Open Access

Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy

  • Authors:
    • Ailan Xian
    • Chunbin Wang
    • Ni Guo
    • Zaixing Wang
    • Lei Yang
    • Jie Gao
    • Longjun Yang
  • View Affiliations

  • Published online on: December 6, 2018     https://doi.org/10.3892/ol.2018.9801
  • Pages: 1589-1594
  • Copyright: © Xian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Anesthetic effect of remifentanil combined with propofol in awakening painless endoscopy was analyzed. Retrospective analysis of 120 cases of colon cancer were treated in Dongying People's Hospital from June 2015 to December 2017. All of them were treated by awakening painless digestive endoscopy, divided into 60 cases in observation group (combined with remifentanil and propofol anesthesia), and 60 cases in control group (combined intravenous anesthesia of finanib and propofol). The data were respectively recorded at time‑points of oxygen inhalation, intubation for 10 min, awakening time, waking time, and the time‑points for each represented as the time‑points of T1, T2, T3, T4, T5 and recorded the diastolic blood pressure (DBP), respiratory rate (RR) and heart rate (HR), and compared the awakening effect and the occurrence of adverse reaction. There was no significant difference in the DBP index between the two groups at time‑point T1 (P>0.05). The time‑points of T2, T3, T4 and T5 were significantly different from the observation group (P<0.05). There was no significant difference in RR index between the two groups and between the same groups (P>0.05). Compared with the control group, the awakening time and consciousness recovering of the observation group is lower (P<0.05). The incidence of adverse reactions after awakening operation between the two groups was statistically significant (P<0.05). The local pain rate in the observation group after the awakening operation was lower than the control group. The combined use of trace remifentanil and small dose propofol in the awakening painless digestive endoscopy can make the patients with colon cancer more stable when they are in the awakening state, so as to improve the safety of awakening painless digestive endoscopy. It is worth promoting in clinical practice.
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February-2019
Volume 17 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Xian A, Wang C, Guo N, Wang Z, Yang L, Gao J and Yang L: Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy. Oncol Lett 17: 1589-1594, 2019
APA
Xian, A., Wang, C., Guo, N., Wang, Z., Yang, L., Gao, J., & Yang, L. (2019). Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy. Oncology Letters, 17, 1589-1594. https://doi.org/10.3892/ol.2018.9801
MLA
Xian, A., Wang, C., Guo, N., Wang, Z., Yang, L., Gao, J., Yang, L."Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy". Oncology Letters 17.2 (2019): 1589-1594.
Chicago
Xian, A., Wang, C., Guo, N., Wang, Z., Yang, L., Gao, J., Yang, L."Application of remifentanil combined with propofol in the diagnosis of colon cancer with awakening painless digestive endoscopy". Oncology Letters 17, no. 2 (2019): 1589-1594. https://doi.org/10.3892/ol.2018.9801