Chemoenzymatic preparation of intermediates for the taxol side chain and analogs
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- Published online on: March 1, 2010 https://doi.org/10.3892/mmr_00000258
- Pages: 317-318
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Abstract
In the present study, optically active cis and trans α-hydroxy-β-lactams were prepared by Baker's yeast reduction of a racemic α-keto-β-lactam and by the hydrolysis of a racemic α-acetoxy β-lactam with the resting cells of Bacillus Subtilis.
