Early Online

Autophagy‑mediated adaptation of hepatocellular carcinoma cells to hypoxia‑mimicking conditions constitutes an attractive therapeutic target

Satoshi Owada, Hitoshi Endo, Yukari Shida, Chisa Okada, Kanako Ito, Takahiro Nezu, Masayuki Tatemichi

Published online on: February 23, 2018

Raf1 is a prognostic factor for progression in patients with non‑small cell lung cancer after radiotherapy

Hao  Tian, Li  Yin, Kai  Ding, You‑You  Xia, Xiao‑Hong  Wang, Jian‑Zhong  Wu, Xia He

Published online on: February 22, 2018

Knockdown of end-binding protein 1 induces apoptosis in radioresistant A549 lung cancer cells via p38 kinase-dependent COX-2 upregulation

Jeong-Hwa Baek, Ji-Hye Yim, Jie-Young Song, Hong-Duck Um, Jong Kuk Park, In-Chul Park, Jae-Sung Kim, Chang-Woo Lee, Eun-Hee Hong, Eun Ho Kim, Sang-Gu Hwang

Published online on: February 22, 2018

Knockdown of EPCR inhibits the proliferation and migration of human gastric cancer cells via the ERK1/2 pathway in a PAR-1-dependent manner

Qingling Wang, Hongli Yang, Qian Zhuo, Yanyan Xu, Peng Zhang

Published online on: February 21, 2018

miRNA-320a inhibits glioma cell invasion and migration by directly targeting aquaporin 4

Wei Xiong, Jianhua Ran, Rong Jiang, Pei Guo, Xueping Shi, Haixing Li, Xiaoting Lv, Jing Li, Dilong Chen

Published online on: February 20, 2018

Metformin facilitates BG45‑induced apoptosis via an anti‑Warburg effect in cholangiocarcinoma cells

Dehua Tang, Lei Xu, Mingming Zhang, Robert Gregory Dorfman, Yida Pan, Qian Zhou, Lixing Zhou, Yuming Wang, Yang Li, Yuyao Yin, Lei Wang, Xiaoping Zou

Published online on: February 20, 2018
Open Access

High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer

Yahua Chen, Jun Liu, Wei Wang, Li Xiang, Jide Wang, Side Liu, Hongyan Zhou, Zheng Guo

Published online on: February 16, 2018

High expression of TRAIL by osteoblastic differentiated dental pulp stem cells affects myeloma cell viability

Giacomina Brunetti, Adriana Di Benedetto, Francesca Posa, Graziana Colaianni, Maria Felicia Faienza, Andrea Ballini, Silvia Colucci, Giovanni Passeri, Lorenzo Lo Muzio, Maria Grano, Giorgio Mori

Published online on: February 15, 2018
Open Access

[Corrigendum] Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji

Published online on: February 14, 2018

Prognostic impact of sarcopenia and its correlation with circulating miR-21 in colorectal cancer patients

Yoshinaga Okugawa, Li Yao, Yuji Toiyama, Akira Yamamoto, Tsunehiko Shigemori, Chengzeng Yin, Yusuke Omura, Shozo Ide, Takahito Kitajima, Tadanobu Shimura, Hiroyuki Fujikawa, Hiromi Yasuda, Junichiro Hiro, Shigeyuki Yoshiyama, Minako Kobayashi, Koji Tanaka, Yasuhiro Inoue, Toshimitsu Araki, Chikao Miki, Masato Kusunoki

Published online on: February 14, 2018

Syndecan-1 suppresses epithelial-mesenchymal transition and migration in human oral cancer cells

Xiaofeng Wang, Jinting He, Xiaoming Zhao, Tianyang Qi, Tianfu Zhang, Chenfei Kong

Published online on: February 14, 2018

MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro

Chen-Xing Ji, Yang-Hua Fan, Fan Xu, Shi-Gang Lv, Min-Hua Ye, Miao-Jing Wu, Xin-Gen Zhu, Lei Wu

Published online on: February 13, 2018
Open Access

Effects of low-intensity ultrasound combined with low-dose carboplatin in an orthotopic hamster model of tongue cancer: A preclinical study

Hai-Xia Li, Jin-Hua Zheng, Liang Ji, Guan-Yao Liu, Yv-Kun Lv, Dan Yang, Zheng Hu, He Chen, Feng-Min Zhang, Wenwu Cao

Published online on: February 13, 2018

Differentially expressed circRNAs in melanocytes and melanoma cells and their effect on cell proliferation and invasion

Qi Wang, Jia Chen, Aijun Wang, Lichun Sun, Li Qian, Xiao Zhou, Yu Liu, Shijie Tang, Xiang Chen, Yan Cheng, Ke Cao, Jianda Zhou

Published online on: February 13, 2018

Fatostatin suppresses growth and enhances apoptosis by blocking SREBP-regulated metabolic pathways in endometrial carcinoma

Shuhong Gao, Zhengzheng Shi, Xin Li, Wenzhi Li, Yiling Wang, Zhiming Liu, Jie Jiang

Published online on: February 13, 2018

Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals

Joo-Hung Park, Jeong-Min Lee, Eun-Jin Lee, Da-Jeong Kim, Won-Bhin Hwang

Published online on: February 13, 2018

Combination of salinomycin and radiation effectively eliminates head and neck squamous cell carcinoma cells in vitro

Thomas Gehrke, Stephan Hackenberg, Bülent Polat, Gisela Wohlleben, Rudolf Hagen, Norbert Kleinsasser, Agmal Scherzad

Published online on: February 13, 2018

Mechanism of ECM-induced dormancy and chemoresistance in A549 human lung carcinoma cells

Siriporn Keeratichamroen, Kriengsak Lirdprapamongkol, Jisnuson Svasti

Published online on: February 12, 2018
Open Access

miR-199a-3p enhances cisplatin sensitivity of ovarian cancer cells by targeting ITGB8

Yajie Cui, Fengqin Wu, Defu Tian, Ting Wang, Tianjie Lu, Xiying Huang, Peilian Zhang, Li Qin

Published online on: February 12, 2018
Open Access

Downregulation of the long non-coding RNA XLOC_010588 inhibits the invasion and migration of colorectal cancer

Yue Li, Lin Zhao, Yining Zhang, Lin Guan, Huijing Zhang, Huan Zhou, Tong Gao, Peng Miao, Mingjun Sun

Published online on: February 12, 2018

Vandetanib inhibits cisplatin‑resistant neuroblastoma tumor growth and invasion

Changchun Li, Chao Yang, Guanghui Wei

Published online on: February 9, 2018

Anti-angiogenic and pro-apoptotic effects of a small-molecule JFD-WS in in vitro and breast cancer xenograft mouse models

Appu Rathinavelu, Thanigaivelan Kanagasabai, Sivanesan Dhandayuthapani , Khalid Alhazzani

Published online on: February 9, 2018

Novel structural approaches concerning HPV proteins: Insight into targeted therapies for cervical cancer (Review)

Kalliopi I. Pappa, Georgia Kontostathi, Vasiliki Lygirou, Jerome Zoidakis, Nicholas P. Anagnou

Published online on: February 9, 2018

CXCR4 receptor blockage reduces the contribution of tumor and stromal cells to the metastatic growth in the liver

Aitor Benedicto, Irene Romayor, Beatriz Arteta

Published online on: February 8, 2018

TRIB2 knockdown as a regulator of chemotherapy resistance and proliferation via the ERK/STAT3 signaling pathway in human chronic myelogenous leukemia K562/ADM cells

Xiancheng Ma, Xue Zhou, Haiyan Qu, Ying Ma, Zhen Yue, Wenjing Shang, Pingyu Wang, Shuyang Xie, Youjie Li, Yunxiao Sun

Published online on: February 7, 2018
Open Access

Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy

Hongzhu Yan, Chengmin Qiu, Weiwei Sun, Minmin Gu, Feng Xiao, Jue Zou, Li Zhang

Published online on: February 7, 2018

Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancer

Jin-Wu Chen, Ying-Jia Luo, Zheng-Fei Yang, Li-Qiang Wen, Lin Huang

Published online on: February 7, 2018

Transdifferentiation of type II alveolar epithelial cells induces reactivation of dormant tumor cells by enhancing TGF-β1/SNAI2 signaling

Yuanhong Zhou, Qiang Liu, Xiangchen Dai, Yuling Yan, Ying Yang, Hua Li, Xiaoling Zhou, Wenqi Gao, Xiaolan Li, Zuyang Xi

Published online on: February 6, 2018

Synergistic antitumor effects of histone deacetylase inhibitor scriptaid and bortezomib against ovarian cancer cells

Karolina Janyst, Michał Janyst, Marta Siernicka, Witold Lasek

Published online on: February 6, 2018
Open Access

Long non-coding RNA XIST exerts oncogenic functions in pancreatic cancer via miR-34a-5p

Zhixia Sun, Baogang Zhang, Tingting Cui

Published online on: February 2, 2018

β‑carotene reverses tobacco smoke‑induced gastric EMT via Notch pathway in vivo

Ling Lu, Jia Chen, Manli Li, Ling Tang, Rui Wu, Longtao Jin, Zhaofeng Liang

Published online on: February 2, 2018

Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition

Juan Zhou, Qiaoting Hu, Xi Zhang, Jihua Zheng, Bo Xie, Zhiyong Xu, Weimin Zhang

Published online on: February 1, 2018

β3GnT8 regulates oxaliplatin resistance by altering integrin β1 glycosylation in colon cancer cells

Li Shen, Xiaoxia Dong, Yingying Wang, Li Qiu, Feng Peng, Zhiguo Luo

Published online on: February 1, 2018
Open Access

REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells

Junhong Zhao, Lanlan Geng, Gaoyang Duan, Wanfu Xu, Yang Cheng, Zhiliang Huang, Zhenwen Zhou, Sitang Gong

Published online on: February 1, 2018

Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells

Seiga Ohmine, Jeffrey L. Salisbury, James Ingle, Giuseppe Pettinato, Candace L. Haddox, Tufia Haddad, Evanthia Galanis, Yasuhiro Ikeda, Antonino B. D'assoro

Published online on: January 31, 2018
Open Access

miR-195 inhibits cell proliferation and angiogenesis in human prostate cancer by downregulating PRR11 expression

Chao Cai, Huichan He, Xiaolu Duan, Wenqi Wu, Zanlin Mai, Tao Zhang, Junhong Fan, Tuo Deng, Wen Zhong, Yongda Liu, Weide Zhong, Guohua Zeng

Published online on: January 31, 2018

Tyrphostin B42 attenuates trichostatin A-mediated resistance in pancreatic cancer cells by antagonizing IL-6/JAK2/STAT3 signaling

Xing Zhang, Hong Lu, Weilong Hong, Leping Liu, Silu Wang, Mengtao Zhou, Bicheng Chen, Yongheng Bai

Published online on: January 31, 2018

Puerarin inhibits non-small cell lung cancer cell growth via the induction of apoptosis

Yefang Hu, Xi Li, Ling Lin, Siting Liang, Jian Yan

Published online on: January 26, 2018

TRIM28 promotes cervical cancer growth through the mTOR signaling pathway

Fan Li, Zhijie Wang, Gaochuan Lu

Published online on: January 26, 2018

Synergistic effect of metformin and medroxyprogesterone 17‑acetate on the development of endometrial cancer

Nan Mu, Mei Dong, Lei Li, Min Xia, Luyun Qv, Yingmei Wang, Changyan Dong, Yonghua Chen, Ying Zuo, Jianqing Hou, Fengxia Xue

Published online on: January 26, 2018
Open Access

Short hairpin RNA-mediated gene silencing of ADAM17 inhibits the growth of breast cancer MCF‑7 cells in vitro and in vivo and its mechanism of action

Baoshan Hu, Xiangchao Meng, Yan Zhang, Mohammad Monir Hossain, Lijun Wu, Yuanyuan Zhang, Xiaobing Peng, Xuepeng Zhang

Published online on: January 26, 2018

PARP1-siRNA suppresses human prostate cancer cell growth and progression

Yongchang Lai, Zhenzhen Kong, Tao Zeng, Shaohong Xu, Xiaolu Duan, Shujue Li, Chao Cai, Zhijian Zhao, Wenqi Wu

Published online on: January 26, 2018

Co-treatment with gemcitabine and nab-paclitaxel exerts additive effects on pancreatic cancer cell death

Ilaria Passacantilli, Valentina Panzeri, Francesca Terracciano, Gianfranco Delle Fave, Claudio Sette, Gabriele Capurso

Published online on: January 25, 2018

FNDC3B promotes epithelial-mesenchymal transition in tongue squamous cell carcinoma cells in a hypoxic microenvironment

Zhaoming Zhong, Hongxing Zhang, Min Hong, Chuanzheng Sun, Yuanyuan Xu, Xiao Chen, Change Gao, Minjie He, Weiqing Liu, Jin Liang

Published online on: January 24, 2018

Polygalacin D induces apoptosis and cell cycle arrest via the PI3K/Akt pathway in non-small cell lung cancer

Yun-Soo Seo, Ok-Hwa Kang, Ryong Kong, Tian Zhou, Sang-A Kim, Shiyong Ryu, Hak-Ryul Kim, Dong-Yeul Kwon

Published online on: January 23, 2018
Open Access

Effect of sinomenine hydrochloride on radiosensitivity of esophageal squamous cell carcinoma cells

Shenbo Fu, Long Jin, Tuotuo Gong, Shupei Pan, Shuyu Zheng, Xuanwei Zhang, Tian Yang, Yuchen Sun, Ya Wang, Jia Guo, Beina Hui, Xiaozhi Zhang

Published online on: January 22, 2018

Inhibition of MUS81 improves the chemical sensitivity of olaparib by regulating MCM2 in epithelial ovarian cancer

Ailing Zhong, Hongqin Zhang, Suhong Xie, Minjie Deng, Hui Zheng, Yanchun Wang, Miaomiao Chen, Renquan Lu, Lin Guo

Published online on: January 22, 2018

Evaluation of microRNA-203 in bone metastasis of patients with non-small cell lung cancer through TGF-β/SMAD2 expression

Yucheng Wei, Dongmei Li, Dong Wang, Tong Qiu, Kui Liu

Published online on: September 21, 2017
Journal Cover

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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