Journal Articles

Antibody therapies for melanoma: New and emerging opportunities to activate immunity (Review)

Sadek Malas, Micaela Harrasser, Katie E. Lacy, Sophia N. Karagiannis

Pages: 875-886 Published online on: 20 June 2014
Open Access

Impact of 5-fluorouracil metabolizing enzymes on chemotherapy in patients with resectable colorectal cancer

Takumi Ochiai, Masahiko Umeki, Hiroshi Miyake, Tatsumi Iida, Minoru Okumura, Kazuhide Ohno, Masashi Sakamoto, Nobukazu Miyoshi, Masahiko Takahashi, Hidenori Tsumura, Yukihiko Tokunaga, Haruhiko Naitou, Takuji Fukui

Pages: 887-892 Published online on: 02 July 2014
Open Access

IGF expression in HPV-related and HPV-unrelated human cancer cells

Julia Durzyńska, Elisabeth Barton

Pages: 893-900 Published online on: 11 July 2014
Open Access

Aurora kinase A is a possible target of OSU‑03012 to destabilize MYC family proteins

Andres Silva, Jennie Wang, Sarah Lomahan, Tuan-Anh Tran, Laura Grenlin, Akiko Suganami, Yutaka Tamura, Naohiko Ikegaki

Pages: 901-905 Published online on: 11 July 2014
Open Access

Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms

Sven-Petter Haugvik, Ludmila Gorunova, Lisbeth Haugom, Anne  Mette Eibak, Ivar Prydz Gladhaug, Sverre Heim, Francesca Micci

Pages: 906-912 Published online on: 11 July 2014
Open Access

GPC3 expression in mouse ovarian cancer induces GPC3‑specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth

Chenhong Luo, Kiyosumi Shibata, Shiro Suzuki, Hiroaki Kajiyama, Takeshi  Senga, Yoshihiro Koya, Mina Daimon, Mamoru Yamashita, Fumitaka Kikkawa

Pages: 913-921 Published online on: 02 July 2014

New enhanced and effective method for staging cancer to detect lymph nodes after fat-dissociation

Shiki Fujino, Norikatsu Miyoshi, Masayuki  Ohue, Shingo  Noura, Yasuhiko  Tomita, Masahiko  Yano, Masato Sakon

Pages: 922-926 Published online on: 09 July 2014

Altered expression of ETV1 and its contribution to tumorigenic phenotypes in gastrointestinal stromal tumors

Yan Zhang, Meng-Li Gu, Xin-Xin  Zhou, Han  Ma, Hang-Ping  Yao, Feng Ji

Pages: 927-934 Published online on: 23 June 2014

Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia

Haitao Zhu, Dongqing  Wang, Lirong  Zhang, Xiaodong  Xie, Yingying  Wu, Yanfang  Liu, Genbao  Shao, Zhaoliang  Su

Pages: 935-942 Published online on: 02 July 2014

An ovarian cancer model with positive ER: Reversion of ER antagonist resistance by Src blockade

Long Li, Xiaojun Li, Xiaobing Han, Ting Yang, Jing  Fu, Yunfeng Zhang, Wenli Gou

Pages: 943-950 Published online on: 23 June 2014

Downregulation of microRNA-155 accelerates cell growth and invasion by targeting c-myc in human gastric carcinoma cells

Shibo Sun, Peng  Sun, Chunmei  Wang, Tiewei  Sun

Pages: 951-956 Published online on: 24 June 2014

miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma

Xiaoling She, Zhibin Yu, Yulong Cui, Qianqian Lei, Zeyou Wang, Gang Xu, Juanjuan Xiang, Minghua Wu, Guiyuan Li

Pages: 957-964 Published online on: 10 July 2014

Knockdown of CXCR7 inhibits proliferation and invasion of osteosarcoma cells through inhibition of the PI3K/Akt and β-arrestin pathways

Yong Zhang, Chao-Qun Yang, Yang  Gao, Ce  Wang, Cheng-Lin Zhang, Xu-Hui Zhou

Pages: 965-972 Published online on: 25 June 2014

Downregulation of HNF1 homeobox B is associated with drug resistance in ovarian cancer

Jianchao Li, Yonghong Zhang, Yutao  Gao, Yuqian  Cui, Hua Liu, Mi Li, Yongjie  Tian

Pages: 979-988 Published online on: 27 June 2014

Expression of the adaptor protein Tks5 in human cancer: Prognostic potential

Stanley S. Stylli, Rodney B. Luwor, Andrew H. Kaye, Stacey  T.T. I, Christopher M. Hovens, Peter  Lock

Pages: 989-1002 Published online on: 04 July 2014

Expression of miR-224-5p is associated with the original cisplatin resistance of ovarian papillary serous carcinoma

Henan Zhao, Tie Bi, Zhenyun Qu, Jiyong  Jiang, Shiying  Cui, Yan Wang

Pages: 1003-1012 Published online on: 07 July 2014

Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells

Yunyuan Zhang, Xian Chen, Min Qiao, Bing-Qiang Zhang, Ning Wang, Zhonglin Zhang, Zhan Liao, Liyi Zeng, Youlin Deng, Fang Deng, Junhui Zhang, Liangjun Yin, Wei Liu, Qian Zhang, Zhengjian Ya, Jixing Ye, Zhongliang Wang, Lan Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, Hongyu Zhang

Pages: 1013-1020 Published online on: 03 July 2014

MicroRNA-451 regulates activating transcription factor 2 expression and inhibits liver cancer cell migration

Guixiang Lv, Zheng Hu, Yi Tie, Jingli Du, Hanjiang Fu, Xu Gao, Xiaofei Zheng

Pages: 1021-1028 Published online on: 27 June 2014

MicroRNA-1290 promotes asiatic acid‑induced apoptosis by decreasing BCL2 protein level in A549 non‑small cell lung carcinoma cells

Ki Bbeum Kim, Karam Kim, Seunghee Bae, Yeonghmin Choi, Hwa Jun Cha, Soo Yeon Kim, Jae Ho Lee, So Hyeon Jeon, Ho Jung Jung, Kyu Joong Ahn, In-Sook An, Sungkwan An

Pages: 1029-1036 Published online on: 10 July 2014

Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21

Bing Hu, Qin Du, Shan Deng, Hong-Mei  An, Chuan-Fang  Pan, Ke‑Ping  Shen, Ling  Xu, Meng-Meng Wei, Shuang-Shuang Wang

Pages: 1037-1042 Published online on: 07 July 2014

Expression of neighbor of Punc E11 in hepatocarcinogenesis induced by diethylnitrosamine

Young Hee Kim, Kyung A Kwak, Jin Seok Kang

Pages: 1043-1049 Published online on: 23 June 2014

Lin28/let-7/Bcl-xL pathway: The underlying mechanism of drug resistance in Hep3B cells

Nan Tian, Ziwu Han, Zhaohui Li, Mingjie  Zhou, Chunlei  Fan

Pages: 1050-1056 Published online on: 25 June 2014

Vitamin C enhances anticancer activity in methotrexate‑treated Hep3B hepatocellular carcinoma cells

Giou-Teng Yiang, Pei-Lun Chou, Yu-Ting Hung, Jen-Ni Chen, Wei-Jung Chang, Yung-Luen Yu, Chyou-Wei Wei

Pages: 1057-1063 Published online on: 25 June 2014

Effect of the downregulation of SMYD3 expression by RNAi on RIZ1 expression and proliferation of esophageal squamous cell carcinoma

Shang-Wen Dong, Hao Zhang, Bao-Li  Wang, Pei  Sun, Yuan-Guo  Wang, Peng Zhang

Pages: 1064-1070 Published online on: 03 July 2014

ZNF703 promotes tumor cell proliferation and invasion and predicts poor prognosis in patients with colorectal cancer

Feng Ma, Lihong Bi, Gongli Yang, Mengnan Zhang, Cuiping Liu, Yingying Zhao, Yadong Wang, Jide Wang, Yang Bai, Yali Zhang

Pages: 1071-1077 Published online on: 07 July 2014

Identification of ApoA1, HPX and POTEE genes by omic analysis in breast cancer

Naci Cine, Ahmet Tarik Baykal, Deniz Sunnetci, Zafer  Canturk, Muge  Serhatli, Hakan  Savli

Pages: 1078-1086 Published online on: 23 June 2014

Matrine induces the apoptosis of lung cancer cells through downregulation of inhibitor of apoptosis proteins and the Akt signaling pathway

Huiyan Niu, Yifei Zhang, Baogang Wu, Yi Zhang, Hongfang Jiang, Ping He

Pages: 1087-1093 Published online on: 20 June 2014

Artemisinin reduces cell proliferation and induces apoptosis in neuroblastoma

Shunqin Zhu, Wanhong Liu, Xiaoxue Ke, Jifu Li, Renjian Hu, Hongjuan Cui, Guanbin Song

Pages: 1094-1100 Published online on: 11 July 2014

Aberrant expression of enhancer of zeste homologue 2, correlated with HIF-1α, refines relapse risk and predicts poor outcome for breast cancer

Min Dong, Xin-Juan Fan, Zhan-Hong Chen, Tian-Tian Wang, Xing Li, Jie  Chen, Qu Lin, Jing-Yun Wen, Xiao-Kun Ma, Li Wei, Dan-Yun Ruan, Ze-Xiao Lin, Quentin Liu, Xiang-Yuan Wu, Xiang-Bo Wan

Pages: 1101-1107 Published online on: 10 July 2014

Effect of DJ-1 overexpression on the proliferation, apoptosis, invasion and migration of laryngeal squamous cell carcinoma SNU-46 cells through PI3K/AKT/mTOR

Bin Wang, Hao Qin, Yuejian  Wang, Weixiong  Chen, Jie  Luo, Xiaolin Zhu, Weiping  Wen, Wenbin Lei

Pages: 1108-1116 Published online on: 24 June 2014

Tussilago farfara L. augments TRAIL-induced apoptosis through MKK7/JNK activation by inhibition of MKK7‑TIPRL in human hepatocellular carcinoma cells

Hyo-Jung Lee, Hyun-Soo Cho, Soo  Young Jun, Jeong-Ju  Lee, Ji‑Yong  Yoon, Jae-Hye  Lee, Hyuk‑Hwan Song, Sang  Ho Choi, Soo‑Yong  Kim, Vassiliki Saloura, Choon  Gil Park, Nam-Soon Kim

Pages: 1117-1123 Published online on: 23 June 2014

S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells

Dandan Tong, Hui Qu, Xiangning Meng, Yang Jiang, Duanyang Liu, Shengqian Ye, He Chen, Yan Jin, Songbin Fu, Jingshu Geng

Pages: 1124-1132 Published online on: 26 June 2014

Establishment and characterization of a cisplatin‑resistant human osteosarcoma cell line

Tao Han, Xiaoming Zhu, Julei Wang, Haien Zhao, Qiong Ma, Jian Zhao, Xiuchun Qiu, Qingyu Fan

Pages: 1133-1139 Published online on: 07 July 2014

Cyclooxygenase-2 inhibition as a strategy for treating gastric adenocarcinoma

Hong-Gang Xiang, Xiao Xie, Feng-Qing Hu, Hai-Bo Xiao, Wen-Jie Zhang, Lei Chen

Pages: 1140-1148 Published online on: 02 July 2014

Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-κB pathway

Cheng-Lin Zhang, Ce Wang, Wang-Jun  Yan, Rui Gao, Yong-Hua  Li, Xu-Hui Zhou

Pages: 1149-1155 Published online on: 25 June 2014

β3GnT8 plays an important role in CD147 signal transduction as an upstream modulator of MMP production in tumor cells

Zhi Jiang, Shuijun Hu, Dong Hua, Jianlong Ni, Lan Xu, Yan  Ge, Yinghui Zhou, Zhihong Cheng, Shiliang Wu

Pages: 1156-1162 Published online on: 23 June 2014

Downregulation of fibroblast growth factor receptor 2 and its isoforms correlates with a high proliferation rate and poor prognosis in high-grade glioma

Ryuji Ohashi, Yoko Matsuda, Toshiyuki Ishiwata, Zenya Naito

Pages: 1163-1169 Published online on: 23 June 2014

Knockdown of nuclear factor erythroid 2-related factor 2 by lentivirus induces differentiation of glioma stem-like cells

Jianhong Zhu, Handong Wang, Youwu Fan, Yangchun  Hu, Xiangjun Ji, Qing Sun, Huandong Liu

Pages: 1170-1178 Published online on: 10 July 2014

Wogonoside induces autophagy-related apoptosis in human glioblastoma cells

Li Zhang, Handong Wang, Zixiang Cong, Jianguo Xu, Jianhong Zhu, Xiangjun Ji, Ke Ding

Pages: 1179-1187 Published online on: 26 June 2014

Cetuximab inhibits cisplatin-induced activation of EGFR signaling in esophageal squamous cell carcinoma

Junhye Kwon, Hyeon-Joon Yoon, Ji-Hee Kim, Tae Sup Lee, In Ho Song, Hae Won Lee, Moon Chul Kang, Jong Ho Park

Pages: 1188-1192 Published online on: 03 July 2014

MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A

Wenwei Ye, Jisen Xue, Qian Zhang, Fuyao Li, Wei Zhang, Huijun Chen, Yibo Huang, Feiyun Zheng

Pages: 1193-1199 Published online on: 03 July 2014

Bioinformatics analysis identifies miR-221 as a core regulator in hepatocellular carcinoma and its silencing suppresses tumor properties

Xing-Xing He, An-Yuan  Guo, Chuan-Rui  Xu, Ying  Chang, Guang-Ya  Xiang, Jing  Gong, Zi-Li  Dan, De-An Tian, Jia-Zhi Liao, Ju-Sheng Lin

Pages: 1200-1210 Published online on: 03 July 2014

The novel bis-benzylisoquinoline PY35 reverses P-glycoprotein-mediated multidrug resistance

Zhonglian Cao, Meredith Wright, Jiekai Cheng, Xiaoxing  Huang, Li Liu, Lixing Wu, Ping Yang

Pages: 1211-1217 Published online on: 11 July 2014

Neuregulin-1 induces cancer stem cell characteristics in breast cancer cell lines

Hoiseon Jeong, Jinkyoung Kim, Youngseok Lee, Jae Hong Seo, Sung Ran Hong, Aeree Kim

Pages: 1218-1224 Published online on: 11 July 2014

Insulin receptor substrate-1 and Golgi phosphoprotein 3 are downstream targets of miR‑126 in esophageal squamous cell carcinoma

Haomiao Li, Fanyu Meng, Jun Ma, Yongkui Yu, Xionghuai Hua, Jianjun Qin, Yin Li

Pages: 1225-1233 Published online on: 11 July 2014

TNF-related apoptosis-inducing ligand enhances vinorelbine-induced apoptosis and antitumor activity in a preclinical model of non-small cell lung cancer

Kunshou Zhu, Weimin Fang, Yuanmei  Chen, Shaofeng  Lin, Xiaohui Chen

Pages: 1234-1242 Published online on: 11 July 2014

RRR-α-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-κB signaling pathway

Yanpei Sun, Yan Zhao, Liying Hou, Xuguang Zhang, Zhihong Zhang, Kun Wu

Pages: 1243-1248 Published online on: 23 June 2014

MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31

Chaoyin Jiang, Hua Chen, Lei Shao, Qiaojie Wang

Pages: 1249-1256 Published online on: 20 June 2014

CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells

Yan-Jin Liu, Ying-Chao Lin, Jang-Chang Lee, Sheng-Chu Kuo, Chi-Tang Ho, Li-Jiau Huang, Daih-Huang Kuo, Tzong-Der Way

Pages: 1257-1264 Published online on: 10 July 2014

Knockdown of YAP1 inhibits the proliferation of osteosarcoma cells in vitro and in vivo

Zhi Yang, Ming Zhang, Ke Xu, Lin Liu, Wei-Kun Hou, Yuan-Zhen Cai, Peng Xu, Jian-Feng Yao

Pages: 1265-1272 Published online on: 03 July 2014

E2F1 acts as a negative feedback regulator of c-Myc‑induced hTERT transcription during tumorigenesis

Yafei Zhang, Anran Zhang, Caifei Shen, Bicheng Zhang, Zhiguo Rao, Rongquan Wang, Shiming Yang, Shoubin Ning, Gaoping Mao, Dianchun Fang

Pages: 1273-1280 Published online on: 24 June 2014

Long non-coding RNA urothelial carcinoma associated 1 induces cell replication by inhibiting BRG1 in 5637 cells

Xiujuan Wang, Yanbing Gong, Bo  Jin, Chenglin  Wu, Jianming  Yang, Le  Wang, Zheng  Zhang, Zebin Mao

Pages: 1281-1290 Published online on: 03 July 2014

Heat shock protein 20 (HSPB6) regulates apoptosis in human hepatocellular carcinoma cells: Direct association with Bax

Tomoaki Nagasawa, Rie Matsushima-Nishiwaki, Hidenori Toyoda, Junya Matsuura, Takashi Kumada, Osamu Kozawa

Pages: 1291-1295 Published online on: 23 June 2014

Galium verum aqueous extract strongly inhibits the motility of head and neck cancer cell lines and protects mucosal keratinocytes against toxic DNA damage

Marianne Schmidt, Christine Polednik, Jeanette  Roller, Rudolf Hagen

Pages: 1296-1302 Published online on: 09 July 2014

Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells

Liuqi Yang, Huijie Guo, Lihua Dong, Li Wang, Chunlan Liu, Xiujie Wang

Pages: 1303-1311 Published online on: 26 June 2014

TRAF4 promotes tumorigenesis of breast cancer through activation of Akt

Jie Zhang, Xiaorui Li, Weilong Yang, Xiaokui Jiang, Na Li

Pages: 1312-1318 Published online on: 03 July 2014

[Corrigendum] miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11

Huanjiang Niu, Kun Wang, Anling Zhang, Shuxu Yang, Zhengfei Song, Wei Wang, Cong Qian, Xinwei Li, Yinxin Zhu, Yirong Wang

Pages: 1319-1319 Published online on: 10 July 2014
Journal Cover

September 2014
Volume 32 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2012 Impact Factor: 2.191
Ranked #33/202 Oncology
(total number of cites)

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