Journal Articles

The gonadotropin-releasing hormone system: Perspectives from reproduction to cancer (Review)

Arturo Aguilar-Rojas, Marco Allan Pérez-Solis, Guadalupe Maya-Núñez

Pages: 861-868 Published online on: 19 January 2016
Open Access

Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

George Mihai Nitulescu, Denisa Margina, Petras Juzenas, Qian Peng, Octavian Tudorel Olaru, Emmanouil Saloustros, Concettina Fenga, Demetrios Α. Spandidos, Massimo Libra, Aristidis M. Tsatsakis

Pages: 869-885 Published online on: 24 December 2015

Involvement of F-box proteins in esophageal cancer (Review)

Jian Gong, Zheng Huang, Ji-Rong Huo

Pages: 886-894 Published online on: 05 January 2016

Personalization of the medical treatment of solid tumours using patient-derived tumour explants (Review)

Christophe Louandre, Jérome Donnadieu, Emma Lachaier, Cyril Page, Bruno Chauffert, Antoine Galmiche

Pages: 895-899 Published online on: 18 January 2016

The clinical utility of CA125/MUC16 in pancreatic cancer: A consensus of diagnostic, prognostic and predictive updates by the Chinese Study Group for Pancreatic Cancer (CSPAC)

Liang Liu, Jinfeng Xiang, Rufu Chen, Deliang Fu, Defei Hong, Jihui Hao, Yixiong Li, Jiangtao Li, Shengping Li, Yiping Mou, Gang Mai, Quanxing Ni, Li Peng, Renyi Qin, Honggang Qian, Chenghao Shao, Bei Sun, Yongwei Sun, Min Tao, Bole Tian, Hongxia Wang, Jian Wang, Liwei Wang, Wei Wang, Weilin Wang, Jun Zhang, Gang Zhao, Jun Zhou, Xianjun Yu

Pages: 900-907 Published online on: 30 December 2015
Open Access

Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition

Nikolaos Ioannou, Alan M. Seddon, Angus Dalgleish, David Mackintosh, Flavio Solca, Helmout Modjtahedi

Pages: 908-918 Published online on: 05 January 2016
Open Access

Importance of osteoprotegrin and receptor activator of nuclear factor κB in breast cancer response to hepatocyte growth factor and the bone microenvironment in vitro

Sioned Owen, Andrew J. Sanders, Malcolm D. Mason, Wen G. Jiang

Pages: 919-928 Published online on: 15 January 2016
Open Access

Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer

Huishan Zhao, Hefen Yu, Tracey A. Martin, Yuxiang Zhang, Gang Chen, Wen G. Jiang

Pages: 929-936 Published online on: 15 January 2016
Open Access

miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells

Nobuhiko Nishijima, Masahiro Seike, Chie Soeno, Mika Chiba, Akihiko Miyanaga, Rintaro Noro, Teppei Sugano, Masaru Matsumoto, Kaoru Kubota, Akihiko Gemma

Pages: 937-944 Published online on: 11 January 2016
Open Access

Identification of haptoglobin peptide as a novel serum biomarker for lung squamous cell carcinoma by serum proteome and peptidome profiling

Tetsuya Okano, Masahiro Seike, Hidehiko Kuribayashi, Chie Soeno, Takeo Ishii, Kozui Kida, Akihiko Gemma

Pages: 945-952 Published online on: 11 January 2016
Open Access

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy

Romana Mikyšková, Ivan Štěpánek, Marie Indrová, Jana Bieblová, Jana Šímová, Iva Truxová, Irena Moserová, Jitka Fučíková, Jiřina Bartůňková, Radek Špíšek, Milan Reiniš

Pages: 953-964 Published online on: 29 December 2015
Open Access

MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma

Kangsheng Tu, Zhikui Liu, Bowen Yao, Shaoshan Han, Wei Yang

Pages: 965-974 Published online on: 28 December 2015
Open Access

Overexpression of the S100A2 protein as a prognostic marker for patients with stage II and III colorectal cancer

Taiki Masuda, Toshiaki Ishikawa, Kaoru Mogushi, Satoshi Okazaki, Megumi Ishiguro, Satoru Iida, Hiroshi Mizushima, Hiroshi Tanaka, Hiroyuki Uetake, Kenichi Sugihara

Pages: 975-982 Published online on: 11 January 2016
Open Access

PP2B and ERK1/2 regulate hyaluronan synthesis of HT168 and WM35 human melanoma cell lines

Éva Katona, Tamás Juhász, Csilla Szűcs Somogyi, Tibor Hajdú, Csaba Szász, Kálmán Rácz, Endre Kókai, Pál Gergely, Róza Zákány

Pages: 983-997 Published online on: 28 December 2015
Open Access

Insulin-like growth factor 2 mRNA-binding protein-3 as a marker for distinguishing between cutaneous squamous cell carcinoma and keratoacanthoma

Akiko Kanzaki, Mitsuhiro Kudo, Shin-Ichi Ansai, Wei-Xia Peng, Kousuke Ishino, Tetsushi Yamamoto, Ryuichi Wada, Takenori Fujii, Kiyoshi Teduka, Kiyoko Kawahara, Yoko Kawamoto, Taeko Kitamura, Seiji Kawana, Hidehisa Saeki, Zenya Naito

Pages: 1007-1015 Published online on: 05 January 2016
Open Access

Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells

Yi Fang, Qian Zhang, Xin Wang, Xue Yang, Xiangyu Wang, Zhen Huang, Yuchen Jiao, Jing Wang

Pages: 1016-1028 Published online on: 11 January 2016

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222

Eleonora Brognara, Enrica Fabbri, Giulia Montagner, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Nicoletta Bianchi, Alessia Finotti, Giulia Breveglieri, Monica Borgatti, Ilaria Lampronti, Roberta Milani, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari

Pages: 1029-1038 Published online on: 24 December 2015

The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells

Antonietta Notaro, Selenia Sabella, Ornella Pellerito, Renza Vento, Giuseppe Calvaruso, Michela Giuliano

Pages: 1039-1044 Published online on: 24 December 2015

ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma

Jayson Neil, Craig Shannon, Avinash Mohan, Dimitri Laurent, Raj Murali, Meena Jhanwar-Uniyal

Pages: 1045-1052 Published online on: 28 December 2015

Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma

Yu Jin Cho, Wonyoung Kang, Sung Heon Kim, Jason K. Sa, Nayoung Kim, Patrick J. Paddison, Misuk Kim, Kyeung Min Joo, Young-Il Hwang, Do-Hyun Nam

Pages: 1053-1062 Published online on: 11 January 2016

Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism

Yanchen Liu, Tianbiao Zou, Shuhuai Wang, Hong Chen, Dongju Su, Xiaona Fu, Qingyuan Zhang, Xinmei Kang

Pages: 1063-1072 Published online on: 19 January 2016

Quinalizarin enhances radiosensitivity of nasopharyngeal carcinoma cells partially by suppressing SHP-1 expression

Xiaofen Pan, Rui Meng, Zhonghua Yu, Jingjing Mou, Sha Liu, Ziyi Sun, Zhenwei Zou, Gang Wu, Gang Peng

Pages: 1073-1084 Published online on: 14 January 2016

Overexpression of SDF-1 activates the NF-κB pathway to induce epithelial to mesenchymal transition and cancer stem cell-like phenotypes of breast cancer cells

Lingxin Kong, Sufen Guo, Chunfeng Liu, Yiling Zhao, Chong Feng, Yunshuang Liu, Tao Wang, Caijuan Li

Pages: 1085-1094 Published online on: 15 January 2016

Tamoxifen enhances the differentiation-inducing and growth-inhibitory effects of all-trans retinoic acid in acute promyelocytic leukemia cells

Koji Adachi, Yoshio Honma, Takaaki Miyake, Koshi Kawakami, Tsutomu Takahashi, Junji Suzumiya

Pages: 1095-1102 Published online on: 19 January 2016

Estimation of copy number aberrations: Comparison of exome sequencing data with SNP microarrays identifies homozygous deletions of 19q13.2 and CIC in neuroblastoma

Susanne Fransson, Malin Östensson, Anna Djos, Niloufar Javanmardi, Per Kogner, Tommy Martinsson

Pages: 1103-1116 Published online on: 19 January 2016

Twist mediates an aggressive phenotype in human colorectal cancer cells

Jun-Jian Deng, Wei Zhang, Xi-Ming Xu, Fan Zhang, Wei-Ping Tao, Jun-Jie Ye, Wei Ge

Pages: 1117-1124 Published online on: 15 January 2016

AP-2α inhibits hepatocellular carcinoma cell growth and migration

Wenhuan Huang, Cheng Chen, Zhongheng Liang, Junlu Qiu, Xinxin Li, Xiang Hu, Shuanglin Xiang, Xiaofeng Ding, Jian Zhang

Pages: 1125-1134 Published online on: 05 January 2016

Tumor suppressive microRNA-138 inhibits metastatic potential via the targeting of focal adhesion kinase in Ewing's sarcoma cells

Kazuhiro Tanaka, Masanori Kawano, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura

Pages: 1135-1144 Published online on: 05 January 2016

Screening of mammalian DNA polymerase and topoisomerase inhibitors from Garcinia mangostana L. and analysis of human cancer cell proliferation and apoptosis

Takefumi Onodera, Yukiko Takenaka, Sachiko Kozaki, Takao Tanahashi, Yoshiyuki Mizushina

Pages: 1145-1154 Published online on: 05 January 2016

Downregulation of β3 integrin by miR-30a-5p modulates cell adhesion and invasion by interrupting Erk/Ets‑1 network in triple-negative breast cancer

Wentong Li, Chuanliang Liu, Chunling Zhao, Limin Zhai, Shijun Lv

Pages: 1155-1164 Published online on: 05 January 2016

Galectin-9: An anticancer molecule for gallbladder carcinoma

Tomoko Tadokoro, Asahiro Morishita, Shintaro Fujihara, Hisakazu Iwama, Toshiro Niki, Koji Fujita, Emiko Akashi, Shima Mimura, Kyoko Oura, Teppei Sakamoto, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Hirohito Yoneyama, Takashi Himoto, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 1165-1174 Published online on: 19 January 2016

WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells

Liang Xu, Le Zhang, Chun Hu, Shujing Liang, Xiaochun Fei, Ningning Yan, Yanyun Zhang, Fengchun Zhang

Pages: 1175-1186 Published online on: 13 January 2016

Cytotoxic mechanism of PLK1 inhibitor GSK461364 against osteosarcoma: Mitotic arrest, apoptosis, cellular senescence, and synergistic effect with paclitaxel

Yi-Sheng Chou, Chueh-Chuan Yen, Wei-Ming Chen, Yung-Chan Lin, Yao-Shan Wen, Wei-Ting Ke, Jir-You Wang, Chun-Yu Liu, Muh-Hwa Yang, Tain-Hsiung Chen, Chien-Lin Liu

Pages: 1187-1194 Published online on: 20 January 2016

A double-negative feedback loop between EZH2 and miR-26a regulates tumor cell growth in hepatocellular carcinoma

Chunbo Zhuang, Pei Wang, Da Huang, Luming Xu, Xiaobei Wang, Lin Wang, Lihua Hu

Pages: 1195-1204 Published online on: 13 January 2016

Transformation of primary human hepatocytes in hepatocellular carcinoma

Mauro Montalbano, Cristiana Rastellini, Xiaofu Wang, Tiziana Corsello, Mahmoud A. Eltorky, Renza Vento, Luca Cicalese

Pages: 1205-1217 Published online on: 28 December 2015

The antitumor efficacy of a novel adenovirus-mediated anti-p21Ras single chain fragment variable antibody on human cancers in vitro and in vivo

Ju-Lun Yang, Xin-Yan Pan, Wen-Xing Zhao, Qi-Chan Hu, Feng Ding, Qiang Feng, Gui-Yun Li, Ying Luo

Pages: 1218-1228 Published online on: 13 January 2016

Bufalin enhances anti-angiogenic effect of sorafenib via AKT/VEGF signaling

Haiyong Wang, Chenyue Zhang, Zhouyu Ning, Litao Xu, Xiaoyan Zhu, Zhiqiang Meng

Pages: 1229-1241 Published online on: 05 January 2016
Open Access

Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21)

Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Ingvild Lobmaier, Sverre Heim

Pages: 1242-1250 Published online on: 28 December 2015

RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells

Toyonobu Maeda, Satoshi Yuzawa, Atsuko Suzuki, Yuh Baba, Yukio Nishimura, Yasumasa Kato

Pages: 1251-1257 Published online on: 05 January 2016

Surface vacuolar ATPase in ameloblastoma contributes to tumor invasion of the jaw bone

Shohei Yoshimoto, Hiromitsu Morita, Ryota Matsubara, Takeshi Mitsuyasu, Yuko Imai, Shunichi Kajioka, Masahiro Yoneda, Yushi Ito, Takao Hirofuji, Seiji Nakamura, Masato Hirata

Pages: 1258-1270 Published online on: 19 January 2016

1,25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-κB pathway

Zhiquan Huang, Yeqing Liu, Zixian Huang, Haifeng Li, Xiangfeng Gan, Zhuojian Shen

Pages: 1271-1279 Published online on: 15 January 2016

Optimizing treatment of hepatic metastases from colorectal cancer: Resection or resection plus ablation?

Antonio Chiappa, Emilio Bertani, Andrew P. Zbar, Diego Foschi, Nicola Fazio, Maria Zampino, Claudio Belluco, Franco Orsi, Paolo Della Vigna, Guido Bonomo, Marco Venturino, Carlo Ferrari, Roberto Biffi

Pages: 1280-1289 Published online on: 05 January 2016

KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma

Sian Cregan, Lauran McDonagh, Yun Gao, Martin P. Barr, Kenneth J. O'Byrne, Stephen P. Finn, Sinead Cuffe, Steven G. Gray

Pages: 1290-1296 Published online on: 13 January 2016

Phosphorylated retinoblastoma protein is a potential predictive marker of irinotecan efficacy for colorectal cancer

Atsushi Ikai, Motoki Watanabe, Yoshihiro Sowa, Mitsuo Kishimoto, Akio Yanagisawa, Hitoshi Fujiwara, Eigo Otsuji, Toshiyuki Sakai

Pages: 1297-1304 Published online on: 12 January 2016

[Corrigendum] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells

Yasuyuki Izutani, Shingo Yogosawa, Yoshihiro Sowa, Toshiyuki Sakai

Pages: 1305-1305 Published online on: 30 December 2015

[Corrigendum] Upregulated LMO1 in prostate cancer acts as a novel coactivator of the androgen receptor

Hui Gu, Tong Liu, Xinze Cai, Yuxin Tong, Yan Li, Chunyu Wang, Feng Li

Pages: 1306-1306 Published online on: 18 January 2016
Journal Cover

Cover Legend PDF

March 2016
Volume 48 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2014 Impact Factor: 3.025
Ranked #30/211 Oncology
(total number of cites)

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