Journal Articles

Mitochondrial changes in endometrial carcinoma: Possible role in tumor diagnosis and prognosis (Review)

Antonella Cormio, Gennaro Cormio, Clara Musicco, Anna Maria Sardanelli, Giuseppe Gasparre, Maria Nicola Gadaleta

Pages: 1011-1018 Published online on: 22 December 2014

Statins are potential anticancerous agents (Review)

Abdullah K. Altwairgi

Pages: 1019-1039 Published online on: 20 January 2015
Open Access

A new rapid method for detecting epidermal growth factor receptor mutations in non-small cell lung cancer

Miyako Takata, Hiroki Chikumi, Keiji Matsunami, Masahiro Kodani, Tomohiro Sakamoto, Kazuhiro Hashimoto, Masaki Nakamoto, Kensaku Okada, Tsuyoshi Kitaura, Shingo Matsumoto, Jun Kurai, Akira Yamasaki, Tadashi Igishi, Naoto Burioka, Eiji Shimizu

Pages: 1040-1048 Published online on: 14 January 2015
Open Access

Overexpression of interleukin-18 protein reduces viability and induces apoptosis of tongue squamous cell carcinoma cells by activation of glycogen synthase kinase-3β signaling

Weiwei Liu, Min Hu, Yumei Wang, Baozhen Sun, Yu Guo, Zhimin Xu, Jia Li, Bing Han

Pages: 1049-1056 Published online on: 15 January 2015
Open Access

Salinomycin inhibits hepatocellular carcinoma cell invasion and migration through JNK/JunD pathway-mediated MMP9 expression

Ling Xu, Ting Wang, Wen-Ying Meng, Jue Wei, Jia-Li Ma, Min Shi, Yu-Gang Wang

Pages: 1057-1063 Published online on: 18 December 2014

Upregulated Annexin A1 promotes cellular invasion in triple-negative breast cancer

Maiko Okano, Kensuke Kumamoto, Motonobu Saito, Hisashi Onozawa, Katsuharu Saito, Noriko Abe, Tohru Ohtake, Seiichi Takenoshita

Pages: 1064-1070 Published online on: 14 January 2015

Clinical implication of the preoperative GSA index in 99mTc-GSA scintigraphy in hepatitis C virus-related hepatocellular carcinoma

Hiroki Nishikawa, Yukio Osaki, Hideyuki Komekado, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Akira Arimoto, Ryuichi Kita, Toru Kimura

Pages: 1071-1078 Published online on: 22 December 2014

CDK5RAP1 deficiency induces cell cycle arrest and apoptosis in human breast cancer cell line by the ROS/JNK signaling pathway

Hongbin Wang, Li Wei, Changli Li, Jing Zhou, Zhigao Li

Pages: 1089-1096 Published online on: 20 January 2015

Dickkopf‑3 (Dkk3) induces apoptosis in cisplatin‑resistant lung adenocarcinoma cells via the Wnt/β‑catenin pathway

Zheng Wang, Li‑Jun Ma, Yi Kang, Xiao Li, Xiao‑Ju Zhang

Pages: 1097-1106 Published online on: 30 December 2014

Cycloartan-24-ene-1α,2α,3β-triol, a cycloartane-type triterpenoid from the resinous exudates of Commiphora myrrha, induces apoptosis in human prostatic cancer PC-3 cells

Wenyan Gao, Xiaojie Su, Xiaoyan Dong, Yingli Chen, Chunlan Zhou, Ping Xin, Chunhao Yu, Taiming Wei

Pages: 1107-1114 Published online on: 15 January 2015

microRNA-195 functions as a tumor suppressor by inhibiting CBX4 in hepatocellular carcinoma

Changli Zheng, Jingjing Li, Qi Wang, Wei Liu, Jianda Zhou, Rui Liu, Qinghai Zeng, Xiaowei Peng, Chenghui Huang, Peiguo Cao, Ke Cao

Pages: 1115-1122 Published online on: 19 January 2015

Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells

Mai Sugiyama, Hitoki Hasegawa, Satoko Ito, Kazuya Sugiyama, Masao Maeda, Kosuke Aoki, Toshihiko Wakabayashi, Michinari Hamaguchi, Atsushi Natsume, Takeshi Senga

Pages: 1123-1130 Published online on: 18 December 2014

Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by suppressing cell proliferation

Hiroshi Jikihara, Guangying Qi, Koichiro Nozoe, Mayumi Hirokawa, Hiromi Sato, Yuka Sugihara, Fumio Shimamoto

Pages: 1131-1140 Published online on: 30 December 2014

Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF‑κB‑regulated proteins in A549 human lung cancer cells

Won Sup Lee, Jeong Won Yun, Arulkumar Nagappan, Jing Nan Lu, Min Jeong Kim, Jeong-Hee Lee, Dong Hoon Kim, Yung Hyun Choi, Hye Jung Kim, Ki Churl Chang, Jin-Myung Jung

Pages: 1141-1146 Published online on: 08 December 2014

Silencing of the ABCC4 gene by RNA interference reverses multidrug resistance in human gastric cancer

Guangyu Zhang, Zhenran Wang, Feng Qian, Chen Zhao, Chaowen Sun

Pages: 1147-1154 Published online on: 30 December 2014

RNAi-mediated knockdown of the c-jun gene sensitizes radioresistant human nasopharyngeal carcinoma cell line CNE-2R to radiation

Si-Yan Guo, Xiao-Dong Zhu, Lian-Ying Ge, Song Qu, Ling Li, Fang Su, Ya Guo

Pages: 1155-1160 Published online on: 22 December 2014

Icotinib hydrochloride enhances the effect of radiotherapy by affecting DNA repair in colorectal cancer cells

Hong Ma, Jianping Bi, Tao Liu, Yang Ke, Sheng Zhang, Tao Zhang

Pages: 1161-1170 Published online on: 30 December 2014

Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells

Ji-Hong Moon, Jae-Kyo Jeong, Sang-Youel Park

Pages: 1171-1176 Published online on: 18 December 2014

Silencing XIAP suppresses osteosarcoma cell growth, and enhances the sensitivity of osteosarcoma cells to doxorubicin and cisplatin

Yang Qu, Peng Xia, Shanyong Zhang, Su Pan, Jianwu Zhao

Pages: 1177-1184 Published online on: 23 December 2014

Ubiquitin ligase Siah1 promotes the migration and invasion of human glioma cells by regulating HIF-1α signaling under hypoxia

Hengliang Shi, Bao Zheng, Yuxuan Wu, Yuan Tang, Lei Wang, Yong Gao, Hui Gong, Jin Du, Rutong Yu

Pages: 1185-1190 Published online on: 23 December 2014

(+)‑Terrein inhibits human hepatoma Bel‑7402 proliferation through cell cycle arrest

Fengli Zhang, Meiheriguli Mijiti, Wei Ding, Jiale Song, Ying Yin, Wei Sun, Zhiyong Li

Pages: 1191-1200 Published online on: 14 January 2015

Overexpression of RhoGDI2 correlates with the progression and prognosis of pancreatic carcinoma

Bin Yi, Yi Zhang, Dongming Zhu, Lifeng Zhang, Shiduo Song, Songbing He, Bing Zhang, Dechun Li, Jian Zhou

Pages: 1201-1206 Published online on: 07 January 2015

Wnt3a increases the metastatic potential of non-small cell lung cancer cells in vitro in part via its upregulation of Notch3

Chunyan Li, Gongru Song, Siyang Zhang, Enhua Wang, Zeshi Cui

Pages: 1207-1214 Published online on: 30 December 2014

miRNA‑542‑3p downregulation promotes trastuzumab resistance in breast cancer cells via AKT activation

Tao Ma, Lu Yang, Jin Zhang

Pages: 1215-1220 Published online on: 13 January 2015

MicroRNA-221 accelerates the proliferation of laryngeal cancer cell line Hep-2 by suppressing Apaf-1

Xin Sun, Bin Liu, Xu-Dong Zhao, Li-Yin Wang, Wen-Yue Ji

Pages: 1221-1226 Published online on: 13 January 2015

Misregulation of polo-like protein kinase 1, P53 and P21WAF1 in epithelial ovarian cancer suggests poor prognosis

Ruitao Zhang, Huirong Shi, Fang Ren, Huina Liu, Minghui Zhang, Youxing Deng, Xia Li

Pages: 1235-1242 Published online on: 15 January 2015

A novel PALB2 truncating mutation in an Italian family with male breast cancer

Maria Teresa Vietri, Gemma Caliendo, Amelia Casamassimi, Michele Cioffi, Maria Laura De Paola, Claudio Napoli, Anna Maria Molinari

Pages: 1243-1247 Published online on: 22 December 2014

Multiple antigenic polypeptide composed of heparanase B‑cell epitopes shrinks human hepatocellular carcinoma in mice

Jun Zhang, Jianmin Yang, Yuan Cai, Ni Jin, Huiju Wang, Tong Yu

Pages: 1248-1256 Published online on: 18 December 2014

Sphingosine kinase 1 enhances the invasion and migration of non-small cell lung cancer cells via the AKT pathway

Liangming Zhu, Zhou Wang, Yuxia Lin, Zhitao Chen, Haibo Liu, Ying Chen, Ningning Wang, Xiue Song

Pages: 1257-1263 Published online on: 19 December 2014

Nitidine chloride induces apoptosis in human hepatocellular carcinoma cells through a pathway involving p53, p21, Bax and Bcl-2

Xianhong Ou, You Lu, Liufeng Liao, Danni Li, Limin Liu, Huagang Liu, Heng Xu

Pages: 1264-1274 Published online on: 22 December 2014

MicroRNA-10b is upregulated and has an invasive role in colorectal cancer through enhanced Rhoc expression

Yun-Feng Wang, Zhen Li, Xu-Hong Zhao, Xiao-Ming Zuo, Yong Zhang, Yi-Hua Xiao, Jian Li, Zhi-Hai Peng

Pages: 1275-1283 Published online on: 20 January 2015

Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-κB signaling

Hongxia Cui, Jiaxin Yuan, Xiaohui Du, Ming Wang, Liling Yue, Jicheng Liu

Pages: 1284-1290 Published online on: 18 December 2014

miR-142 acts as a tumor suppressor in osteosarcoma cell lines by targeting Rac1

Zhonghui Zheng, Muliang Ding, Jiangdong Ni, Deye Song, Jun Huang, Junjie Wang

Pages: 1291-1299 Published online on: 22 December 2014

Nucleosome-binding protein HMGN2 exhibits antitumor activity in human SaO2 and U2-OS osteosarcoma cell lines

Guojun Liang, Enjie Xu, Chaoqun Yang, Chenglin Zhang, Xiaolong Sheng, Xuhui Zhou

Pages: 1300-1306 Published online on: 22 December 2014

Combination of HSV1-TK/shTERT by retrovirus vector inhibits hepatocellular carcinoma cell growth in vitro and in vivo

Hongsheng Li, Qiaoyu Wang, Dongli Li, Quanshi Wang, Hubing Wu

Pages: 1307-1313 Published online on: 23 December 2014

A longitudinal study of CEACAM1 expression in melanoma disease progression

Douglas Zippel, Hani Barlev, Rona Ortenberg, Iris Barshack, Jacob Schachter, Gal Markel

Pages: 1314-1318 Published online on: 30 December 2014

Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia cells

Yong Zhuang, Yuanyuan Lu, Dong Li, Nianzheng Sun, Xiuli Ju

Pages: 1319-1325 Published online on: 18 December 2014

Clinical and tumor significance of tropomyosin-1 expression levels in renal cell carcinoma

Jin Wang, Jingjing Guan, Zhihua Lu, Jingji Jin, Yong Cai, Chunxi Wang, Fei Wang

Pages: 1326-1334 Published online on: 19 January 2015

p53-induced microRNA-1246 inhibits the cell growth of human hepatocellular carcinoma cells by targeting NFIB

Quan Zhang, Li-Ye Cao, Shu-Jie Cheng, Ai-Min Zhang, Xiao-Shi Jin, Yong Li

Pages: 1335-1341 Published online on: 14 January 2015

MicroRNA‑135b regulates the stability of PTEN and promotes glycolysis by targeting USP13 in human colorectal cancers

Shijun Xiang, Jiaqing Fang, Shuyun Wang, Biao Deng, Lin Zhu

Pages: 1342-1348 Published online on: 23 December 2014

Decreased expression of sestrin 2 predicts unfavorable outcome in colorectal cancer

Jin‑Lai Wei, Zhong‑Xue Fu, Min Fang, Jin‑Bao Guo, Qing‑Ning Zhao, Wei‑Dong Lu, Qiu‑Yuan Zhou

Pages: 1349-1357 Published online on: 30 December 2014

Recombinant hirudin suppresses the viability, adhesion, migration and invasion of Hep-2 human laryngeal cancer cells

Qian Lu, Mei Lv, Erdong Xu, Fangyu Shao, Ya Feng, Jingru Yang, Lin Shi

Pages: 1358-1364 Published online on: 14 January 2015

Kinesin superfamily protein 17 contributes to the development of bone cancer pain by participating in NR2B transport in the spinal cord of mice

Ming Liu, Yue Liu, Bailing Hou, Dan Bu, Linyu Shi, Xiaoping Gu, Zhengliang Ma

Pages: 1365-1371 Published online on: 07 January 2015

Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma: The effect is autophagy-associated

Shuai Liu, Fang Xie, Hafeng Wang, Zheng Liu, Xiaowen Liu, Liang Sun, Zhihong Niu

Pages: 1372-1380 Published online on: 23 December 2014

Effect of local treatment with adipose tissue-derived mesenchymal stem cells in the early tumorigenesis of osteosarcoma

Sheen-Woo Lee, Tae Joo Jeon, Sandip Biswal

Pages: 1381-1387 Published online on: 08 January 2015

Inhibitory action of pristimerin on hypoxia‑mediated metastasis involves stem cell characteristics and EMT in PC-3 prostate cancer cells

Jianwei Zuo, Yuanqing Guo, Xinsheng Peng, Yubo Tang, Xintao Zhang, Peiheng He, Shuaihua Li, Qingde Wa, Jinglei Li, Shuai Huang, Dongliang Xu

Pages: 1388-1394 Published online on: 07 January 2015

Combined treatment with ABT-737 and VX-680 induces apoptosis in Bcl-2- and c-FLIP-overexpressing breast carcinoma cells

Jung Eun Choi, Seon Min Woo, Kyoung-Jin Min, Su Hwan Kang, Soo Jung Lee, Taeg Kyu Kwon

Pages: 1395-1401 Published online on: 15 January 2015

microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer

Xiao-Wei Wang, Xue-Qin Xi, Jian Wu, Yi-Yuan Wan, Hong-Xia Hui, Xiu-Feng Cao

Pages: 1402-1410 Published online on: 19 January 2015

Molecular markers to assess short-term disease local recurrence in nasopharyngeal carcinoma

Tao Xu, Bojin Su, Chunhua Wang, Sumei Wang, Hecheng Huang, Yunbao Pan, Donghui Wang, Weihong Wei, François X. Claret, Huiling Yang

Pages: 1418-1426 Published online on: 20 January 2015

Downregulation of peroxiredoxin-1 by β-elemene enhances the radiosensitivity of lung adenocarcinoma xenografts

Guoquan Li, Bingbing Xie, Xiaolong Li, Yinghai Chen, Yinghui Xu, Meng Xu-Welliver, Lijuan Zou

Pages: 1427-1433 Published online on: 19 January 2015

Diphenylene iodonium interferes with cell cycle progression and induces apoptosis by modulating NAD(P)H oxidase/ROS/cell cycle regulatory pathways in Burkitt's lymphoma cells

Ya Ding, Wenjun Zhu, Rui Sun, Gang Yuan, Dongsheng Zhang, Yuhua Fan, Jian Sun

Pages: 1434-1442 Published online on: 15 January 2015

Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway

Umawadee Laothong, Yusuke Hiraku, Shinji Oikawa, Kitti Intuyod, Mariko Murata, Somchai Pinlaor

Pages: 1443-1449 Published online on: 20 January 2015

Effect of the knockdown of death-associated protein 1 expression on cell adhesion, growth and migration in breast cancer cells

Umar Wazir, Andrew J. Sanders, Ali Wazir, Ruqia Mehmood Baig, Wen G. Jiang, Irina C. Ster, Anup K. Sharma, Kefah Mokbel

Pages: 1450-1458 Published online on: 22 December 2014

NRSF/REST regulates the mTOR signaling pathway in oral cancer cells

Eugene Cho, Sung-Min Moon, Bo Ram Park, Do Kyung Kim, Byung-Kwon Lee, Chun Sung Kim

Pages: 1459-1464 Published online on: 18 December 2014

Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function

Liangyu Chen, Xinxing Li, Libo Liu, Bo Yu, Yixue Xue, Yunhui Liu

Pages: 1465-1474 Published online on: 13 January 2015

Anti-estrogen‑resistant breast cancer cells are sensitive to cisplatin plus TRAIL treatment

Shuping Yin, Arun K. Rishi, Kaladhar B. Reddy

Pages: 1475-1480 Published online on: 14 January 2015

Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma

Heyun Zhang, Wenbin Li, Pinbo Huang, Lehang Lin, Hua Ye, Dechen Lin, H. Phillip Koeffler, Jie Wang, Dong Yin

Pages: 1481-1492 Published online on: 08 January 2015

STAT3 regulates the migration and invasion of a stem‑like subpopulation through microRNA‑21 and multiple targets in hepatocellular carcinoma

Ning Zhang, Wei‑Dong Duan, Jian‑Jun Leng, Liang Zhou, Xing Wang, Yin‑Zhe Xu, Xue‑Dong Wang, Ai‑Qun Zhang, Jia‑Hong Dong

Pages: 1493-1498 Published online on: 08 January 2015

Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors

Shinsuke Hashida, Hiromasa Yamamoto, Kazuhiko Shien, Tomoaki Ohtsuka, Ken Suzawa, Yuho Maki, Masashi Furukawa, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Susumu Kanazawa, Shinichi Toyooka

Pages: 1499-1504 Published online on: 20 January 2015

PKA/CREB regulates the constitutive promoter activity of the USP22 gene

Jianjun Xiong, Xiaoou Zhou, Zhen Gong, Ting Wang, Chao Zhang, Xiaoyuan Xu, Jianyun Liu, Weidong Li

Pages: 1505-1511 Published online on: 20 January 2015

Beneficial effect of T follicular helper cells on antibody class switching of B cells in prostate cancer

Jiufeng Tan, Xuefei Jin, Rui Zhao, Xin Wei, Yan Liu, Xiangbo Kong

Pages: 1512-1518 Published online on: 19 December 2014

Expression of oncogenic HMGN5 increases the sensitivity of prostate cancer cells to gemcitabine

Zhongqiang Guo, Xiaoyu Zhang, Xuesong Li, Feng Xie, Boxing Su, Min Zhang, Liqun Zhou

Pages: 1519-1525 Published online on: 23 December 2014

A novel bispidinone analog induces S‑phase cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells

Xu Yi, Xin Zhang, Hyunjin Jeong, Yu Mi Shin, Dong Ho Park, Song You, Dong-Kyoo Kim

Pages: 1526-1532 Published online on: 15 January 2015

Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis

Feng Gao, Ming Li, Wen-Bin Liu, Zhong-Su Zhou, Rui Zhang, Jun-Ling Li, Ke-Chao Zhou

Pages: 1533-1539 Published online on: 15 January 2015

Silencing NOB1 enhances doxorubicin antitumor activity of the papillary thyroid carcinoma in vitro and in vivo

Jia Liu, Bing-Fei Dong, Pei-Song Wang, Pei-You Ren, Shuai Xue, Xiao-Νan Zhang, Zhe Han, Guang Chen

Pages: 1551-1559 Published online on: 15 January 2015

Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway

Zhaojun Wan, Huazheng Pan, Shihai Liu, Jingjuan Zhu, Weiwei Qi, Kai Fu, Teng Zhao, Jun Liang

Pages: 1560-1566 Published online on: 20 January 2015
Journal Cover

March 2015
Volume 33 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2013 Impact Factor: 2.191
Ranked #33/202 Oncology
(total number of cites)

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