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CYTOGENETICAL AND FISH ANALYSIS ON A SALIVARY SEBACEOUS LYMPHADENOMA

Authors:
J MARK, R DAHLENFORS, B WEDELL, G STENMAN, P BOCKMAN

Affiliations:
CENT HOSP SKOVDE,DEPT OTORHINOLARYNGOL,S-54185 SKOVDE,SWEDEN. GOTHENBURG UNIV,INST PATHOL,S-41390 GOTHENBURG,SWEDEN.

Pages:
561-562

Abstract:

Chromosomal studies of a cultured parotid sebaceous lymphadenoma showed two abnormal cell groups, one with trisomy 9 (15% of the metaphases) and one with inconsistent structural deviations (10%). FISH analysis showed that the trisomic clone was actually larger (36%) than that revealed by chromosomal studies. The sebaceous lymphadenoma represents the fourth type of benign salivary gland tumor to show clonal chromosomal deviations.

Oncology Reports

May 1994
Volume 1 Number 3


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