Open Access

IMRT dose verification considering passing rate and respiratory motion

  • Authors:
    • Kai Xie
    • Hongfei Sun
    • Tao Lin
    • Liugang Gao
    • Jianfeng Sui
    • Xinye Ni
  • View Affiliations

  • Published online on: May 16, 2018     https://doi.org/10.3892/ol.2018.8724
  • Pages: 963-969
  • Copyright: © Xie et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 4.0].

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Abstract

The aim of the present study was to investigate the association between the dynamic intensity‑modulated radiation therapy planned γ analysis passing rate and respiratory amplitude (A) and period (T) for different tumor volumes. A total of 30 patients with malignant lung tumors were divided into three groups: A; B; and C. The average tumor volumes (V) in the A, B and C groups were 635, 402 and 213 cm3, respectively. The simulated A values were set at 0, 5, 10, 15, 20 and 25 mm. The T values were set at 4, 5 and 6 sec. The γ analysis passing rate was calculated under different conditions (dose difference, 3%; distance difference, 3 mm). Compared with the γ analysis passing rate in the A group (A=0, static; T=4, 5, 6 sec), the γ analysis passing rate deviation (A=5 mm) was <3.3%. However, this difference was not statistically significant (P>0.05). With a gradual increase in A value, the passing rate decreased. The deviation between the 3 groups was <2.5% at the same A value (T=4, 5 and 6 sec). A descending trend of passing rate with increased A value was revealed. At the same A and T values, the passing rate decreased with decreased tumor volume. At the same tumor volume, the passing rate decreased when the A value increased. The respiratory cycle was not demonstrated to be associated with the passing rate. Overall, these results suggest that the A value should be controlled in clinical radiotherapy.
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July-2018
Volume 16 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Xie K, Sun H, Lin T, Gao L, Sui J and Ni X: IMRT dose verification considering passing rate and respiratory motion. Oncol Lett 16: 963-969, 2018
APA
Xie, K., Sun, H., Lin, T., Gao, L., Sui, J., & Ni, X. (2018). IMRT dose verification considering passing rate and respiratory motion. Oncology Letters, 16, 963-969. https://doi.org/10.3892/ol.2018.8724
MLA
Xie, K., Sun, H., Lin, T., Gao, L., Sui, J., Ni, X."IMRT dose verification considering passing rate and respiratory motion". Oncology Letters 16.1 (2018): 963-969.
Chicago
Xie, K., Sun, H., Lin, T., Gao, L., Sui, J., Ni, X."IMRT dose verification considering passing rate and respiratory motion". Oncology Letters 16, no. 1 (2018): 963-969. https://doi.org/10.3892/ol.2018.8724