Open Access

Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report

  • Authors:
    • Filippo Ricciardiello
    • Raffaele Addeo
    • Antonella Miriam Di Lullo
    • Teresa Abate
    • Salvatore Mazzone
    • Flavia Oliva
    • Giovanni Motta
    • Michelle Caraglia
    • Massimo Mesolella
  • View Affiliations

  • Published online on: June 18, 2018     https://doi.org/10.3892/ol.2018.8976
  • Pages: 2783-2788
  • Copyright: © Ricciardiello et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Adenoid cystic carcinoma (ACC) is a relatively rare tumor that accounts for <1% of all head and neck malignancies. Laryngeal localization of ACC, which is most commonly hypoglottic, is relatively rare, occurring in 0.07‑0.25% of all laryngeal tumors. ACC is characterized as a slow-growing tumor with a high recurrence rate, which often causes dyspnea and hoarseness. ACC exhibits a propensity for perineural invasion and thus, patients may experience pain as a late symptom of the disease. Distant metastasis occurs in 35-50% of cases and the lungs are the most common site of metastasis. Tumors are usually diagnosed by physical examination with fiberoscopy and computed tomography of the neck and chest, due to the high rate of lung metastases. The standard therapy for ACC is surgery followed by radiotherapy. In this study, a 70-year-old patient presented with laryngeal ACC, who underwent total laryngectomy with bilateral neck dissection and adjuvant radiotherapy, is presented. Follow‑up examination performed 2 years after surgery revealed no evidence of locoregional recurrence or distant metastases. Previously published literature regarding ACC of the larynx was also reviewed.
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September-2018
Volume 16 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Ricciardiello F, Addeo R, Di Lullo AM, Abate T, Mazzone S, Oliva F, Motta G, Caraglia M and Mesolella M: Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report. Oncol Lett 16: 2783-2788, 2018
APA
Ricciardiello, F., Addeo, R., Di Lullo, A.M., Abate, T., Mazzone, S., Oliva, F. ... Mesolella, M. (2018). Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report. Oncology Letters, 16, 2783-2788. https://doi.org/10.3892/ol.2018.8976
MLA
Ricciardiello, F., Addeo, R., Di Lullo, A. M., Abate, T., Mazzone, S., Oliva, F., Motta, G., Caraglia, M., Mesolella, M."Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report". Oncology Letters 16.3 (2018): 2783-2788.
Chicago
Ricciardiello, F., Addeo, R., Di Lullo, A. M., Abate, T., Mazzone, S., Oliva, F., Motta, G., Caraglia, M., Mesolella, M."Adenoid cystic carcinoma of the larynx in a 70-year-old patient: A case report". Oncology Letters 16, no. 3 (2018): 2783-2788. https://doi.org/10.3892/ol.2018.8976