Primary malignant non‑Hodgkin's lymphoma of the breast: A case report

Zhao,Yun‑Fei; Jiao,Feng; Liang,Hai‑Qiao; Luo,Qi‑Chi; Zhao,Lin‑Wei

doi:10.3892/ol.2014.2612

Primary malignant non‑Hodgkin's lymphoma of the breast: A case report

Authors:
- Yun‑Fei Zhao
- Feng Jiao
- Hai‑Qiao Liang
- Qi‑Chi Luo
- Lin‑Wei Zhao
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Affiliations: Department of Pathology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China, Department of Oncology, Shanghai Jiao Tong University Affiliated First People's Hospital, Shanghai 201620, P.R. China, Department of Radiology, Suining Central Hospital, Suining, Sichuan 629000, P.R. China
Published online on: October 10, 2014 https://doi.org/10.3892/ol.2014.2612
Pages: 2597-2600

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Abstract

Primary malignant lymphoma of the breast (PLB) is a rare disease. Treatment options include surgical resection, systemic chemotherapy, radiation and immunotherapy. At present, the optimum treatment combination remains controversial. The present study reports the case of a 39‑year‑old female with a six month history of a painless mass in the left breast. The mass was excised following medical examination. A diagnosis of diffuse large B‑cell lymphoma was determined as a result of histological and immunohistochemical profile analysis. Further examinations excluded metastatic disease. Thus, finally, PLB (diffuse large B‑cell lymphoma type) was diagnosed. The patient was treated with adjuvant systemic chemotherapy and consolidated radiation and a positive response was observed. During the 10 months of follow‑up, no evidence of disease recurrence was identified. At present, the patient is scheduled for regular follow‑up appointments. As the prevalence of PLB is increasing, the details of this rare case may aid clinicians treating similar patients, and highlight the importance of this disease.

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