Open Access

Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)

  • Authors:
    • Sheng Huang
    • Weiliang Zhao
    • Zihua Wang
    • Kai Tao
    • Xiaoyan Liu
    • Peng Chang
  • View Affiliations

  • Published online on: December 14, 2015     https://doi.org/10.3892/mmr.2015.4682
  • Pages: 1063-1069
  • Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cell-assisted lipotransfer (CAL) has been widely used in various clinical applications, including breast augmentation following mammectomy, soft‑tissue reconstruction and wound healing. However, the clinical application of CAL has been restricted due to the transplanted fat tissues being readily liquefied and absorbed. The present review examines 57 previously published studies involving CAL, including fat grafting or fat transfer with human adipose‑stem cells in all known databases. Of these 57 articles, seven reported the clinical application of CAL. In the 57 studies, the majority of the fat tissues were obtained from the abdomen via liposuction of the seven clinical studies, four were performed in patients requiring breast augmentation, one in a patient requiring facial augmentation, one in a patient requiring soft tissue augmentation/reconstruction and one in a patient requiring fat in their upper arms. Despite the potential risks, there has been an increased demand for CAL in in cosmetic or aesthetic applications. Thus, criteria and guidelines are necessary for the clinical application of CAL technology.
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February-2016
Volume 13 Issue 2

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Huang S, Zhao W, Wang Z, Tao K, Liu X and Chang P: Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review). Mol Med Rep 13: 1063-1069, 2016
APA
Huang, S., Zhao, W., Wang, Z., Tao, K., Liu, X., & Chang, P. (2016). Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review). Molecular Medicine Reports, 13, 1063-1069. https://doi.org/10.3892/mmr.2015.4682
MLA
Huang, S., Zhao, W., Wang, Z., Tao, K., Liu, X., Chang, P."Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)". Molecular Medicine Reports 13.2 (2016): 1063-1069.
Chicago
Huang, S., Zhao, W., Wang, Z., Tao, K., Liu, X., Chang, P."Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)". Molecular Medicine Reports 13, no. 2 (2016): 1063-1069. https://doi.org/10.3892/mmr.2015.4682