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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-August 2008 Volume 1 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Breast cancer: Molecular basis and therapeutic strategies (Review)

Giovanni Ligresti, Massimo Libra, Loredana Militello, Silvia Clementi, Marco Donia, Rosa Imbesi, Grazia Malaponte, Alessandro Cappellani, James A. McCubrey, Franca Stivala
Pages: 451-458
Published online on: 01 July 2008

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Article

Anticancer drug cis-4-hydroxy-L-proline: Correlation of preclinical toxicology with clinical parameters of liver function

Heather Dickens, Anett Ullrich, Dieter Runge, Berno Mueller, Ulrike Olszewski, Gerhard Hamilton
Pages: 459-464
Published online on: 01 July 2008

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Article

Zebularine-induced reduction in VEGF secretion by HIF-1α degradation in oral squamous cell carcinoma

Maiko Suzuki, Fumiaki Shinohara, Hidemi Rikiishi
Pages: 465-471
Published online on: 01 July 2008

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Article

Immunohistochemical expression of p63 in esophageal Barrett's adenocarcinoma

Tadashi Hara, Hiroshi Kijima, Soichiro Yamamoto, Yosifumi Kise, Tomoko Hanashi, Takayuki Nishi, Osamu Chino, Hideo Shimada, Makiko Tanaka, Sadaki Inokuchi, Hiroyasu Makuuchi
Pages: 473-477
Published online on: 01 July 2008

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Article

Gene silencing of hPRLR mRNA by RNA interference in human breast cancer cells

Qinjun Wei, Yajie Lu, Mei Pan, Yongquian Shu, Xin Cao
Pages: 479-483
Published online on: 01 July 2008

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Article

γδ T cells as potential contributors to the progression of parapsoriasis to mycosis fungoides

Matteo Bordignon, Anna Belloni Fortina, Barbara Pigozzi, Mauro Alaibac
Pages: 485-488
Published online on: 01 July 2008

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Article

The effect of neutrophil elastase inhibitor on acute tubular necrosis after renal ischemia-reperfusion injury

Masahide Matsuyama, Takuma Hayama, Kiyoaki Funao, Toshihide Naganuma, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani, Rikio Yoshimura
Pages: 489-492
Published online on: 01 July 2008

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Article

The role of arachidonic acid in a rat renal ischemia-reperfusion injury model

Masahide Matsuyama, Rikio Yoshimura, Kiyoaki Funao, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani
Pages: 493-497
Published online on: 01 July 2008

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Article

Relationship between peroxisome proliferator-activated receptor-γ and renal ischemia-reperfusion injury

Masahide Matsuyama, Rikio Yoshimura, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Tatsuya Nakatani
Pages: 499-503
Published online on: 01 July 2008

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Article

Increased expression of epidermal growth factor receptor and betacellulin during the early stage of gastric ulcer healing

Geun Hae Choi, Ho Sung Park, Kyung Ryoul Kim, Ha Na Choi, Kyu Yun Jang, Myoung Ja Chung, Myoung Jae Kang, Dong Geun Lee, Woo Sung Moon
Pages: 505-510
Published online on: 01 July 2008

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Article

Epigallocatechin-3-gallate exhibits anti-tumor effect by perturbing redox homeostasis, modulating the release of pro-inflammatory mediators and decreasing the invasiveness of glioblastoma cells

Anindita Agarwal, Vivek Sharma, Richa Tewari, Nitin Koul, Christy Joseph, Ellora Sen
Pages: 511-515
Published online on: 01 July 2008

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Article

Polymorphisms of the matrix metalloproteinases associated with prostate cancer

Sabrina Thalita Dos Reis, Fabiola Elizabeth Villanova, Priscila Maria De Andrade, José Pontes, Iran Amorim Silva, Flávio Canelas Canavez, Adriana Sañudo, Miguel Srougi, Kátia Ramos Moreira Leite
Pages: 517-520
Published online on: 01 July 2008

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Article

Transarterial chemoembolization as salvage therapy after unsuccessful hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma

Kazuta Fukumori, Yoichi Yano, Eiji Ando, Shuji Sumie, Kotoro Kuwaki, Fumihiko Yamashita, Masatoshi Tanaka, Michio Sata
Pages: 521-524
Published online on: 01 July 2008

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Article

Significant association of XRCC4 single nucleotide polymorphisms with prostate cancer susceptibility in Taiwanese males

Chao-Hsiang Chang, Chang-Fang Chiu, Hsi-Chin Wu, Hsien-Chang Tseng, Chung-Hsing Wang, Cheng-Chieh Lin, Chia-Wen Tsai, Shiu-Yun Liang, Cheng-Li Wang, Da-Tian Bau
Pages: 525-530
Published online on: 01 July 2008

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Article

Direct evidence that heterogeneity necessitates and limits the use of multidrug chemotherapy in colon cancer

Yasuhiro Inoue, Yuji Toiyama, Tuyoshi Yokoe, Koji Tanaka, Chikao Miki, Masato Kusunoki
Pages: 531-535
Published online on: 01 July 2008

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Article

Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro

Suguru Fukahori, Hirohisa Yano, Jun Akiba, Sachiko Ogasawara, Seiya Momosaki, Sakiko Sanada, Keitaro Kuratomi, Yasuhiro Ishizaki, Fukuko Moriya, Minoru Yagi, Masamichi Kojiro
Pages: 537-542
Published online on: 01 July 2008

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Article

Neovascularization and oxidative stress in the progression of non-alcoholic steatohepatitis

Mitsuteru Kitade, Hitoshi Yoshiji, Hideyuki Kojima, Yasuhide Ikenaka, Ryuichi Noguchi, Kosuke Kaji, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Kei Moriya, Hideto Kawaratani, Takemi Akahane, Hiroshi Fukui
Pages: 543-548
Published online on: 01 July 2008

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Article

Risk analysis of colorectal cancer in women with endometrial carcinoma

Mara Fornasarig, Alessandro Marco Minisini, Silvia Clementi, Ettore Bidoli, Alessandra Viel, Renato Cannizzaro, Elio Campagnutta, Gianni Boz, Massimo Libra
Pages: 549-553
Published online on: 01 July 2008

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Article

Methylation status of the long control region of HPV 16 in clinical cervical specimens

Die Hong, Feng Ye, Weiguo Lu, Ying Hu, Xiaoyun Wan, Yaxia Chen, Xing Xie
Pages: 555-560
Published online on: 01 July 2008

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Article

A polymorphism in the 3'-utr of cyclooxygenase-2 and the risk of gastric cancer

Tomoyuki Shibata, Tomiyasu Arisawa, Tomomitsu Tahara, Ichiro Hirata, Hiroshi Nakano
Pages: 561-564
Published online on: 01 July 2008

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Article

Expression of cytokeratin 19 in the cytosolic fraction of thyroid lesions: ELISA and Western blot analysis

Anna Krzeslak, Zuzanna Gaj, Lech Pomorski, Anna Lipinska
Pages: 565-569
Published online on: 01 July 2008

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Article

SPARC-like1 mRNA is overexpressed in human uterine leiomyoma

Andre Luiz Mencalha, Alexandre Levinsphul, Louise Calil Deterling, Luciana Pizzatti, Eliana Abdelhay
Pages: 571-574
Published online on: 01 July 2008

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Article

2,2'-Dihydroxychalcone, a glutathione transferase inhibitor, sensitises human colon adenocarcinoma cells to chlorambucil and melphalan, but not to actinomycin D

Kenneth Goh, Yufan Chen, Lin Zheng, Laichun Ong, Yi Jin, Pierce Chow, Kai Zhang
Pages: 575-579
Published online on: 01 July 2008

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Article

Vitamin D3 inhibits expression of pemphigus vulgaris antigen desmoglein 3: Implication of a partial mechanism in the pharmacological effect of vitamin D3 on skin diseases

Chiaki Yamamoto, Katsuto Tamai, Hajime Nakano, Yasushi Matsuzaki, Takahide Kaneko, Daisuke Sawamura
Pages: 581-583
Published online on: 01 July 2008

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Article

Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia

Ferdinand Von Eggeling, Annett Bleul, Ivan F. Loncarevic, Susanne Michel, Anita Heller, Christian Melle
Pages: 585-587
Published online on: 01 July 2008

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Article

Detection of autoantibodies to multiple tumor-associated antigens in the immunodiagnosis of ovarian cancer

Liuxia Li, Kaijuan Wang, Liping Dai, Peng Wang, Xuan-Xian Peng, Jian-Ying Zhang
Pages: 589-594
Published online on: 01 July 2008

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Article

Modification of the effect of smoking on cholesterol in Japanese carriers of a PTPN11 polymorphism

Rieko Okada, Koji Suzuki, Kazuko Nishio, Yoshiko Ishida, Sayo Kawai, Yasuyuki Goto, Mariko Naito, Kenji Wakai, Yoshinori Ito, Nobuyuki Hamajima
Pages: 595-598
Published online on: 01 July 2008

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Article

Deregulated expression of the per2 gene in human colorectal carcinoma

Michal Zeman, Marián Vician, Jana Monosíková, Richard Reis, Iveta Herichová
Pages: 599-603
Published online on: 01 July 2008

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Editorial Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Review Open Access

Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Review Open Access

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Review Open Access

Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Review Open Access

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Review Open Access

Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Review Open Access

Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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Article Open Access

ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Review Open Access

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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Review Open Access

m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

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[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

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Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

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Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
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[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
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Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

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Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

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Article Number: 214
Published online on: 29 May 2026

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