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HIGHER FREQUENCY OF RAS ONCOGENE ACTIVATION IN GASTRIC STUMP CARCINOMAS DUE TO SPECIAL CONDITIONS IN THE GASTRIC REMNANT

  • Authors:
    • S FUSHIDA
    • Y YONEMURA
    • T URANO
    • K TSUGAWA
    • I MIYAZAKI
    • H SHIKU

  • View Affiliations

  • Published online on: January 1, 1994     https://doi.org/10.3892/or.1.1.111
  • Pages: 111-115
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Abstract

Gastric stump carcinoma is now widely recognized to be due to special conditions in the gastric remnant. To examine whether the mechanism of carcinogenesis is different in gastric stump carcinoma from other gastric carcinoma, we analyzed ras mutation in 62 gastric carcinomas. The ras mutation frequency was 4/17 (23.5%) in stump carcinomas, 2/25 (8.0%) in other remnant carcinomas and 1/20 (5.0%) in proximal carcinomas. The mutation frequency in stump carcinomas was much higher than that in other gastric carcinomas. These results suggest that the mechanism of carcinogenesis in gastric stump carcinomas may be different from other gastric carcinomas.

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January 1994
Volume 1 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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  • Source Normalized Impact per Paper (SNIP): 0.786
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Spandidos Publications style
FUSHIDA S, YONEMURA Y, URANO T, TSUGAWA K, MIYAZAKI I and SHIKU H: HIGHER FREQUENCY OF RAS ONCOGENE ACTIVATION IN GASTRIC STUMP CARCINOMAS DUE TO SPECIAL CONDITIONS IN THE GASTRIC REMNANT. Oncol Rep 1: 111-115, 1994
APA
FUSHIDA, S., YONEMURA, Y., URANO, T., TSUGAWA, K., MIYAZAKI, I., & SHIKU, H. (1994). HIGHER FREQUENCY OF RAS ONCOGENE ACTIVATION IN GASTRIC STUMP CARCINOMAS DUE TO SPECIAL CONDITIONS IN THE GASTRIC REMNANT. Oncology Reports, 1, 111-115. https://doi.org/10.3892/or.1.1.111
MLA
FUSHIDA, S., YONEMURA, Y., URANO, T., TSUGAWA, K., MIYAZAKI, I., SHIKU, H."HIGHER FREQUENCY OF RAS ONCOGENE ACTIVATION IN GASTRIC STUMP CARCINOMAS DUE TO SPECIAL CONDITIONS IN THE GASTRIC REMNANT". Oncology Reports 1.1 (1994): 111-115.
Chicago
FUSHIDA, S., YONEMURA, Y., URANO, T., TSUGAWA, K., MIYAZAKI, I., SHIKU, H."HIGHER FREQUENCY OF RAS ONCOGENE ACTIVATION IN GASTRIC STUMP CARCINOMAS DUE TO SPECIAL CONDITIONS IN THE GASTRIC REMNANT". Oncology Reports 1, no. 1 (1994): 111-115. https://doi.org/10.3892/or.1.1.111