Ki67 as a predictor of poor prognosis in patients with triple‑negative breast cancer

  • Authors:
    • Haitao Li
    • Xinghua Han
    • Yingxin Liu
    • Guodong Liu
    • Guomin Dong
  • View Affiliations

  • Published online on: October 15, 2014     https://doi.org/10.3892/ol.2014.2618
  • Pages: 149-152
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The aim of the current study was to investigate the expression of the proliferation antigen, Ki67, in triple‑negative breast cancer (TNBC) and its correlation with clinicopathological factors. The expression of Ki67 and other biological indicators in 24 cases of TNBC tissues and 178 cases of non‑TNBC tissues were detected using immunohistochemistry. Their correlation with the clinicopathological factors were also analyzed using the  χ2 test. The positive rate of Ki67 expression in TNBC tissues was 83.3%, exhibiting a statistically significant difference when compared with that in non‑TNBC tissues (73.0%) (P<0.05). The expression of Ki67 in breast cancer tissue significantly correlated with the tumor size and lymph node metastases; however, no correlation was observed with the age and the clinical stage. Ki67 may be an indicator of poor prognosis in TNBC patients.
View Figures
View References

Related Articles

Journal Cover

January-2015
Volume 9 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Li H, Han X, Liu Y, Liu G and Dong G: Ki67 as a predictor of poor prognosis in patients with triple‑negative breast cancer. Oncol Lett 9: 149-152, 2015
APA
Li, H., Han, X., Liu, Y., Liu, G., & Dong, G. (2015). Ki67 as a predictor of poor prognosis in patients with triple‑negative breast cancer. Oncology Letters, 9, 149-152. https://doi.org/10.3892/ol.2014.2618
MLA
Li, H., Han, X., Liu, Y., Liu, G., Dong, G."Ki67 as a predictor of poor prognosis in patients with triple‑negative breast cancer". Oncology Letters 9.1 (2015): 149-152.
Chicago
Li, H., Han, X., Liu, Y., Liu, G., Dong, G."Ki67 as a predictor of poor prognosis in patients with triple‑negative breast cancer". Oncology Letters 9, no. 1 (2015): 149-152. https://doi.org/10.3892/ol.2014.2618