1
|
Guo H, Wu F, Wang Y, Yan C and Su W:
Overexpressed ubiquitin ligase Cullin7 in breast cancer promotes
cell proliferation and invasion via down-regulating p53. Biochem
Biophys Res Commun. 450:1370–1376. 2014. View Article : Google Scholar : PubMed/NCBI
|
2
|
Keyaerts M, Xavier C, Heemskerk J,
Devoogdt N, Everaert H, Ackaert C, Vanhoeij M, Duhoux FP, Gevaert
T, Simon P, et al: Phase I study of 68Ga-HER2-Nanobody for PET/CT
assessment of HER2-expression in breast carcinoma. J Nucl Med.
57:27–33. 2016. View Article : Google Scholar : PubMed/NCBI
|
3
|
Al-Hussaini H, Subramanyam D, Reedijk M
and Sridhar SS: Notch signaling pathway as a therapeutic target in
breast cancer. Mol Cancer Ther. 10:9–15. 2011. View Article : Google Scholar : PubMed/NCBI
|
4
|
Yuan X, Zhang M, Wu H, Xu H, Han N, Chu Q,
Yu S, Chen Y and Wu K: Expression of Notch1 correlates with breast
cancer progression and prognosis. PLoS One. 10:e01316892015.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Roy M, Pear WS and Aster JC: The
multifaceted role of Notch in cancer. Curr Opin Genet Dev.
17:52–59. 2007. View Article : Google Scholar : PubMed/NCBI
|
6
|
Palmer WH and Deng WM: Ligand-independent
mechanisms of Notch activity. Trends Cell Biol. 25:697–707. 2015.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Artavanis-Tsakonas S, Rand MD and Lake RJ:
Notch signaling: Cell fate control and signal integration in
development. Science. 284:770–776. 1999. View Article : Google Scholar : PubMed/NCBI
|
8
|
Kopan R and Ilagan MX: The canonical Notch
signaling pathway: Unfolding the activation mechanism. Cell.
137:216–233. 2009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Radtke F and Raj K: The role of Notch in
tumorigenesis: Oncogene or tumour suppressor. Nat Rev Cancer.
3:756–767. 2003. View
Article : Google Scholar : PubMed/NCBI
|
10
|
Robinson DR, Kalyana-Sundaram S, Wu YM,
Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso
CS, et al: Functionally recurrent rearrangements of the MAST kinase
and Notch gene families in breast cancer. Nat Med. 17:1646–1651.
2011. View
Article : Google Scholar : PubMed/NCBI
|
11
|
Liao WR, Hsieh RH, Hsu KW, Wu MZ, Tseng
MJ, Mai RT, Wu Lee YH and Yeh TS: The CBF1-independent Notch1
signal pathway activates human c-myc expression partially via
transcription factor YY1. Carcinogenesis. 28:1867–1876. 2007.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Xia J, Li Y, Yang Q, Mei C, Chen Z, Bao B,
Ahmad A, Miele L, Sarkar FH and Wang Z: Arsenic trioxide inhibits
cell growth and induces apoptosis through inactivation of Notch
signaling pathway in breast cancer. In J Mol Sci. 13:9627–9641.
2012. View Article : Google Scholar
|
13
|
Rangarajan A, Talora C, Okuyama R, Nicolas
M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, et
al: Notch signaling is a direct determinant of keratinocyte growth
arrest and entry into differentiation. EMBO J. 20:3427–3436. 2001.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Ling H and Jolicoeur P: Notch-1 signaling
promotes the cyclinD1-dependent generation of mammary
tumor-initiating cells that can revert to bi-potential progenitors
from which they arise. Oncogene. 32:3410–3419. 2013. View Article : Google Scholar : PubMed/NCBI
|
15
|
Palomero TL, Lim WK, Odom DT, Sulis ML,
Real PJ, Margolin A, Barnes KC, O'Neil J, Neuberg D, Weng AP, et
al: Notch1 directly regulates c-MYC and activates a
feed-forward-loop transcriptional network promoting leukemic cell
growth. Proc Natl Acad Sci USA. 103:pp. 18261–18266. 2006;
View Article : Google Scholar : PubMed/NCBI
|
16
|
Ramdass B, Maliekal TT, Lakshmi S, Rehman
M, Rema P, Nair P, Mukherjee G, Reddy BK, Krishna S and
Radhakrishna Pillai M: Coexpression of Notch1 and NF-kappaB
signaling pathway components in human cervical cancer progression.
Gynecol Onco. 104:352–361. 2007. View Article : Google Scholar
|
17
|
Xie M, He CS, Wei SH and Zhang L: Notch-1
contributes to epidermal growth factor receptor tyrosine kinase
inhibitor acquired resistance in non-small cell lung cancer in
vitro and in vivo. Eur J Cancer. 49:3559–3572. 2013. View Article : Google Scholar : PubMed/NCBI
|
18
|
Sionov RV, Kfir-Erenfeld S, Spokoini R and
Yefenof E: A role for bcl-2 in Notch1-dependent transcription in
thymic lymphoma cells. Adv Hematol. 2012:4352412012. View Article : Google Scholar : PubMed/NCBI
|
19
|
Colgate EC, Miranda CL, Stevens JF, Bray
TM and Ho E: Xanthohumol, a prenylflavonoid derived from hops
induces apoptosis and inhibits NF-kappaB activation in prostate
epithelial cells. Cancer Lett. 246:201–209. 2007. View Article : Google Scholar : PubMed/NCBI
|
20
|
Gerhauser C, Alt A, Heiss E, Gamal-Eldeen
A, Klimo K, Knauft J, Neumann I, Scherf HR, Frank N, Bartsch H and
Becker H: Cancer chemopreventive activity of Xanthohumol, a natural
product derived from hop. Mol Cancer Ther. 1:959–969.
2002.PubMed/NCBI
|
21
|
Gonçalves P, Araújo JR, Pinho MJ and
Martel F: In vitro studies on the inhibition of colon cancer by
butyrate and polyphenolic compounds. Nutr Cancer. 63:282–294. 2011.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Nozawa H: Xanthohumol, the chalcone from
beer hops (Humulus lupulus L.), is the ligand for farnesoid X
receptor and ameliorates lipid and glucose metabolism in KK-A(y)
mice. Biochem Biophys Res Commun. 336:754–761. 2005. View Article : Google Scholar : PubMed/NCBI
|
23
|
Pan L, Becker H and Gerhäuser C:
Xanthohumol induces apoptosis in cultured 40–16 human colon cancer
cells by activation of the death receptor- and mitochondrial
pathway. Mol Nutr Food Res. 49:837–843. 2005. View Article : Google Scholar : PubMed/NCBI
|
24
|
Shi J, Chen J, Serradji N, Xu X, Zhou H,
Ma Y, Sun Z, Jiang P, Du Y, Yang J, et al: PMS1077 sensitizes TNF-α
induced apoptosis in human prostate cancer cells by blocking NF-κB
signaling pathway. PLoS One. 8:e611322013. View Article : Google Scholar : PubMed/NCBI
|
25
|
Liu P, Zhao L, Xu X, Liu F, Zhang W, Zhou
C, Chen J, Pan Y, Du Y, Yang J and Wang Q: N6-substituted adenosine
analogues, a novel class of JAK2 inhibitors, potently block STAT3
signaling in human cancer cells. Cancer Lett. 354:43–57. 2014.
View Article : Google Scholar : PubMed/NCBI
|
26
|
Zhang X, Samadi AK, Roby KF, Timmermann B
and Cohen MS: Inhibition of cell growth and induction of apoptosis
in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural
withanolide Withaferin A. Gynecol Oncol. 124:606–612. 2012.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Pei J and Wang B: Notch-1 promotes breast
cancer cells proliferation by regulating LncRNA GAS5. Int J Clin
Exp Med. 8:14464–14471. 2015.PubMed/NCBI
|
28
|
Farnie G and Clarke RB: Breast stem cells
and cancer. Ernst Schering Found Symp Proc. pp. 1–153. 2006;
|
29
|
Rasul S, Balasubramanian R, Filipović A,
Slade MJ, Yagüe E and Coombes RC: Inhibition of gamma-secretase
induces G2/M arrest and triggers apoptosis in breast cancer cells.
Br J Cancer. 100:1879–1888. 2009. View Article : Google Scholar : PubMed/NCBI
|
30
|
Shih IeM and Wang TL: Notch signaling,
gamma-secretase inhibitors and cancer therapy. Cancer Res.
67:1879–1882. 2007. View Article : Google Scholar : PubMed/NCBI
|
31
|
Beel AJ and Sanders CR: Substrate
specificity of gamma-secretase and other intramembrane proteases.
Cell Mol Life Sci. 65:1311–1334. 2008. View Article : Google Scholar : PubMed/NCBI
|
32
|
van Es JH, van Gijn ME, Riccio O, van den
Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ,
Radtke F and Clevers H: Notch/gamma-secretase inhibition turns
proliferative cells in intestinal crypts and adenomas into goblet
cells. Nature. 435:959–963. 2005. View Article : Google Scholar : PubMed/NCBI
|
33
|
Guerreiro S, Monteiro R, Martins MJ,
Calhau C, Azevedo I and Soares R: Distinct modulation of alkaline
phosphatase isoenzymes by 17beta-estradiol and xanthohumol in
breast cancer MCF-7 cells. Clin Biochem. 40:268–273. 2007.
View Article : Google Scholar : PubMed/NCBI
|
34
|
Mendes V, Monteiro R, Pestana D, Teixeira
D, Calhau C and Azevedo I: Xanthohumol influences preadipocyte
differentiation: Implication of antiproliferative and apoptotic
effects. J Agric Food Chem. 56:11631–11637. 2008. View Article : Google Scholar : PubMed/NCBI
|
35
|
Cho MY, Park SY, Park S, Lee YR, Han GD
and Kim JA: Geranyl derivative of phloroacetophenone induces cancer
cell-specific apoptosis through Bax-mediated mitochondrial pathway
in MCF-7 human breast cancer cells. Biol Pharm Bull. 35:98–104.
2012. View Article : Google Scholar : PubMed/NCBI
|
36
|
Hsieh CY, Tsai PC, Tseng CH, Chen YL,
Chang LS and Lin SR: Inhibition of EGF/EGFR activation with
naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of
MDA-MB-231 cells. Toxicol In Vitro. 27:1–10. 2013. View Article : Google Scholar : PubMed/NCBI
|
37
|
Dai J, Ma D, Zang S, Guo D, Qu X, Ye J and
Ji C: Cross-talk between Notch and EGFR signaling in human breast
cancer cells. Cancer Invest. 27:533–540. 2009. View Article : Google Scholar : PubMed/NCBI
|
38
|
Lange C, Huttner WB and Calegari F:
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1,
delays neurogenesis, and promotes the generation and expansion of
basal progenitors. Cel Stem Cell. 5:320–331. 2009. View Article : Google Scholar
|
39
|
Waga S, Hannon GJ, Beach D and Stillman B:
The p21 inhibitor of cyclin-dependent kinases controls DNA
replication by interaction with PCNA. Nature. 369:574–578. 1994.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Xiong Y, Hannon GJ, Zhang H, Casso D,
Kobayashi R and Beach D: p21 is a universal inhibitor of cyclin
kinases. Nature. 366:701–704. 1993. View Article : Google Scholar : PubMed/NCBI
|
41
|
Dowsett M, Nielsen TO, A'Hern R, Bartlett
J, Coombes RC, Cuzick J, Ellis M, Henry NL, Hugh JC, Lively T, et
al: Assessment of Ki67 in breast cancer: Recommendations from the
International Ki67 in Breast Cancer working group. J Natl Cancer
Inst. 103:1656–1664. 2011. View Article : Google Scholar : PubMed/NCBI
|
42
|
Basu S, Combe K, Kwiatkowski F,
Caldefie-Chézet F, Penault-Llorca F, Bignon YJ and Vasson MP:
Cellular expression of cyclooxygenase, aromatase, adipokines,
inflammation and cell proliferation markers in breast cancer
specimen. PLoS One. 10:e01384432015. View Article : Google Scholar : PubMed/NCBI
|