Biliary papillomatosis with malignant transformation: A case report and review of the literature

Gu,Chichang; Lin,Ye; Jin,Haosheng; Jian,Zhixiang

doi:10.3892/ol.2015.3682

Biliary papillomatosis with malignant transformation: A case report and review of the literature

Authors:
- Chichang Gu
- Ye Lin
- Haosheng Jin
- Zhixiang Jian
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Affiliations: Second Department of General Surgery, Shunde First People's Hospital Affiliated to Southern Medical University, Foshan, Guangdong 528300, P.R. China, Department of General Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guaugzhou, Guangdong 510080, P.R. China
Published online on: September 8, 2015 https://doi.org/10.3892/ol.2015.3682
Pages: 3315-3317

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Abstract

Biliary papillomatosis is a rare benign tumor that possesses a high potential for malignant transformation, and is frequently misdiagnosed. In the present report, a case of biliary papillomatosis with malignant transformation in a 63‑year‑old female, with a 19‑year history of cholelithiasis, is presented. The patient presented with right epigastric pain and magnetic resonance imaging revealed a diffuse mass in the right liver lobe, which extended through the common bile duct. Definitive preoperative diagnosis was unable to be established; however, following surgical resection of the tumor, a diagnosis of biliary papillomatosis with malignant transformation was confirmed by pathological examination. The patient was followed up seven months later and no recurrence was detected. A supplementary review of previously published literature is additionally presented.

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