Expression of alpha-smooth-muscle actin antigen in thymoma and thymic cancer

  • Authors:
    • Y Ohta
    • N Ishikawa
    • S Murakami
    • M Oda
    • Y Endo
    • T Sasaki
    • Y Watanabe
  • View Affiliations

  • Published online on: September 1, 1997     https://doi.org/10.3892/or.4.5.893
  • Pages: 893-897
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Abstract

Using specimens from 95 patients with thymoma and 6 with thymic cancer, we studied the expression of an alpha-smooth-muscle actin antigen immunohistochemically. It was mainly identified in the cytoplasm of small spindle cells within stroma and in the cytoplasm of tumor cells excepting vessels. In thymomas, the stromal expression is related to poor survival, while the cytoplasmic expression within tumor cells correlate with good outcome. Our data indicate that significance of the smooth muscle differentiation may be different between stromal and tumor cells. This antigen may be a useful indicator of survival in thymic neoplasms, especially in thymoma.

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September 1997
Volume 4 Issue 5

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Ohta Y, Ishikawa N, Murakami S, Oda M, Endo Y, Sasaki T and Watanabe Y: Expression of alpha-smooth-muscle actin antigen in thymoma and thymic cancer. Oncol Rep 4: 893-897, 1997
APA
Ohta, Y., Ishikawa, N., Murakami, S., Oda, M., Endo, Y., Sasaki, T., & Watanabe, Y. (1997). Expression of alpha-smooth-muscle actin antigen in thymoma and thymic cancer. Oncology Reports, 4, 893-897. https://doi.org/10.3892/or.4.5.893
MLA
Ohta, Y., Ishikawa, N., Murakami, S., Oda, M., Endo, Y., Sasaki, T., Watanabe, Y."Expression of alpha-smooth-muscle actin antigen in thymoma and thymic cancer". Oncology Reports 4.5 (1997): 893-897.
Chicago
Ohta, Y., Ishikawa, N., Murakami, S., Oda, M., Endo, Y., Sasaki, T., Watanabe, Y."Expression of alpha-smooth-muscle actin antigen in thymoma and thymic cancer". Oncology Reports 4, no. 5 (1997): 893-897. https://doi.org/10.3892/or.4.5.893