Early Online

Open Access

Aberrantly expressed genes and miRNAs in human hypopharyngeal squamous cell carcinoma based on RNA‑sequencing analysis

Hu Li, Fuling Wang, Yonghua Fei, Yanhua Lei, Fengxiang Lu, Ping Guo, Wei Li, Xuehong Xun

Published online on: June 19, 2018

HBsAg/β2GPI activates the NF‑κB pathway via the TLR4/MyD88/IκBα axis in hepatocellular carcinoma

Xue Jing, Zibin Tian, Pujun Gao, Huashi Xiao, Xiaolong Qi, Yanan Yu, Xueli Ding, Lin Yang, Liang Zong

Published online on: June 19, 2018

Association between methylation of tumor suppressor gene SOCS1 and acute myeloid leukemia

Xiao‑Hui Zhang, Lin Yang, Xiao‑Jun Liu, Ying Zhan, Yu‑Xia Pan, Xing‑Zhe Wang, Jian‑Min Luo

Published online on: June 19, 2018

XBP1 promotes tumor invasion and is associated with poor prognosis in oral squamous cell carcinoma

Yanan Sun, Fangyan Jiang, Yuemei Pan, Xinming Chen, Jirong Chen, Yu Wang, Xueqing Zheng, Jiali Zhang

Published online on: June 18, 2018

A novel strategy of EGFR‑TKI combined chemotherapy in the treatment of human lung cancer with EGFR‑sensitive mutation

Lanlin Zhang, Yuan Qi, Kailin Xing, Song Qian, Ping Zhang, Xianghua Wu

Published online on: June 18, 2018

HGF derived from cancer‑associated fibroblasts promotes vascularization in gastric cancer via PI3K/AKT and ERK1/2 signaling

Xusheng Ding, Wenqi Xi, Jun Ji, Qu Cai, Jinling Jiang, Min Shi, Yingyan Yu, Zhenggang Zhu, Jun Zhang

Published online on: June 18, 2018
Open Access

Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues

Hirosumi Tamura, Arisa Higa, Hirotaka Hoshi, Gen Hiyama, Nobuhiko Takahashi, Masae Ryufuku, Gaku Morisawa, Yuka Yanagisawa, Emi Ito, Jun-Ichi Imai, Yuu Dobashi, Kiyoaki Katahira, Shu Soeda, Takafumi Watanabe, Keiya Fujimori, Shinya Watanabe, Motoki Takagi

Published online on: June 18, 2018

Long non-coding RNA BANCR regulates cancer stem cell markers in papillary thyroid cancer via the RAF/MEK/ERK signaling pathway

Yuanyuan Wang, Xiangde Lin, Xinghao Fu, Wei Yan, Fusheng Lin, Penghao Kuang, Yezhe Luo, Ende Lin, Xiaoquan Hong, Guoyang Wu

Published online on: June 18, 2018

Androgen receptor induces EPHA3 expression by interacting with transcription factor SP1

Xiaowei Diao, Xiubin Chen, Yurui Pi, Yu Zhang, Fangfang Wang, Ping Liu, Yanhong Gao, Xiaojun Wang, Sijun Yang, Shan Lu

Published online on: June 18, 2018
Open Access

SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP‑2

Meng Xu, Huamao Jaing, Haiguang Wang, Jiajie Liu, Baohao Liu, Zhongqiang Guo

Published online on: June 18, 2018

Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression

Romina Canzoneri, Martín Enrique Rabassa, Agustina Gurruchaga, Valeria Ferretti, Sabina Palma, Marina Isla‑Larrain, María Virginia Croce, Ezequiel Lacunza, Martín Carlos Abba

Published online on: June 14, 2018

Enhanced expression of SETDB1 possesses prognostic value and promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma

Jing Huang, Weiyuan Huang, Mei Liu, Jianping Zhu, Danxian Jiang, Yinghuan Xiong, Yan Zhen, Donghong Yang, Zihong Chen, Lijiao Peng, Zhonghua Yu

Published online on: June 14, 2018

Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells

Yueling Yuan, Peter Chiba, Tiange Cai, Richard Callaghan, Li Bai, Susan P.C. Cole, Yu Cai

Published online on: June 14, 2018
Open Access

Diagnostic value and lymph node metastasis prediction of a custom‑made panel (thyroline) in thyroid cancer

Zunfu Ke, Yihao Liu, Yunjian Zhang, Jie Li, Ming Kuang, Sui Peng, Jinyu Liang, Shuang Yu, Lei Su, Lili Chen, Cong Sun, Bin Li, Jessica Cao, Weiming Lv, Haipeng Xiao

Published online on: June 14, 2018

Wnt signaling pathway upregulates DNMT1 to trigger NHERF1 promoter hypermethylation in colon cancer

Yongli Guo, Meng Wang, Xuefeng Jia, Hua Zhu, Yaqin Zhi, Leilei Yuan

Published online on: June 14, 2018
Open Access

[Corrigendum] LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells

Ye Wei, Tiantian Han, Ranran Wang, Jing Wei, Ke Peng, Qiong Lin, Genbao Shao

Published online on: June 14, 2018

Trop2 is a potential biomarker for the promotion of EMT in human breast cancer

Wei Zhao, Xingwang Kuai, Xueyi Zhou, Lizhou Jia, Jinsong Wang, Xiaobing Yang, Zhidan Tian, Xiaolei Wang, Qian Lv, Bin Wang, Youcai Zhao, Wenbin Huang

Published online on: June 14, 2018

γ-tocotrienol inhibits the invasion and migration of human gastric cancer cells through downregulation of cyclooxygenase-2 expression

Ya Hui Zhang, Ke Ma, Jia Ren Liu, Hai Xia Wang, Wen Xia Tian, Yue Hua Tu, Wen Guang Sun

Published online on: June 14, 2018

Overexpression of miR-140-5p inhibits lipopolysaccharide-induced human intervertebral disc inflammation and degeneration by downregulating toll-like receptor 4

Qiang Zhang, Yiping Weng, Yuqing Jiang, Shujie Zhao, Dong Zhou, Nanwei Xu

Published online on: June 12, 2018

DKC1 serves as a potential prognostic biomarker for human clear cell renal cell carcinoma and promotes its proliferation, migration and invasion via the NF‑κB pathway

Meng Zhang, Yu Pan, Ranran Jiang, Pingfu Hou, Haixia Shan, Fang Chen, Tao Jiang, Jin Bai, Junnian Zheng

Published online on: June 11, 2018

Curcumin inhibits liver cancer by inhibiting DAMP molecule HSP70 and TLR4 signaling

Biqiong Ren, Shudi Luo, Xuefei Tian, Zhichao Jiang, Guoying Zou, Fei Xu, Tieqiu Yin, Yiran Huang, Junlong Liu

Published online on: June 11, 2018

Upregulated miR‑20a‑5p expression promotes proliferation and invasion of head and neck squamous cell carcinoma cells by targeting of TNFRSF21

Hong Wu, Pai Pang, Min‑Da Liu, Song Wang, Shan Jin, Fa‑Yu Liu, Chang‑Fu Sun

Published online on: June 7, 2018

AAED1 modulates proliferation and glycolysis in gastric cancer

Beili Zhang, Jugang Wu, Yantao Cai, Meng Luo, Bing Wang, Yan Gu

Published online on: June 7, 2018

Protein kinase D1 regulates hypoxic metabolism through HIF-1α and glycolytic enzymes incancer cells

Jiao Chen, Bomiao Cui, Yaping Fan, Xiaoying Li, Qian Li, Yue Du, Yun Feng, Ping Zhang

Published online on: June 7, 2018

uc.338 targets p21 and cyclin D1 via PI3K/AKT pathway activation to promote cell proliferation in colorectal cancer

Yue Zhang, Shijia Wang, Wenwei Qian, Dongjian Ji, Qingyuan Wang, Zhiyuan Zhang, Sen Wang, Bing Ji, Zan Fu, Yueming Sun

Published online on: June 7, 2018

Aberrant expression of FoxP3 in a human T cell line possessing regulatory T cell‑like function and exposed continuously to asbestos fibers

Megumi Maeda, Hidenori Matsuzaki, Shoko Yamamoto, Suni Lee, Naoko Kumagai‑Takei, Kei Yoshitome, Yu Min, Nagisa Sada, Yasumitsu Nishimura, Takemi Otsuki

Published online on: June 7, 2018
Open Access

Fibroblast growth factor 18 promotes the growth, migration and invasion of MDA‑MB‑231 cells

Ziyi Yu, Longquan Lou, Yi Zhao

Published online on: June 7, 2018

Timed‑flat infusion of 5‑fluorouracil with docetaxel and oxaliplatin as first‑line treatment of gastroesophageal adenocarcinoma: A single institution experience with the FD/FOx regimen

Alessio Cortellini, Katia Cannita, Alessandro Parisi, Olga Venditti, Paola Lanfiuti Baldi, Berardo De Berardis, Roberto Vicentini, Vincenzo Vicentini, Lucilla Verna, Giampiero Porzio, Corrado Ficorella

Published online on: June 6, 2018

Prognostic signatures for renal cancer as identified by long non-coding and miRNA competing endogenous network analysis.

Hongwei Gao, Xuanrong Chen, Zhiqun Shang, Yuanjie Niu

Published online on: June 6, 2018

Preliminary mechanisms of regulating PD‑L1 expression in non‑small cell lung cancer during the EMT process

Fang Li, Tengjiao Zhu, Yao Yue, Xiang Zhu, Jiadong Wang, Li Liang

Published online on: June 5, 2018

Estrogen‑related receptor γ promotes the migration and metastasis of endometrial cancer cells by targeting S100A4

Teng Hua, Xiaoxiao Wang, Shuqi Chi, Yan Liu, Dilu Feng, Yingchao Zhao, Hongbo Wang

Published online on: June 4, 2018

A novel biphenyl urea compound, TPD7, stimulates apoptosis through modulating Fas signaling and Bcl-2 family proteins in cervical cancer

Yingzhuan Zhan, Han Zhang, Bingling Dai, Yanmin Zhang, Jie Zhang, Langchong He

Published online on: June 4, 2018
Open Access

Sperm‑associated antigen 4 (SPAG4) as a new cancer marker interacts with Nesprin3 to regulate cell migration in lung carcinoma

Ying Ji, Jinquan Jiang, Lihua Huang, Wei Feng, Zhang Zhang, Longyu Jin, Xiaowei Xing

Published online on: June 4, 2018
Open Access

Girdin regulates the proliferation and apoptosis of pancreatic cancer cells via the PI3K/Akt signalling pathway

Sheng Wang, Yiqun Lei, Zeling Cai, Xiaoman Ye, Lianhong Li, Xiagang Luo, Chunzhao Yu

Published online on: May 31, 2018

G‑protein‑coupled receptor 120 regulates the development and progression of human esophageal cancer

Zhen Cui, Duojie Li, Jingjing Liu, Yajun Zhang, Hongbo Xu, Hongmei Yin, Hongwei Li, Gengming Wang, Hanfei Cai, Lei Zhang, Shimiao Duan, Hao Jiang

Published online on: May 31, 2018

Cdc20 inhibitor apcin inhibits the growth and invasion of osteosarcoma cells

Yuan Gao, Benyuan Zhang, Yuming Wang, Guanning Shang

Published online on: May 30, 2018
Open Access

Genistein and AG1024 synergistically increase the radiosensitivity of prostate cancer cells

Qisheng Tang, Jianjun Ma, Jinbo Sun, Longfei Yang, Fan Yang, Wei Zhang, Ruixiao Li, Lei Wang, Yong Wang, He Wang

Published online on: May 30, 2018

Montelukast, a cysteinyl leukotriene receptor antagonist, inhibits the growth of chronic myeloid leukemia cells through apoptosis

Ana Zovko, Elham Yektaei-Karin, Daniel Salamon, Anders Nilsson, Jonas Wallvik, Leif Stenke

Published online on: May 25, 2018

Elevated TFAP4 regulates lncRNA TRERNA1 to promote cell migration and invasion in gastric cancer

Huazhang Wu, Xiufang Liu, Pihai Gong, Wei Song, Menghan Zhou, Yiping Li, Zhujiang Zhao, Hong Fan

Published online on: May 25, 2018
Open Access

Novel triple‑positive markers identified in human non‑small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics

Nazilah Abdul Satar, Kamal Shaik Fakiruddin, Moon Nian Lim, Pooi Ling Mok, Norashikin Zakaria, Noor Atiqah Fakharuzi, Ahmad Zuhairi Abd Rahman, Zubaidah Zakaria, Badrul Hisham Yahaya, Puteri Baharuddin

Published online on: May 24, 2018

Long non‑coding RNA PVT1 promotes epithelial‑mesenchymal transition via the TGF‑β/Smad pathway in pancreatic cancer cells

Xingxing Zhang, Wen Feng, Jin Zhang, Lu Ge, Youli Zhang, Xiaomeng Jiang, Wanxin Peng, Dawei Wang, Aihua Gong, Min Xu

Published online on: May 24, 2018
Open Access

miR‑1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor

Dehua Zhu, Yefei Sun, Danhua Zhang, Ming Dong, Guiyang Jiang, Xiupeng Zhang, Jianping Zhou

Published online on: May 24, 2018

E‑cadherin regulates proliferation of colorectal cancer stem cells through NANOG

Shingo Tamura, Taichi Isobe, Hiroshi Ariyama, Michitaka Nakano, Yoshikane Kikushige, Shigeo Takaishi, Hitoshi Kusaba, Katsuto Takenaka, Takashi Ueki, Masafumi Nakamura, Koichi Akashi, Eishi Baba

Published online on: May 24, 2018
Open Access

MicroRNA‑92a‑3p inhibits the cell proliferation, migration and invasion of Wilms tumor by targeting NOTCH1

Shibo Zhu, Liyu Zhang, Zhang Zhao, Wen Fu, Kai Fu, Guochang Liu, Wei Jia

Published online on: May 23, 2018

RAD52 motif‑containing protein 1 promotes non‑small cell lung cancer cell proliferation and survival via cell cycle regulation

Guihua Xu, Jiya Du, Feng Wang, Fan Zhang, Ruimin Hu, Dejun Sun, Jie Shen

Published online on: May 23, 2018

miR‑218 promotes apoptosis of SW1417 human colon cancer cells by targeting c‑FLIP

Qingkai Meng, Yue Chen, Bo Lian, Yan Shang, Hongmei Yang

Published online on: May 23, 2018

MicroRNA-152 inhibits cell proliferation of osteosarcoma by directly targeting Wnt/β-catenin signaling pathway in a DKK1-dependent manner

Xin Zhao, Shicai Sun, Jianting Xu, Yang Luo, Ying Xin, Yanbing Wang

Published online on: May 22, 2018

Dual mTOR/PI3K inhibitor NVP‑BEZ235 arrests colorectal cancer cell growth and displays differential inhibition of 4E‑BP1

Naif Alqurashi, Saeed M. Hashimi, Faisal Alowaidi, Saso Ivanovski, Ming Q. Wei

Published online on: May 22, 2018

Lysyl oxidase-like 2 is highly expressed in colorectal cancer cells and promotes the development of colorectal cancer

Ximao Cui, Guanghui Wang, Wenbin Shen, Zhenyu Huang, Hailan He, Long Cui

Published online on: May 21, 2018

Luteolin reduces cancer‑induced skeletal and cardiac muscle atrophy in a Lewis lung cancer mouse model

Tiejun Chen, Bin Li, Ye Xu, Shuying Meng, Yuan Wang, Yan Jiang

Published online on: May 21, 2018
Open Access

HSV‑TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK

Quan‑Yong Yi, Zhi‑Sha Bai, Bin Cai, Nan Chen, Li‑Shuang Chen, Tao Yuan, Jing‑Hai Mao

Published online on: May 21, 2018

Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKt inhibitor MK2206 in mammary cancer models

Ronald A. Lubet, Vernon E. Steele, M. M. Juliana, Ann Bode, Fariba Moeinpour, Clinton J. Grubbs

Published online on: March 14, 2018

Evaluation of microRNA-203 in bone metastasis of patients with non-small cell lung cancer through TGF-β/SMAD2 expression

Yucheng Wei, Dongmei Li, Dong Wang, Tong Qiu, Kui Liu

Published online on: September 21, 2017
Journal Cover

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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