|CYTOGENETICAL AND FISH ANALYSIS ON A SALIVARY SEBACEOUS LYMPHADENOMA|
Authors: J MARK, R DAHLENFORS, B WEDELL, G STENMAN, P BOCKMAN
Affiliations: CENT HOSP SKOVDE,DEPT OTORHINOLARYNGOL,S-54185 SKOVDE,SWEDEN. GOTHENBURG UNIV,INST PATHOL,S-41390 GOTHENBURG,SWEDEN.
Chromosomal studies of a cultured parotid sebaceous lymphadenoma showed two abnormal cell groups, one with trisomy 9 (15% of the metaphases) and one with inconsistent structural deviations (10%). FISH analysis showed that the trisomic clone was actually larger (36%) than that revealed by chromosomal studies. The sebaceous lymphadenoma represents the fourth type of benign salivary gland tumor to show clonal chromosomal deviations.