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Honokiol induces apoptosis in human lymphoid leukemia Molt 4B cells.

  • Authors:
    • H Hibasami
    • Y Achiwa
    • H Katsuzaki
    • K Imai
    • K Yoshioka
    • K Nakanishi
    • Y Ishii
    • M Hasegawa
    • T Komiya

  • View Affiliations

  • Published online on: December 1, 1998     https://doi.org/10.3892/ijmm.2.6.671
  • Pages: 671-674
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

The exposure of human lymphoid leukemia Molt 4B cells to honokiol led to both growth inhibition and the induction of apoptosis. Morphological change showing apoptotic bodies was observed in the cells treated with honokiol. The fragmentation by honokiol of DNA to oligonucleosomal-sized fragments that are characteristics of apoptosis was observed to be concentration- and time-dependent. These findings suggest that growth inhibition by honokiol of Molt 4B cells results from the induction of apoptosis in the cells.

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Dec 1998
Volume 2 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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  • Journal Metrics
  • Impact Factor: 5.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 10.7
  • CiteScore Rank: Q1: #35/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.994
  • SCImago Journal Rank (SJR): 0.922
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Spandidos Publications style
Hibasami H, Achiwa Y, Katsuzaki H, Imai K, Yoshioka K, Nakanishi K, Ishii Y, Hasegawa M and Komiya T: Honokiol induces apoptosis in human lymphoid leukemia Molt 4B cells.. Int J Mol Med 2: 671-674, 1998
APA
Hibasami, H., Achiwa, Y., Katsuzaki, H., Imai, K., Yoshioka, K., Nakanishi, K. ... Komiya, T. (1998). Honokiol induces apoptosis in human lymphoid leukemia Molt 4B cells.. International Journal of Molecular Medicine, 2, 671-674. https://doi.org/10.3892/ijmm.2.6.671
MLA
Hibasami, H., Achiwa, Y., Katsuzaki, H., Imai, K., Yoshioka, K., Nakanishi, K., Ishii, Y., Hasegawa, M., Komiya, T."Honokiol induces apoptosis in human lymphoid leukemia Molt 4B cells.". International Journal of Molecular Medicine 2.6 (1998): 671-674.
Chicago
Hibasami, H., Achiwa, Y., Katsuzaki, H., Imai, K., Yoshioka, K., Nakanishi, K., Ishii, Y., Hasegawa, M., Komiya, T."Honokiol induces apoptosis in human lymphoid leukemia Molt 4B cells.". International Journal of Molecular Medicine 2, no. 6 (1998): 671-674. https://doi.org/10.3892/ijmm.2.6.671