Journal Articles

Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (Review)

Camilla Evangelisti, Cecilia Evangelisti, Francesca Chiarini, Annalisa Lonetti, Francesca Buontempo, Daniela Bressanin, Alessandra Cappellini, Ester Orsini, James A. McCubrey, Alberto M. Martelli

Pages: 909-918 Published online on: 26 June 2014

Emerging targets to monitor and overcome docetaxel resistance in castration resistant prostate cancer (Review)

L. Magadoux, N. Isambert, S. Plenchette, J. F. Jeannin, V. Laurens

Pages: 919-928 Published online on: 24 June 2014
Open Access

Towards combinatorial targeted therapy in melanoma: From pre-clinical evidence to clinical application (Review)

Giulia Grazia, Ilaria Penna, Valentina Perotti, Andrea Anichini, Elena Tassi

Pages: 929-949 Published online on: 10 June 2014

MicroRNAs in the diagnosis and prognosis of breast cancer and their therapeutic potential (Review)

Kaiyuan Zhang, Yanlei Zhang, Chang Liu, Ying Xiong, Jiqiang Zhang

Pages: 950-958 Published online on: 10 June 2014
Open Access

Inflammatory cues acting on the adult intestinal stem cells and the early onset of cancer (Review)

A. De Lerma Barbaro, G. Perletti, I. M. Bonapace, E. Monti

Pages: 959-968 Published online on: 10 June 2014

TRAP1 revisited: Novel localizations and functions of a ‘next-generation’ biomarker (Review)

Maria Rosaria Amoroso, Danilo Swann Matassa, Lorenza Sisinni, Giacomo Lettini, Matteo Landriscina, Franca Esposito

Pages: 969-977 Published online on: 27 June 2014
Open Access

Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells

Zhongyun Dong, Jaroslaw Meller, Paul Succop, Jiang Wang, Kathryn Wikenheiser-Brokamp, Sandra Starnes, Shan Lu

Pages: 978-984 Published online on: 10 June 2014
Open Access

Functional characteristics of cancer stem cells and their role in drug resistance of prostate cancer

Viviana Castillo, Rodrigo Valenzuela, Christian Huidobro, Hector R. Contreras, Enrique A. Castellon

Pages: 985-994 Published online on: 27 June 2014
Open Access

Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-κB in vitro and in vivo

Weiwei Tang, Guangjian Su, Jieyu Li, Jinrong Liao, Shuping Chen, Chuanzhong Huang, Fang Liu, Qiang Chen, Yunbin Ye

Pages: 995-1010 Published online on: 23 June 2014
Open Access

Induction of apoptosis by a peptide from Porphyra yezoensis: Regulation of the insulin-like growth factor I receptor signaling pathway in MCF-7 cells

Su-Jin Park, Jina Ryu, In-Hye Kim, Youn-Hee Choi, Taek-Jeong Nam

Pages: 1011-1016 Published online on: 20 June 2014
Open Access

Prediction of concurrent chemoradiotherapy outcome in advanced oropharyngeal cancer

Masahiro Hasegawa, Hiroyuki Maeda, Zeyi Deng, Asanori Kiyuna, Akira Ganaha, Yukashi Yamashita, Sen Matayoshi, Shinya Agena, Takafumi Toita, Takayuki Uehara, Mikio Suzuki

Pages: 1017-1026 Published online on: 18 June 2014
Open Access

NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells

Du G. Moon, Sang E. Lee, Mi M. Oh, Sang C. Lee, Seong J. Jeong, Sung K. Hong, Cheol Y. Yoon, Seok S. Byun, Hong S. Park, Jun Cheon

Pages: 1027-1035 Published online on: 19 June 2014

Protein kinase C ζ regulates survivin expression and inhibits apoptosis in colon cancer

Yoshifumi Umemori, Kageaki Kuribayashi, Shinya Nirasawa, Takashi Kondoh, Maki Tanaka, Daisuke Kobayashi, Naoki Watanabe

Pages: 1043-1050 Published online on: 10 June 2014

Association between ephrin-A1 mRNA expression and poor prognosis after hepatectomy to treat hepatocellular carcinoma

Hiroshi Wada, Hirofumi Yamamoto, Chiwan Kim, Mamoru Uemura, Hirofumi Akita, Yoshito Tomimaru, Naoki Hama, Koichi Kawamoto, Shogo Kobayashi, Hidetoshi Eguchi, Koji Umeshita, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

Pages: 1051-1058 Published online on: 24 June 2014

Human β-defensin-3 inhibits migration of colon cancer cells via downregulation of metastasis-associated 1 family, member 2 expression

Satoko Uraki, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Yuji Inagaki, Suguru Ogura, Chika Kasai, Keiichiro Nojiri, Misao Yoneda, Norihiko Yamamoto, Yoshiyuki Takei, Tsutomu Nobori, Masaaki Ito

Pages: 1059-1064 Published online on: 20 June 2014

Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE‑cadherin/EphA2/MMP9/MMP2 expression

Jing-Qiang Guo, Qing-Hui Zheng, Hui Chen, Liang Chen, Jin-Bo Xu, Min-Yuan Chen, Dian Lu, Zhao-Hong Wang, Hong-Fei Tong, Shengzhang Lin

Pages: 1065-1072 Published online on: 16 June 2014

CD7 promotes extramedullary involvement of the B-cell acute lymphoblastic leukemia line Tanoue by enhancing integrin β2-dependent cell adhesiveness

Takashi Kondoh, Kageaki Kuribayashi, Maki Tanaka, Daisuke Kobayashi, Nozomi Yanagihara, Naoki Watanabe

Pages: 1073-1081 Published online on: 11 June 2014

Clinical significance of early interventional therapy of branched-chain amino acid granules in patients with hepatocellular carcinoma: Propensity score matching analysis

Hiroki Nishikawa, Ryuichi Kita, Toru Kimura, Yoshiaki Ohara, Haruhiko Takeda, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Yukio Osaki

Pages: 1082-1090 Published online on: 24 June 2014

Association of EMP1 with gastric carcinoma invasion, survival and prognosis

Guogui Sun, Gang Zhao, Yifang Lu, Yadi Wang, Congrong Yang

Pages: 1091-1098 Published online on: 10 June 2014

Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy

Jin-Hua He, Xiao-Li Liao, Wei Wang, Dan-Dan Li, Wen-Dan Chen, Rong Deng, Dajun Yang, Ze-Ping Han, Jian-Wei Jiang, Xiao-Feng Zhu

Pages: 1099-1108 Published online on: 11 June 2014

The combined treatment with chloroquine and the enzymatic oxidation products of spermine overcomes multidrug resistance of melanoma M14 ADR2 cells: A new therapeutic approach

Enzo Agostinelli, Maria Condello, Giampiero Tempera, Alberto Macone, Giuseppina Bozzuto, Shinji Ohkubo, Annarica Calcabrini, Giuseppe Arancia, Agnese Molinari

Pages: 1109-1122 Published online on: 18 June 2014

Intestinal trefoil factor activates the PI3K/Akt signaling pathway to protect gastric mucosal epithelium from damage

Zhaorui Sun, Hongmei Liu, Zhizhou Yang, Danbing Shao, Wei Zhang, Yi Ren, Baodi Sun, Jinfeng Lin, Min Xu, Shinan Nie

Pages: 1123-1132 Published online on: 27 June 2014

Identification of differentially expressed genes and their subpathways in recurrent versus primary bone giant cell tumors

Shuxin Chen, Chunquan Li, Bingli Wu, Chunlong Zhang, Cheng Liu, Xiaoxu Lin, Xiangqiao Wu, Lingling Sun, Chunpeng Liu, Bo Chen, Zhigang Zhong, Liyan Xu, Enmin Li

Pages: 1133-1142 Published online on: 18 June 2014

The co-localization of HBx and COXIII upregulates COX-2 promoting HepG2 cell growth

Bi-Yun Zheng, Xue-Fen Fang, Lai-Yu Zou, Yue-Hong Huang, Zhi-Xin Chen, Dan Li, Lin-Ying Zhou, Hao Chen, Xiao-Zhong Wang

Pages: 1143-1150 Published online on: 16 June 2014

Interference of Ca2+ with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells

Anna Otte, Finn Rauprich, Juliane von der Ohe, Peter Hillemanns, Ralf Hass

Pages: 1151-1158 Published online on: 24 June 2014

Association between cellular radiosensitivity and G1/G2 checkpoint proficiencies in human cholangiocarcinoma cell lines

Arunee Hematulin, Daniel Sagan, Kanlayanee Sawanyawisuth, Wunchana Seubwai, Sopit Wongkham

Pages: 1159-1166 Published online on: 24 June 2014

Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations

Sandy Chevrier, Laurent Arnould, François Ghiringhelli, Bruno Coudert, Pierre Fumoleau, Romain Boidot

Pages: 1167-1174 Published online on: 27 June 2014

Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng

Pages: 1175-1183 Published online on: 13 June 2014

Overexpression of Yin Yang 1 in bone marrow-derived human multiple myeloma and its clinical significance

Sara Huerta-Yepez, Hong Liu, Stavroula Baritaki, Maria Del Lourdes Cebrera‑Muñoz, Clara Rivera-Pazos, Altagracia Maldonado-Valenzuela, Alberto Valencia-Hipolito, Mario I. Vega, Haiming Chen, James R. Berenson, Benjamin Bonavida

Pages: 1184-1192 Published online on: 20 June 2014

Inhibition of Cdk2 kinase activity selectively targets the CD44+/CD24-/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells

Mateusz Opyrchal, Jeffrey L. Salisbury, Ianko Iankov, Mathew P. Goetz, James McCubrey, Mario W. Gambino, Lorenzo Malatino, Giuseppe Puccia, James N. Ingle, Evanthia Galanis, Antonino B. D'Assoro

Pages: 1193-1199 Published online on: 25 June 2014

Microarray analysis of gene expression by microdissected epidermis and dermis in mycosis fungoides and adult T-cell leukemia/lymphoma

Keiko Hashikawa, Shinichiro Yasumoto, Kazutaka Nakashima, Fumiko Arakawa, Junichi Kiyasu, Yoshizo Kimura, Hiroshi Saruta, Takekuni Nakama, Kaori Yasuda, Kosuke Tashiro, Satoru Kuhara, Takashi Hashimoto, Koichi Ohshima

Pages: 1200-1208 Published online on: 26 June 2014

Buccal microRNA dysregulation in lung field carcinogenesis: Gender-specific implications

Ramesh K. Wali, Thomas A. Hensing, Daniel W. Ray, Mart Dela Cruz, Ashish K. Tiwari, Andrew Radosevich, Lisa Jepeal, Hiran C. Fernando, Virginia R. Litle, Marjory Charlot, Navneet Momi, Vadim Backman, Hemant K. Roy

Pages: 1209-1215 Published online on: 11 June 2014

Knockdown of hTERT by siRNA inhibits cervical cancer cell growth in vitro and in vivo

Ying-Ai Shi, Qiang Zhao, Li-Hong Zhang, Wei Du, Xue-Yao Wang, Xu He, Shan Wu, Yu-Lin Li

Pages: 1216-1224 Published online on: 11 June 2014

MicroRNA-124 regulates TGF-α-induced epithelial-mesenchymal transition in human prostate cancer cells

Wei Qin, Yujia Pan, Xiulan Zheng, Dong Li, Jingyi Bu, Chunyan Xu, Jiebing Tang, Rongjun Cui, Ping Lin, Xiaoguang Yu

Pages: 1225-1231 Published online on: 19 June 2014

Sine oculis homeobox homolog 1 promotes DNA replication and cell proliferation in cervical cancer

Dan Liu, Xiao-Xue Zhang, Bi-Xin Xi, Dong-Yi Wan, Li Li, Jin Zhou, Wei Wang, Ding Ma, Hui Wang, Qing-Lei Gao

Pages: 1232-1240 Published online on: 20 June 2014

Knockdown of IGF2R suppresses proliferation and induces apoptosis in hemangioma cells in vitro and in vivo

J. -M. Ou, W. -S. Lian, M. -K. Qiu, Y. -X. Dai, Q. Dong, J. Shen, P. Dong, X. -F. Wang, Y. -B. Liu, Z. -W. Quan, Z. -W. Fei

Pages: 1241-1249 Published online on: 23 June 2014

Anti-inflammatory effects of betaine on AOM/DSS‑induced colon tumorigenesis in ICR male mice

Dong Hwan Kim, Bokyung Sung, Yong Jung Kang, Jung Yoon Jang, Seong Yeon Hwang, Yujin Lee, Minjung Kim, Eunok Im, Jeong-Hyun Yoon, Cheol Min Kim, Hae Young Chung, Nam Deuk Kim

Pages: 1250-1256 Published online on: 24 June 2014

miR-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2

Li Ying Liu, Wei Wang, Lin Yu Zhao, Bo Guo, Juan Yang, Xiao Ge Zhao, Ni Hou, Lei Ni, Ai Ying Wang, Tu Sheng Song, Chen Huang, Ji Ru Xu

Pages: 1257-1265 Published online on: 24 June 2014

Downregulation of NEK11 is associated with drug resistance in ovarian cancer

Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin

Pages: 1266-1274 Published online on: 18 June 2014

Epigenetic alterations are involved in the overexpression of glutathione S-transferase π-1 in human colorectal cancers

Rui Zhang, Kyoung Ah Kang, Mei Jing Piao, Ki Cheon Kim, Jian Zheng, Cheng Wen Yao, Ji Won Cha, Young Hee Maeng, Weon Young Chang, Pyong-Gon Moon, Moon-Chang Baek, Jin Won Hyun

Pages: 1275-1283 Published online on: 25 June 2014

Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients

Caroline Staff, Fariba Mozaffari, Jan-Erik Frödin, Håkan Mellstedt, Maria Liljefors

Pages: 1293-1303 Published online on: 11 June 2014

Tumour angiogenesis and repulsive guidance molecule b: A role in HGF- and BMP-7-mediated angiogenesis

Andrew J. Sanders, Lin Ye, Jin Li, Malcolm D. Mason, Wen G. Jiang

Pages: 1304-1312 Published online on: 20 June 2014

Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer

Jiaxing Yang, Lin Zhu, Yong Cai, Jian Suo, Jingji Jin

Pages: 1313-1320 Published online on: 11 June 2014
Journal Cover

Cover Legend PDF

September 2014
Volume 45 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2012 Impact Factor: 2.657
Ranked #31/196 Oncology
(total number of cites)

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