Early Online

Open Access

Src inhibition induces melanogenesis in human G361 cells

Kyung‑Eun Ku, Nahyun Choi, Sang‑Ho Oh, Won‑Serk Kim, Wonhee Suh, Jong‑Hyuk Sung

Published online on: February 15, 2019
Open Access

Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis

Suning Chen, Mao Sun, Xianghui Zhao, Zhifu Yang, Wenxing Liu, Jinyi Cao, Yi Qiao, Xiaoxing Luo, Aidong Wen

Published online on: February 15, 2019
Open Access

Protective effect of troxerutin and cerebroprotein hydrolysate injection on cerebral ischemia through inhibition of oxidative stress and promotion of angiogenesis in rats

Wenbing Ma, Shixiang Wang, Xuanlin Liu, Fengru Tang, Peipei Zhao, Kai Cheng, Qiaowei Zheng, Yingchen Zhuo, Xue Zhao, Xueqian Li, Weiyi Feng

Published online on: February 15, 2019
Open Access

Identification of key genes and pathways contributing to artery tertiary lymphoid organ development in advanced mouse atherosclerosis

Xi Zhang, Fayuan Liu, Peng Bai, Nianguo Dong, Chong Chu

Published online on: February 15, 2019

Repulsive guidance molecule a suppresses seizures and mossy fiber sprouting via the FAK‑p120RasGAP‑Ras signaling pathway

Mingyu Song, Fafa Tian, Huang Xia, Yuanyuan Xie

Published online on: February 14, 2019
Open Access

Overexpression of microRNA‑101 causes anti‑tumor effects by targeting CREB1 in colon cancer

Qinglin Yang, Weijie Yu, Xiaoli Han

Published online on: February 14, 2019
Open Access

Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus

Yu‑Han Qi, Rui Zhu, Qing Wang, Qian Li, Yi‑Dan Liu, Zhong‑Yi Qian, Zhi‑Hong Yang, Zhi‑Hao Mu, Xin‑Jie Liu, Mei‑Yan Zhang, Xie Wang, Xin‑Yu Liao, Qi Wan, Di Lu, Ying‑Ying Zou

Published online on: February 14, 2019
Open Access

Rab7‑mediated autophagy regulates phenotypic transformation and behavior of smooth muscle cells via the Ras/Raf/MEK/ERK signaling pathway in human aortic dissection

Keshuai He, Haoliang Sun, Junjie Zhang, Rui Zheng, Jiaxi Gu, Ming Luo, Yongfeng Shao

Published online on: February 14, 2019

MicroRNA‑466 inhibits cell proliferation and invasion in osteosarcoma by directly targeting insulin receptor substrate 1

Yongning Sun, Jingzhen Zhou, Lina Shi, Jie Li, Jianming Chen

Published online on: February 14, 2019
Open Access

Age‑ and brain region‑associated alterations of cerebral blood flow in early Alzheimer's disease assessed in AβPPSWE/PS1ΔE9 transgenic mice using arterial spin labeling

Yapei Guo, Xueyuan Li, Min Zhang, Ningning Chen, Shitao Wu, Jianfeng Lei, Zhanjing Wang, Renzhi Wang, Jianping Wang, Hengfang Liu

Published online on: February 12, 2019
Open Access

Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of patients with head and neck cancer

Vahinipriya Manoharan, Eric Hamilton Karunanayake, Kamani Hemamala Tennekoon, Sumadee De Silva, Kanishka De Silva, Preethika Angunawela, John Lunec

Published online on: February 11, 2019
Open Access

Prognostic significance of deregulated microRNAs in uveal melanomas

Luca Falzone, Giovanni L. Romano, Rossella Salemi, Claudio Bucolo, Barbara Tomasello, Gabriella Lupo, Carmelina D. Anfuso, Demetrios A. Spandidos, Massimo Libra, Saverio Candido

Published online on: February 11, 2019

Liraglutide protects renal mesangial cells against hyperglycemia‑mediated mitochondrial apoptosis by activating the ERK‑Yap signaling pathway and upregulating Sirt3 expression

Jian Li, Nan Li, Shuangtong Yan, Yanhui Lu, Xinyu Miao, Zhaoyan Gu, Yinghong Shao

Published online on: February 8, 2019
Open Access

Resveratrol alleviates hypoxia/reoxygenation injury‑induced mitochondrial oxidative stress in cardiomyocytes

Tao Li, Linlin Chen, Yiyan Yu, Binbin Yang, Pengyun Li, Xiao‑Qiu Tan

Published online on: February 7, 2019
Open Access

Expression of autophagy‑associated proteins in rat dental irreversible pulpitis

Shengcai Qi, Jun Qian, Fubo Chen, Peng Zhou, Jing Yue, Fengqin Tang, Yiming Zhang, Shiqiang Gong, Guangwei Shang, Chun Cui, Yuanzhi Xu

Published online on: February 7, 2019
Open Access

Pioglitazone increases VEGFR3 expression and promotes activation of M2 macrophages via the peroxisome proliferator‑activated receptor γ

Conghui Zhang, Ying Zhang, Chunxiu Zhang, Yang Liu, Yanyan Liu, Gang Xu

Published online on: February 7, 2019

Deletion of Dicer blocks osteogenic differentiation via the inhibition of Wnt signalling

Hong‑Yan Wu, Rui Bi, Ting Sun, Fei Xie

Published online on: February 6, 2019
Open Access

[Corrigendum] IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer

Yidi Guo, Ying Zang, Lianzheng Lv, Feng Cai, Tingting Qian, Guoying Zhang, Quancheng Feng

Published online on: February 6, 2019
Open Access

Comprehensive bioinformatics analysis of critical lncRNAs, mRNAs and miRNAs in non‑alcoholic fatty liver disease

Huiling Wu, Xi Song, Yuntao Ling, Jin Zhou, Zhen Tao, Yuying Shen

Published online on: February 5, 2019
Open Access

Differences in the distribution of CD20, CD3, CD34 and CD45RO in nasal mucosa and polyps from patients with chronic rhinosinusitis

Mihaela Mitroi, Dana Albulescu, Alina Capitanescu, Anca Oana Docea, Gabriela Musat, George Mitroi, Ovidiu Zlatian, Aristidis Tsatsakis, George Tzanakakis, Demetrios A. Spandidos, Daniela Calina

Published online on: February 5, 2019
Open Access

Implantation of engineered conduction tissue in the rat heart

Wenbo Zhang, Xiaotong Li, Shanquan Sun, Xi Zhang

Published online on: February 5, 2019

MicroRNA‑663b targets GAB2 to restrict cell proliferation and invasion in hepatocellular carcinoma

Liping Guo, Baoli Li, Meijing Miao, Jianjun Yang, Jinshan Ji

Published online on: February 5, 2019
Open Access

Comprehensive circular RNA expression profiles in a mouse model of nonalcoholic steatohepatitis

Qiang Ou, Yajuan Zhao, Jianhua Zhou, Xiaolin Wu

Published online on: February 5, 2019

Puerarin alters the function of monocytes/macrophages and exhibits chondroprotection in mice

Libo Peng, Zikang Xie, Jie Pei, Bing Wang, Yi Gao, Yuxing Qu

Published online on: February 5, 2019
Open Access

RNA sequencing discloses the genome‑wide profile of long noncoding RNAs in dilated cardiomyopathy

Guangyong Huang, Jingwen Liu, Chuansheng Yang, Youzhang Xiang, Yuehai Wang, Jing Wang, Miaomiao Cao, Wenbo Yang

Published online on: February 5, 2019
Open Access

Construction of a cDNA library and preliminary analysis of the expressed sequence tags of the earthworm Eisenia fetida (Savigny, 1826)

Chang Liu, Xuan Wang, Jiu‑Bo Tian, Pei‑Yuan Ma, Fan‑Xiu Meng, Qi Zhang, Bao‑Feng Yu, Rui Guo, Zhi‑Zhen Liu, Hai‑Long Wang, Jun Xie, Niu‑Liang Cheng, Jian‑Hua Wang, Bo Niu, Gong‑Qin Sun

Published online on: February 5, 2019
Open Access

Establishment and evaluation of a simulated high‑altitude hypoxic brain injury model in SD rats

Ya Hou, Xiaobo Wang, Xiaorui Chen, Jing Zhang, Xiaopeng Ai, Yusheng Liang, Yangyang Yu, Yi Zhang, Xianli Meng, Tingting Kuang, Yao Hu

Published online on: February 5, 2019
Open Access

Oxidized unsaturated fatty acids induce apoptotic cell death in cultured cells

Katsuya Iuchi, Mika Ema, Moe Suzuki, Chikako Yokoyama, Hisashi Hisatomi

Published online on: February 5, 2019
Open Access

Prediction and analysis of weighted genes in hepatocellular carcinoma using bioinformatics analysis

Qifan Zhang, Shibo Sun, Chen Zhu, Yujian Zheng, Qing Cai, Xiaolu Liang, Haorong Xie, Jie Zhou

Published online on: February 4, 2019
Open Access

Comparison of adipose‑ and bone marrow‑derived stem cells in protecting against ox‑LDL‑induced inflammation in M1‑macrophage‑derived foam cells

Jian‑Zhong Li, Tian‑Hui Cao, Jin‑Cheng Han, Hui Qu, Shuang‑Quan Jiang, Bao‑Dong Xie, Xiao‑Long Yan, Hua Wu, Xiang‑Lan Liu, Fan Zhang, Xiao‑Ping Leng, Kai Kang, Shu‑Lin Jiang

Published online on: February 1, 2019

MicroRNA‑504 targets AEG‑1 and inhibits cell proliferation and invasion in retinoblastoma

Lina Wang, Xueman Lyu, Yunqing Ma, Fei Wu, Ling Wang

Published online on: February 1, 2019
Open Access

Fluoxetine induces direct inhibitory effects on mesenchymal stem cell‑derived osteoprogenitor cells independent of serotonin concentration

Samar M. Koura, Mohamed Salama, Mahmoud El‑Hussiny, Mahmoud El‑Sayed Awad Khalil, Ahmed Lotfy, Samia Ahmed Hassan, Seham Aly Gad Elhak, Mohamed A. Sobh

Published online on: February 1, 2019
Open Access

[Retracted] Pathogenetic mechanism of lipoid proteinosis caused by mutation of the extracellular matrix protein 1 gene

Dong Gao, Xianying Ma, Peiwen Lian, Surong Zhou, Jian Chen

Published online on: February 1, 2019
Open Access

Aberrant expression of sperm‑specific glycolytic enzymes are associated with poor sperm quality

Xuexia Liu, Qian Li, Wenjuan Wang, Fujun Liu

Published online on: February 1, 2019
Open Access

10‑Hydroxycamptothecin induces apoptosis in human fibroblasts by regulating miRNA‑23b‑3p expression

Lingrong Zeng, Yu Sun, Xiaolei Li, Jingcheng Wang, Lianqi Yan

Published online on: February 1, 2019
Open Access

Tetramethylpyrazine reduces inflammation in the livers of mice fed a high fat diet

Bing Chen, Yaluan Ma, Xin Xue, Jie Wei, Gang Hu, Yajun Lin

Published online on: February 1, 2019
Open Access

miR‑155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia

Xiao‑Hua Sun, Ming‑Fen Song, Hai‑Dong Song, Yu‑Wen Wang, Ming‑Jin Luo, Li‑Ming Yin

Published online on: January 31, 2019
Open Access

NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats

Lin Chen, Ping‑Lin He, Jin Yang, Ya‑Fei Yang, Kai Wang, Bastian Amend, Arnulf Stenzl, Ya‑Mei Zhang, Zi‑Li Wang, Sha‑Sha Xing, Xu Luo

Published online on: January 31, 2019
Open Access

Colonic M1 macrophage is associated with the prolongation of gastrointestinal motility and obesity in mice treated with vancomycin

Yoshihito Inoue, Hirokazu Fukui, Xin Xu, Ying Ran, Toshihiko Tomita, Tadayuki Oshima, Jiro Watari, Hiroto Miwa

Published online on: January 31, 2019
Open Access

Identification of a pathogenic mutation in a Chinese pedigree with polycystic kidney disease

Kexian Dong, Huanhuan Miao, Xueyuan Jia, Jie Wu, Han Wu, Jiawei Sun, Wei Ji, Hui Su, Lidan Xu, Xuelong Zhang, Siqi Zhu, Guohua Ji, Rongwei Guan, Hao Wang, Jing Bai, Jingcui Yu, Wenjing Sun, Xianli Zhou, Songbin Fu

Published online on: January 31, 2019
Open Access

Rhynchophylline ameliorates myocardial ischemia/reperfusion injury through the modulation of mitochondrial mechanisms to mediate myocardial apoptosis

Qiao‑Ji Qin, Li‑Qiang Cui, Peng Li, Yong‑Bin Wang, Xue‑Zhi Zhang, Ming‑Lei Guo

Published online on: January 30, 2019

Inflammatory and fibrosis infiltration in synovium associated with the progression in developmental dysplasia of the hip

De Li, Hui Wang, Ji‑Ye He, Cheng‑Long Wang, Wei‑Jia Feng, Chao Shen, Jun‑Feng Zhu, Dong‑Liang Wang, Xiao‑Dong Chen

Published online on: January 30, 2019
Open Access

Potential urine biomarkers for gestational hypertension and preeclampsia

Hong‑Xia Guo, Yan‑Bin Zhu, Cui‑Ping Wu, Mei Zhong, Shui‑Wang Hu

Published online on: January 30, 2019
Open Access

Investigating age‑induced differentially expressed genes and potential molecular mechanisms in osteosarcoma based on integrated bioinformatics analysis

Jian‑Sheng Wang, Ming‑Yue Duan, Yong‑Sheng Zhong, Xue‑Dong Li, Shi‑Xin Du, Peng Xie, Gui‑Zhou Zheng, Jing‑Ming Han

Published online on: January 30, 2019

Preliminary study on the role of miR‑148a and DNMT1 in the pathogenesis of acute myeloid leukemia

Xiao‑Xue Wang, Heyang Zhang, Yan Li

Published online on: January 30, 2019

Functional genetic variants of the GATA4 gene promoter in acute myocardial infarction

Jing Chen, Shuai Wang, Shuchao Pang, Yinghua Cui, Bo Yan, Robert G. Hawley

Published online on: January 30, 2019

Regulation of Fgf15 expression in the intestine by glucocorticoid receptor

Kunzhi Jia, Danping Zhang, Qi Jia, Qing‑Yu Zhang

Published online on: January 30, 2019
Open Access

Ketamine‑induced bladder dysfunction is associated with extracellular matrix accumulation and impairment of calcium signaling in a mouse model

Cheng‑Huang Shen, Shou‑Tsung Wang, Shou‑Chieh Wang, Shu‑Mei Lin, Lei‑Chen Lin, Yuan‑Chang Dai, Yi‑Wen Liu

Published online on: January 29, 2019

The anthelmintic agent oxfendazole inhibits cell growth in non‑small cell lung cancer by suppressing c‑Src activation

Dafu Xu, Wenze Tian, Chao Jiang, Ziming Huang, Shiying Zheng

Published online on: January 28, 2019
Open Access

Upregulation of ADAMTS‑7 and downregulation of COMP are associated with spontaneous abortion

Yang Mu, Dan‑Ni Zhou, Na‑Na Yan, Jin‑Li Ding, Jing Yang

Published online on: January 28, 2019
Open Access

Effects of varying radiation dosages on MMP1 expression, and MMP1 knockdown on the viability and migration of SW620 cells

Fang Ju, Na Li, Wenming Wang, Haicheng Yuan

Published online on: January 28, 2019

Knockdown of ARK5 expression suppresses invasion of ovarian cancer cells

Shuxiao Wang, Shuwei Li, Hui Wang, Wei Li, Yuxue Gao, Xuejian Wang, Chunyan Fang, Baogang Zhang, Xiuning Sun, Ruifang Li, Weiwei Shi, Meiling Chen, Lihong Shi

Published online on: January 28, 2019
Open Access

Integrative analysis of cancer driver genes in prostate adenocarcinoma

Xin Zhao, Yi Lei, Ge Li, Yong Cheng, Haifan Yang, Libo Xie, Hao Long, Rui Jiang

Published online on: January 28, 2019
Open Access

Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain

Sheng Li, Chao Sun, Yu Gu, Xing Gao, Yuanlin Zhao, Yuan Yuan, Feng Zhang, Peizhen Hu, Weihua Liang, Kaiyu Cao, Jin Zhang, Zhe Wang, Jing Ye

Published online on: January 28, 2019
Open Access

MicroRNA‑124 improves functional recovery and suppresses Bax‑dependent apoptosis in rats following spinal cord injury

Zhongyang Xu, Kefeng Zhang, Qian Wang, Yanping Zheng

Published online on: January 28, 2019
Open Access

circRNA‑miRNA association for coronary heart disease

Fei Lin, Guoan Zhao, Zhigang Chen, Xuehui Wang, Fenghua Lv, Yongchun Zhang, Xiaodong Yang, Wanqian Liang, Ruiyan Cai, Jianhua Li, Meng Li, Guhao Zhang

Published online on: January 28, 2019

Long non‑coding RNA DANCR promotes nasopharyngeal carcinoma cell proliferation and migration

Yalin Hao, Hui Zhao, Xiaojie Jin, Ping He, Jiafeng Zhang, Qiongna Dong, Weiwei Shi, Miaomiao Zhao

Published online on: January 28, 2019

Long noncoding RNA homeobox A11 antisense promotes transforming growth factor β1‑induced fibrogenesis in cardiac fibroblasts

Jiangting Wang, Xiaowei Liu, Qin Zhuang, Rongrong Pan, Linlin Zou, Zhenbo Cen, Lijiang Tang

Published online on: January 24, 2019
Open Access

BP‑1‑102 exerts an antitumor effect on the AGS human gastric cancer cell line through modulating the STAT3 and MAPK signaling pathways

Xiaoxia Jiang, Jian Tang, Mengjie Wu, Shitu Chen, Zhenzhen Xu, Haiyong Wang, Haohao Wang, Xiongfei Yu, Zhongqi Li, Lisong Teng

Published online on: January 24, 2019

Expression and role of TNIP2 in multiple organ dysfunction syndrome following severe trauma

Hui Gong, Xiaomin Sheng, Jianhua Xue, Dongbo Zhu

Published online on: January 24, 2019

Profiling lncRNA alterations during TNF‑α induced osteogenic differentiation of dental pulp stem cells

Ran Tao, Yu‑Xi Li, Ya‑Ke Liu, Fan Liu, Zhen‑Yu Zhou

Published online on: January 24, 2019

Insulin‑like growth factor I promotes adipogenesis in hemangioma stem cells from infantile hemangiomas

Fan Wang, Honghong Li, Yin Lou, Juan Xie, Dongsheng Cao, Xueying Huang

Published online on: January 24, 2019

Simultaneous detection of target CNVs and SNVs of thalassemia by multiplex PCR and next‑generation sequencing

Dong‑Mei Fan, Xu Yang, Li‑Min Huang, Guo‑Jun Ouyang, Xue‑Xi Yang, Ming Li

Published online on: January 24, 2019
Journal Cover

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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