|Angiogenesis in breast cancer: How should we measure this? (Review)|
Authors: M. J.K. Pollitt, A.M. Hanby, K. Horgan, C.E. Murphy, P.F. Jones, V. Speirs
Molecular Medicine Unit, University of Leeds, Clinical Sciences Building, St James's University Hospital, Leeds LS9 7TF, UK
Despite the established importance of angiogenesis in the pathogenesis of solid tumours, there is still no consensus on how this is best measured or which method is the most appropriate in the determination of prognosis. Here we review the pros and cons of current methods of assessing angiogenesis, both clinical and in the laboratory, and discuss with respect to breast cancer.