|Membrane fluidity correlates with liver cancer cell proliferation and infiltration potential|
Authors: N. O. Funaki, J. Tanaka, M. Kohmoto, T. Sugiyama, G. Ohshio, A. Nonaka, F. Yotsumoto, Y. Takeda, M. Imamura
Department of Surgery, Shiga Medical Center for Adults, Moriyama City, Shiga 524, Japan
We developed a method to measure membrane fluidity of living cancer cells in two- and three-dimensional cultures, and found that there was a close relationship between the membrane fluidity of cancer cells and their proliferative and infiltrative ability. Membrane fluidity is thus a promising indicator of the probability of cancer recurrence.