Extraskeletal Ewing's sarcoma/primitive neuroectodermal tumor of the mediastinum: Significant response to chemoradiotherapy

Liu,Min; Liu,Bailong; Dong,Lihua; Han,Tao; Zhang,Lei

doi:10.3892/ol.2014.2788

Extraskeletal Ewing's sarcoma/primitive neuroectodermal tumor of the mediastinum: Significant response to chemoradiotherapy

Authors:
- Min Liu
- Bailong Liu
- Lihua Dong
- Tao Han
- Lei Zhang
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Affiliations: Department of Radiation Oncology, The First Hospital, Jilin University, Changchun, Jilin 130021, P.R. China, Department of Radiology, The First Hospital, Jilin University, Changchun, Jilin 130021, P.R. China
Published online on: December 10, 2014 https://doi.org/10.3892/ol.2014.2788
Pages: 626-628
Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary mediastinal extraskeletal Ewing's sarcoma (EES) is quite rare. To the best of our knowledge, only five cases have been reported. Given the paucity of data, there is consequently no optimal treatment strategy available. The current study presents the case of a 51‑year‑old female with unresectable EES of the posterior mediastinum. Chemoradiotherapy achieved near complete remission without severe side‑effects. The literature associated with EES is also reviewed. The present case highlights the possibility of the diagnosis of EES for a mediastinal mass. Chemoradiotherapy may be a good option for unresectable cases. In the future, large‑scale collaborative clinical trials should be initiated to provide an improved understanding of the characteristics of EES and the best treatment strategy.

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