Early Online

Open Access

Ganoderic acid A exerts antitumor activity against MDA‑MB‑231 human breast cancer cells by inhibiting the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway

Yuguang Yang, Hongfeng Zhou, Wenming Liu, Jin Wu, Xiaolong Yue, Jincai Wang, Lina Quan, Hang Liu, Li Guo, Zhipeng Wang, Xin Lian, Qingyuan Zhang

Published online on: September 21, 2018
Open Access

Low expression of miR‑199 in hepatocellular carcinoma contributes to tumor cell hyper‑proliferation by negatively suppressing XBP1

Zheng Lou, Yong‑Qiang Gong, Xing Zhou, Guo‑Huang Hu

Published online on: September 21, 2018

The effect of centromere protein U silencing by lentiviral mediated RNA interference on the proliferation and apoptosis of breast cancer

Shuang‑Yan Lin, Yan‑Bo Lv, Gen‑Xiang Mao, Xu‑Jiao Chen, Fang Peng

Published online on: September 21, 2018

Acidosis promotes cell apoptosis through the G protein‑coupled receptor 4/CCAAT/enhancer‑binding protein homologous protein pathway

Biao Dong, Xiaolu Zhang, Yafeng Fan, Songqiang Cao, Xuepei Zhang

Published online on: September 21, 2018

Evaluation of positive ductal margins of biliary tract cancer in intraoperative histological examination

Junji Ueda, Hiroshi Yoshida, Yasuhiro Mamada, Nobuhiko Taniai, Masato Yoshioka, Atsushi Hirakata, Youichi Kawano, Yoshiaki Mizuguchi, Tetsuya Shimizu, Tomohiro Kanda, Hideyuki Takata, Ryota Kondo, Eiji Uchida

Published online on: September 21, 2018
Open Access

MicroRNA‑140‑5p suppresses cell proliferation and invasion in gastric cancer by targeting WNT1 in the WNT/β‑catenin signaling pathway

Yinlian Cha, Ying He, Kaobin Ouyang, Hailin Xiong, Jun Li, Xia Yuan

Published online on: September 21, 2018
Open Access

Th17 response in patients with cervical cancer (Review)

Jayra Juliana Paiva Alves, Thales Allyrio Araújo de Medeiros Fernandes, Josélio Maria Galvão de Araújo, Ricardo Ney Oliveira Cobucci, Daniel Carlos Ferreira Lanza, Fabiana Lima Bezerra, Vânia Sousa Andrade, José Veríssimo Fernandes

Published online on: September 21, 2018

Effects of FOXM1 inhibition and ionizing radiation on melanoma cells

Vivienne S. Lee, Lucinda S. McRobb, Vaughan Moutrie, Estavam D. Santos, Timothy L. Siu

Published online on: September 21, 2018
Open Access

Aberrant expression of glycogen synthase kinase‑3β in human breast and head and neck cancer

Andrey V. Ugolkov, Maria Matsangou, Timothy J. Taxter, Thomas V. O'Halloran, Vincent L. Cryns, Francis J. Giles, Andrew P. Mazar

Published online on: September 21, 2018

Gene networks in basal cell carcinoma of the eyelid, analyzed using gene expression profiling

Tatsuya Yunoki, Yoshiaki Tabuchi, Tetsushi Hirano, Shigeharu Miwa, Johji Imura, Atsushi Hayashi

Published online on: September 21, 2018

Intervenolin suppresses gastric cancer cell growth through the induction of TSP‑1 secretion from fibroblast‑like stromal cells

Junjiro Yoshida, Hikaru Abe, Takumi Watanabe, Manabu Kawada

Published online on: September 21, 2018
Open Access

Serum levels of candidate microRNA diagnostic markers differ among the stages of non‑small‑cell lung cancer

Toshiko Aiso, Kouki Ohtsuka, Makiko Ueda, Shin Karita, Takuma Yokoyama, Saori Takata, Naoko Matsuki, Haruhiko Kondo, Hajime Takizawa, Annabelle A. Okada, Takashi Watanabe, Hiroaki Ohnishi

Published online on: September 20, 2018
Open Access

Lectin histochemical analysis of uterine natural killer cells in normal, hydatidiform molar and invasive molar pregnancy

Ting Zhong, Xingxing Xie, Teng Zong, Xiaochun Yu, Yan Ling, Haibin Kuang

Published online on: September 20, 2018
Open Access

A comprehensive gene mutation analysis of liquid biopsy samples from patients with metastatic colorectal cancer to the ovary: A case report

Naoyuki Iwahashi, Kazuko Sakai, Tomoko Noguchi, Tamaki Yahata, Saori Toujima, Kazuto Nishio, Kazuhiko Ino

Published online on: September 20, 2018

Genetic polymorphisms in CDH1 are associated with endometrial carcinoma susceptibility among Chinese Han women

Yue‑Hang Geng, Zi‑Fan Wang, Yu‑Mian Jia, Li‑Yuan Zheng, Lan Chen, Dong‑Ge Liu, Xiang‑Hong Li, Xin‑Xia Tian, Wei‑Gang Fang

Published online on: September 20, 2018
Open Access

Synergistic antitumor effect of the combination of a dual cancer‑specific oncolytic adenovirus and cisplatin on lung cancer cells

Jing Jin, Yilong Zhu, Fei Sun, Zhifei Chen, Shuang Chen, Yiquan Li, Wenjie Li, Min Li, Chuanxin Cui, Yingli Cui, Xunzhi Yin, Shanzhi Li, Jin Zhao, Guo Yan, Xiao Li, Ningyi Jin

Published online on: September 20, 2018
Open Access

Upregulation of circRNA_0000285 serves as a prognostic biomarker for nasopharyngeal carcinoma and is involved in radiosensitivity

Mingxia Shuai, Jangwei Hong, Donghai Huang, Xin Zhang, Yongquan Tian

Published online on: September 20, 2018

Utilizing ethacrynic acid and ciclopirox olamine in liver cancer

Ahmad M. Al‑Dali, Hans Weiher, Ingo G.H. Schmidt‑Wolf

Published online on: September 20, 2018
Open Access

Filamin A inhibits tumor progression through regulating BRCA1 expression in human breast cancer

Yundi Guo, Ming Li, Guanghui Bai, Xiaoning Li, Zhongwen Sun, Jie Yang, Lu Wang, Jing Sun

Published online on: September 20, 2018

Carcinogenesis‑related changes in iron metabolism in chronic obstructive pulmonary disease subjects with lung cancer

Kamil Brzóska, Teresa Bartłomiejczyk, Barbara Sochanowicz, Magdalena Cymerman, Jacek Grudny, Jacek Kołakowski, Marcin Kruszewski, Paweł Śliwiński, Kazimierz Roszkowski‑Śliż, Lucyna Kapka‑Skrzypczak

Published online on: September 19, 2018
Open Access

Identification of novel long non‑coding RNA in diffuse intrinsic pontine gliomas by expression profile analysis

Yuehui Liu, Haiping Liu, Dongwei Zhang

Published online on: September 19, 2018
Open Access

Invasive bronchial fibroblasts derived from asthmatic patients activate lung cancer A549 cells in vitro

Damian Ryszawy, Filip Rolski, Karolina Ryczek, Jessica Catapano, Tomasz Wróbel, Marta Michalik, Jarosław Czyż

Published online on: September 19, 2018

Oncological and renal outcomes of segmental ureterectomy vs. radical nephroureterectomy for upper tract urothelial carcinoma

Tomonori Kato, Ryo Nakayama, Tomomi Haba, Makoto Kawaguchi, Akira Komiya, Hiroshi Koike

Published online on: September 19, 2018
Open Access

MicroRNA 141 represses nasopharyngeal carcinoma growth through inhibiting BMI1

Fei Liu, Wenjuan Wang, Shuo Li, Qiong Yang, Jing Hu, Nan Zeng, Chunsheng Gao

Published online on: September 18, 2018
Open Access

EMT induced by loss of LKB1 promotes migration and invasion of liver cancer cells through ZEB1‑induced YAP signaling

Bijun Qiu, Wei Wei, Jianwen Zhu, Guangshun Fu, Dahai Lu

Published online on: September 18, 2018

miR‑221 regulates proliferation and apoptosis of ovarian cancer cells by targeting BMF

Xinping Xie, Yuxiu Huang, Lihong Chen, Jinhua Wang

Published online on: September 18, 2018
Open Access

Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review

Xiaorui Fu, Yufeng Shang, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Mingzhi Zhang

Published online on: September 18, 2018

Overexpression of sigma‑1 receptor in MCF‑7 cells enhances proliferation via the classic protein kinase C subtype signaling pathway

Yuqi Wu, Xueyan Bai, Xiaoyang Li, Chang Zhu, Zachary P. Wu

Published online on: September 18, 2018
Open Access

Knockdown of LETM1 inhibits proliferation and metastasis of human renal cell carcinoma cells

Jie Xu, Bisheng Huang, Saiyang Li, Xiaolu Zhang, Tiancheng Xie, Yunfei Xu

Published online on: September 18, 2018

Dihydroartemisinin triggers c‑Myc proteolysis and inhibits protein kinase B/glycogen synthase kinase 3β pathway in T‑cell lymphoma cells

Wenwen Wei, Xindong Zhao, Shaoling Wu, Chunting Zhao, Hongguo Zhao, Lingjie Sun, Yujiao Cui

Published online on: September 18, 2018
Open Access

miR‑491‑5p inhibits osteosarcoma cell proliferation by targeting PKM2

Ting Chen, Yuyang Li, Wenliang Cao, Yadong Liu

Published online on: September 18, 2018
Open Access

Ethnicity based variation in expression of E‑cadherin in patients with squamous cell carcinoma of the oral tongue

Nicola Sgaramella, Torben Wilms, Linda Boldrup, Lotta Loljung, Xiaolian Gu, Philip J. Coates, Petra Hassellöf, Luigi Califano, Lorenzo Lo Muzio, Robin Fåhraeus, Lena Norberg Spaak, Renato Franco, Gianpaolo Tartaro, Giuseppe Colella, Mario Santagata, Giovanni Dell'Aversana Orabona, Fabrizio Chirico, Karin Danielsson, Giuseppe Troiano, Fatima Ardito, Karin Nylander

Published online on: September 18, 2018
Open Access

MicroRNA‑661 expression is upregulated in pancreatic ductal adenocarcinoma and promotes cell proliferation

Feifei Lv, Kehong Zheng, Jinlong Yu, Zonghai Huang

Published online on: September 18, 2018

Hyperthermia enhances the sensitivity of pancreatic cancer SW1990 cells to gemcitabine through ROS/JNK signaling

Hangbin Jin, Yanyan Zhao, Jianfeng Yang, Xiaofeng Zhang, Shenglin Ma

Published online on: September 18, 2018

Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer

Jinling Zhang, Xueyuan Heng, Yi Luo, Luning Li, Haiyan Zhang, Fengyuan Che, Baosheng Li

Published online on: September 18, 2018
Open Access

Expression of miRNA‑206 and miRNA‑145 in breast cancer and correlation with prognosis

Yan Quan, Xianxi Huang, Xiaoxiang Quan

Published online on: September 17, 2018
Open Access

MicroRNA‑143 regulates cell migration and invasion by targeting GOLM1 in cervical cancer

Meiying Zhou, Xiaohong Chen, Jian Wu, Xiaoyan He, Rui Ren

Published online on: September 17, 2018
Open Access

Regulating glioma stem cells by hypoxia through the Notch1 and Oct3/4 signaling pathway

Fei Zeng, Hong Chen, Zhaohui Zhang, Tao Yao, Guan Wang, Qingxing Zeng, Shenhan Duan, Yanqiang Zhan

Published online on: September 17, 2018
Open Access

Imbalanced expression pattern of steroid receptor coactivator‑1 and ‑3 in liver cancer compared with normal liver: An immunohistochemical study with tissue microarray

Shan Li, Huiyan Zhang, Yanlan Yu, Mengying Liu, Deyu Guo, Xuqing Zhang, Jiqiang Zhang

Published online on: September 17, 2018

Plk1 promotes the migration of human lung adenocarcinoma epithelial cells via STAT3 signaling

Weijuan Yan, Huijie Yu, Wei Li, Fengsheng Li, Sinian Wang, Nan Yu, Qisheng Jiang

Published online on: September 14, 2018
Open Access

Synthesis and pharmacological evaluation of novel epidermal growth factor receptor inhibitors against prostate tumor cells

Yi Zhi, Xiaojun Wu, Wenhao Shen, Yongquan Wang, Xiaozhou Zhou, Peng He, Jinhong Pan, Zhiwen Chen, Weibing Li, Zhansong Zhou

Published online on: September 14, 2018

The SOX2OT/miR‑194‑5p axis regulates cell proliferation and mobility of gastric cancer through suppressing epithelial‑mesenchymal transition

Ruqiong Wei, Can Ding, Raquel Alarcòn Rodrìguez, Marìa del Mar Requena Mullor

Published online on: September 12, 2018

Progress in the chemotherapeutic treatment of osteosarcoma (Review)

Ya Zhang, Jingqing Yang, Na Zhao, Cao Wang, Santosh Kamar, Yonghong Zhou, Zewei He, Jifei Yang, Bin Sun, Xiaoqian Shi, Lei Han, Zuozhang Yang

Published online on: September 12, 2018
Open Access

Fractional uptake of circulating tumor cells into liver‑lung compartments during curative resection of periampullary cancer

Caroline Vilhav, Cecilia Engström, Peter Naredi, Ann Novotny, Johan Bourghardt‑Fagman, Britt‑Marie Iresjö, Annika G. Asting, Kent Lundholm

Published online on: September 12, 2018
Open Access

miR-145-5p inhibits the proliferation and migration of bladder cancer cells by targeting TAGLN2

Haijian Zhang, Meijuan Jiang, Qingjun Liu, Zhixing Han, Yuqian Zhao, Shiqi Ji

Published online on: September 12, 2018
Open Access

miR-34a targets BCL-2 to suppress the migration and invasion of sinonasal squamous cell carcinoma

Yigang Zhao, Xianzhi Wang

Published online on: September 11, 2018
Open Access

Therapeutic effects of lenvatinib in combination with rAd‑p53 for the treatment of non‑small cell lung cancer

Renzhi Yu, Minghuan Wang, Xiuli Zhu, Zhe Sun, Aiying Jiang, Huixin Yao

Published online on: September 11, 2018

Hsa‑miR‑376c‑3p targets Cyclin D1 and induces G1‑cell cycle arrest in neuroblastoma cells

Swapnil Parashram Bhavsar, Cecilie Løkke, Trond Flægstad, Christer Einvik

Published online on: September 11, 2018
Open Access

Barrier‑to‑autointegration factor 1: A novel biomarker for gastric cancer

Junjun Li, Bingbing Hu, Lei Fang, Yang Gao, Shuai Shi, Haoyu He, Xiaomei Liu, Caijun Yuan

Published online on: September 11, 2018
Open Access

Relationship between CT signs and the expression of miR‑146a in colon cancer

Zijian Liu, Yuzhu Li, Quanxiang Luo

Published online on: September 7, 2018
Open Access

High concordance of TMPRSS‑ERG fusion between primary prostate cancer and its lymph node metastases

Franziska Brandi, Katharina Grupp, Claudia Hube‑Magg, Martina Kluth, Dagmar Lang, Sarah Minner, Christina Möller‑Koop, Markus Graefen, Hans Heinzer, Maria Christina Tsourlakis, Corinna Wittmer, Frank Jacobsen, Hartwig Huland, Stefan Steurer, Patrick Lebok, Andrea Hinsch, Waldemar Wilczak, Thorsten Schlomm, Ronald Simon

Published online on: September 7, 2018
Open Access

Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin‑resistant oral cancer CAR cells through intrinsic apoptotic process

Chin‑Fu Chen, Chi‑Cheng Lu, Jo‑Hua Chiang, Hong‑Yi Chiu, Jai‑Sing Yang, Chao‑Ying Lee, Tzong‑Der Way, Hao‑Jen Huang

Published online on: September 7, 2018

Potential role of nuclear magnetic resonance spectroscopy to identify salivary metabolite alterations in patients with head and neck cancer

Jopi J.W. Mikkonen, Surya P. Singh, Ramin Akhi, Tuula Salo, Reijo Lappalainen, Wilfredo A. González‑Arriagada, Márcio Ajudarte Lopes, Arja M. Kullaa, Sami Myllymaa

Published online on: September 7, 2018
Open Access

Outcomes following liver resection for multinodular Barcelona Clinic Liver Cancer‑B hepatocellular carcinoma

Satoshi Matsukuma, Kazuhiko Sakamoto, Yoshihiro Tokuhisa, Yukio Tokumitsu, Hiroto Matsui, Shinsuke Kanekiyo, Shinobu Tomochika, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Tomio Ueno, Hiroshi Wada, Shogo Kobayashi, Issei Saeki, Hidetoshi Eguchi, Masato Sakon, Isao Sakaida, Hiroaki Nagano

Published online on: September 7, 2018
Open Access

Retrospective study of regorafenib and trifluridine/tipiracil efficacy as a third‑line or later chemotherapy regimen for refractory metastatic colorectal cancer

Akira Tanaka, Sotaro Sadahiro, Toshiyuki Suzuki, Kazutake Okada, Gota Saito, Hiroshi Miyakita

Published online on: September 7, 2018

Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN‑PD

Hiromichi Maeda, Ken‑Ichi Okada, Tsutomu Fujii, Mari S. Oba, Manabu Kawai, Seiko Hirono, Yasuhiro Kodera, Masayuki Sho, Takahiro Akahori, Yasuhiro Shimizu, Yoshiyasu Ambo, Naru Kondo, Yoshiaki Murakami, Jiro Ohuchida, Hidetoshi Eguchi, Hiroaki Nagano, Junichi Sakamoto, Hiroki Yamaue

Published online on: September 7, 2018

MicroRNA‑9‑5p functions as a tumor suppressor in papillary thyroid cancer via targeting BRAF

Feng Guo, Xinming Hou, Qinghui Sun

Published online on: September 7, 2018
Open Access

Arsenic trioxide induces the apoptosis and decreases NF‑κB expression in lymphoma cell lines

Lu Zhong, Fei Xu, Fangyuan Chen

Published online on: September 7, 2018
Open Access

Long non‑coding RNA, CHRF, predicts poor prognosis of lung adenocarcinoma and promotes cell proliferation and migration

Xiaowei Xie, Wei Zhao, Jinglin Pang, Xiaomiao Xiong, Haiyan Wang, Lingyun Ma

Published online on: September 7, 2018
Open Access

Butein induces apoptotic cell death of human cervical cancer cells

Pei‑Yu Yang, Dan‑Ning Hu, Ying‑Hsien Kao, I‑Ching Lin, Fu‑Shing Liu

Published online on: September 7, 2018

TM4SF1 inhibits apoptosis and promotes proliferation, migration and invasion in human gastric cancer cells

Yunhai Wei, Xiaoying Shen, Liqin Li, Guoliang Cao, Xuhua Cai, Yan Wang, Hua Shen

Published online on: September 6, 2018
Open Access

Pyk2 promotes tumor progression in renal cell carcinoma

Tangliang Zhao, Yi Bao, Xin Lu, Yi He, Xinxin Gan, Jianchao Wang, Bing Liu, Linhui Wang

Published online on: September 6, 2018

The novel three‑way variant t(6;17;15)(p21;q21;q22) in acute promyelocytic leukemia with an FLT3‑ITD mutation: A case report

Yong‑Lu Zhang, Mei Jiang, Shu‑Qing Luan, Shu‑Yuan Liu, Jin‑Hua Wan, La‑Gen Wan, Zhang‑Lin Zhang

Published online on: September 6, 2018
Open Access

Intra‑tumoral treatment with oxygen‑ozone in glioblastoma: A systematic literature search and results of a case series

Richard Megele, Markus J. Riemenschneider, Frank Dodoo‑Schittko, Matthias Feyrer, Andrea Kleindienst

Published online on: September 5, 2018
Open Access

Poly(ADP‑ribose) polymerase‑3 overexpression is associated with poor prognosis in patients with breast cancer following chemotherapy

Zhiguo Song, Yong Wang, Qinghuan Xia, Zhaojin Yu, Lin Zhao, Huizhe Wu, Mingli Sun, Zhangguo Chai, Ping Hou, Xiaoqiang Geng, Wensi Liu, Minjie Wei

Published online on: September 5, 2018

MicroRNA‑133a downregulated EGFR expression in human non‑small cell lung cancer cells via AKT/ERK signaling

Nannan Guo, Yingnan Zhao, Wen Zhang, Shaojun Li, Shanshan Li, Jianqi Yu

Published online on: September 5, 2018
Open Access

Downregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer

Jia Qi, Chunhui Cui, Quanwen Deng, Lifeng Wang, Rihong Chen, Duanyang Zhai, Lang Xie, Jinlong Yu

Published online on: September 5, 2018

β‑elemene induced anticancer effect in bladder cancer through upregulation of PTEN and suppression of AKT phosphorylation

Bo Cai, Limin Ma, Shaojun Nong, You Wu, Xin Guo, Jinxian Pu

Published online on: September 5, 2018

Anti‑IL‑20 monoclonal antibody suppresses hepatocellular carcinoma progression

Wen‑Zhou Ding, Guo‑Yong Han, Hui‑Han Jin, Chuan‑Fei Zhan, Yuan Ji, Xin‑Li Huang

Published online on: September 5, 2018
Open Access

SERINC2‑knockdown inhibits proliferation, migration and invasion in lung adenocarcinoma

Yuan Zeng, Dakai Xiao, Huiming He, Jiaxi He, Hui Pan, Wei Yang, Yaoqi Chen, Jianxing He

Published online on: September 5, 2018
Open Access

[Retracted] Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells

Yusuke Takehara, Toshiko Yamochi, Tasuku Nagumo, Tomonari Cho, Fumihiko Urushibara, Kohei Ono, Tomonori Fujii, Naoko Okamoto, Yosuke Sasaki, Sakiko Tazawa, Mayumi Honma, Tomoko Norose, Eisuke Shiozawa, Genshu Tate, Masafumi Takimoto

Published online on: September 5, 2018
Open Access

Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition

Rui Song, Ge Hou, Jun Yang, Jinjin Yuan, Cheng Wang, Ting Chai, Zongwen Liu

Published online on: September 5, 2018
Open Access

PAR4 overexpression promotes colorectal cancer cell proliferation and migration

Hongshan Zhang, Ping Jiang, Chuanrao Zhang, Siman Lee, Wei Wang, Hao Zou

Published online on: September 5, 2018

EPA significantly improves anti‑EGFR targeted therapy by regulating miR‑378 expression in colorectal cancer

Wen‑Hui Weng, Wai‑Hung Leung, Yeu Jye Pang, Li‑Wei Kuo, Hsi‑Hsien Hsu

Published online on: September 5, 2018
Open Access

Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China

Ying Liu, Lulu Xu, Hongliang Wu, Na Zhao, Yanchun Tang, Xiaoping Li, Ying Liang

Published online on: September 5, 2018
Open Access

Crizotinib induces apoptosis of lung cancer cells through JAK-STAT pathway

Hongmin Lu, Shibo Wu, Huafei Chen, Ying Huang, Guoqin Qiu, Lingxiang Liu, Yong Li

Published online on: September 4, 2018

Histone deacetylase inhibitors sensitize 5‑fluorouracil‑resistant MDA‑MB‑468 breast cancer cells to 5‑fluorouracil

Tetsuya Minegaki, Ai Suzuki, Misato Mori, Shiori Tsuji, Satoshi Yamamoto, Airi Watanabe, Tomoyo Tsuzuki, Takaki Tsunoda, Asuka Yamamoto, Masayuki Tsujimoto, Kohshi Nishiguchi

Published online on: September 4, 2018
Open Access

Feasibility of 2D‑conformal radiotherapy for pancreatic carcinoma

Milly Buwenge, Savino Cilla, Silvia Cammelli, Gabriella Macchia, Alessandra Arcelli, Eleonora Farina, Rezarta Frakulli, Valeria Panni, Tigeneh Wondemagegnhu, A. F. M. Kamal Uddin, Mostafa A. Sumon, Francesco Deodato, Alessio G. Morganti

Published online on: September 4, 2018
Open Access

DNMTs inhibitor SGI‑1027 induces apoptosis in Huh7 human hepatocellular carcinoma cells

Ning Sun, Jialin Zhang, Chengshuo Zhang, Bochao Zhao, Ao Jiao

Published online on: September 4, 2018
Open Access

Elevated expression of POLD1 is associated with poor prognosis in breast cancer

Qinghong Qin, Qixing Tan, Jinyuan Li, Weiping Yang, Bin Lian, Qinguo Mo, Changyuan Wei

Published online on: September 4, 2018
Open Access

Gastric cancer initially presenting as bone metastasis: Two case reports and a literature review

Daisuke Gomi, Toshirou Fukushima, Takashi Kobayashi, Nodoka Sekiguchi, Akiyuki Sakamoto, Keiko Mamiya, Tomonobu Koizumi

Published online on: September 4, 2018
Open Access

Trends of incidence and survival in patients with gastrointestinal mucinous adenocarcinoma

Zhen Zong, Yonghui Luo, Houqun Ying, Anan Wang, Hui Li, Chenghao Yi

Published online on: September 4, 2018

Emerging function of N6‑methyladenosine in cancer (Review)

Kwonho Hong

Published online on: September 4, 2018
Open Access

A‑kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide‑induced liver injury

Hye Shin Lee, Jinhyeok Choi, Taekwon Son, Eun Ji Lee, Jeong‑Gyun Kim, Soo Hyung Ryu, Danbi Lee, Myoung Kuk Jang, Eunsil Yu, Young‑Hwa Chung, Irwin H. Gelman, Kyu‑Won Kim

Published online on: September 4, 2018

Effects of NOTCH1 signaling inhibitor γ‑secretase inhibitor II on growth of cancer stem cells

Xiaodong Ding, Changqing Ding, Fei Wang, Wenshuai Deng, Mingming Yu, Qinghai Meng, Peng Sun

Published online on: September 3, 2018

Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF‑κB/caspase‑3 signaling pathways

Xin Zhang, Ping Fang, Zigang Zhao, Xiangyu Ding, Fang Xie, Yilin Wang, Chengxin Li

Published online on: September 3, 2018
Open Access

Aberrant cystatin‑C expression in blood from patients with breast cancer is a suitable marker for monitoring tumor burden

Woo Sun Kwon, Tae Soo Kim, Chung Hyun Nahm, Yeonsook Moon, Jin Ju Kim

Published online on: September 3, 2018
Open Access

Upregulation of stem cell markers ALDH1A1 and OCT4 as potential biomarkers for the early detection of cervical carcinoma

Wuniqiemu Tulake, Reziwanguli Yuemaier, Lei Sheng, Mingfang Ru, Dilare Lidifu, Abulizi Abudula

Published online on: September 3, 2018

Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene

Jiacui Zhang, Keping Jiao, Jing Liu, Yu Xia

Published online on: September 3, 2018
Open Access

Gastric cancer with breast metastasis: Clinical features and prognostic factors

Yue Ma, Wenwen Liu, Junjian Li, Yingchun Xu, Hongxia Wang

Published online on: September 3, 2018
Open Access

Identification of eight key miRNAs associated with renal cell carcinoma: A meta‑analysis

Guanghui Ying, Ruilan Wu, Min Xia, Xiapei Fei, Qi En He, Chenqin Zha, Fuquan Wu

Published online on: September 3, 2018

CHSY1 promoted proliferation and suppressed apoptosis in colorectal cancer through regulation of the NFκB and/or caspase‑3/7 signaling pathway

Lifeng Zeng, Jinrong Qian, Xiaojiang Luo, Aiqun Zhou, Zhiyong Zhang, Quangang Fang

Published online on: September 3, 2018
Open Access

Expression of TRPM8 in human reactive lymphoid tissues and mature B‑cell neoplasms

Akinori Hirai, Naing Ye Aung, Rintaro Ohe, Akiko Nishida, Tomoya Kato, Hongxue Meng, Kenichi Ishizawa, Junichi Fujii, Mitsunori Yamakawa

Published online on: September 3, 2018
Open Access

Correlation of nm 23 expression with pharyngeal cancer and patient prognoses

Wenzhong Wei, Xin Wei, Xiao Liang

Published online on: August 31, 2018
Open Access

miR‑339‑5p inhibits lung adenocarcinoma invasion and migration by directly targeting BCL6

Peng Li, Huaqing Liu, Yanmeng Li, Yan Wang, Lin Zhao, Hui Wang

Published online on: August 31, 2018
Open Access

Tumor suppression by Tegafur combined with Barbadian in S‑180 tumor‑bearing mice

Enning Zhang, Aiqin Fu, Weijun Chen, Xiaojie Wang

Published online on: August 30, 2018
Open Access

Effects of TACE combined with precise RT on p53 gene expression and prognosis of HCC patients

Yupeng Liu, Jingchen Yan, Feng Wang

Published online on: August 30, 2018
Open Access

Effects and mechanism of STAT3 silencing on the growth and apoptosis of colorectal cancer cells

Jing Li, You‑Yu Liu, Xue‑Feng Yang, Dao‑Fu Shen, Hong‑Zhi Sun, Ke‑Qiang Huang, Hua‑Chuan Zheng

Published online on: August 29, 2018
Open Access

Complete endoscopic radical resection of thyroid cancer via an oral vestibule approach

Cong Bian, Hui Liu, Xi‑Yu Yao, Shu‑Ping Wu, Yu Wu, Chang Liu, Tian‑Shun Huang

Published online on: August 29, 2018

Somatic mutation profiling of liver and biliary cancer by targeted next generation sequencing

Bo‑Lun Zhang, Xu Ji, Ling‑Xiang Yu, Yuan Gao, Chao‑Hui Xiao, Jia Liu, De‑Xi Zhao, Yi Le, Guang‑Hao Diao, Jia‑Yi Sun, Gao‑Hua Li, Guang‑Lin Lei, Peng Yu, Rui‑Lan Wang, Jian‑Zhong Wu, Peng‑Hui Yang, Jin Yan, Jing‑Yu Li, Jia‑Jia Xu, Shao‑Geng Zhang, Hu Tian

Published online on: August 29, 2018

Expression and significance of quantum dots in RAW 264.7 macrophages

Chong Li, Panpan Zhang, Yanming Hao, Dawei He, Yixin Shen, Rongzhu Lu

Published online on: August 24, 2018
Open Access

microRNA‑214 suppresses the growth of cervical cancer cells by targeting EZH2

Yanling Yang, Yang Liu, Guilin Li, Lei Li, Peng Geng, Hongjuan Song

Published online on: August 24, 2018
Open Access

Puerarin 6''‑O‑xyloside possesses significant antitumor activities on colon cancer through inducing apoptosis

Xiao‑Lan Zhang, Bin‑Bin Wang, Jian‑Shu Mo

Published online on: August 24, 2018

Prognostic impact of soluble intercellular adhesion molecule‑1 in hepatocellular carcinoma

Tatsuo Shimura, Masahiko Shibata, Kenji Gonda, Yasuhide Kofunato, Teruhide Ishigame, Ryo Okada, Naoya Sato, Takashi Kimura, Akira Kenjo, Shigeru Marubashi

Published online on: August 24, 2018
Open Access

Interaction of polymorphisms in xeroderma pigmentosum group C with cigarette smoking and pancreatic cancer risk

Xiao‑Hui Liang, Dong Yan, Jia‑Xing Zhao, Wei Ding, Xin‑Jian Xu, Xi‑Yan Wang

Published online on: August 23, 2018

Differential expression profiles of microRNAs in highly and weakly invasive/metastatic pancreatic cancer cells

Xiaodong Tan, Lei Zhou, Huaitao Wang, Yifan Yang, Yang Sun, Zhaoping Wang, Xiaobo Zhang, Feng Gao, Hansi Li

Published online on: August 23, 2018

The role of protein p16INK4a in non‑oropharyngeal head and neck squamous cell carcinoma in Southern China

Hang Yang, Ye Cao, Zhi‑Ming Li, Ya‑Jun Li, Wen‑Qi Jiang, Yan‑Xia Shi

Published online on: August 23, 2018

Potential function of CTLA‑4 in the tumourigenic capacity of melanoma stem cells

Bingyu Zhang, Jianzhong Dang, Diandian Ba, Cencen Wang, Juan Han, Fang Zheng

Published online on: August 23, 2018
Open Access

Apatinib suppresses cell growth and metastasis and promotes antitumor activity of temozolomide in glioma

Chao Wang, Man Jiang, Helei Hou, Qiang Lin, Zhiyong Yan, Xiaochun Zhang

Published online on: August 23, 2018
Open Access

Leptin and its receptor in glucose metabolism of T‑cell lymphoma

Tian‑Jie Han, Hong‑Zhi Xu, Jun‑Shan Li, Ling‑Yun Geng, Xin‑Yu Li, Xiang‑Xiang Zhou, Xin Wang

Published online on: August 23, 2018
Open Access

Overexpression of circ‑0067934 is associated with increased cellular proliferation and the prognosis of non‑small cell lung cancer

Qinguang Zou, Tiejun Wang, Bai Li, Guanghu Li, Lixin Zhang, Bao Wang, Shaolin Sun

Published online on: August 23, 2018

Serum vascular endothelial growth factor‑C levels predict lymph node metastasis and prognosis of patients with gallbladder cancer

Lei Jiang, Minchao Liu, Xinran Cai, Lijun Xie, Feifei She, Yanling Chen

Published online on: August 23, 2018
Open Access

Hepatitis B virus X protein promotes epithelial‑mesenchymal transition and metastasis in hepatocellular carcinoma cell line HCCLM3 by targeting HMGA2

Yong Zha, Qian Yao, Jin‑Sheng Liu, Yuan‑Yuan Wang, Wei‑Ming Sun

Published online on: August 23, 2018
Open Access

Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180

Xiao‑Yun Li, Xiao‑Feng Liao, Hong‑Bo Wang, Jian Zhang

Published online on: August 23, 2018

AQP9 promotes astrocytoma cell invasion and motility via the AKT pathway

Yao Lv, Qiang Huang, Weimin Dai, Yuanqing Jie, Guofeng Yu, Xiaofeng Fan, An Wu, Qian Miao

Published online on: August 23, 2018
Open Access

Role of nutritional support for postoperative recovery of respiratory function in patients with primary lung cancer

Jinhong Yang, Qianqian Zhang, Xiaoli Wang

Published online on: August 22, 2018
Open Access

The LINC01186 suppresses cell proliferation and invasion ability in papillary thyroid carcinoma

Nanpeng Wang, Haisong Duan, Chen Zhang, Yan Zhou, Rongjun Gao

Published online on: August 22, 2018
Open Access

Identification of ceRNA network based on a RNA‑seq shows prognostic lncRNA biomarkers in human lung adenocarcinoma

Xing Li, Bing Li, Pixin Ran, Lanying Wang

Published online on: August 21, 2018
Open Access

Expression of PD‑L1 and SOX2 during rectal tumourigenesis: Potential mechanisms for immune escape and tumour cell invasion

Tim J. Miller, Melanie J. Mccoy, Christine Hemmings, Barry Iacopetta, Cameron F. Platell

Published online on: August 21, 2018
Open Access

A 20(S)‑protopanaxadiol derivative PPD12 reverses ABCB1‑mediated multidrug resistance with oral bioavailability and low toxicity

Shunfeng Wei, Wantao Chen, Lihong Hu, Jinsong Pan, Xu Wang

Published online on: August 21, 2018
Open Access

Combined expression of protein disulfide isomerase and endoplasmic reticulum oxidoreductin 1‑α is a poor prognostic marker for non‑small cell lung cancer

Kyoung Min Kim, Ae Ri An, Ho Sung Park, Kyu Yun Jang, Woo Sung Moon, Myoung Jae Kang, Yong Chul Lee, Ja Hong Ku, Myoung Ja Chung

Published online on: August 21, 2018

Kaempferol, a natural dietary flavonoid, suppresses 17β‑estradiol‑induced survivin expression and causes apoptotic cell death in endometrial cancer

Agapiti Hipoliti Chuwa, Kenbun Sone, Katsutoshi Oda, Michihiro Tanikawa, Asako Kukita, Machiko Kojima, Shinya Oki, Tomohiko Fukuda, Makoto Takeuchi, Aki Miyasaka, Tomoko Kashiyama, Yuji Ikeda, Kazunori Nagasaka, Mayuyo Mori‑Uchino, Yoko Matsumoto, Osamu Wada‑Hiraike, Hiroyuki Kuramoto, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii

Published online on: August 21, 2018
Open Access

miR‑124 regulates STAT3‑mediated cell proliferation, migration and apoptosis in bladder cancer

Shengxing Wang, Gang Wu, Yinan Han, Peng Song, Jinhuo Chen, Yaoxi Wu, Jie Yang, Peiyu Liang

Published online on: August 21, 2018
Open Access

Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer

Yang Wang, Chunhui Zheng, Teng Li, Rui Zhang, Jiaxin Zhang, Qingsi He, Zuocheng Sun, Xinsheng Wang

Published online on: August 21, 2018

Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells

Tao Tian, Jinpeng Sun, Jianxin Wang, Yanchun Liu, Haitao Liu

Published online on: August 21, 2018

Serum thymidine kinase 1 is associated with Gleason score of patients with prostate carcinoma

Shujing Li, Jianping Zhou, Yu Wang, Keqin Zhang, Junjie Yang, Xinling Zhang, Chunmei Wang, Hongbo Ma, Ji Zhou, Ellen He, Sven Skog

Published online on: August 21, 2018
Open Access

Iodine‑125 interstitial brachytherapy reduces tumor growth via Warburg effect inhibition in non‑small cell lung cancer A549 xenografts

Jun Zhang, Yangjun Zhu, Mengjie Dong, Jun Yang, Wanwen Weng, Lisong Teng

Published online on: August 21, 2018

Viability of glioblastoma stem cells is effectively reduced by diisothiocyanate‑derived mercapturic acids

Kamila Cwiklowska, Mike‑Andrew Westhoff, Simon Freisinger, Annika Dwucet, Marc‑Eric Halatsch, Uwe Knippschild, Klaus‑Michael Debatin, Reinhold Schirmbeck, Lukasz Winiarski, Jozef Oleksyszyn, Christian Rainer Wirtz, Timo Burster

Published online on: August 21, 2018
Open Access

CDH13 promoter methylation regulates cisplatin resistance of non-small cell lung cancer cells

Yan Wang, Lei Zhang, Jiasheng Yang, Bin Li, Jun Wang

Published online on: August 20, 2018
Open Access

MicroRNA‑206 suppresses proliferation and predicts poor prognosis of HR‑HPV-positive cervical cancer cells by targeting G6PD

Jinpeng Cui, Yinghua Pan, Jianhua Wang, Yan Liu, Hongyan Wang, Hongyan Li

Published online on: August 20, 2018

Effects of let‑7c on the proliferation of ovarian carcinoma cells by targeted regulation of CDC25a gene expression

Wei Zhang, Qingru Zeng, Zhenying Ban, Jing Cao, Tianjiao Chu, Dongmei Lei, Chi Liu, Wentao Guo, Xianxu Zeng

Published online on: August 20, 2018
Open Access

Never‑in‑mitosis A‑related kinase 8, a novel target of von‑Hippel‑Lindau tumor suppressor protein, promotes gastric cancer cell proliferation

Xiao‑Fei Ding, Jie Chen, Jun Zhou, Guang Chen, Ying‑Liang Wu

Published online on: August 20, 2018
Open Access

A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer

Yoichiro Kato, Hitoshi Zembutsu, Ryo Takata, Tomohiko Matsuura, Renpei Kato, Mitsugu Kanehira, Kazuhiro Iwasaki, Noriyuki Yamada, Toyomasa Katagiri, Tamotsu Sugai, Tomoaki Fujioka, Yusuke Nakamura, Wataru Obara

Published online on: August 20, 2018
Open Access

Antitumor effect of ginsenoside Rg3 on gallbladder cancer by inducing endoplasmic reticulum stress‑mediated apoptosis in vitro and in vivo

Keren Wu, Jie Huang, Ning Li, Tao Xu, Wenyu Cai, Zhipeng Ye

Published online on: August 20, 2018

A dosimetric study on radiation‑induced hypothyroidism following intensity‑modulated radiotherapy in patients with nasopharyngeal carcinoma

Yumei Xu, Zhiying Shao, Tianyou Tang, Guihong Liu, Yuanhu Yao, Jianshe Wang, Longzhen Zhang

Published online on: August 20, 2018

Genomic profiling of synchronous triple primary tumors of the lung, thyroid and kidney in a young female patient: A case report

Ling Peng, Zhu Zeng, Xiaodong Teng, Zhen Chen, Lili Lin, Hua Bao, Yang W. Shao, Yina Wang, Yongquan Dong, Qiong Zhao

Published online on: August 20, 2018
Open Access

MicroRNA‑217 functions as a tumor suppressor in cervical cancer cells through targeting Rho‑associated protein kinase 1

Jing Dong, Maoxiu Wang, Donghua Ni, Lixin Zhang, Wen Wang, Xiujuan Cui, Shijie Fu, Shujuan Yao

Published online on: August 20, 2018
Journal Cover

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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