Journal Articles

Update on Epstein-Barr virus and gastric cancer (Review)

Aya Shinozaki-Ushiku, Akiko Kunita, Masashi Fukayama

Pages: 1421-1434 Published online on: 28 January 2015

Molecular basis of carcinogenesis in diabetic patients (Review)

Artur Matyszewski, Anna M. Czarnecka, Wojciech Solarek, Piotr Korzeń, Ilan J. Safir, Wojciech Kukwa, Cezary Szczylik

Pages: 1435-1443 Published online on: 03 February 2015

YAP/TAZ for cancer therapy: Opportunities and challenges (Review)

Liwen Guo, Lisong Teng

Pages: 1444-1452 Published online on: 05 February 2015
Open Access

γ‑tocotrienol prevents 5‑FU‑induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5‑FU‑induced activation of Nrf2

Hideyuki Takano, Yukihiro Momota, Kouichi Kani, Keiko Aota, Yoshiko Yamamura, Tomoko Yamanoi, Masayuki Azuma

Pages: 1453-1460 Published online on: 26 January 2015
Open Access

Slug contributes to cancer progression by direct regulation of ERα signaling pathway

Youqiang Li, Yanyuan Wu, Thomas C. Abbatiello, Warren L. Wu, Ju Ri Kim, Marianna Sarkissyan, Suren Sarkissyan, Seyung S. Chung, Yahya Elshimali, Jaydutt V. Vadgama

Pages: 1461-1472 Published online on: 05 February 2015
Open Access

A novel point-of-care system for high-speed real-time polymerase chain reaction testing for epidermal growth factor receptor mutations in bronchial lavage fluids after transbronchial biopsy in patients with non-small cell lung cancer

Tomohiro Sakamoto, Masahiro Kodani, Miyako Takata, Hiroki Chikumi, Masaki Nakamoto, Shizuka Nishii-Ito, Yasuto Ueda, Hiroki Izumi, Haruhiko Makino, Hirokazu Touge, Kenichi Takeda, Akira Yamasaki, Masaaki Yanai, Natsumi Tanaka, Tadashi Igishi, Eiji Shimizu

Pages: 1473-1480 Published online on: 04 February 2015
Open Access

New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane

Stine Hole, Astrid M. Pedersen, Susanne K. Hansen, Johan Lundqvist, Christina W. Yde, Anne E. Lykkesfeldt

Pages: 1481-1490 Published online on: 26 January 2015
Open Access

Gallic acid exerts a protective or an anti-proliferative effect on glioma T98G cells via dose-dependent epigenetic regulation mediated by miRNAs

Alessandro Paolini, Valeria Curti, Francesca Pasi, Giuliano Mazzini, Rosanna Nano, Enrica Capelli

Pages: 1491-1497 Published online on: 02 February 2015
Open Access

Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Kiyoko Umene, Megumi Yanokura, Kouji Banno, Haruko Irie, Masataka Adachi, Miho Iida, Kanako Nakamura, Yuya Nogami, Kenta Masuda, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki

Pages: 1498-1506 Published online on: 22 January 2015
Open Access

(-)-Epigallocatechingallate induces apoptosis in B lymphoma cells via caspase-dependent pathway and Bcl-2 family protein modulation

Jiangyan Wang, Yu'an Xie, Yan Feng, Litu Zhang, Xinping Huang, Xiaoyun Shen, Xiaoling Luo

Pages: 1507-1515 Published online on: 03 February 2015
Open Access

Antimicrobial peptide FF/CAP18 induces apoptotic cell death in HCT116 colon cancer cells via changes in the metabolic profile

Kengo Kuroda, Tomokazu Fukuda, Hiroshi Isogai, Kazuhiko Okumura, Marija Krstic-Demonacos, Emiko Isogai

Pages: 1516-1526 Published online on: 10 February 2015

Significance of SALL4 as a drug‑resistant factor in lung cancer

Nozomi Yanagihara, Daisuke Kobayashi, Kageaki Kuribayashi, Maki Tanaka, Tadashi Hasegawa, Naoki Watanabe

Pages: 1527-1534 Published online on: 03 February 2015

Long‑term exposure to leptin enhances the growth of prostate cancer cells

Terutaka Noda, Tadahiko Kikugawa, Nozomu Tanji, Noriyoshi Miura, Seiji Asai, Shigeki Higashiyama, Masayoshi Yokoyama

Pages: 1535-1542 Published online on: 23 January 2015

Tumor-suppressive microRNA-let-7a inhibits cell proliferation via targeting of E2F2 in osteosarcoma cells

Tatsuya Iwasaki, Kazuhiro Tanaka, Masanori Kawano, Ichiro Itonaga, Hiroshi Tsumura

Pages: 1543-1550 Published online on: 03 February 2015

The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells

Jin Ying, Masahiko Tsujii, Jumpei Kondo, Yoshito Hayashi, Motohiko Kato, Tomofumi Akasaka, Takuta Inoue, Eri Shiraishi, Tahahiro Inoue, Satoshi Hiyama, Yoshiki Tsujii, Akira Maekawa, Shoichiro Kawai, Tetsuji Fujinaga, Maekawa Araki, Shinichiro Shinzaki, Kenji Watabe, Tsutomu Nishida, Hideki Iijima, Tetsuo Takehara

Pages: 1551-1559 Published online on: 26 January 2015

CH5137291, an androgen receptor nuclear translocation-inhibiting compound, inhibits the growth of castration-resistant prostate cancer cells

Nobuyuki Ishikura, Hiromitsu Kawata, Ayako Nishimoto, Ryo Nakamura, Toshiaki Tsunenari, Miho Watanabe, Kazutaka Tachibana, Takuya Shiraishi, Hitoshi Yoshino, Akie Honma, Takashi Emura, Masateru Ohta, Toshito Nakagawa, Takao Houjo, Eva Corey, Robert L. Vessella, Yuko Aoki, Haruhiko Sato

Pages: 1560-1572 Published online on: 30 January 2015

Cystatin B as a potential diagnostic biomarker in ovarian clear cell carcinoma

Akane Takaya, Wei‑Xia Peng, Kousuke Ishino, Mitsuhiro Kudo, Tetsushi  Yamamoto, Ryuichi Wada, Toshiyuki Takeshita, Zenya Naito

Pages: 1573-1581 Published online on: 28 January 2015

Colon cancer stem cell markers CD44 and CD133 in patients with colorectal cancer and synchronous hepatic metastases

Feifeng Jing, Hun Jin Kim, Chang Hyun Kim, Young Jin Kim, Jae Hyuk Lee, Hyeong Rok Kim

Pages: 1582-1588 Published online on: 23 January 2015

Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes

Shanshan Zhang, Lei Han, Jianwei Wei, Zhendong Shi, Peiyu Pu, Jianning Zhang, Xubo Yuan, Chunsheng Kang

Pages: 1589-1600 Published online on: 22 January 2015

miR‑27a suppresses the clonogenic growth and migration of human glioblastoma multiforme cells by targeting BTG2

Wei-Qing Li, Hong-Yu Yu, Nan-Zhe Zhong, Li-Jun Hou, Yi-Ming Li, Jin He, Hui-Min Liu, Chun-Yan Xia, Yi-Cheng Lu

Pages: 1601-1608 Published online on: 22 January 2015

Activation of PKC‑δ in HTLV‑1‑infected T cells

Naoki Mori, Chie Ishikawa, Masachika Senba

Pages: 1609-1618 Published online on: 26 January 2015

The anthraquinone derivative Emodin inhibits angiogenesis and metastasis through downregulating Runx2 activity in breast cancer

Junchao Ma, Hong Lu, Shan Wang, Bin Chen, Zhaojie Liu, Xiaoqin Ke, Ting Liu, Jianjiang Fu

Pages: 1619-1628 Published online on: 10 February 2015

Pro‑apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells

Kamran Harati, Pawel Slodnik, Ansgar Michael Chromik, Björn Behr, Ole Goertz, Tobias Hirsch, Nicolai Kapalschinski, Ludger Klein‑Hitpass, Jonas Kolbenschlag, Waldemar Uhl, Marcus Lehnhardt, Adrien Daigeler

Pages: 1629-1636 Published online on: 27 January 2015

Prevalence of chromosomal rearrangements involving non-ETS genes in prostate cancer

Martina Kluth, Rami Galal, Antje Krohn, Joachim Weischenfeldt, Christina Tsourlakis, Lisa Paustian, Ramin Ahrary, Malik Ahmed, Sekander Scherzai, Anne Meyer, Hüseyin Sirma, Jan Korbel, Guido Sauter, Thorsten Schlomm, Ronald Simon, Sarah Minner

Pages: 1637-1642 Published online on: 27 January 2015

β-catenin knockdown inhibits pituitary adenoma cell proliferation and invasion via interfering with AKT and gelatinases expression

Chengcheng Zhao, Meng Zhang, Wenlan Liu, Chuanfang Wang, Qiusheng Zhang, Weiping Li

Pages: 1643-1650 Published online on: 02 February 2015

GDC-0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang

Pages: 1651-1658 Published online on: 04 February 2015

Naphthazarin enhances ionizing radiation-induced cell cycle arrest and apoptosis in human breast cancer cells

Min Young Kim, Seong-Joon Park, Jae Woong Shim, Kwangmo Yang, Ho Sung Kang, Kyu Heo

Pages: 1659-1666 Published online on: 28 January 2015

Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression

Xiu Shan, Faisal Aziz, Li Li Tian, Xiao Qi Wang, Qiu Yan, Ji Wei Liu

Pages: 1667-1676 Published online on: 10 February 2015

Fra‑1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro

Songshu Xiao, Yanhong Zhou, Wei Yi, Guijuan Luo, Bin Jiang, Qi Tian, Yueran Li, Min Xue

Pages: 1677-1684 Published online on: 04 February 2015

Bleb formation is induced by alkaline but not acidic pH in estrogen receptor silenced breast cancer cells

Maitham A. Khajah, Princy M. Mathew, Nada S. Alam-Eldin, Yunus A. Luqmani

Pages: 1685-1698 Published online on: 09 February 2015

Immune responses in patients with esophageal cancer treated with SART1 peptide‑pulsed dendritic cell vaccine

Miwako Narita, Tatsuo Kanda, Takashi Abe, Takayoshi Uchiyama, Minami Iwafuchi, Zhiyin Zheng, Aichun Liu, Tsutomu Kaifu, Shinichi Kosugi, Masahiro Minagawa, Kyogo Itoh, Masuhiro Takahashi

Pages: 1699-1709 Published online on: 23 January 2015

RIG-I suppresses the migration and invasion of hepatocellular carcinoma cells by regulating MMP9

Zhikui Liu, Changwei Dou, Yuli Jia, Qing Li, Xin Zheng, Yingmin Yao, Qingguang Liu, Tao Song

Pages: 1710-1720 Published online on: 26 January 2015

EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line

Yukio Nishimura, Soichi Takiguchi, Shigeru Ito, Kazuyuki Itoh

Pages: 1721-1729 Published online on: 04 February 2015

Ellagic acid induces cell cycle arrest and apoptosis through TGF-β/Smad3 signaling pathway in human breast cancer MCF-7 cells

Hong-Sheng Chen, Ming-Han Bai, Tao Zhang, Guo-Dong Li, Ming Liu

Pages: 1730-1738 Published online on: 03 February 2015

Resveratrol inhibits glioma cell growth via targeting oncogenic microRNAs and multiple signaling pathways

Guangxiu Wang, Fang Dai, Kai Yu, Zhifan Jia, Anling Zhang, Qiang Huang, Chunsheng Kang, Hao Jiang, Peiyu Pu

Pages: 1739-1747 Published online on: 02 February 2015

iTRAQ-based quantitative proteomic analysis of cervical cancer

Yibing Ding, Min Yang, Sha She, Haiyan Min, Xiaoming Xv, Xiaoping Ran, Yongzheng Wu, Wei Wang, Lei Wang, Long Yi, Yixuan Yang, Qian Gao

Pages: 1748-1758 Published online on: 29 January 2015

Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin-like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang

Pages: 1759-1767 Published online on: 26 January 2015

Dlx-2 is implicated in TGF-β- and Wnt-induced epithelial-mesenchymal, glycolytic switch, and mitochondrial repression by Snail activation

Su Yeon Lee, Hyun Min Jeon, Min Kyung Ju, Eui Kyong Jeong, Cho Hee Kim, Mi-Ae Yoo, Hye Gyeong Park, Song Iy Han, Ho Sung Kang

Pages: 1768-1780 Published online on: 04 February 2015

A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells

Yukari Nishii, Miki Yamaguchi, Yasutoshi Kimura, Tadashi Hasegawa, Hiroyuki Aburatani, Hiroaki Uchida, Koichi Hirata, Yuji Sakuma

Pages: 1781-1787 Published online on: 05 February 2015

Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer

Mei-Ying Liao, Mark Yen-Ping Kuo, Tung-Ying Lu, Yi-Ping Wang, Han-Chung Wu

Pages: 1788-1800 Published online on: 05 February 2015

Synergistic combination therapy with cotylenin A and vincristine in multiple myeloma models

Tsutomu Takahashi, Yoshio Honma, Takaaki Miyake, Koji Adachi, Saki Takami, Masahiro Okada, Satoshi Kumanomidou, Fumiyoshi Ikejiri, Yumi Jo, Chie Onishi, Koshi Kawakami, Ichiro Moriyama, Masaya Inoue, Junko Tanaka, Junji Suzumiya

Pages: 1801-1809 Published online on: 09 February 2015

Molecular response of 4T1-induced mouse mammary tumours and healthy tissues to zinc treatment

Marketa Sztalmachova, Jaromir Gumulec, Martina Raudenska, Hana Polanska, Monika Holubova, Jan Balvan, Kristyna Hudcova, Lucia Knopfova, Rene Kizek, Vojtech Adam, Petr Babula, Michal Masarik

Pages: 1810-1818 Published online on: 09 February 2015

Trends and variations in breast and colorectal cancer incidence from 1995 to 2011: A comparative study between Texas Cancer Registry and National Cancer Institute's Surveillance, Epidemiology and End Results data

Zheyu Liu, Yefei Zhang, Luisa Franzin, Janice N. Cormier, Wenyaw Chan, Hua Xu, Xianglin L. Du

Pages: 1819-1826 Published online on: 06 February 2015

Evaluation of ibuprofen loaded solid lipid nanoparticles and its combination regimens for pancreatic cancer chemoprevention

Arvind Thakkar, Sushma Chenreddy, Jeffrey Wang, Sunil Prabhu

Pages: 1827-1834 Published online on: 05 February 2015

Chrysin inhibits cell invasion by inhibition of Recepteur d'origine Nantais via suppressing early growth response-1 and NF-κB transcription factor activities in gastric cancer cells

Yong Xia, Sen Lian, Pham Ngoc Khoi, Hyun Joong Yoon, Jae Young Han, Kee Oh Chay, Kyung Keun Kim, Young Do Jung

Pages: 1835-1843 Published online on: 23 January 2015

Critical contribution of MCL-1 in EMT-associated chemo-resistance in A549 non-small cell lung cancer

Masayoshi Toge, Satoru Yokoyama, Shinichiro Kato, Hiroaki Sakurai, Kazutaka Senda, Yoshinori Doki, Yoshihiro Hayakawa, Naoki Yoshimura, Ikuo Saiki

Pages: 1844-1848 Published online on: 30 January 2015

Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells

Ranganatha R. Somasagara, Gagan Deep, Sangeeta Shrotriya, Manisha Patel, Chapla Agarwal, Rajesh Agarwal

Pages: 1849-1857 Published online on: 09 February 2015

[Corrigendum] Human β-defensin-3 inhibits migration of colon cancer cells via downregulation of metastasis-associated 1 family, member 2 expression

Satoko Uraki, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Yuji Inagaki, Suguru Ogura, Chika Kasai, Keiichiro Nojiri, Misao Yoneda, Norihiko Yamamoto, Yoshiyuki Takei, Tsutomu Nobori, Masaaki Ito

Pages: 1858-1858 Published online on: 03 February 2015
Journal Cover

Cover Legend PDF

April 2015
Volume 46 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2013 Impact Factor: 2.773
Ranked #30/202 Oncology
(total number of cites)

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