Colloid (mucinous non-cystic) carcinoma of the pancreas: A case report

Gao,Yang; Zhu,Ya‑Yun; Yuan,Zhou

doi:10.3892/ol.2015.3733

Colloid (mucinous non-cystic) carcinoma of the pancreas: A case report

Authors:
- Yang Gao
- Ya‑Yun Zhu
- Zhou Yuan
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Affiliations: Department of General Surgery, Shanghai Jiao Tong University Affiliated to Sixth People's Hospital, Shanghai 200233, P.R. China
Published online on: September 21, 2015 https://doi.org/10.3892/ol.2015.3733
Pages: 3195-3198

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Abstract

Colloid carcinoma (CC) of the pancreas, also known as mucinous non-cystic carcinoma, is a rare histological variant of pancreatic cancer. The present study reports the case of a 65‑year‑old male with a pancreatic head tumor 4.6x3.1 cm in size. The tumor had not invaded the superior mesenteric or celiac arteries. Laboratory data showed elevated alkaline phosphatase, γ‑gluytamyl transpeptidase and cancer antigen 19‑9 (CA19‑9) levels. The patient underwent a pancreaticoduodenectomy (PD), and the pathology revealed CC extending to the submucosa of the duodenum, with mild atypical hyperplasia of the pancreatic duct. The patient was negative for circulating tumor cells, indicating a good prognosis. The CA19‑9 concentration decreased to within the normal range following surgery. The present study reports a rare case of CC of the pancreas presenting with obstructive jaundice, in which a PD procedure was performed. Primary surgical treatment with curative intent is the optimal management and this subtype of pancreatic cancer is associated with a better prognosis compared with pancreatic ductal adenocarcinoma.

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