Journal Articles

LIM homeobox transcription factors, a novel subfamily which plays an important role in cancer (Review)

Xi Wang, Chao He, Xiaotong Hu

Pages: 1975-1985 Published online on: 27 March 2014

Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma

Yoshiaki Kita, Yuka Nishizono, Hiroshi Okumura, Yasuto Uchikado, Ken Sasaki, Masataka Matsumoto, Tetsuro Setoyama, Kiyonori Tanoue, Itaru Omoto, Shinichiro Mori, Tetsuhiro Owaki, Sumiya Ishigami, Hiroshi Nakagawa, Fumiaki Tanaka, Koshi Mimori, Masaki Mori, Shoji Natsugoe

Pages: 1986-1992 Published online on: 05 March 2014
Open Access

Upregulation of long non-coding RNA urothelial carcinoma associated 1 by CCAAT/enhancer binding protein α contributes to bladder cancer cell growth and reduced apoptosis

Mei Xue, Xu Li, Wenjing Wu, Shuwan Zhang, Shouzhen Wu, Zhengkun Li, Wei Chen

Pages: 1993-2000 Published online on: 19 March 2014

The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells

Yosuke Nakagawa, Atsuhisa Kajihara, Akihisa Takahashi, Natsuko Kondo, Eiichiro Mori, Tadaaki Kirita, Takeo Ohnishi

Pages: 2001-2006 Published online on: 11 March 2014

Non-invasive monitoring of anticancer effects of cisplatin on lung cancer in an orthotopic SCID mouse model using [18F] FDG PET-CT

Mohamed Mokhtar, Kazuya Kondo, Hiromitsu Takizawa, Tamaki Ohtani, Hideki Otsuka, Hitoshi Kubo, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Haruhiko Fujino, Shoji Sakiyama, Akira Tangoku

Pages: 2007-2014 Published online on: 05 March 2014

Nilotinib combined with interleukin-2 mediates antitumor and immunological effects in a B16 melanoma model

K. Geisler, A. Reischer, I. Kroeger, B. Jacobs, K. Meinhardt, R. Bauer, B. Ryffel, A. Mackensen, E. Ullrich

Pages: 2015-2020 Published online on: 10 March 2014

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma

Fei Guo, David Cogdell, Limei Hu, Da Yang, Anil K. Sood, Fengxia Xue, Wei Zhang

Pages: 2021-2028 Published online on: 21 March 2014

MicroRNA expression profiles in supraglottic carcinoma

Tianhong Zhang, Guojun Han, Yansong Wang, Kewa Chen, Yanan Sun

Pages: 2029-2034 Published online on: 27 March 2014

Overexpression of microRNA-143 inhibits growth and induces apoptosis in human leukemia cells

Jian-Zhen Shen, Yuan-Yuan Zhang, Hai-Ying Fu, Dan-Sen Wu, Hua-Rong Zhou

Pages: 2035-2042 Published online on: 11 March 2014

Low expression of GABARAPL1 is associated with a poor outcome for patients with hepatocellular carcinoma

Chao Liu, Yan Xia, Wei Jiang, Yinkun Liu, Long Yu

Pages: 2043-2048 Published online on: 19 March 2014

Eotaxin-1 promotes prostate cancer cell invasion via activation of the CCR3-ERK pathway and upregulation of MMP-3 expression

Feng Zhu, Pei Liu, Jun Li, Yan Zhang

Pages: 2049-2054 Published online on: 05 March 2014

MicroRNA-100 regulates SW620 colorectal cancer cell proliferation and invasion by targeting RAP1B

Hui Peng, Jun Luo, Hu Hao, Jun Hu, Shang-Kui Xie, Donglin Ren, Benqiang Rao

Pages: 2055-2062 Published online on: 11 March 2014

Thymoquinone induces G2/M arrest, inactivates PI3K/Akt and nuclear factor-κB pathways in human cholangiocarcinomas both in vitro and in vivo

Dongsheng Xu, Yong Ma, Baolei Zhao, Shuai Li, Yu Zhang, Shangha Pan, Yaohua Wu, Jizhou Wang, Dawei Wang, Huayang Pan, Lianxin Liu, Hongchi Jiang

Pages: 2063-2070 Published online on: 05 March 2014

MCM7 serves as a prognostic marker in diffuse-type gastric adenocarcinoma and siRNA-mediated knockdown suppresses its oncogenic function

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Alfred S.L. Cheng, Jun Yu, Kafai To

Pages: 2071-2078 Published online on: 19 March 2014

Editing genomic DNA in cancer cells with high genetic variance: Benefit or risk?

Lin Wang, Yixiang Wang, Chuanbin Guo

Pages: 2079-2084 Published online on: 06 March 2014

Suppressive role of miR-502-5p in breast cancer via downregulation of TRAF2

Li-Li Sun, Jian Wang, Zhi-Juan Zhao, Ning Liu, Ai-Lian Wang, Hua-Yan Ren, Fan Yang, Ke-Xin Diao, Wei-Neng Fu, En-Hua Wan, Xiao-Yi Mi

Pages: 2085-2092 Published online on: 21 March 2014

A targeting peptide improves adenovirus-mediated transduction of a glioblastoma cell line

Dongyang Wang, Wenbo Li, Hang Zhang, Qinwen Mao, Haibin Xia

Pages: 2093-2098 Published online on: 06 March 2014

Prostaglandin E2 receptor EP2 mediates Snail expression in hepatocellular carcinoma cells

Shan-Yu Cheng, Hai Zhang, Min Zhang, Shu-Kai Xia, Xiao‑Ming Bai, Li Zhang, Juan Ma, Rong Rong, Yi-Pin Wang, Ming-Zhan Du, Jie Wang, Meng Chen, Feng Shi, Qin-Yi Yang, Jing Leng

Pages: 2099-2106 Published online on: 11 March 2014

Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer

Jiasheng Mu, Haineng Xu, Yu Yang, Weidan Huang, Jing Xiao, Maolan Li, Zhujun Tan, Qichen Ding, Lin Zhang, Jianhua Lu, Xiangsong Wu, Yingbin Liu

Pages: 2107-2114 Published online on: 06 March 2014

Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer

Yuki Seo, Yoshiyuki Ishii, Hiroki Ochiai, Kazumasa Fukuda, Shingo Akimoto, Tetsu Hayashida, Koji Okabayashi, Masashi Tsuruta, Hirotoshi Hasegawa, Yuko Kitagawa

Pages: 2115-2122 Published online on: 11 March 2014

IL-1β-stimulated urokinase plasminogen activator expression through NF-κB in gastric cancer after HGF treatment

Kyung Hee Lee, Eun Young Choi, Sung Ae Koh, Min Kyoung Kim, Byung Ik Jang, Sang Woon Kim, Jae-Ryong Kim

Pages: 2123-2130 Published online on: 12 March 2014

β-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway

Cheng-Cai Yao, Yuan-Rong Tu, Jie Jiang, Sheng-Fang Ye, Hao-Xin Du, Yi Zhang

Pages: 2131-2138 Published online on: 12 March 2014

Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer

Nam Hee Kim, Hye Youn Sung, Eun Nam Choi, Dahyun Lyu, Hyuck Jae Choi, Woong Ju, Jung-Hyuck Ahn

Pages: 2139-2146 Published online on: 24 March 2014

MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment

Chung-Man Leung, Ting-Wen Chen, Sung-Chou Li, Meng-Ru Ho, Ling-Yueh Hu, Wen‑Shan Liu, Tony T. Wu, Ping-Chi Hsu, Hong-Tai Chang, Kuo-Wang Tsai

Pages: 2147-2156 Published online on: 13 March 2014

Coexpression of ANXA2, SOD2 and HOXA13 predicts poor prognosis of esophageal squamous cell carcinoma

Ruo-Lan Ma, Lu-Yan  Shen, Ke-Neng  Chen

Pages: 2157-2164 Published online on: 12 March 2014

STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell carcinoma growth in vitro and in vivo

Xuan Zhou, Yu Ren, Aiqin Liu, Lei Han, Kailiang Zhang, Shasha Li, Peng Li, Ping Li, Chunsheng Kang, Xudong Wang, Lun Zhang

Pages: 2173-2180 Published online on: 27 March 2014

Triptolide-induced in vitro and in vivo cytotoxicity in human breast cancer stem cells and primary breast cancer cells

Junjie Li, Ruilei Liu, Ye Yang, Yong Huang, Xi Li, Ruiming Liu, Xiaoyan Shen

Pages: 2181-2186 Published online on: 27 March 2014

Upregulation of the splice variant MUC4/Y in the pancreatic cancer cell line MIA PaCa-2 potentiates proliferation and suppresses apoptosis: New insight into the presence of the transcript variant of MUC4

Kunling Xie, Xiaofei Zhi, Jie Tang, Yi Zhu, Jingjing Zhang, Zheng Li, Jinqiu Tao, Zekuan Xu

Pages: 2187-2194 Published online on: 27 March 2014

Dosimetric comparison of left-sided whole breast irradiation with 3D-CRT, IP-IMRT and hybrid IMRT

Xiaoxue Xie, Shuyu Ouyang, Hui Wang, Wenjuan Yang, Hekun Jin, Bingqiang Hu, Liangfang Shen

Pages: 2195-2205 Published online on: 05 March 2014

Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker

Jinbang Li, Pinggui Gong, Xiaoming Lyu, Kaitai Yao, Xin Li, Hong Peng

Pages: 2206-2212 Published online on: 05 March 2014

Ki-67 as an independent prognostic factor in an unselected cohort of patients with ovarian cancer: Results of an explorative, retrospective study

Marco Johannes Battista, Nina Mantai, Isabel Sicking, Cristina Cotarelo, Veronika Weyer, Antje Lebrecht, Christine Solbach, Marcus Schmidt

Pages: 2213-2219 Published online on: 11 March 2014

Synergistic effect of nanosecond pulsed electric field combined with low-dose of pingyangmycin on salivary adenoid cystic carcinoma

Wei Qi, Jinsong Guo, Shan Wu, Bo Su, Lei Zhang, Jie Pan, Jue Zhang

Pages: 2220-2228 Published online on: 06 March 2014

Evaluation of premature senescence and senescence biomarkers in carcinoma cells and xenograft mice exposed to single or fractionated irradiation

Bong Cho Kim, Hee Jung Yoo, Hyung Chul Lee, Kyoung-Ah Kang, Seung Hee Jung, Hae-June Lee, Minyoung Lee, Seungwoo Park, Young-Hoon Ji, Yun-Sil Lee, Young-Gyu Ko, Jae-Seon Lee

Pages: 2229-2235 Published online on: 07 March 2014

PTEN mutation, loss of heterozygosity, promoter methylation and expression in colorectal carcinoma: Two hits on the gene?

Maja Hühns, Tareq Salem, Björn Schneider, Mathias Krohn, Michael Linnebacher, Friedrich Prall

Pages: 2236-2244 Published online on: 19 March 2014

L-securinine induces apoptosis in the human promyelocytic leukemia cell line HL-60 and influences the expression of genes involved in the PI3K/AKT/mTOR signaling pathway

Shuwen Han, Gang Zhang, Maidong Li, Dongyun Chen, Ying Wang, Wencai Ye, Zhaoning Ji

Pages: 2245-2251 Published online on: 20 March 2014

Antitumor effect of a selective COX-2 inhibitor, celecoxib, may be attributed to angiogenesis inhibition through modulating the PTEN/PI3K/Akt/HIF-1 pathway in an H22 murine hepatocarcinoma model

Wenwen Sui, Yueying Zhang, Zhaopeng Wang, Zhaoxia Wang, Qing Jia, Licun Wu, Weidong Zhang

Pages: 2252-2260 Published online on: 19 March 2014

MicroRNA-127-3p promotes glioblastoma cell migration and invasion by targeting the tumor-suppressor gene SEPT7

Huawei Jiang, Dasong Hua, Jing Zhang, Qing Lan, Qiang Huang, Jae-Geun Yoon, Xu Han, Lisha Li, Gregory Foltz, Shu Zheng, Biaoyang Lin

Pages: 2261-2269 Published online on: 05 March 2014

Tumor suppressor DLC-1 induces apoptosis and inhibits the growth and invasion of colon cancer cells through the Wnt/β-catenin signaling pathway

Chunyi Wang, Jialin Wang, Hong Liu, Zhongxue Fu

Pages: 2270-2278 Published online on: 05 March 2014

N-myc downstream regulated gene 1 acts as a tumor suppressor in ovarian cancer

Bei Wang, Jianli Li, Zhanying Ye, Zhe Li, Xiaohua Wu

Pages: 2279-2285 Published online on: 11 March 2014

Induction of apoptosis by diphenyldifluoroketone in osteogenic sarcoma cells is associated with activation of caspases

Seok-Jin Yang, Seul Ah Lee, Min-Gyeong Park, Jae-Sung Kim, Sun-Kyoung Yu, Chun Sung Kim, Jin-Soo Kim, Su-Gwan Kim, Ji-Su Oh, Heung-Joong Kim, Hong Sung Chun, Yong Hwan Kim, Do Kyung Kim

Pages: 2286-2292 Published online on: 06 March 2014

Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer

Tao Bai, Dao-Song Dong, Ling Pei

Pages: 2293-2297 Published online on: 14 March 2014

Functional expression of TLR9 in esophageal cancer

Yanli Zhang, Qiuyan Wang, Ailing Ma, Yunhong Li, Rui Li, Yin Wang

Pages: 2298-2304 Published online on: 19 March 2014

Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-κB activity at a safe dose in MCF-7 human breast cancer cells

Min Jeong Kim, Ji Hyun Jung, Won Sup Lee, Jeong Won Yun, Jing Nan Lu, Sang Mi Yi, Hye Jung Kim, Seong-Hwan Chang, Gon-Sup Kim, Soon Chan Hong, Woo Song Ha

Pages: 2305-2311 Published online on: 12 March 2014

SPARC expression is negatively correlated with clinicopathological factors of gastric cancer and inhibits malignancy of gastric cancer cells

Junling Zhang, Pengyuan Wang, Jing Zhu, Wei Wang, Jie Yin, Chi Zhang, Ziyi Chen, Lie Sun, Yuanlian Wan, Xin Wang, Guowei Chen, Yucun Liu

Pages: 2312-2320 Published online on: 27 March 2014

Autophagy promotes the survival and development of tumors by participating in the formation of vasculogenic mimicry

Yun-Peng Ding, Xiao-Dong Yang, Yong Wu, Chun-Gen Xing

Pages: 2321-2327 Published online on: 12 March 2014

Vigilin is overexpressed in hepatocellular carcinoma and is required for HCC cell proliferation and tumor growth

Wen Li Yang, Ling Wei, Wen Qing Huang, Ran Li, Wen Yan Shen, Jian Yu Liu, Jian Ming Xu, Bo Li, Yang Qin

Pages: 2328-2334 Published online on: 24 March 2014

Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells

Jing Kuang, Ya-Lan Wang, Ming Xiao, Yi Tang, Wen‑Wen Chen, Guang-Lin Song, Xi Yang, Ming Li

Pages: 2335-2343 Published online on: 20 March 2014

Knockdown of S100P by lentiviral-mediated RNAi promotes apoptosis and suppresses the colony-formation ability of gastric cancer cells

Qi Zhang, Haolin Hu, Xin Shi, Wenhao Tang

Pages: 2344-2350 Published online on: 21 March 2014

FRZB knockdown upregulates β-catenin activity and enhances cell aggressiveness in gastric cancer

Shuai Qin, Zhuo Zhang, Jianfang Li, Lu Zang

Pages: 2351-2357 Published online on: 24 March 2014

Breast cancer cells are arrested at different phases of the cell cycle following the re-expression of ARHI

Xiaoxiao Zuo, Yan Qin, Xiaojin Zhang, Qian Ning, Shan Shao, Minna Luo, Na Yuan, Shangke Huang, Xinhan Zhao

Pages: 2358-2364 Published online on: 21 March 2014

The role of autophagy induced by pemetrexed in lung adenocarcinoma cells

Ji-Hye Park, Young-Rae Lee, Hong-Seob So, Kang-Kyoo Lee, Sam‑Youn Lee, Sun-Rock Moon, Hyang-Jeong Jo, Seoul Lee, Kyuyong Jeong, Kang-Beom Kwon, Sei-Hoon Yang

Pages: 2365-2370 Published online on: 10 March 2014

Vitamin B6 activates p53 and elevates p21 gene expression in cancer cells and the mouse colon

Peipei Zhang, Sofya Suidasari, Tomomi Hasegawa, Noriyuki Yanaka, Norihisa Kato

Pages: 2371-2376 Published online on: 11 March 2014

Isoquercitrin inhibits the progression of liver cancer in vivo and in vitro via the MAPK signalling pathway

Guihong Huang, Bo Tang, Kun Tang, Xiaomin Dong, Jungang Deng, Luqin Liao, Zengzhen Liao, Hua Yang, Songqing He

Pages: 2377-2384 Published online on: 20 March 2014

Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival

Anna Skalniak, Elżbieta Boratyn, Sylwia D. Tyrkalska, Irena Horwacik, Małgorzata Durbas, Maria Łastowska, Jolanta Jura, Hanna Rokita

Pages: 2385-2392 Published online on: 11 March 2014

Transphosphorylation of EGFR at Y845 plays an important role in its autophosphorylation and kinase activity

Hui Song, Lei Huang, Ming Zhang, Xiuwei Wang, Shuang Song, Lin Yang

Pages: 2393-2398 Published online on: 21 March 2014

Oleanolic acid enhances the radiosensitivity of tumor cells under mimetic hypoxia through the reduction in intracellular GSH content and HIF-1α expression

Rongxin Qi, Wenwen Jin, Juan Wang, Qiyi Yi, Maohu Yu, Shiguo Xu, Wensen Jin

Pages: 2399-2406 Published online on: 06 March 2014

Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer

Roberto Berretta, Tito Silvio Patrelli, Costanza Migliavacca, Martino Rolla, Laura Franchi, Michela Monica, Alberto Bacchi Modena, Salvatore Gizzo

Pages: 2407-2412 Published online on: 21 March 2014

Arecoline inhibits epithelial cell viability by upregulating the apoptosis pathway: Implication for oral submucous fibrosis

Ming Li, Feng Gao, Zhong-Su Zhou, Hui-Ming Zhang, Rui Zhang, Ying-Fang Wu, Ming-Hai Bai, Ji-Jia Li, Shi-Rong Lin, Jie-Ying Peng

Pages: 2422-2428 Published online on: 14 March 2014

Sequential treatment of HPV E6 and E7-expressing TC-1 cells with bortezomib and celecoxib promotes apoptosis through p-p38 MAPK-mediated downregulation of cyclin D1 and CDK2

Jee-Eun Kim, Ji-In Lee, Dong-Hoon Jin, Wang Jae Lee, Ga Bin Park, Seonghan Kim, Yeong Seok Kim, T.-C. Wu, Dae Young Hur, Daejin Kim

Pages: 2429-2437 Published online on: 12 March 2014

Methylation and decreased expression of SHP-1 are related to disease progression in chronic myelogenous leukemia

Yinghua Li, Lin Yang, Yuxia Pan, Jingci Yang, Yintao Shang, Jianmin Luo

Pages: 2438-2446 Published online on: 19 March 2014

Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP‑2 and MMP‑9 via downregulation of NF-κB signaling pathway

Ki Rim Lee, Jong Seok Lee, Young Rae Kim, In Gyu Song, Eock Kee Hong

Pages: 2447-2453 Published online on: 21 March 2014

LAPTM4B polymorphism is associated with non‑small cell lung cancer susceptibility and prognosis

Han Tang, Hui Tian, Weiming Yue, Lin Li, Shuhai Li, Cun Gao, Libo Si, Lei Qi, Ming Lu, Wensi Hu

Pages: 2454-2460 Published online on: 27 March 2014
Journal Cover

May 2014
Volume 31 Issue 5

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2012 Impact Factor: 2.297
Ranked #36/196 Oncology
(total number of cites)

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