Journal Articles

MALDI TOF imaging mass spectrometry in clinical pathology: A valuable tool for cancer diagnostics (Review)

Jörg Kriegsmann, Mark Kriegsmann, Rita Casadonte

Pages: 893-906 Published online on: 04 December 2014

Hsp90 inhibitor as a sensitizer of cancer cells to different therapies (Review)

Zuzana Solárová, Ján Mojžiš, Peter Solár

Pages: 907-926 Published online on: 10 December 2014

Identification of dysregulated microRNAs in triple-negative breast cancer (Review)

Fang Yang, Wenwen Zhang, Yan Shen, Xiaoxiang Guan

Pages: 927-932 Published online on: 08 January 2015
Open Access

Role of TGFβ in regulation of the tumor microenvironment and drug delivery (Review)

Panagiotis Papageorgis, Triantafyllos Stylianopoulos

Pages: 933-943 Published online on: 07 January 2015
Open Access

An accurate prognostic staging system for hepatocellular carcinoma patients after curative hepatectomy

Yukio Tokumitsu, Takao Tamesa, Satoshi Matsukuma, Noriaki Hashimoto, Yoshinari Maeda, Yoshihiro Tokuhisa, Kazuhiko Sakamoto, Tomio Ueno, Shoichi Hazama, Hiroyuki Ogihara, Yusuke Fujita, Yoshihiko Hamamoto, Masaaki Oka, Norio Iizuka

Pages: 944-952 Published online on: 17 December 2014
Open Access

Diagnostic value of immunoglobulin κ light chain gene rearrangement analysis in B-cell lymphomas

Ira Kokovic, Barbara Jezersek Novakovic, Srdjan Novakovic

Pages: 953-962 Published online on: 09 December 2014
Open Access

Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells

Naoko Wada, Yawara Kawano, Shiho Fujiwara, Yoshitaka Kikukawa, Yutaka Okuno, Masayoshi Tasaki, Mitsuharu Ueda, Yukio Ando, Kazuya Yoshinaga, Masaki Ri, Shinsuke Iida, Takayuki Nakashima, Yukimasa Shiotsu, Hiroaki Mitsuya, Hiroyuki Hata

Pages: 963-972 Published online on: 19 December 2014
Open Access

Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang

Pages: 981-988 Published online on: 08 January 2015
Open Access

Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: Retrospective and in vitro studies

Hiroki Izumi, Hirokazu Touge, Tadashi Igishi, Haruhiko Makino, Shizuka Nishii‑Ito, Miyako Takata, Hirofumi Nakazaki, Yasuto Ueda, Shingo Matsumoto, Masahiro Kodani, Jun Kurai, Kenichi Takeda, Tomohiro Sakamoto, Masaaki Yanai, Natsumi Tanaka, Chaitanya S. Nirodi, Eiji Shimizu

Pages: 989-998 Published online on: 07 January 2015
Open Access

FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma

Naoyuki Okabe, Junji Ezaki, Takumi Yamaura, Satoshi Muto, Jun Osugi, Hirosumi Tamura, Jun‑Ichi Imai, Emi Ito, Yuka Yanagisawa, Reiko Honma, Mitsukazu Gotoh, Shinya Watanabe, Satoshi Waguri, Hiroyuki Suzuki

Pages: 999-1006 Published online on: 07 January 2015

Gastric cancer cell proliferation is suppressed by frizzled-2 short hairpin RNA

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Pages: 1018-1024 Published online on: 09 January 2015

Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer

Akihiro Kogita, Yosuke Togashi, Hidetoshi Hayashi, Eri Banno, Masato Terashima, Marco A. De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yoshifumi Takeyama, Kiyotaka Okuno, Kazuhiko Nakagawa, Kazuto Nishio

Pages: 1025-1030 Published online on: 15 December 2014

Overexpression of miR‑145 in U87 cells reduces glioma cell malignant phenotype and promotes survival after in vivo implantation

Yong Lu, Michael Chopp, Xuguang Zheng, Mark Katakowski, Ding Wang, Elise Fraser, Monique Nguyen, Feng Jiang

Pages: 1031-1038 Published online on: 23 December 2014

Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma

Hiroko Mataki, Naohiko Seki, Takeshi Chiyomaru, Hideki Enokida, Yusuke Goto, Tomohiro Kumamoto, Kentaro Machida, Keiko Mizuno, Masayuki Nakagawa, Hiromasa Inoue

Pages: 1039-1050 Published online on: 18 December 2014

Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells

Shaobo Ke, Fuxiang Zhou, Hui Yang, Yuehua Wei, Jun Gong, Zijie Mei, Lin Wu, Haijun Yu, Yunfeng Zhou

Pages: 1051-1058 Published online on: 10 December 2014

Usefulness of microRNA‑375 as a prognostic and therapeutic tool in esophageal squamous cell carcinoma

Yuka Isozaki, Isamu Hoshino, Yasunori Akutsu, Naoyuki Hanari, Mikito Mori, Takanori Nishimori, Kentaro Murakami, Naoki Akanuma, Nobuyoshi Takeshita, Tetsuro Maruyama, Takeshi Toyozumi, Masahiko Takahashi, Hiroshi Suito, Hisahiro Matsubara

Pages: 1059-1066 Published online on: 09 December 2014

Arsenic trioxide-induced cytotoxicity in small cell lung cancer via altered redox homeostasis and mitochondrial integrity

Chun-Yan Zheng, Sze-Kwan Lam, Yuan-Yuan Li, James Chung-Man Ho

Pages: 1067-1078 Published online on: 09 January 2015

Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivity

Timothy D. Rohrbach, John S. Jarboe, Joshua C. Anderson, Hoa Q. Trummell, Patricia H. Hicks, Alice N. Weaver, Eddy S. Yang, Robert A. Oster, Jessy S. Deshane, Chad Steele, Gene P. Siegal, James A. Bonner, Christopher D. Willey

Pages: 1079-1088 Published online on: 17 December 2014

Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma

Tri Budi Hartomo, Thi Van Huyen Pham, Nobuyuki Yamamoto, Satoshi Hirase, Daiichiro Hasegawa, Yoshiyuki Kosaka, Masafumi Matsuo, Akira Hayakawa, Yasuhiro Takeshima, Kazumoto Iijima, Hisahide Nishio, Noriyuki Nishimura

Pages: 1089-1098 Published online on: 17 December 2014

Pancreatic ductal adenocarcinoma cell lines display a plastic ability to bi‑directionally convert into cancer stem cells

Elisa Dalla Pozza, Ilaria Dando, Giulia Biondani, Jessica Brandi, Chiara Costanzo, Elisa Zoratti, Matteo Fassan, Federico Boschi, Davide Melisi, Daniela Cecconi, Maria Teresa Scupoli, Aldo Scarpa, Marta Palmieri

Pages: 1099-1108 Published online on: 12 December 2014

CCL18 promotes epithelial-mesenchymal transition, invasion and migration of pancreatic cancer cells in pancreatic ductal adenocarcinoma

Fanbin Meng, Wan Li, Changling Li, Zhigang Gao, Kejian Guo, Shaowei Song

Pages: 1109-1120 Published online on: 10 December 2014

Parthenolide enhances sensitivity of colorectal cancer cells to TRAIL by inducing death receptor 5 and promotes TRAIL-induced apoptosis

Se-Lim Kim, Yu-Chuan Liu, Young Ran Park, Seung Young Seo, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Dae-Ghon Kim, Sang-Wook Kim

Pages: 1121-1130 Published online on: 12 December 2014

Genistein exerts growth inhibition on human osteosarcoma MG-63 cells via PPARγ pathway

Mingzhi Song, Xiliang Tian, Ming Lu, Xianbin Zhang, Kai Ma, Zhichao Lv, Zhenxing Wang, Yang Hu, Chong Xun, Zhen Zhang, Shouyu Wang

Pages: 1131-1140 Published online on: 09 January 2015

Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role

Xiaojin Zhang, Xiaoai Zhao, Shan Shao, Xiaoxiao Zuo, Qian Ning, Minna Luo, Shanzhi Gu, Xinhan Zhao

Pages: 1141-1148 Published online on: 23 December 2014

Luteolin acts as a radiosensitizer in non‑small cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade

Hyun‑Ji Cho, Kwang‑Chul Ahn, Jae Yeon Choi, Sang‑Gu Hwang, Wun‑Jae Kim, Hong‑Duck Um, Jong Kuk Park

Pages: 1149-1158 Published online on: 09 January 2015

Evaluation of a 64Cu‑labeled 1,4,7‑triazacyclononane, 1‑glutaric acid‑4,7 acetic acid (NODAGA)‑galactose‑bombesin analogue as a PET imaging probe in a gastrin‑releasing peptide receptor‑expressing prostate cancer xenograft model

Min Hwan Kim, Ji Ae Park, Sang‑Keun Woo, Kyo Chul Lee, Gwang Il An, Byoung Soo Kim, Kwang Il Kim, Tae Sup Lee, Chan Wha Kim, Kyeong Min Kim, Joo Hyun Kang, Yong Jin Lee

Pages: 1159-1168 Published online on: 09 January 2015

miR-221-induced PUMA silencing mediates immune evasion of bladder cancer cells

Bin Fu, Yibing Wang, Xiali Zhang, Bin Lang, Xiaocheng Zhou, Xiaoyuan Xu, Tao Zeng, Weipeng Liu, Xu Zhang, Ju Guo, Gongxian Wang

Pages: 1169-1180 Published online on: 13 January 2015

Mathematical analysis predicts imbalanced IDH1/2 expression associates with 2-HG-inactivating β-oxygenation pathway in colorectal cancer

Jun Koseki, Hugh Colvin, Takahito Fukusumi, Naohiro Nishida, Masamitsu Konno, Koichi Kawamoto, Kenta Tsunekuni, Hidetoshi Matsui, Yuichiro Doki, Masaki Mori, Hideshi Ishii

Pages: 1181-1191 Published online on: 12 January 2015

5-Azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation

Mathias Füller, Miriam Klein, Eva Schmidt, Christian Rohde, Stefanie Göllner, Isabell Schulze, Jiang Qianli, Wolfgang E. Berdel, Bayram Edemir, Carsten Müller-Tidow, Petra Tschanter

Pages: 1192-1204 Published online on: 10 December 2014

The role of IGFBP-5 in mediating the anti-proliferation effect of tetrandrine in human colon cancer cells

Ke Wu, Mi Zhou, Qiu-Xiang Wu, Shuang-Xu Yuan, Dong-Xu Wang, Jie-Li Jin, Jun Huang, Jun-Qin Yang, Wen-Juan Sun, Li-Hua Wan, Bai-Cheng He

Pages: 1205-1213 Published online on: 17 December 2014

The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells

Antonia Bellizzi, Maria Raffaella Greco, Rosa Rubino, Angelo Paradiso, Stefania Forciniti, Katrine Zeeberg, Rosa Angela Cardone, Stephan Joel Reshkin

Pages: 1214-1224 Published online on: 19 December 2014

Anti-metastasis efficacy and safety of non-anticoagulant heparin derivative versus low molecular weight heparin in surgical pancreatic cancer models

Reem Alyahya, Thangirala Sudha, Michael Racz, Steven C. Stain, Shaker A. Mousa

Pages: 1225-1231 Published online on: 19 December 2014

Downregulation of UHRF1 promotes EMT via inducing CXCR4 in human cancer cells

Yi-Deun Jung, Jae-Woong Shim, Seong-Joon Park, Si Ho Choi, Kwangmo Yang, Kyu Heo, Moon-Taek Park

Pages: 1232-1242 Published online on: 30 December 2014

CHST11 gene expression and DNA methylation in breast cancer

Damir Herman, Tatiana I. Leakey, Alice Behrens, Aiwei Yao-Borengasser, Craig A. Cooney, Fariba Jousheghany, Bounleut Phanavanh, Eric R. Siegel, A. Mazin Safar, Soheila Korourian, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Pages: 1243-1251 Published online on: 09 January 2015

Decreased expression of carbonyl reductase 1 promotes ovarian cancer growth and proliferation

Yuki Osawa, Yoshihito Yokoyama, Tatsuhiko Shigeto, Masayuki Futagami, Hideki Mizunuma

Pages: 1252-1258 Published online on: 30 December 2014

Relationship between in vitro drug sensitivity and clinical response of patients to treatment in chronic lymphocytic leukemia

Małgorzata Rogalińska, Jerzy Z. Błoński, Paweł Góralski, Ewa Wawrzyniak, Mariusz Hartman, Aneta Rogalska, Paweł Robak, Aneta Koceva‑Chyła, Henryk Piekarski, Tadeusz Robak, Zofia M. Kiliańska

Pages: 1259-1267 Published online on: 08 January 2015

A cisplatin‑incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity

Joohee Jung, Seong‑Yun Jeong, Seok Soon Park, Seol Hwa Shin, Eun Jin Ju, Jinhyang Choi, Jaesook Park, Jae Hee Lee, Inki Kim, Young‑Ah Suh, Jung Jin Hwang, Shun'ichi Kuroda, Jung Shin Lee, Si Yeol Song, Eun Kyung Choi

Pages: 1268-1274 Published online on: 22 December 2014

Glypican-3 promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells through ERK signaling pathway

Yongle Wu, Hui Liu, Honglei Weng, Xin Zhang, Peng Li, Chun-Lei Fan, Bing Li, Pei-Ling Dong, Lei Li, Steven Dooley, Hui-Guo Ding

Pages: 1275-1285 Published online on: 09 January 2015

Autophagy facilitates the development of resistance to the tumor necrosis factor superfamily member TRAIL in breast cancer

Shangge Lv, Xiaolong Wang, Ning Zhang, Mingjuan Sun, Wenwen Qi, Yaming Li, Qifeng Yang

Pages: 1286-1294 Published online on: 30 December 2014

Adenovirus-mediated ING4/PTEN double tumor suppressor gene co-transfer modified by RGD enhances antitumor activity in human nasopharyngeal carcinoma cells

Yihong Wang, Jicheng Yang, Weihua Sheng, Yufeng Xie, Jisheng Liu

Pages: 1295-1303 Published online on: 08 January 2015

Bcl2L12 with a BH3-like domain in regulating apoptosis and TMZ-induced autophagy: A prospective combination of ABT-737 and TMZ for treating glioma

Ming-Chang Yang, Joon-Khim Loh, Yi-Yang Li, Wen-Sheng Huang, Chia-Hua Chou, Jiin-Tsuey Cheng, Yeng-Tseng Wang, Ann-Shung Lieu, Shen-Long Howng, Yi-Ren Hong, An-Kuo Chou

Pages: 1304-1316 Published online on: 13 January 2015

Silencing HO-1 sensitizes SKM-1 cells to apoptosis induced by low concentration 5-azacytidine through enhancing p16 demethylation

Ping Wang, Dan Ma, Jishi Wang, Qin Fang, Rui Gao, Weibing Wu, Tangsheng Lu, Lu Cao

Pages: 1317-1327 Published online on: 12 January 2015

Overexpression of PGC‑1α enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein

Sung-Won Shin, Seong-Hoon Yun, Eun-Seon Park, Jin-Sook Jeong, Jong-Young Kwak, Joo-In Park

Pages: 1328-1342 Published online on: 12 January 2015

Rac1 is correlated with aggressiveness and a potential therapeutic target for gastric cancer

Jun Ji, Xiaojing Feng, Min Shi, Qu Cai, Yingyan Yu, Zhenggang Zhu, Jun Zhang

Pages: 1343-1353 Published online on: 13 January 2015

LH-RH analogues in the treatment of young women with early breast cancer: Long-term follow-up of a phase II study

Francesco Recchia, Stefano Necozione, Massimo Bratta, Michele Rosselli, Gabriele Guerriero, Silvio Rea

Pages: 1354-1360 Published online on: 30 December 2014

Importance of circulating tumor cells in newly diagnosed colorectal cancer

Guus van Dalum, Gerrit-Jan Stam, Loes F.A. Scholten, Walter J.B. Mastboom, Istvan Vermes, Arjan G.J. Tibbe, Marco R. De Groot, Leon W.M.M. Terstappen

Pages: 1361-1368 Published online on: 09 January 2015

The tryptophan derivative, tranilast, and conditioned medium with indoleamine 2,3-dioxygenase-expressing cells inhibit the proliferation of lymphoid malignancies

Shihoko Suwa, Aya Kasubata, Miyu Kato, Megumi Iida, Ken Watanabe, Osamu Miura, Tetsuya Fukuda

Pages: 1369-1376 Published online on: 09 January 2015

SIAH1-induced p34SEI-1 polyubiquitination/degradation mediates p53 preferential vitamin C cytotoxicity

Soonduck Lee, Jinsun Kim, Samil Jung, Chengping Li, Young Yang, Keun Il Kim, Jong-Seok Lim, Yonghwan Kim, Choong-Il Cheon, Myeong-Sok Lee

Pages: 1377-1384 Published online on: 13 January 2015

Licochalcone A induces apoptosis in malignant pleural mesothelioma through downregulation of Sp1 and subsequent activation of mitochondria-related apoptotic pathway

Ka Hwi Kim, Goo Yoon, Jung Jae Cho, Jin Hyoung Cho, Young Sik Cho, Jung-Il Chae, Jung-Hyun Shim

Pages: 1385-1392 Published online on: 13 January 2015

Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanisms

Dai Tamura, Teruyoshi Saito, Kanae Murata, Masafumi Kawashima, Ryuji Asano

Pages: 1393-1404 Published online on: 08 January 2015

Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells

Young-Ah Suh, Se-Young Jo, Hwa-Young Lee, Chuhee Lee

Pages: 1405-1411 Published online on: 23 December 2014
Journal Cover

Cover Legend PDF

March 2015
Volume 46 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2013 Impact Factor: 2.773
Ranked #30/202 Oncology
(total number of cites)

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