Open Access

Genetics and epigenetics of melanoma (Review)

Retraction in: /10.3892/ol.2020.12045

  • Authors:
    • Xiao-Ying Zhang
    • Pei-Ying Zhang
  • View Affiliations

  • Published online on: September 5, 2016     https://doi.org/10.3892/ol.2016.5093
  • Pages: 3041-3044
  • Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-induced genetic aberrations that stimulate skin melanocytes to develop unlimited growth. This eventually leads to cell immortality, which in turn causes metastases. The present review examines the genetics and epigenetics of this pathological state together with recent perspectives of the therapeutic management of disease.
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November-2016
Volume 12 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhang X and Zhang X: Genetics and epigenetics of melanoma (Review) Retraction in /10.3892/ol.2020.12045. Oncol Lett 12: 3041-3044, 2016
APA
Zhang, X., & Zhang, X. (2016). Genetics and epigenetics of melanoma (Review) Retraction in /10.3892/ol.2020.12045. Oncology Letters, 12, 3041-3044. https://doi.org/10.3892/ol.2016.5093
MLA
Zhang, X., Zhang, P."Genetics and epigenetics of melanoma (Review) Retraction in /10.3892/ol.2020.12045". Oncology Letters 12.5 (2016): 3041-3044.
Chicago
Zhang, X., Zhang, P."Genetics and epigenetics of melanoma (Review) Retraction in /10.3892/ol.2020.12045". Oncology Letters 12, no. 5 (2016): 3041-3044. https://doi.org/10.3892/ol.2016.5093