Analysis of risk factors for pulmonary infection in patients with minimally invasive esophagectomy

Liu,Guangyuan; Peng,Lin; Liu,Bin; Wang,Kangning; Han,Yongtao

doi:10.3892/ol.2019.9987

Analysis of risk factors for pulmonary infection in patients with minimally invasive esophagectomy

Authors:
- Guangyuan Liu
- Lin Peng
- Bin Liu
- Kangning Wang
- Yongtao Han
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Affiliations: Ward 1, Department of Thoracic Surgery, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan 610041, P.R. China, Clinical Research Standardized Treatment Ward, Department of Medical Oncology, Sichuan Cancer Hospital and Institute, Chengdu, Sichuan 610041, P.R. China
Published online on: January 29, 2019 https://doi.org/10.3892/ol.2019.9987
Pages: 3283-3288

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Abstract

Clinical manifestations of patients with pulmonary infection after minimally invasive esophagectomy were analyzed. A total of 500 patients undergoing minimally invasive esophagectomy in Sichuan Cancer Hospital and Institute from January 2015 to December 2016 were consecutively selected, among which 124 patients with pulmonary infection after surgery were taken as the infection group, and the remaining 376 patients were taken as the control group. The clinical data of all patients were collected. The pulmonary infection rate after minimally invasive esophagectomy was calculated, and clinical factors with difference were analyzed using the multivariate logistic regression analysis. There were significant differences in age, long-term smoking history, pre-sence or absence of concurrent basic diseases and vital capacity (P<0.01). The application time of antibiotics and antacids and hospitalization duration in the infection group were obviously longer than those in the control group (P<0.01). Age, long-term smoking history, vital capacity, application time of antibiotics and antacids, hospitalization duration and concurrent diabetes mellitus/coronary heart disease/diseases of respiratory system increase the risk of postoperative pulmonary infection in patients with esophageal cancer, and age, long-term smoking history, diabetes mellitus, diseases of respiratory system and hospitalization duration are independent risk factors for pulmonary infection in patients after minimally invasive esophagectomy.

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