Journal Articles

Open Access

Genetics, diagnosis and management of colorectal cancer (Review)

Marina De Rosa, Ugo Pace, Daniela Rega, Valeria Costabile, Francesca Duraturo, Paola Izzo, Paolo Delrio

Pages: 1087-1096 Published online on: 03 July 2015

Nanotechnology applications in hematological malignancies (Review)

Ahmed Samir, Basma M. Elgamal, Hala Gabr, Hatem E. Sabaawy

Pages: 1097-1105 Published online on: 02 July 2015
Open Access

Natural and adaptive IgM antibodies in the recognition of tumor-associated antigens of breast cancer (Review)

Mariana Díaz-Zaragoza, Ricardo Hernández-Ávila, Rubí Viedma‑Rodríguez, Diego Arenas-Aranda, Pedro Ostoa-Saloma

Pages: 1106-1114 Published online on: 30 June 2015
Open Access

Effects of daidzein in regards to cytotoxicity in vitro, apoptosis, reactive oxygen species level, cell cycle arrest and the expression of caspase and Bcl-2 family proteins

Bing-Jie Han, Wei Li, Guang-Bin Jiang, Shang-Hai Lai, Cheng Zhang, Chuan-Chuan Zeng, Yun-Jun Liu

Pages: 1115-1120 Published online on: 14 July 2015
Open Access

Knockdown of SOX18 inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells

Guiming Wang, Zhigang Wei, Hongyan Jia, Wenbo Zhao, Gaochao Yang, Haoliang Zhao

Pages: 1121-1128 Published online on: 07 July 2015
Open Access

Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway

Xiaolong Yu, Xin Zhou, Changlin Fu, Qiang Wang, Tao Nie, Fan Zou, Runsheng Guo, Hucheng Liu, Bin Zhang, Min Dai

Pages: 1129-1136 Published online on: 13 July 2015
Open Access

Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer

Takashi Sato, Kenzo Soejima, Eri Arai, Junko Hamamoto, Hiroyuki Yasuda, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Katsuhiko Naoki, Takashi Kohno, Koji Tsuta, Shun-Ichi Watanabe, Yae Kanai, Tomoko Betsuyaku

Pages: 1137-1145 Published online on: 25 June 2015
Open Access

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance

Loredana Vesci, Valeria Carollo, Giuseppe Roscilli, Luigi Aurisicchio, Fabiana Fosca Ferrara, Luigi Spagnoli, Rita De Santis

Pages: 1146-1152 Published online on: 24 June 2015
Open Access

miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3

Hong Jiang, Wei-Wei Yu, Lu-Lu Wang, Yang Peng

Pages: 1153-1161 Published online on: 01 July 2015
Open Access

Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells

Yuhui Huang, Motofumi Kumazoe, Jaehoon Bae, Shuhei Yamada, Mika Takai, Shiori Hidaka, Shuya Yamashita, Yoonhee Kim, Yeongseon Won, Motoki Murata, Shuntaro Tsukamoto, Hirofumi Tachibana

Pages: 1162-1168 Published online on: 26 June 2015
Open Access

Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells

Teruya Nagahara, Hidenori Shiraha, Hiroaki Sawahara, Daisuke Uchida, Yasuto Takeuchi, Masaya Iwamuro, Junro Kataoka, Shigeru Horiguchi, Takeshi Kuwaki, Hideki Onishi, Shinichiro Nakamura, Akinobu Takaki, Kazuhiro Nouso, Kazuhide Yamamoto

Pages: 1169-1177 Published online on: 13 July 2015

Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling

Soojung Jin, Hee Jung Yun, Hyun Young Jeong, You Na Oh, Hyun‑Jin Park, Seung-Geun Yun, Byung Woo Kim, Hyun Ju Kwon

Pages: 1178-1184 Published online on: 24 June 2015

Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells

Naoki Makita, Itasu Ninomiya, Tomoya Tsukada, Koichi Okamoto, Shinichi Harada, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Katsunobu Oyama, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta

Pages: 1185-1192 Published online on: 26 June 2015

Activation of ARK5/miR-1181/HOXA10 axis promotes epithelial-mesenchymal transition in ovarian cancer

Hai-Yan Zhang, Jian-Hua Li, Guang Li, Su-Rong Wang

Pages: 1193-1202 Published online on: 07 July 2015

HOXA1 enhances the cell proliferation, invasion and metastasis of prostate cancer cells

Haitao Wang, Guanzhong Liu, Dan Shen, Huamao Ye, Jinming Huang, Li Jiao, Yinghao Sun

Pages: 1203-1210 Published online on: 26 June 2015

Expression of DNA ligase IV is linked to poor prognosis and characterizes a subset of prostate cancers harboring TMPRSS2:ERG fusion and PTEN deletion

Katharina Grupp, Laura Roettger, Martina Kluth, Claudia Hube-Magg, Ronald Simon, Patrick Lebok, Sarah Minner, Maria Christina Tsourlakis, Christina Koop, Markus Graefen, Meike Adam, Alexander Haese, Corinna Wittmer, Guido Sauter, Waldemar Wilczak, Hartwig Huland, Thorsten Schlomm, Stefan Steurer, Till Krech

Pages: 1211-1220 Published online on: 25 June 2015

Suppression of KLF8 induces cell differentiation and sensitizes colorectal cancer to 5-fluorouracil

Xinpeng Shi, Xiaoyong Luo, Qingqing Yan, Wenjing Zhang, Yao Wu, Mengnan Zhang, Jinjun Zhao, Ying Peng, Ye Chen, Yali Zhang, Cunlong Chen, Tianming Cheng, Chudi Chen, Side Liu, Yang Bai, Jide Wang

Pages: 1221-1230 Published online on: 30 June 2015

CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer

Tiing Jen Loh, Heegyum Moon, Sunghee Cho, Hana Jang, Yong Chao Liu, Hongmei Tai, Da-Woon Jung, Darren R. Williams, Hey-Ran Kim, Myung-Geun Shin, D. Joshua Liao, Jianhua Zhou, Wei Shi, Xuexiu Zheng, Haihong Shen

Pages: 1231-1238 Published online on: 06 July 2015

ZGDHu-1 and fludarabine have a synergistic effect on apoptosis of chronic lymphocytic leukemia cells

Liannv Qiu, Jinlin Liu, Zhenni Wang, Weixiao Hu, Qiang Huang, Yonglie Zhou

Pages: 1239-1248 Published online on: 08 July 2015

A secretomic study on human hepatocellular carcinoma multiple drug-resistant cell lines

Yi Xiang, Yi Liu, Yixuan Yang, Huaidong Hu, Peng Hu, Hong Ren, Dazhi Zhang

Pages: 1249-1260 Published online on: 03 July 2015

Ursodeoxycholic acid effectively kills drug-resistant gastric cancer cells through induction of autophagic death

Sung-Chul Lim, Song Iy Han

Pages: 1261-1268 Published online on: 24 June 2015

Circulating classical CD14++CD16- monocytes predict shorter time to initial treatment in chronic lymphocytic leukemia patients: Differential effects of immune chemotherapy on monocyte-related membrane and soluble forms of CD163

Izabela Lapuc, Lukasz Bolkun, Andrzej Eljaszewicz, Malgorzata Rusak, Ewa Luksza, Paulina Singh, Paula Miklasz, Jaroslaw Piszcz, Katarzyna Ptaszynska‑Kopczynska, Malgorzata Jasiewicz, Karol Kaminski, Milena Dabrowska, Anna Bodzenta-Lukaszyk, Janusz Kloczko, Marcin Moniuszko

Pages: 1269-1278 Published online on: 26 June 2015

RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling

Hong Zhu, Muyasha Abulimiti, Huan Liu, Xiang-Jiang Su, Cai-Hong Liu, Hai-Ping Pei

Pages: 1279-1288 Published online on: 25 June 2015

Identification of genes and long non-coding RNAs associated with the pathogenesis of gastric cancer

Zhiwei Zhao, Yan Song, Daxun Piao, Tianyou Liu, Liangliang Zhao

Pages: 1301-1310 Published online on: 14 July 2015

Antitumor activity of a 2-pyridinecarboxaldehyde 2-pyridinecarboxylic acid hydrazone copper complex and the related mechanism

Yingli Yang, Tengfei Huang, Sufeng Zhou, Yun Fu, Youxun Liu, Yanbin Yuan, Qiongqing Zhang, Shaoshan Li, Changzheng Li

Pages: 1311-1318 Published online on: 26 June 2015

Nuclear vasohibin-2 promotes cell proliferation by inducing G0/G1 to S phase progression

Qianqian Ge, Jia Zhou, Min Tu, Xiaofeng Xue, Zhanjun Li, Zipeng Lu, Jishu Wei, Guoxin Song, Jianmin Chen, Feng Guo, Kuirong Jiang, Yi Miao, Wentao Gao

Pages: 1327-1336 Published online on: 13 July 2015

Expression and activity analysis of a new fusion protein targeting ovarian cancer cells

Manman Su, Weiqin Chang, Dingding Wang, Manhua Cui, Yang Lin, Shuying Wu, Tianmin Xu

Pages: 1337-1344 Published online on: 09 July 2015

Binding of MMP-9-degraded fibronectin to β6 integrin promotes invasion via the FAK-Src-related Erk1/2 and PI3K/Akt/Smad-1/5/8 pathways in breast cancer

Wentong Li, Zhijun Liu, Chunling Zhao, Limin Zhai

Pages: 1345-1352 Published online on: 02 July 2015

The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma

Tianci Han, Zhiyong Wang, Yang Yang, Tianci Shu, Weinan Li, Dali Liu, Peiwen Li, Ruiqun Qi, Yi Ren, Li Li, Hong Liu, Shuguang Zhang, Lin Zhang

Pages: 1353-1360 Published online on: 26 June 2015

Concentration-dependent differential effects of an epothilone analog on cell cycle and p53 signaling

Fan An, Wei-Jie Zhao, Li Tang, Rong-Guo Qiu

Pages: 1361-1368 Published online on: 14 July 2015

GALC gene is downregulated by promoter hypermethylation in Epstein-Barr virus-associated nasopharyngeal carcinoma

Yinghai Zhao, Ying Guo, Zhijing Wang, Zebin Xiao, Rong Li, Aihua Luo, Changli Wu, Zhiliang Jing, Ning Sun, Xiaoyi Chen, Haijun Du, Yi Zeng

Pages: 1369-1378 Published online on: 14 July 2015

A limited overlap between intratumoral distribution of 1-(5-fluoro-5-deoxy-α-D-arabinofuranosyl)-2-nitroimidazole and copper-diacetyl-bis[N(4)-methylthiosemicarbazone]

Takako Furukawa, Qinghua Yuan, Zhao-Hui Jin, Winn Aung, Yukie Yoshii, Sumitaka Hasegawa, Hiroko Endo, Masahiro Inoue, Ming‑Rong Zhang, Yasuhisa Fujibayashi, Tsuneo Saga

Pages: 1379-1387 Published online on: 25 June 2015

Evodiamine inhibits the proliferation of human osteosarcoma cells by blocking PI3K/Akt signaling

Zi-Jun Meng, Nian Wu, Yang Liu, Ke-Jie Shu, Xiang Zou, Ran-Xi Zhang, Chang-Jun Pi, Bai-Cheng He, Zhen-Yong Ke, Liang Chen, Zhong-Liang Deng, Liang-Jun Yin

Pages: 1388-1396 Published online on: 25 June 2015

High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer

Miao Yun, Jian Rong, Zhi-Rui Lin, Yu-Long He, Jia-Xing Zhang, Zhen-Wei Peng, Lin-Quan Tang, Mu-Sheng Zeng, Qian Zhong, Sheng Ye

Pages: 1397-1405 Published online on: 30 June 2015

SPARC ectopic overexpression inhibits growth and promotes programmed cell death in acute myeloid leukemia transformed from myelodysplastic syndrome cells, alone and in combination with Ara-C treatment

Qing Nian, Jianxiang Chi, Qing Xiao, Chunmei Wei, Paul Costeas, Zesong Yang, Lin Liu, Li Wang

Pages: 1406-1414 Published online on: 08 July 2015

miR-99b promotes metastasis of hepatocellular carcinoma through inhibition of claudin 11 expression and may serve as a prognostic marker

Jianhui Yang, Xiwu Liu, Xiaohua Yuan, Zhiming Wang

Pages: 1415-1423 Published online on: 02 July 2015

PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway

Jinye Xu, Junbo Cai, Xiaoyan Jin, Jingjin Yang, Qinyan Shen, Xiaofei Ding, Yong Liang

Pages: 1424-1430 Published online on: 30 June 2015

Knockdown of zinc transporter ZIP5 (SLC39A5) expression significantly inhibits human esophageal cancer progression

Jing Jin, Zhongxin Li, Jianghui Liu, Yan Wu, Xing Gao, Yutong He

Pages: 1431-1439 Published online on: 01 July 2015

Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro

Xiaobai Wei, Jingcheng Dong

Pages: 1440-1448 Published online on: 03 July 2015

Topical treatment with Xiaozheng Zhitong Paste alleviates bone cancer pain by inhibiting proteinase-activated receptor 2 signaling pathway

Yanju Bao, Gaimei Wang, Yebo Gao, Maobo Du, Liping Yang, Xiangying Kong, Honggang Zheng, Wei Hou, Baojin Hua

Pages: 1449-1459 Published online on: 24 June 2015

REV3L modulates cisplatin sensitivity of non-small cell lung cancer H1299 cells

Wenjie Wang, Wenjiong Sheng, Chenxiao Yu, Jianping Cao, Jundong Zhou, Jinchang Wu, Huojun Zhang, Shuyu Zhang

Pages: 1460-1468 Published online on: 09 July 2015

Umbilical cord-derived mesenchymal stem cells promote proliferation and migration in MCF-7 and MDA-MB-231 breast cancer cells through activation of the ERK pathway

Tao Li, Chunfu Zhang, Yanling Ding, Wei Zhai, Kui Liu, Fan Bu, Tao Tu, Lingxian Sun, Wei Zhu, Fangfang Zhou, Wenkai Qi, Jiabo Hu, Huabiao Chen, Xiaochun Sun

Pages: 1469-1477 Published online on: 03 July 2015

Low-dose UVB irradiation prevents MMP2-induced skin hyperplasia by inhibiting inflammation and ROS

Lin Dang, Yan Wang, Yadong Xue, Lei He, Yuzhen Li, Jikui Xiong

Pages: 1478-1486 Published online on: 24 June 2015

Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria

Haiyang Jiang, Lei Zhao, Xiaoshen Dong, Anning He, Caiwei Zheng, Magnus Johansson, Anna Karlsson, Xinyu Zheng

Pages: 1487-1493 Published online on: 02 July 2015

STC2 overexpression mediated by HMGA2 is a biomarker for aggressiveness of high-grade serous ovarian cancer

Jingjing Wu, Maode Lai, Changshun Shao, Jian Wang, Jian-Jun Wei

Pages: 1494-1502 Published online on: 09 July 2015

Hypomethylated Rab27b is a progression-associated prognostic biomarker of glioma regulating MMP-9 to promote invasion

Hongjun Wang, Yongzhi Wang, Zhaoshi Bao, Chuanbao Zhang, Yanwei Liu, Jinquan Cai, Chuanlu Jiang

Pages: 1503-1509 Published online on: 13 July 2015

Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation

Weiyi Huang, Weiqing Zhong, Jun Xu, Benhua Su, Guanghui Huang, Jiajun Du, Qi Liu

Pages: 1510-1516 Published online on: 14 July 2015

Flavonoids isolated from Citrus platymamma induce mitochondrial-dependent apoptosis in AGS cells by modulation of the PI3K/AKT and MAPK pathways

Ho Jeong Lee, Arulkumar Nagappan, Hyeon Soo Park, Gyeong Eun Hong, Silvia Yumnam, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Won Sup Lee, Eun Hee Kim, Gon Sup Kim

Pages: 1517-1525 Published online on: 10 July 2015

Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells

Alan P. Lombard, Rebecca M. Lim, Rachel M. Nakagawa, Kathleen D. Vidallo, Stephen J. Libertini, Alexander J. Platero, Maria Mudryj

Pages: 1526-1532 Published online on: 09 July 2015

Antitumor effects of a drug combination targeting glycolysis, glutaminolysis and de novo synthesis of fatty acids

Diana Cervantes-Madrid, Alfonso Dueñas-González

Pages: 1533-1542 Published online on: 24 June 2015

ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells

Yan Ye, Xiao-Juan Chao, Jin-Feng Wu, Brian Chi-Yan Cheng, Tao Su, Xiu-Qiong Fu, Ting Li, Hui Guo, Anfernee Kai-Wing Tse, Hiu-Yee Kwan, Juan Du, Gui-Xin Chou, Zhi-Ling Yu

Pages: 1543-1548 Published online on: 06 July 2015

Roscovitine has anti-proliferative and pro-apoptotic effects on glioblastoma cell lines: A pilot study

M. Kolodziej, C. Goetz, P. Di Fazio, R. Montalbano, M. Ocker, H. Strik, K. Quint

Pages: 1549-1556 Published online on: 03 July 2015

MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy

Xiangliang Zhang, Huijuan Shi, Shengqv Lin, Mingchen Ba, Shuzhong Cui

Pages: 1557-1564 Published online on: 25 June 2015

Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells

Xiaohui Peng, Yan Zhou, Hua Tian, Gaoxiang Yang, Chunliu Li, Yang Geng, Sai Wu, Wei Wu

Pages: 1565-1572 Published online on: 01 July 2015

miR-133a inhibits cervical cancer growth by targeting EGFR

Xuesong Song, Bo Shi, Kexin Huang, Wenjie Zhang

Pages: 1573-1580 Published online on: 02 July 2015

ERK5 positively regulates cigarette smoke-induced urocystic epithelial-mesenchymal transition in SV‑40 immortalized human urothelial cells

Hao Geng, Li Zhao, Zhaofeng Liang, Zhiqiang Zhang, Dongdong Xie, Liangkuan Bi, Yi Wang, Tao Zhang, Lei Cheng, Dexin Yu, Caiyun Zhong

Pages: 1581-1588 Published online on: 14 July 2015

Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel

David W. Koh, Daniel P. Powell, Steven D. Blake, Joy L. Hoffman, Mandi M. Hopkins, Xiaoxing Feng

Pages: 1589-1598 Published online on: 14 July 2015

Suppression of casein kinase 2 sensitizes tumor cells to antitumor TRAIL therapy by regulating the phosphorylation and localization of p65 in prostate cancer

Xiaokun Gang, Yao Wang, Yingdi Wang, Yu Zhao, Liya Ding, Jingwen Zhao, Lin Sun, Guixia Wang

Pages: 1599-1604 Published online on: 13 July 2015

MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression

Sung Lyea Park, Tae-Min Cho, Se Yeon Won, Jun-Hui Song, Dae‑Hwa Noh, Wun-Jae Kim, Sung-Kwon Moon

Pages: 1605-1612 Published online on: 09 July 2015

Differential effect of EGFR inhibitors on tamoxifen-resistant breast cancer cells

Sangmin Kim, Jeongmin Lee, Soo Jin Oh, Seok Jin Nam, Jeong Eon Lee

Pages: 1613-1619 Published online on: 08 July 2015

Energy metabolism determines the sensitivity of human hepatocellular carcinoma cells to mitochondrial inhibitors and biguanide drugs

Chia-Chi Hsu, Ling-Chia Wu, Cheng-Yuan Hsia, Pen-Hui Yin, Chin‑Wen Chi, Tien-Shun Yeh, Hsin-Chen Lee

Pages: 1620-1628 Published online on: 30 June 2015
Journal Cover

September 2015
Volume 34 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2014 Impact Factor: 2.301
Ranked #31/211 Oncology
(total number of cites)

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