Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)

  • Authors:
    • Sudhir Gupta
  • View Affiliations

  • Published online on: Wednesday, January 1, 2003
  • Pages: 15-20
  • DOI: 10.3892/ijo.22.1.15

Abstract

In recent years major progress has been made in understanding the molecular steps of death receptor and mitochondrial pathway of apoptosis. Mechanisms of NF-κB-mediated survival (anti-apoptotic) signal have been delineated. A novel anti-apoptotic mechanism of FLIP in the recruitment of RIP and TRAF-1 and TRAF-2 to activate ERK and NF-κB has been defined. These are some of the recent discoveries in death receptor and mitochondrial pathways of apoptosis that have been reviewed in this article.
Journal Cover

January 2003
Volume 22 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

2013 Impact Factor: 2.773
Ranked #30/202 Oncology
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APA
& Gupta, S. (2003). Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review). International Journal of Oncology, 22(1), 15-20.
MLA
and Sudhir Gupta. "Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)." International Journal of Oncology International Journal of Oncology 22.1 (2003): 15-20.
Chicago
and Sudhir Gupta. "Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)." International Journal of Oncology International Journal of Oncology 22 no. 1 (2003): 15-20.