Open Access

A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer

  • Authors:
    • Anjun Ma
    • Dianxia Fan
    • Fangli Yan
  • View Affiliations

  • Published online on: August 1, 2018     https://doi.org/10.3892/ol.2018.9250
  • Pages: 5186-5190
  • Copyright: © Ma et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the study was to investigate the application of tumor abnormal protein (TAP) combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer. A total of 248 patients with suspected endometrial cancer who were admitted to the Gynecology Department of the Second People's Hospital of Liaocheng from September 2013 to September 2015 were selected and randomly divided into the control (n=124) and the observation group (n=124). The control group received conventional ultrasound examination, while the observation, underwent TAP combined with conventional ultrasound examination. Differences in the definite diagnostic results of the two diagnostic methods and curettage were compared, and the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer was studied. Among 248 patients receiving hysteroscopy and diagnostic curettage examination, there were 75 patients with early-stage endometrial cancer, and 173 benign patients. The total diagnostic accordance rate of conventional ultrasound for endometrial lesions was 87.90% (n=218), and the accordance rate for early-stage endometrial carcinoma was 90.67% (n=68); the total diagnostic accordance rate of TAP combined with vaginal ultrasound for endometrial lesions was 94.35% (n=234), and for early-stage endometrial cancer was 94.67% (n=71); of TAP combined with conventional ultrasound for endometrial lesions and endometrial cancer were higher than those of simple conventional ultrasound (P<0.05). The area under the curve (AUC) of conventional ultrasound in the diagnosis of endometrial cancer was 0.754 [95% confidence interval (CI): 0.211-2.534]. The AUC of TAP combined with vaginal ultrasound in the diagnosis of endometrial cancer was 0.814 (95% CI: 0.517-0.932), and a comparison between the two groups was statistically significant (P=0.011). The accuracy rate of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer is relatively high, and it is worthy promoting and applying in clinical practice.
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October-2018
Volume 16 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Ma A, Fan D and Yan F: A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer. Oncol Lett 16: 5186-5190, 2018
APA
Ma, A., Fan, D., & Yan, F. (2018). A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer. Oncology Letters, 16, 5186-5190. https://doi.org/10.3892/ol.2018.9250
MLA
Ma, A., Fan, D., Yan, F."A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer". Oncology Letters 16.4 (2018): 5186-5190.
Chicago
Ma, A., Fan, D., Yan, F."A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer". Oncology Letters 16, no. 4 (2018): 5186-5190. https://doi.org/10.3892/ol.2018.9250