1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
2
|
Edge SB and Compton CC: The American Joint
Committee on Cancer: The 7th edition of the AJCC cancer staging
manual and the future of TNM. Ann Surg Oncol. 17:1471–1474. 2010.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Siegel R, Ward E, Brawley O and Jemal A:
Cancer statistics, 2011: The impact of eliminating socioeconomic
and racial disparities on premature cancer deaths. CA Cancer J
Clin. 61:212–236. 2011. View Article : Google Scholar : PubMed/NCBI
|
4
|
Nagtegaal ID and Quirke P: Revised
staging: Is it really better, or do we not know? J Clin Oncol.
28:e397–e400. 2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Graziano F and Cascinu S: Prognostic
molecular markers for planning adjuvant chemotherapy trials in
Dukes' B colorectal cancer patients: How much evidence is enough?
Ann Oncol. 14:1026–1038. 2003. View Article : Google Scholar : PubMed/NCBI
|
6
|
Zhao M and Klionsky DJ: AMPK-dependent
phosphorylation of ULK1 induces autophagy. Cell Metab. 13:119–120.
2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Mizushima N, Levine B, Cuervo AM and
Klionsky DJ: Autophagy fights disease through cellular
self-digestion. Nature. 451:1069–1075. 2008. View Article : Google Scholar : PubMed/NCBI
|
8
|
Wong PM, Puente C, Ganley IG and Jiang X:
The ULK1 complex: Sensing nutrient signals for autophagy
activation. Autophagy. 9:124–137. 2013. View Article : Google Scholar : PubMed/NCBI
|
9
|
Kim J, Kundu M, Viollet B and Guan KL:
AMPK and mTOR regulate autophagy through direct phosphorylation of
Ulk1. Nat Cell Biol. 13:132–141. 2011. View
Article : Google Scholar : PubMed/NCBI
|
10
|
Lee JW, Park S, Takahashi Y and Wang HG:
The association of AMPK with ULK1 regulates autophagy. PLoS One.
5:e153942010. View Article : Google Scholar : PubMed/NCBI
|
11
|
Hosokawa N, Hara T, Kaizuka T, Kishi C,
Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, et
al: Nutrient-dependent mTORC1 association with the
ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell.
20:1981–1991. 2009. View Article : Google Scholar : PubMed/NCBI
|
12
|
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM,
Cao J, Kundu M and Kim DH: ULK-Atg13-FIP200 complexes mediate mTOR
signaling to the autophagy machinery. Mol Biol Cell. 20:1992–2003.
2009. View Article : Google Scholar : PubMed/NCBI
|
13
|
Jiang S, Li Y, Zhu YH, Wu XQ, Tang J, Li
Z, Feng GK, Deng R, Li DD, Luo RZ, et al: Intensive expression of
UNC-51-like kinase 1 is a novel biomarker of poor prognosis in
patients with esophageal squamous cell carcinoma. Cancer Sci.
102:1568–1575. 2011. View Article : Google Scholar : PubMed/NCBI
|
14
|
Tang J, Deng R, Luo RZ, Shen GP, Cai MY,
Du ZM, Jiang S, Yang MT, Fu JH and Zhu XF: Low expression of ULK1
is associated with operable breast cancer progression and is an
adverse prognostic marker of survival for patients. Breast Cancer
Res Treat. 134:549–560. 2012. View Article : Google Scholar : PubMed/NCBI
|
15
|
Cai MY, Hou JH, Rao HL, Luo RZ, Li M, Pei
XQ, Lin MC, Guan XY, Kung HF, Zeng YX and Xie D: High expression of
H3K27me3 in human hepatocellular carcinomas correlates closely with
vascular invasion and predicts worse prognosis in patients. Mol
Med. 17:12–20. 2011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Camp RL, Dolled-Filhart M and Rimm DL:
X-tile: A new bio-informatics tool for biomarker assessment and
outcome-based cut-point optimization. Clin Cancer Res.
10:7252–7259. 2004. View Article : Google Scholar : PubMed/NCBI
|
17
|
Raeside DE: Monte Carlo principles and
applications. Phys Med Biol. 21:181–197. 1976. View Article : Google Scholar : PubMed/NCBI
|
18
|
Brezden-Masley C and Polenz C: Current
practices and challenges of adjuvant chemotherapy in patients with
colorectal cancer. Surg Oncol Clin N Am. 23:49–58. 2014. View Article : Google Scholar : PubMed/NCBI
|
19
|
O'Connell JB, Maggard MA and Ko CY: Colon
cancer survival rates with the new American Joint Committee on
Cancer sixth edition staging. J Natl Cancer Inst. 96:1420–1425.
2004. View Article : Google Scholar : PubMed/NCBI
|
20
|
Oh HS, Chung HJ, Kim HK and Choi JS:
Differences in overall survival when colorectal cancer patients are
stratified into new TNM staging strategy. Cancer Res Treat.
39:61–64. 2007. View Article : Google Scholar : PubMed/NCBI
|
21
|
Kim KH, Yang SS, Yoon YS, Lim SB, Yu CS
and Kim JC: Validation of the seventh edition of the American Joint
Committee on Cancer tumor-node-metastasis (AJCC TNM) staging in
patients with stage II and stage III colorectal carcinoma: Analysis
of 2511 cases from a medical centre in Korea. Colorectal Dis.
13:e220–e226. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Ross JS: Biomarker-based selection of
therapy for colorectal cancer. Biomarkers Med. 5:319–332. 2011.
View Article : Google Scholar
|
23
|
Rizzo S, Bronte G, Fanale D, Corsini L,
Silvestris N, Santini D, Gulotta G, Bazan V, Gebbia N, Fulfaro F
and Russo A: Prognostic vs predictive molecular biomarkers in
colorectal cancer: Is KRAS and BRAF wild type status required for
anti-EGFR therapy? Cancer Treat Rev. 36:(Sul 3). S56–S61. 2010.
View Article : Google Scholar : PubMed/NCBI
|
24
|
Yokota T: Are KRAS/BRAF mutations potent
prognostic and/or predictive biomarkers in colorectal cancers?
Anticancer Agents Med Chem. 12:163–171. 2012. View Article : Google Scholar : PubMed/NCBI
|
25
|
Hönscheid P, Datta K and Muders MH:
Autophagy: Detection, regulation and its role in cancer and therapy
response. Int J Radiat Biol. 90:628–635. 2014. View Article : Google Scholar : PubMed/NCBI
|
26
|
Schmukler E, Kloog Y and Pinkas-Kramarski
R: Ras and autophagy in cancer development and therapy. Oncotarget.
5:577–586. 2014.PubMed/NCBI
|
27
|
Mizushima N: The role of the Atg1/ULK1
complex in autophagy regulation. Curr Opin Cell Biol. 22:132–139.
2010. View Article : Google Scholar : PubMed/NCBI
|
28
|
Mathonnet M, Perraud A, Christou N, Akil
H, Melin C, Battu S, Jauberteau MO and Denizot Y: Hallmarks in
colorectal cancer: Angiogenesis and cancer stem-like cells. World J
Gastroenterol. 20:4189–4196. 2014. View Article : Google Scholar : PubMed/NCBI
|