Journal Articles

Open Access

IGF axis and other factors in HPV-related and HPV-unrelated carcinogenesis (Review)

Julia Durzyńska

Pages: 2295-2306 Published online on: 19 September 2014
Open Access

The S100A4 D10V polymorphism is related to cell migration ability but not drug resistance in gastric cancer cells

Tein-Ming Yuan, Ruei-Yue Liang, Nai-Wan Hsiao, Show-Mei Chuang

Pages: 2307-2318 Published online on: 13 October 2014
Open Access

Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models

Nozomu Tanaka, Kazuki Sakamoto, Hiroyuki Okabe, Akio Fujioka, Keisuke Yamamura, Fumio Nakagawa, Hideki Nagase, Tatsushi Yokogawa, Kei Oguchi, Keiji Ishida, Akiko Osada, Hiromi Kazuno, Yukari Yamada, Kenichi Matsuo

Pages: 2319-2326 Published online on: 17 September 2014
Open Access

Global expression profile in low grade meningiomas and schwannomas shows upregulation of PDGFD, CDH1 and SLIT2 compared to their healthy tissue

Miguel Torres-Martin, Luis Lassaletta, Alberto Isla, Jose M. De Campos, Giovanny R. Pinto, Rommel R. Burbano, Javier S. Castresana, Barbara Melendez, Juan A. Rey

Pages: 2327-2334 Published online on: 03 October 2014
Open Access

Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model

Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen

Pages: 2335-2342 Published online on: 13 October 2014
Open Access

Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress

Xia Jiang, Tatsuo Kanda, Shingo  Nakamoto, Yuki  Haga, Reina  Sasaki, Masato Nakamura, Shuang  Wu, Rintaro Mikata, Osamu  Yokosuka

Pages: 2343-2348 Published online on: 06 October 2014
Open Access

Expression of genes encoding extracellular matrix proteins: A macroarray study

Konrad Futyma, Paweł Miotła, Krystyna  Różyńska, Małgorzata Zdunek, Andrzej  Semczuk, Tomasz Rechberger, Jacek Wojcierowski

Pages: 2349-2353 Published online on: 17 September 2014

Circulating miR-199a-3p as a novel serum biomarker for colorectal cancer

Ryoji Nonaka, Junichi Nishimura, Yoshinori Kagawa, Hideki Osawa, Junichi Hasegawa, Kohei Murata, Shu Okamura, Hirofumi Ota, Mamoru Uemura, Taishi Hata, Ichiro Takemasa, Tsunekazu Mizushima, Daisuke Okuzaki, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori

Pages: 2354-2358 Published online on: 24 September 2014

Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow

Masahiro Tawada, Shin-Ichiro Hayashi, Yuka Ikegame, Shigeru Nakashima, Kazuhiro Yoshida

Pages: 2359-2364 Published online on: 19 September 2014

miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma

Kazuo Yamamoto, Masahiro Seike, Susumu Takeuchi, Chie Soeno, Akihiko Miyanaga, Rintaro Noro, Yuji Minegishi, Kaoru Kubota, Akihiko Gemma

Pages: 2365-2372 Published online on: 16 September 2014

Modulated electro-hyperthermia enhances dendritic cell therapy through an abscopal effect in mice

Wei Qin, Yasunori Akutsu, Gabor Andocs, Akiko Suganami, Xin Hu, Gulbostan Yusup, Aki Komatsu-Akimoto, Isamu Hoshino, Naoyuki Hanari, Mikito Mori, Yuka Isozaki, Naoki Akanuma, Yutaka Tamura, Hisahiro Matsubara

Pages: 2373-2379 Published online on: 19 September 2014

Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells

Matthias B. Stope, Martin Weiss, Melanie Preuss, Andreas  Streitbörger, Christoph A. Ritter, Uwe Zimmermann, Reinhard Walther, Martin Burchardt

Pages: 2380-2386 Published online on: 17 September 2014

CXCR7 correlates with the differentiation of hepatocellular carcinoma and suppresses HNF4α expression through the ERK pathway

Tong-Chun Xue, Qing-An Jia, Yang Bu, Rong-Xin Chen, Jie‑Feng Cui, Zhao-You Tang, Sheng-Long Ye

Pages: 2387-2396 Published online on: 19 September 2014

Krüppel-like factor 8 involved in hypoxia promotes the invasion and metastasis of gastric cancer via epithelial to mesenchymal transition

Na Liu, Yafang Wang, Yongan Zhou, Hailin Pang, Jing Zhou, Pei Qian, Lili Liu, Helong Zhang

Pages: 2397-2404 Published online on: 18 September 2014

Development of a 5-fluorouracil-loaded PLGA microsphere delivery system by a solid-in-oil-in-hydrophilic oil (S/O/hO) novel method for the treatment of tumors

Qing Lin, Yunpeng Cai, Minglu Yuan, Lin  Ma, Mingfeng  Qiu, Jing  Su

Pages: 2405-2410 Published online on: 16 September 2014

Adenovirus-mediated siRNA targeting NOB1 inhibits tumor growth and enhances radiosensitivity of human papillary thyroid carcinoma in vitro and in vivo

Wei Meng, Pei-Song Wang, Jia Liu, Shuai Xue, Gui-Min Wang, Xian-Ying Meng, Guang Chen

Pages: 2411-2420 Published online on: 16 September 2014

The mechanisms responsible for the radiosensitizing effects of sorafenib on colon cancer cells

Eun Ho Kim, Mi-Sook Kim, Won-Gyun Jung

Pages: 2421-2428 Published online on: 18 September 2014

Geldanamycin mediates the apoptosis of gastric carcinoma cells through inhibition of EphA2 protein expression

Da-Hu Wang, Yu-Jun Zhang, San-Bing Zhang, Hui Liu, Liang Liu, Feng-Ling Liu, Jing Zuo

Pages: 2429-2436 Published online on: 13 October 2014

Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells

Youlong Zhu, Jiwei Yu, Shoulian Wang, Ruiqi  Lu, Jugang Wu, Bojian Jiang

Pages: 2437-2444 Published online on: 17 September 2014

Allelic loss at chromosome 11q13 alters FGF3 gene expression in a human breast cancer progression model

Debasish Roy, Gloria M. Calaf

Pages: 2445-2452 Published online on: 19 September 2014

Relationship between expression of Livin and the biological behavior of human oral squamous cell carcinoma

Dong Hoon Lee, Tae Mi Yoon, Sun-Ae Kim, Young-Lan Park, Kyung-Hwa Lee, Sang Chul Lim, Joon Kyoo Lee, Young Eun Joο

Pages: 2453-2460 Published online on: 22 September 2014

Induction of apoptosis in MDA-MB-231 human breast carcinoma cells with an ethanol extract of Cyperus rotundus L. by activating caspases

Sang Eun Park, Won Tak Shin, Cheol Park, Su Hyun Hong, Gi-Young Kim, Sung Ok Kim, Chung Ho Ryu, Sang Hoon Hong, Yung Hyun Choi

Pages: 2461-2470 Published online on: 22 September 2014

Expression and roles of fatty acid synthase in hepatocellular carcinoma

Qiwei Hao, Tao Li, Xiong Zhang, Ping Gao, Peiyu Qiao, Sheng Li, Zhimin Geng

Pages: 2471-2476 Published online on: 16 September 2014

Vascular endothelial growth factor plays a critical role in the formation of the pre-metastatic niche via prostaglandin E2

Shili Liu, Man Jiang, Qiang Zhao, Shancheng Li, Yanping Peng, Pengfei Zhang, Mingyong Han

Pages: 2477-2484 Published online on: 24 September 2014

Elevated expression level of long noncoding RNA MALAT-1 facilitates cell growth, migration and invasion in pancreatic cancer

Feng Jiao, Hai Hu, Cuncun Yuan, Lei Wang, Weihua Jiang, Ziliang Jin, Zhen Guo, Liwei Wang

Pages: 2485-2492 Published online on: 26 September 2014

Upregulation of stromal cell-derived factor 1α expression is associated with the resistance to neoadjuvant chemoradiotherapy of locally advanced rectal cancer: Angiogenic markers of neoadjuvant chemoradiation

Han Jo Kim, Sang Byung Bae, Dongjun Jeong, Eun Seog Kim, Chang-Nam Kim, Dong-Guk Park, Tae Sung Ahn, Sung Woo Cho, Eung Jin Shin, Moon Soo Lee, Moo Jun Baek

Pages: 2493-2500 Published online on: 19 September 2014

Synergistic effects of co-expression plasmid‑based ADAM10-specific siRNA and GRIM-19 on hepatocellular carcinoma in vitro and in vivo

Songyang Liu, Wei Zhang, Kai Liu, Yingchao Wang, Bai Ji, Yahui Liu

Pages: 2501-2510 Published online on: 19 September 2014

Restoration of miR-7 expression suppresses the growth of Lewis lung cancer cells by modulating epidermal growth factor receptor signaling

Jingrong Li, Yijie Zheng, Gengyun Sun, Shudao Xiong

Pages: 2511-2516 Published online on: 26 September 2014

Association of p53/p21 expression and cigarette smoking with tumor progression and poor prognosis in non-small cell lung cancer patients

Deyao Xie, Linhua Lan, Kate Huang, Lin Chen, Cuicui Xu, Rongrong Wang, Yang Shi, Xiaoyi Wu, Lu Wang, Yongzhang Liu, Bin Lu

Pages: 2517-2526 Published online on: 10 October 2014

Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9

Chunliu Mi, Hui Shi, Juan Ma, Li Zhuo Han, Jung Joon Lee, Xuejun Jin

Pages: 2527-2532 Published online on: 10 October 2014

SPAG9 expression is increased in human prostate cancer and promotes cell motility, invasion and angiogenesis in vitro

Feifei Chen, Zheng Lu, Junpeng Deng, Xuechao Han, Jin Bai, Qinghua Liu, Yaguang Xi, Junnian Zheng

Pages: 2533-2540 Published online on: 10 October 2014

P-cadherin potentiates ligand-dependent EGFR and IGF-1R signaling in dysplastic and malignant oral keratinocytes

Desseree Lysne, James Johns, Andrew Walker, Rachel Ecker, Christopher Fowler, Kathryn R. Lawson

Pages: 2541-2548 Published online on: 14 October 2014

Regulation of BGC-823 cell sensitivity to adriamycin via miRNA-135a-5p

Yanming Pan, Fengyun Ren, Wei Zhang, Guibo Liu, Dan Yang, Jing Hu, Kejian Feng, Yukuan Feng

Pages: 2549-2556 Published online on: 14 October 2014

Annexin A5 inhibits diffuse large B-cell lymphoma cell invasion and chemoresistance through phosphatidylinositol 3-kinase signaling

Jingjing Wang, Yang Zhang, Xianling Liu, Jinan Ma, Ping Liu, Chunhong Hu, Guangsen Zhang

Pages: 2557-2563 Published online on: 14 October 2014

A new version of targeted minicircle producer system for EBV-positive human nasopharyngeal carcinoma

Yufang Zuo, Sihai Liao, Zumin Xu, Jierong Xie, Wenlin Huang, Zhonghua Yu

Pages: 2564-2570 Published online on: 17 September 2014

Reduced expression of SRY-box containing gene 17 correlates with an unfavorable melanoma patient survival

Jing Lu, Guohong Zhang, Yabin Cheng, Yun Tang, Ziming Dong, Kevin J. McElwee, Gang Li

Pages: 2571-2579 Published online on: 08 October 2014

RUNX3 is inactivated by promoter hypermethylation in malignant transformation of ovarian endometriosis

Cuishan Guo, Fang Ren, Danbo Wang, Yan Li, Kuiran Liu, Shuang Liu, Peng Chen

Pages: 2580-2588 Published online on: 03 October 2014

NAD(P)H:quinone oxidoreductase-1 overexpression predicts poor prognosis in small cell lung cancer

Xuelian Cui, Tiefeng Jin, Xiaoyan Wang, Guang Jin, Zhuhu Li, Lijuan Lin

Pages: 2589-2595 Published online on: 17 September 2014

Metformin inhibits the growth of nasopharyngeal carcinoma cells and sensitizes the cells to radiation via inhibition of the DNA damage repair pathway

Haiwen Li, Xinggui Chen, Ying Yu, Zhennan Wang, Yufang Zuo, Shuhui Li, Donghong Yang, Shengwen Hu, Mei Xiang, Zumin Xu, Zhonghua Yu

Pages: 2596-2604 Published online on: 17 September 2014

Potential role of the OPG/RANK/RANKL axis in prostate cancer invasion and bone metastasis

Xiaoming Li, Yaoming Liu, Bin Wu, Zhilong Dong, Yichen Wang, Jianzhong Lu, Ping Shi, Wenlong Bai, Zhiping Wang

Pages: 2605-2611 Published online on: 23 September 2014

SB365, Pulsatilla saponin D, suppresses the growth of gefitinib-resistant NSCLC cells with Met amplification

Won-Jun Jang, Byoungduck Park, Gil-Saeng  Jeong, Soon-Sun Hong, Chul-Ho Jeong

Pages: 2612-2618 Published online on: 03 October 2014

Membrane-bound complement regulatory proteins are prognostic factors of operable breast cancer treated with adjuvant trastuzumab: A retrospective study

Mei Liu, Ya-Jun Yang, Hong Zheng, Xiao-Rong Zhong, Yu Wang, Zhu Wang, Yao-Geng Wang, Yan-Ping Wang

Pages: 2619-2627 Published online on: 18 September 2014

Loss of ALCAM expression is linked to adverse phenotype and poor prognosis in breast cancer: A TMA-based immunohistochemical study on 2,197 breast cancer patients

Eike Burandt, Tanaz Bari Noubar, Annette Lebeau, Sarah  Minner, Christoph Burdelski, Fritz  Jänicke, Vollkmar  Müller, Luigi  Terracciano, Ronald  Simon, Guido Sauter, Waldemar  Wilczak, Patrick Lebok

Pages: 2628-2634 Published online on: 01 October 2014

Anticancer effects of β-elemene in gastric cancer cells and its potential underlying proteins: A proteomic study

Jun-Song Liu, Shi-Cai He, Zheng-Liang Zhang, Rui Chen, Lin Fan, Guang‑Lin Qiu, Shuai Chang, Liang Li, Xiang-Ming Che

Pages: 2635-2647 Published online on: 17 September 2014

Mechanism and biological significance of the overexpression of IFITM3 in gastric cancer

Jun Hu, Shuwei Wang, Yan Zhao, Qinhao  Guo, Dongsheng  Zhang, Jiejing Chen, Juan  Li, Qiang Fei, Yueming Sun

Pages: 2648-2656 Published online on: 01 October 2014

EphA3, induced by PC-1/PrLZ, contributes to the malignant progression of prostate cancer

Ruiqin Wu, Hongtao Wang, Jian Wang, Peng Wang, Fang Huang, Bangxiang Xie, Yali Zhao, Shanhu Li, Jianguang Zhou

Pages: 2657-2665 Published online on: 16 September 2014

Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells

Sangmin Kim, Won Ho Kil, Jeongmin Lee, Soo-Jin Oh, Jeonghun Han, Myeongjin Jeon, Taewoo Jung, Se Kyung Lee, Soo Youn Bae, Hyun Chul Lee, Jun Ho Lee, Ha Woo Yi, Seok Won Kim, Seok Jin Nam, Jeong Eon Lee

Pages: 2666-2672 Published online on: 24 September 2014

Epithelial-mesenchymal transition in human papillomavirus‑positive and -negative oropharyngeal squamous cell carcinoma

Hiromitsu Hatakeyama, Takatsugu Mizumachi, Tomohiro Sakashita, Satoshi Kano, Akihiro Homma, Satoshi Fukuda

Pages: 2673-2679 Published online on: 22 September 2014

Role of the Wilms' tumor 1 gene in the aberrant biological behavior of leukemic cells and the related mechanisms

Yan Li, Jiying Wang, Xiaoyan Li, Yujiao Jia, Lei Huai, Kan He, Pei Yu, Min Wang, Haiyan Xing, Qing Rao, Zhen Tian, Kejing Tang, Jianxiang Wang, Yingchang Mi

Pages: 2680-2686 Published online on: 06 October 2014

Identification of PAQR3 as a new candidate tumor suppressor in hepatocellular carcinoma

Hong Ge Wu, Wen Jie Zhang, Qian Ding, Gang Peng, Zhen Wei Zou, Ting Liu, Ru Bo Cao, Shi Jiang Fei, Peng Cheng Li, Kun Yu Yang, Jian Li Hu, Xiang Fang Dai, Gang Wu, Pin Dong Li

Pages: 2687-2695 Published online on: 06 October 2014

Knockout of the HCC suppressor gene Lass2 downregulates the expression level of miR-694

Xiaodong Lu, Yuanyuan Chen, Tiantian Zeng, Lufang  Chen, Qixiang Shao, Wenxin Qin

Pages: 2696-2702 Published online on: 03 October 2014

CD38 is highly expressed and affects the PI3K/Akt signaling pathway in cervical cancer

Shan Liao, Songshu Xiao, Guangchao Zhu, Danwei Zheng, Junyu He, Zhen Pei, Guiyuan Li, Yanhong Zhou

Pages: 2703-2709 Published online on: 10 October 2014

Ethyl acetate extract from Jiedu Xiaozheng Yin inhibits the proliferation of human hepatocellular carcinoma cells by suppressing polycomb gene product Bmi1 and Wnt/β-catenin signaling

Xu-Zheng Chen, Zhi-Yun Cao, Jin-Nong Li, Hai-Xia Hu, You-Quan Zhang, Yun-Mei Huang, Zhi-Zhen Liu, Dan Hu, Lian-Ming Liao, Jian Du

Pages: 2710-2718 Published online on: 13 October 2014

Effects of doxorubicin and gemcitabine on the induction of apoptosis in breast cancer cells

Rui-Rui Zheng, Wei Hu, Cheng-Guang Sui, Nan Ma, You-Hong Jiang

Pages: 2719-2725 Published online on: 24 September 2014

Ubiquitin‑specific protease 22‑induced autophagy is correlated with poor prognosis of pancreatic cancer

Jin‑Xiao Liang, Zhen Ning, Wei Gao, Jun Ling, A‑Man Wang, Hai‑Feng Luo, Yong Liang, Qiu Yan, Zhong‑Yu Wang

Pages: 2726-2734 Published online on: 22 September 2014

Mitotic rate is a more reliable unfavorable prognosticator than ulceration for early cutaneous melanoma: A 5-year survival analysis

Piotr Donizy, Maciej Kaczorowski, Marek Leskiewicz, Marcin Zietek, Malgorzata Pieniazek, Cyprian Kozyra, Agnieszka Halon, Rafal Matkowski

Pages: 2735-2743 Published online on: 06 October 2014

microRNA sponge blocks the tumor-suppressing functions of microRNA-122 in human hepatoma and osteosarcoma cells

Ji Ma, Qi Wu, Yue Zhang, Jinghua Li, Yongchun Yu, Qiuhui Pan, Fenyong Sun

Pages: 2744-2752 Published online on: 25 September 2014

Impact of the tumor microenvironment in predicting postoperative hepatic recurrence of pancreatic neuroendocrine tumors

Shoki Sato, Takahiro Tsuchikawa, Toru Nakamura, Nagato  Sato, Eiji  Tamoto, Keisuke Okamura, Toshiaki  Shichinohe, Satoshi Hirano

Pages: 2753-2759 Published online on: 06 October 2014

Activation of STAT3 is involved in malignancy mediated by CXCL12-CXCR4 signaling in human breast cancer

Xiaojian Liu, Qinghuan Xiao, Xuefeng Bai, Zhaojin Yu, Mingli Sun, Haishan Zhao, Xiaoyi Mi, Enhua Wang, Weifan Yao, Feng Jin, Lin Zhao, Jie Ren, Minjie Wei

Pages: 2760-2768 Published online on: 10 October 2014

Tunicamycin-induced ER stress regulates chemokine CCL5 expression and secretion via STAT3 followed by decreased transmigration of MCF-7 breast cancer cells

Yimin Zhang, Shichong Liao, Wei Fan, Wen Wei, Changhua Wang, Shengrong Sun

Pages: 2769-2776 Published online on: 16 September 2014

Berberine hydrochloride IL-8 dependently inhibits invasion and IL-8-independently promotes cell apoptosis in MDA-MB-231 cells

Xiang Li, Shu-Juan Zhao, Hai-Lian Shi, Shui-Ping Qiu, Jian-Qun Xie, Hui Wu, Bei-Bei Zhang, Zheng-Tao Wang, Jian-Ye Yuan, Xiao-Jun Wu

Pages: 2777-2788 Published online on: 30 September 2014

Combination of chloroquine and GX15-070 (obatoclax) results in synergistic cytotoxicity against pancreatic cancer cells

Guan Wang, Shaohua Chen, Holly Edwards, Xinming Cui, Li Cui, Yubin Ge

Pages: 2789-2794 Published online on: 03 October 2014

Fasudil inhibits prostate cancer-induced angiogenesis in vitro

Weihua Chen, Kaili Mao, Thong Hua-Huy, Yihua Bei, Zhongmin Liu, Anh-Tuan Dinh-Xuan

Pages: 2795-2802 Published online on: 17 September 2014

Potentiation of resveratrol-induced apoptosis by matrine in human hepatoma HepG2 cells

Xiuyuan Ou, Yan Chen, Xinxin Cheng, Xumeng Zhang, Qiyang He

Pages: 2803-2809 Published online on: 23 September 2014

Overexpression of syntenin enhances hepatoma cell proliferation and invasion: Potential roles in human hepatoma

Xuemin Liu, Xufeng Zhang, Yi Lv, Junxi Xiang, Jianhua Shi

Pages: 2810-2816 Published online on: 18 September 2014

C5a stimulates the proliferation of breast cancer cells via Akt-dependent RGC-32 gene activation

Yi Lu, Xiao-Bo Hu

Pages: 2817-2823 Published online on: 17 September 2014

MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2

Siliang Wang, Xiaodong Chen, Meiyue Tang

Pages: 2824-2830 Published online on: 15 September 2014

SIRT1 promotes endometrial tumor growth by targeting SREBP1 and lipogenesis

Li Lin, Xiaoxia Zheng, Chunping Qiu, Samina Dongol, Qingtao Lv, Jie Jiang, Beihua Kong, Chenguang Wang

Pages: 2831-2835 Published online on: 01 October 2014

Adrenocortical carcinoma in children: First population‑based clinicopathological study with long-term follow-up

T. M.A. Kerkhofs, M. H.T. Ettaieb, R. H.A. Verhoeven, G. J.L. Kaspers, W. J.E. Tissing, J. Loeffen, M. M. Van den Heuvel-Eibrink, R. R. De Krijger, H. R. Haak

Pages: 2836-2844 Published online on: 22 September 2014

Paeonol exerts an anticancer effect on human colorectal cancer cells through inhibition of PGE2 synthesis and COX-2 expression

Ming Li, Shi-Yun Tan, Xiao-Fan Wang

Pages: 2845-2853 Published online on: 13 October 2014
Journal Cover

December 2014
Volume 32 Issue 6

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2013 Impact Factor: 2.191
Ranked #33/202 Oncology
(total number of cites)

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