1
|
Vaupel P, Schlenger K, Knoop C and Höckel
M: Oxygenation of human tumors: Evaluation of tissue oxygen
distribution in breast cancers by computerized O2 tension
measurements. Cancer Res. 51:3316–3322. 1991.PubMed/NCBI
|
2
|
Vaupel P: The role of hypoxia-induced
factors in tumor progression. Oncologist. 9:(Suppl 5). S10–S17.
2004. View Article : Google Scholar
|
3
|
Fisher ER, Anderson S, Redmond C and
Fisher B: Pathologic findings from the national surgical adjuvant
breast project protocol B-06. 10-year pathologic and clinical
prognostic discriminants. Cancer. 71:2507–2514. 1993. View Article : Google Scholar : PubMed/NCBI
|
4
|
Hockel M and Vaupel P: Tumor hypoxia:
Definitions and current clinical, biologic, and molecular aspects.
J Natl Cancer Inst. 93:266–276. 2001. View Article : Google Scholar : PubMed/NCBI
|
5
|
Garcia S, Dalès JP, Charafe-Jauffret E,
Carpentier-Meunier S, Andrac-Meyer L, Jacquemier J, Andonian C,
Lavaut MN, Allasia C, Bonnier P and Charpin C: Poor prognosis in
breast carcinomas correlates with increased expression of
targetable CD146 and c-Met and with proteomic basal-like phenotype.
Hum Pathol. 38:830–841. 2007. View Article : Google Scholar : PubMed/NCBI
|
6
|
Kallergi G, Markomanolaki H, Giannoukaraki
V, Papadaki MA, Strati A, Lianidou ES, Georgoulias V, Mavroudis D
and Agelaki S: Hypoxia-inducible factor-1alpha and vascular
endothelial growth factor expression in circulating tumor cells of
breast cancer patients. Breast cancer Res. 11:R842009. View Article : Google Scholar : PubMed/NCBI
|
7
|
Karlin KL, Mondal G, Hartman JK, Tyagi S,
Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, et
al: The oncogenic STP axis promotes triple-negative breast cancer
via degradation of the REST tumor suppressor. Cell Rep.
9:1318–1332. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Gleadle JM and Ratcliffe PJ: Induction of
hypoxia-inducible factor-1, erythropoietin, vascular endothelial
growth factor, and glucose transporter-1 by hypoxia: Evidence
against a regulatory role for Src kinase. Blood. 89:503–509.
1997.PubMed/NCBI
|
9
|
Price BD and Calderwood SK: Gadd45 and
Gadd153 messenger RNA levels are increased during hypoxia and after
exposure of cells to agents which elevate the levels of the
glucose-regulated proteins. Cancer Res. 52:3814–3817.
1992.PubMed/NCBI
|
10
|
Moulder JE and Rockwell S: Tumor hypoxia:
Its impact on cancer therapy. Cancer Metastasis Rev. 5:313–341.
1987. View Article : Google Scholar : PubMed/NCBI
|
11
|
Giaccia AJ: Hypoxic stress proteins:
Survival of the Fittest. Semin Radiat Oncol. 6:46–58. 1996.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Kunz M and Ibrahim SM: Molecular responses
to hypoxia in tumor cells. Mol Cancer. 2:232003. View Article : Google Scholar : PubMed/NCBI
|
13
|
Harris AL: Hypoxia-a key regulatory factor
in tumour growth. Nat Rev Cancer. 2:38–47. 2002. View Article : Google Scholar : PubMed/NCBI
|
14
|
Semenza GL: HIF-1, O(2), and the 3 PHDs:
How animal cells signal hypoxia to the nucleus. Cell. 107:1–3.
2001. View Article : Google Scholar : PubMed/NCBI
|
15
|
Jaakkola P, Mole DR, Tian YM, Wilson MI,
Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji
M, Schofield CJ, et al: Targeting of HIF-alpha to the von
Hippel-Lindau ubiquitylation complex by O2-regulated prolyl
hydroxylation. Science. 292:468–472. 2001. View Article : Google Scholar : PubMed/NCBI
|
16
|
Semenza GL: Hypoxia, clonal selection, and
the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol.
35:71–103. 2000. View Article : Google Scholar : PubMed/NCBI
|
17
|
Kreike B, van Kouwenhove M, Horlings H,
Weigelt B, Peterse H, Bartelink H and van de Vijver MJ: Gene
expression profiling and histopathological characterization of
triple-negative/basal-like breast carcinomas. Breast Cancer Res.
9:R652007. View
Article : Google Scholar : PubMed/NCBI
|
18
|
Rakha EA, Elsheikh SE, Aleskandarany MA,
Habashi HO, Green AR, Powe DG, El-Sayed ME, Benhasouna A, Brunet
JS, Akslen LA, et al: Triple-negative breast cancer: Distinguishing
between basal and nonbasal subtypes. Clin Cancer Res. 15:2302–2310.
2009. View Article : Google Scholar : PubMed/NCBI
|
19
|
Tan EY, Yan M, Campo L, Han C, Takano E,
Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, et al: The
key hypoxia regulated gene CAIX is upregulated in basal-like breast
tumours and is associated with resistance to chemotherapy. Br J
Cancer. 100:405–411. 2009. View Article : Google Scholar : PubMed/NCBI
|
20
|
Tsuda H, Takarabe T, Hasegawa F, Fukutomi
T and Hirohashi S: Large, central acellular zones indicating
myoepithelial tumor differentiation in high-grade invasive ductal
carcinomas as markers of predisposition to lung and brain
metastases. Am J Surg Pathol. 24:197–202. 2000. View Article : Google Scholar : PubMed/NCBI
|
21
|
Riva C, Chauvin C, Pison C and Leverve X:
Cellular physiology and molecular events in hypoxia-induced
apoptosis. Anticancer Res. 18:4729–4736. 1998.PubMed/NCBI
|
22
|
Vaupel P, Kallinowski F and Okunieff P:
Blood flow, oxygen and nutrient supply, and metabolic
microenvironment of human tumors: A review. Cancer Res.
49:6449–6465. 1989.PubMed/NCBI
|
23
|
Semenza GL, Roth PH, Fang HM and Wang GL:
Transcriptional regulation of genes encoding glycolytic enzymes by
hypoxia-inducible factor 1. J Biol Chem. 269:23757–23763.
1994.PubMed/NCBI
|
24
|
Mizunuma H and Tashima Y:
Fructose-1,6-biphosphatase of the small intestine. Purification and
comparison with liver and muscle fructose-1,6-bisphosphatases. J
Biochem. 84:327–336. 1978. View Article : Google Scholar : PubMed/NCBI
|
25
|
Tillmann H and Eschrich K: Isolation and
characterization of an allelic cDNA for human muscle
fructose-1,6-bisphosphatase. Gene. 212:295–304. 1998. View Article : Google Scholar : PubMed/NCBI
|
26
|
Tejwani GA: Regulation of
fructose-bisphosphatase activity. Adv Enzymol Relat Areas Mol Biol.
54:121–194. 1983.PubMed/NCBI
|
27
|
Liu X, Wang X, Zhang J, Lam EK, Shin VY,
Cheng AS, Yu J, Chan FK, Sung JJ and Jin HC: Warburg effect
revisited: An epigenetic link between glycolysis and gastric
carcinogenesis. Oncogene. 29:442–450. 2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Li B, Qiu B, Lee DS, Walton ZE, Ochocki
JD, Mathew LK, Mancuso A, Gade TP, Keith B, Nissim I and Simon MC:
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Nature. 513:251–255. 2014. View Article : Google Scholar : PubMed/NCBI
|
29
|
Bigl M, Jandrig B, Horn LC and Eschrich K:
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase
genes in cancer. Biochem Biophys Res Commun. 377:720–724. 2008.
View Article : Google Scholar : PubMed/NCBI
|
30
|
Viale G: Histopathology of primary breast
cancer 2003. Breast. 12:391–396. 2003. View Article : Google Scholar : PubMed/NCBI
|
31
|
Elston CW and Ellis IO: Pathological
prognostic factors in breast cancer. I. The value of histological
grade in breast cancer: Experience from a large study with
long-term follow-up. Histopathology. 41:154–161. 2002.PubMed/NCBI
|
32
|
Carlson RW: NCCN breast cancer clinical
practice guidelines in oncology: An update. J Natl Compr Canc Netw.
1:(Suppl 1). S61–S63. 2003.PubMed/NCBI
|
33
|
Zhou M, Zhao Y, Ding Y, Liu H, Liu Z,
Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, et al: Warburg
effect in chemosensitivity: Targeting lactate dehydrogenase-A
re-sensitizes taxol-resistant cancer cells to taxol. Mol Cancer.
9:332010. View Article : Google Scholar : PubMed/NCBI
|
34
|
Bos R, van der Groep P, Greijer AE,
Shvarts A, Meijer S, Pinedo HM, Semenza GL, van Diest PJ and van
der Wall E: Levels of hypoxia-inducible factor-1alpha independently
predict prognosis in patients with lymph node negative breast
carcinoma. Cancer. 97:1573–1581. 2003. View Article : Google Scholar : PubMed/NCBI
|
35
|
Jacobs TW, Gown AM, Yaziji H, Barnes MJ
and Schnitt SJ: Specificity of HercepTest in determining HER-2/neu
status of breast cancers using the United States Food and Drug
Administration-approved scoring system. J Clin Oncol. 17:1983–1987.
1999. View Article : Google Scholar : PubMed/NCBI
|
36
|
Livasy CA, Karaca G, Nanda R, Tretiakova
MS, Olopade OI, Moore DT and Perou CM: Phenotypic evaluation of the
basal-like subtype of invasive breast carcinoma. Mod Pathol.
19:264–271. 2006. View Article : Google Scholar : PubMed/NCBI
|
37
|
Nielsen TO, Hsu FD, Jensen K, Cheang M,
Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler
L, et al: Immunohistochemical and clinical characterization of the
basal-like subtype of invasive breast carcinoma. Clin Cancer Res.
10:5367–5374. 2004. View Article : Google Scholar : PubMed/NCBI
|
38
|
Yamamoto Y, Ibusuki M, Okumura Y, Kawasoe
T, Kai K, Iyama K and Iwase H: Hypoxia-inducible factor 1alpha is
closely linked to an aggressive phenotype in breast cancer. Breast
Cancer Res Treat. 110:465–475. 2008. View Article : Google Scholar : PubMed/NCBI
|
39
|
Dales JP, Garcia S, Meunier-Carpentier S,
Andrac-Meyer L, Haddad O, Lavaut MN, Allasia C, Bonnier P and
Charpin C: Overexpression of hypoxia-inducible factor HIF-1alpha
predicts early relapse in breast cancer: Retrospective study in a
series of 745 patients. Int J Cancer. 116:734–739. 2005. View Article : Google Scholar : PubMed/NCBI
|
40
|
Schindl M, Schoppmann SF, Samonigg H,
Hausmaninger H, Kwasny W, Gnant M, Jakesz R, Kubista E, Birner P
and Oberhuber G: Austrian Breast and Colorectal Cancer Study Group:
Overexpression of hypoxia-inducible factor 1alpha is associated
with an unfavorable prognosis in lymph node-positive breast cancer.
Clin Cancer Res. 8:1831–1837. 2002.PubMed/NCBI
|
41
|
Giatromanolaki A, Koukourakis MI,
Simopoulos C, Polychronidis A, Gatter KC, Harris AL and Sivridis E:
c-erbB-2 related aggressiveness in breast cancer is hypoxia
inducible factor-1alpha dependent. Clin Cancer Res. 10:7972–7977.
2004. View Article : Google Scholar : PubMed/NCBI
|
42
|
Schoppmann SF, Fenzl A, Schindl M,
Bachleitner-Hofmann T, Nagy K, Gnant M, Horvat R, Jakesz R and
Birner P: Hypoxia inducible factor-1alpha correlates with VEGF-C
expression and lymphangiogenesis in breast cancer. Breast Cancer
Res Treat. 99:135–141. 2006. View Article : Google Scholar : PubMed/NCBI
|
43
|
Kronblad A, Jirstrom K, Rydén L,
Nordenskjöld B and Landberg G: Hypoxia inducible factor-1alpha is a
prognostic marker in premenopausal patients with intermediate to
highly differentiated breast cancer but not a predictive marker for
tamoxifen response. Int J Cancer. 118:2609–2616. 2006. View Article : Google Scholar : PubMed/NCBI
|
44
|
Semenza GL: HIF-1 and tumor progression:
Pathophysiology and therapeutics. Trends Mol Med. 8:(4 Suppl).
S62–S67. 2002. View Article : Google Scholar : PubMed/NCBI
|
45
|
Zhong H, De Marzo AM, Laughner E, Lim M,
Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL and Simons
JW: Overexpression of hypoxia-inducible factor 1alpha in common
human cancers and their metastases. Cancer Res. 59:5830–5835.
1999.PubMed/NCBI
|
46
|
Page EL, Robitaille GA, Pouysségur J and
Richard DE: Induction of hypoxia-inducible factor-1alpha by
transcriptional and translational mechanisms. J Biol Chem.
277:48403–48409. 2002. View Article : Google Scholar : PubMed/NCBI
|
47
|
Gizak A, Rakus D and Dzugaj A: Nuclear
localization of fructose 1,6-bisphosphatase in smooth muscle cells.
J Mol Histol. 36:243–248. 2005. View Article : Google Scholar : PubMed/NCBI
|
48
|
Mamczur P, Mazurek J and Rakus D:
Ubiquitous presence of gluconeogenic regulatory enzyme,
fructose-1,6-bisphosphatase, within layers of rat retina. Cell
Tissue Res. 341:213–221. 2010. View Article : Google Scholar : PubMed/NCBI
|
49
|
Nordlie RC, Foster JD and Lange AJ:
Regulation of glucose production by the liver. Annu Rev Nutr.
19:379–406. 1999. View Article : Google Scholar : PubMed/NCBI
|
50
|
Radziuk J and Pye S: Hepatic glucose
uptake, gluconeogenesis and the regulation of glycogen synthesis.
Diabetes Metab Res Rev. 17:250–272. 2001. View Article : Google Scholar : PubMed/NCBI
|
51
|
Bhide SV: Enzyme studies on tumour cell
suspensions. Br J Cancer. 24:869–874. 1970. View Article : Google Scholar : PubMed/NCBI
|
52
|
Pouysségur J, Dayan F and Mazure NM:
Hypoxia signalling in cancer and approaches to enforce tumour
regression. Nature. 441:437–443. 2006. View Article : Google Scholar : PubMed/NCBI
|
53
|
Ryan HE, Poloni M, McNulty W, Elson D,
Gassmann M, Arbeit JM and Johnson RS: Hypoxia-inducible
factor-1alpha is a positive factor in solid tumor growth. Cancer
Res. 60:4010–4015. 2000.PubMed/NCBI
|