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Progress of engineered antibody-targeted molecular imaging for solid tumors (Review)

  • Authors:
    • Hong Zhao
    • Kemi Cui
    • Andrea Muschenborn
    • Stephen T.C. Wong

  • View Affiliations

  • Published online on: January 1, 2008     https://doi.org/10.3892/mmr.1.1.131
  • Pages: 131-134
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

Engineered antibodies, with their high specificity and affinity for their target antigens, as well as their reduced size and multivalent design, can be tailored to carry radionuclide magnetic, luciferase or fluorescent probes for specific attachment to tissue cells, extracellularly or intracellularly, for PET, SPECT, MRI, optical and ultrasonic imaging. The antigen-specific imaging agents of engineered antibodies have deep tissue penetration, high tissue retention and fast blood clearance, which are desirable properties for the rapid imaging of tumors with high specificity and resolution in pre-clinical or clinical imaging studies.

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January-February 2008
Volume 1 Issue 1

Print ISSN: 1791-2997
Online ISSN:1791-3004

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  • Journal Metrics
  • Impact Factor: 3.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 6.9
  • CiteScore Rank: Q2: #98/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.721
  • SCImago Journal Rank (SJR): 0.65
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Spandidos Publications style
Zhao H, Cui K, Muschenborn A and Wong ST: Progress of engineered antibody-targeted molecular imaging for solid tumors (Review). Mol Med Rep 1: 131-134, 2008
APA
Zhao, H., Cui, K., Muschenborn, A., & Wong, S.T. (2008). Progress of engineered antibody-targeted molecular imaging for solid tumors (Review). Molecular Medicine Reports, 1, 131-134. https://doi.org/10.3892/mmr.1.1.131
MLA
Zhao, H., Cui, K., Muschenborn, A., Wong, S. T."Progress of engineered antibody-targeted molecular imaging for solid tumors (Review)". Molecular Medicine Reports 1.1 (2008): 131-134.
Chicago
Zhao, H., Cui, K., Muschenborn, A., Wong, S. T."Progress of engineered antibody-targeted molecular imaging for solid tumors (Review)". Molecular Medicine Reports 1, no. 1 (2008): 131-134. https://doi.org/10.3892/mmr.1.1.131