Journal Articles

The complex liaison between cachexia and tumor burden (Review)

Andrea De Lerma Barbaro

Pages: 1635-1649 Published online on: 31 July 2015
Open Access

NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells

Yoshihiro Hayashi, Makoto Osanai, Gang-Hong Lee

Pages: 1650-1658 Published online on: 04 August 2015
Open Access

Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product

Mamdooh Ghoneum, Nouran Felo

Pages: 1659-1666 Published online on: 06 August 2015
Open Access

Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder

Mariana Chantre-Justino, Gilda Alves, Constança Britto, Angélica Cardoso, Luciano Scherrer, Aline dos Santos Moreira, Raul Quirino, Antonio Ornellas, Alvaro Leitão, Claudia Lage

Pages: 1667-1674 Published online on: 24 July 2015
Open Access

Differential crosstalk between the AMPK and PI3K/Akt pathways in breast cancer cells of differing genotypes: Leptin inhibits the effectiveness of AMPK activation

Omar S. El-Masry, Kaltoom Al-Sakkaf, Barry L. Brown, Pauline R.M. Dobson

Pages: 1675-1680 Published online on: 11 August 2015
Open Access

HOXD10 acts as a tumor-suppressive factor via inhibition of the RHOC/AKT/MAPK pathway in human cholangiocellular carcinoma

Haixia Yang, Jiupeng Zhou, Jianqiang Mi, Ke Ma, Yangwei Fan, Jing Ning, Chuying Wang, Xin Wei, Huadong Zhao, Enxiao Li

Pages: 1681-1691 Published online on: 10 August 2015
Open Access

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity

Yee-Lin Voon, Munirah Ahmad, Pooi-Fong Wong, Roslina Husaini, Wayne Tiong-Weng Ng, Chee-Onn Leong, David Philip Lane, Alan Soo-Beng Khoo

Pages: 1692-1700 Published online on: 05 August 2015
Open Access

Acquirement of DNA copy number variations in non‑small cell lung cancer metastasis to the brain

Fang Li, Libo Sun, Sixun Zhang

Pages: 1701-1707 Published online on: 10 August 2015

The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth

Congren Wang, Xuejin Wang, Zijian Su, Hongjiang Fei, Xiaoyu Liu, Qunxiong Pan

Pages: 1708-1716 Published online on: 23 July 2015

Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer

Ana Ines Cases, Takao Ohtsuka, Hideyo Kimura, Biao Zheng, Koji Shindo, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura, Masao Tanaka

Pages: 1717-1725 Published online on: 20 July 2015

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species

Motoya Tanaka, Yuji Miura, Hiroki Numanami, Sivasundaram Karnan, Akinobu Ota, Hiroyuki Konishi, Yoshitaka Hosokawa, Masayuki Hanyuda

Pages: 1726-1732 Published online on: 27 July 2015

Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice

Jung Joo Rhyu, Jun-Won Yun, Euna Kwon, Jeong-Hwan Che, Byeong-Cheol Kang

Pages: 1733-1744 Published online on: 07 August 2015

Subpath analysis of each subtype of head and neck cancer based on the regulatory relationship between miRNAs and biological pathways

Fengwei An, Zhiqiang Zhang, Ming Xia, Lijun Xing

Pages: 1745-1754 Published online on: 24 July 2015

12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway

Ying Yang, Huan Cong, Cuicui Han, Liling Yue, Haiying Dong, Jicheng Liu

Pages: 1755-1760 Published online on: 31 July 2015

Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest

Kiyoyuki Kobayashi, Asahiro Morishita, Hisakazu Iwama, Koji Fujita, Ryoichi Okura, Shintaro Fujihara, Takuma Yamashita, Takayuki Fujimori, Kiyohito Kato, Hideki Kamada, Toshiro Niki, Mitsuomi Hirashima, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki

Pages: 1761-1770 Published online on: 10 August 2015

microRNA-22 downregulation of galectin-9 influences lymphocyte apoptosis and tumor cell proliferation in liver cancer

Qianqian Yang, Weichao Jiang, Chunbo Zhuang, Zhi Geng, Chen Hou, Da Huang, Lihua Hu, Xiaobei Wang

Pages: 1771-1778 Published online on: 31 July 2015

Expression profile analysis of microRNAs and downregulated miR-486-5p and miR-30a-5p in non-small cell lung cancer

Jianjie Zhu, Yuanyuan Zeng, Chun Xu, Hualong Qin, Zhe Lei, Dan Shen, Zeyi Liu, Jian-An Huang

Pages: 1779-1786 Published online on: 21 July 2015

Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway

Qiong Fan, Mei-Ting Qiu, Zhu Zhu, Jin-Hua Zhou, Limo Chen, Ye Zhou, Wei Gu, Li‑Hua Wang, Zhu-Nan Li, Ying Xu, Wei-Wei Cheng, Dan Wu, Wei Bao

Pages: 1787-1794 Published online on: 22 July 2015

Enhanced therapeutic effects against murine colon carcinoma induced by a Colon 26/Ag85A-CD226 tumor cell vaccine

Yan Li, Fangli Yang, Lixuan Sang, Junfeng Zhu, Xue Han, Fengping Shan, Shengjun Li, Jingbo Zhai, Danan Wang, Changlong Lu, Xun Sun

Pages: 1795-1804 Published online on: 20 July 2015

Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo

Yang‑Yang Bao, Shui‑Hong Zhou, Zhong‑Jie Lu, Jun Fan, Ya‑Ping Huang

Pages: 1805-1814 Published online on: 28 July 2015

Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells

Leilei Wang, Kai Zhao, Bingcheng Ren, Meng Zhu, Chen Zhang, Pengfei Zhao, Hua Zhou, Lei Chen, Shenping Yu, Xuejun Yang

Pages: 1815-1824 Published online on: 28 July 2015

Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer

Jie Ding, Min Feng, Feng Wang, Hao Wang, Wenxian Guan

Pages: 1825-1834 Published online on: 22 July 2015

Effect of Rab23 on the proliferation and apoptosis in breast cancer

Yali Liu, Chao Zeng, Nandi Bao, Jie Zhao, Yuzhen Hu, Chengxin Li, Sumin Chi

Pages: 1835-1844 Published online on: 24 July 2015

MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation, migration and invasion of breast cancer cells

Lei Yu, Yanming Yang, Jiguang Hou, Chengwei Zhai, Yunhao Song, Zhiliang Zhang, Ling Qiu, Xiaojing Jia

Pages: 1845-1852 Published online on: 05 August 2015

Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro

I-Tsang Chiang, Wei-Shu Wang, Hsin-Chung Liu, Su-Tso Yang, Nou-Ying Tang, Jing-Gung Chung

Pages: 1853-1874 Published online on: 29 July 2015

Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3

Haishi Qiao, Dan Zhao, Hengfei Shi, Ke Ren, Jianxin Li, Erguang Li

Pages: 1875-1882 Published online on: 21 July 2015

RRM1, TUBB3, TOP2A, CYP19A1, CYP2D6: Difference between mRNA and protein expression in predicting prognosis of breast cancer patients

Ying-Chun Xu, Feng-Chun Zhang, Jun-Jian Li, Jia-Qi Dai, Qiang Liu, Lei Tang, Yue Ma, Qi Xu, Xiao-Lin Lin, Hong-Bin Fan, Hong-Xia Wang

Pages: 1883-1894 Published online on: 07 August 2015

Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells

Xue Zou, Mengxiao Zhang, Yiming Sun, Surong Zhao, Yingmei Wei, Xudong Zhang, Chenchen Jiang, Hao Liu

Pages: 1895-1904 Published online on: 23 July 2015

Never in mitosis gene A-related kinase 6 and aurora kinase A: New gene biomarkers in the conversion from ulcerative colitis to colorectal cancer

Emre Gerçeker, Seda Orenay Boyacıoglu, Elmas Kasap, Ahmed Baykan, Hakan Yuceyar, Hatice Yıldırım, Semin Ayhan, Ender Ellidokuz, Mehmet Korkmaz

Pages: 1905-1914 Published online on: 10 August 2015

Bone marrow-derived mesenchymal stem cells co‑expressing interleukin-18 and interferon-β exhibit potent antitumor effect against intracranial glioma in rats

Gang Xu, Yanwu Guo, Zhiyuan Seng, Gang Cui, Jianqiang Qu

Pages: 1915-1922 Published online on: 05 August 2015

miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4

Ji Cheng, Rui Deng, Peng Zhang, Chuanqing Wu, Ke Wu, Liang Shi, Xinghua Liu, Jie Bai, Meizhou Deng, Xiaoming Shuai, Jinbo Gao, Guobin Wang, Kaixiong Tao

Pages: 1923-1932 Published online on: 04 August 2015

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells

Parunya Chaiyawat, Daranee Chokchaichamnankit, Kriengsak Lirdprapamongkol, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

Pages: 1933-1942 Published online on: 05 August 2015

MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1α in nasopharyngeal carcinoma

Ying Shan, Xingyu Li, Bo You, Si Shi, Qicheng Zhang, Yiwen You

Pages: 1943-1952 Published online on: 10 August 2015

Targeted delivery of doxorubicin to breast cancer cells by aptamer functionalized DOTAP/DOPE liposomes

Xingli Song, Yi Ren, Jing Zhang, Gang Wang, Xuedong Han, Wei Zheng, Linlin Zhen

Pages: 1953-1960 Published online on: 17 July 2015

Prediction of response to preoperative chemoradiotherapy and establishment of individualized therapy in advanced rectal cancer

Toshihiro Nakao, Takashi Iwata, Masanori Hotchi, Kozo Yoshikawa, Jun Higashijima, Masaaki Nishi, Chie Takasu, Shohei Eto, Hiroki Teraoku, Mitsuo Shimada

Pages: 1961-1967 Published online on: 10 August 2015

Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation

Wilhelmina C.M. Duivenvoorden, Sarah N. Hopmans, Daniel Gallino, Thomas Farrell, Carrie Gerdes, Diana Glennie, Himu Lukka, Jehonathan H. Pinthus

Pages: 1968-1976 Published online on: 07 August 2015

Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications

Xiang Y. Gao, Lin Li, Xiao H. Wang, Xian Z. Wen, Ke Ji, Lin Ye, Jun Cai, Wen G. Jiang, Jia F. Ji

Pages: 1977-1987 Published online on: 30 July 2015

MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression

Yue Wang, Hua Xin, Zhifeng Han, Hongbing Sun, Nan Gao, Haixiang Yu

Pages: 1988-1994 Published online on: 07 August 2015

Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Masashi Miyazaki, Shinichi Ikeda, Hiroshi Tsumura

Pages: 1995-2001 Published online on: 29 July 2015

NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways

Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi, Guowei Zuo

Pages: 2011-2021 Published online on: 24 July 2015

Fusion of cancer stem cells and mesenchymal stem cells contributes to glioma neovascularization

Chao Sun, Dongliang Zhao, Xingliang Dai, Jinsheng Chen, Xiaoci Rong, Haiyang Wang, Aidong Wang, Ming Li, Jun Dong, Qiang Huang, Qing Lan

Pages: 2022-2030 Published online on: 16 July 2015

Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host disease

Xiaocui Li, Cuiping Zhang, Wei Chen, Bin Pan, Fanyun Kong, Kuiyang Zheng, Renxian Tang, Lingyu Zeng

Pages: 2031-2039 Published online on: 05 August 2015

Aqueous extract of Psoralea corylifolia L. inhibits lipopolysaccharide-induced endothelial-mesenchymal transition via downregulation of the NF-κB-SNAIL signaling pathway

Bom Jung, Eun Hyang Jang, Darong Hong, In Hye Cho, Min-Ju Park, Jong-Ho Kim

Pages: 2040-2046 Published online on: 27 July 2015

Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models

Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun‑Joo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang

Pages: 2047-2053 Published online on: 10 August 2015

MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma

Qiuran Xu, Meiqi Zhang, Jianfeng Tu, Linxiao Pang, Wenwei Cai, Xin Liu

Pages: 2054-2064 Published online on: 05 August 2015

Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells

Sang Hyuk Lee, Hyo Jung Nam, Hyun Jung Kang, Tina L. Samuels, Nikki Johnston, Young Chang Lim

Pages: 2065-2071 Published online on: 23 July 2015

Gene expression profiling in myelodysplastic syndrome after SPARC overexpression associated with Ara-C

Qing Nian, Zhiqiang Zhang, Chunmei Wei, Xingyi Kuang, Xingyong Wang, Li Wang

Pages: 2072-2082 Published online on: 20 July 2015

MG132 enhances the radiosensitivity of lung cancer cells in vitro and in vivo

Wei Zhu, Jing Liu, Jihua Nie, Wenjiong Sheng, Han Cao, Wenhao Shen, Aijing Dong, Jundong Zhou, Yang Jiao, Shuyu Zhang, Jianping Cao

Pages: 2083-2089 Published online on: 04 August 2015

Hepatitis B virus X protein modifies invasion, proliferation and the inflammatory response in an HTR-8/SVneo cell model

Hong Cui, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu

Pages: 2090-2098 Published online on: 05 August 2015

Expression of immune checkpoint molecules of T cell immunoglobulin and mucin protein 3/galectin-9 for NK cell suppression in human gastrointestinal stromal tumors

Hideo Komita, Shigeo Koido, Kazumi Hayashi, Shin Kan, Masaki Ito, Yuko Kamata, Masafumi Suzuki, Sadamu Homma

Pages: 2099-2105 Published online on: 24 July 2015

Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer

Yun Wang, Ling-Yun Wang, Fen Feng, Yang Zhao, Ma-Yan Huang, Qiong Shao, Cui Chen, Hui Sheng, Dong-Liang Chen, Zhao-Lei Zeng, Rui-Hua Xu, Yu-Hong Li

Pages: 2106-2114 Published online on: 28 July 2015

Effect of DR4 promoter methylation on the TRAIL‑induced apoptosis in lung squamous carcinoma cell

Wenwu Wang, Xiaoyan Qi, Minghua Wu

Pages: 2115-2125 Published online on: 04 August 2015

Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line

Changhong Zhao, Sarra Setrerrahmane, Hanmei Xu

Pages: 2126-2132 Published online on: 30 July 2015

Simvastatin protects Sertoli cells against cisplatin cytotoxicity through enhanced gap junction intercellular communication

Lingzhi Wang, Jianxin Peng, Huansen Huang, Qin Wang, Meiling Yu, Liang Tao

Pages: 2133-2141 Published online on: 10 August 2015

Meloxicam combined with sorafenib synergistically inhibits tumor growth of human hepatocellular carcinoma cells via ER stress-related apoptosis

Jingtao Zhong, Peng Xiu, Xiaofeng Dong, Fuhai Wang, Honglong Wei, Xin Wang, Zongzhen Xu, Feng Liu, Tao Li, Yong Wang, Jie Li

Pages: 2142-2150 Published online on: 06 August 2015

A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility

Shi Yan, Cunzhong Yuan, Qifeng Yang, Xiaoyan Li, Ning Yang, Xiaoyan Liu, Ruihua Dong, Xi Zhang, Zeng Yuan, Ning Zhang, Beihua Kong

Pages: 2151-2155 Published online on: 05 August 2015

MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression

Haige Zhang, Qingxia Fan

Pages: 2163-2170 Published online on: 23 July 2015

miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1

Ran Xu, Guang Zeng, Jing Gao, Yue Ren, Zhe Zhang, Qingna Zhang, Jinxiu Zhao, Hong Tao, Daxu Li

Pages: 2171-2178 Published online on: 23 July 2015

HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation

Sung Ae Koh, Kyung Hee Lee

Pages: 2179-2187 Published online on: 10 August 2015

miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression

Xin Deng, Yi Zhao, Baosheng Wang

Pages: 2188-2194 Published online on: 29 July 2015

MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling

Can Zhang, Yihe Hu, Jun Wan, Hongbo He

Pages: 2195-2201 Published online on: 10 August 2015

miR-126 inhibits papillary thyroid carcinoma growth by targeting LRP6

Qiang Wen, Jie Zhao, Lin Bai, Tongtong Wang, Haishan Zhang, Qingjie Ma

Pages: 2202-2210 Published online on: 31 July 2015
Journal Cover

October 2015
Volume 34 Issue 4

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2014 Impact Factor: 2.301
Ranked #31/211 Oncology
(total number of cites)

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