianxiang Liu, Mingxia Wu

Published online on: September 20, 2018
Open Access

A family with hypothyroidism caused by fatty acid synthase and apolipoprotein B receptor mutations

Jianhua Sun, Lizhi Sun, Weijie Chen, Xiao Yin, Yong Lu, Qiang Jiang

Published online on: September 20, 2018

ROR1 is highly expressed in circulating tumor cells and promotes invasion of pancreatic cancer

Gui‑Li Xu, Jian Shen, Yun‑Hua Xu, Wan‑Sheng Wang, Cai‑Fang Ni

Published online on: September 20, 2018
Open Access

Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord

Jing Li, Shi‑Qing Xu, Yu‑Ming Zhao, Shi Yu, Li‑Hong Ge, Bao‑Hua Xu

Published online on: September 20, 2018

Astragalus root induces ovarian β‑oxidation and suppresses estrogen‑dependent uterine proliferation

Banzragchgarav Orkhon, Kyoko Kobayashi, Batkhuu Javzan, Kenroh Sasaki

Published online on: September 19, 2018
Open Access

Examining the key genes and pathways in hepatocellular carcinoma development from hepatitis B virus‑positive cirrhosis

Qi‑Feng Chen, Jin‑Guo Xia, Wang Li, Lu‑Jun Shen, Tao Huang, Peihong Wu

Published online on: September 19, 2018
Journal Cover

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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