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Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer.

  • Authors:
    • H Tomoda
    • H Baba
    • A Taketomi
    • S Kohnoe
    • Y Seo
    • T Saito

  • View Affiliations

  • Published online on: January 1, 1998     https://doi.org/10.3892/or.5.1.143
  • Pages: 143-148
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Abstract

We examined the occurrence of second primary extracolonic cancers in 1,170 patients with nonpolyposis colorectal cancer who underwent a resection between 1972 and 1994. Such cancers occurred more often in cases with hereditary nonpolyposis colorectal cancer (HNPCC) than in those without (11.1% vs. 3.6%, P=0.0286). Five HNPCC cases developed 6 cancers in the stomach, endometrium, ovary, and ureter. The mean interval between the first and second operation was 66 months (range: 18-153). These findings thus indicate the importance of targetted surveillance for any second primary cancers in the upper gastrointestinal, female genital, or upper urologic tract, especially in HNPCC patients.

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Jan-Feb 1998
Volume 5 Issue 1

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Spandidos Publications style
Tomoda H, Baba H, Taketomi A, Kohnoe S, Seo Y and Saito T: Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer.. Oncol Rep 5: 143-148, 1998
APA
Tomoda, H., Baba, H., Taketomi, A., Kohnoe, S., Seo, Y., & Saito, T. (1998). Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer.. Oncology Reports, 5, 143-148. https://doi.org/10.3892/or.5.1.143
MLA
Tomoda, H., Baba, H., Taketomi, A., Kohnoe, S., Seo, Y., Saito, T."Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer.". Oncology Reports 5.1 (1998): 143-148.
Chicago
Tomoda, H., Baba, H., Taketomi, A., Kohnoe, S., Seo, Y., Saito, T."Second primary extracolonic cancers in Japanese hereditary nonpolyposis colorectal cancer.". Oncology Reports 5, no. 1 (1998): 143-148. https://doi.org/10.3892/or.5.1.143