IMMUNOSUPPRESSION IN RENAL-TRANSPLANTATION DOES NOT INCREASE THE INCIDENCE OF NATIVE RENAL-CANCER

  • Authors: ST PIERCE, MA DOUKAS, T WAID
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  • Published online on: Tuesday, June 1, 1993
  • Pages: 1059-1062
  • DOI: 10.3892/ijo.2.6.1059

Abstract

A patient presented with metastatic renal cell cancer arising in a native kidney nine years after undergoing cadaveric renal transplantation. Ten other cases have been detailed in the literature over the past 15 years. The risk of renal cancer in hemodialysis patients increases with the duration of dialysis and acquisition of cystic disease. The incidence of renal cell cancers in renal transplant patients and dialysis patients is equivalent. In both groups of patients the carcinomas arise from acquired cysts, but unlike hemodialysis patients, the duration of prior hemodialysis in the transplant group does not appear to correlate with the risk of renal cell carcinoma. Immunosuppression to prevent graft rejection is associated with a dramatic increase in some cancers, but does not appear to be a factor in native renal cancer development. Ultrasound followed by arteriography to diagnose tumors in the subset of patients with cysts could be used for screening of the risk population. The cost of screening though may be prohibitive in diagnosing this rare complication in renal transplant patients.
Journal Cover

June 1993
Volume 2 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

2013 Impact Factor: 2.773
Ranked #30/202 Oncology
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APA
PIERCE, S., DOUKAS, M., & WAID, T. (1993). IMMUNOSUPPRESSION IN RENAL-TRANSPLANTATION DOES NOT INCREASE THE INCIDENCE OF NATIVE RENAL-CANCER. International Journal of Oncology, 2(6), 1059-1062.
MLA
PIERCE, DOUKAS, and T WAID. "IMMUNOSUPPRESSION IN RENAL-TRANSPLANTATION DOES NOT INCREASE THE INCIDENCE OF NATIVE RENAL-CANCER." International Journal of Oncology International Journal of Oncology 2.6 (1993): 1059-1062.
Chicago
PIERCE, DOUKAS, and T WAID. "IMMUNOSUPPRESSION IN RENAL-TRANSPLANTATION DOES NOT INCREASE THE INCIDENCE OF NATIVE RENAL-CANCER." International Journal of Oncology International Journal of Oncology 2 no. 6 (1993): 1059-1062.