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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2004 Volume 12 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Ectopic expression of DICE1 suppresses tumor cell growth

Ilse Wieland, Christian Sell, Ulrich H. Weidle, P. Wieacker
Pages: 207-211
Published online on: 01 August 2004

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Article

Histopathology of ventricles, coronary arteries and mast cell accumulation in transverse and longitudinal sections of the rat heart after irradiation

M. Boerma, C. Zurcher, I. Esveldt, C. I. Schutte-Bart, J. Wondergem
Pages: 213-219
Published online on: 01 August 2004

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Article

Melanoma metastasis is associated with enhanced expression of the syntenin gene

Burkhard M. Helmke, Myriam Polychronidis, Axel Benner, Marianne Thome, Joaquín Arribas, Martin Deichmann
Pages: 221-228
Published online on: 01 August 2004

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Article

Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck

Nam-Yong Do, Sung-Chul Lim, Tae-Seung Im
Pages: 229-237
Published online on: 01 August 2004

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Article

Thymosin β-10 gene expression as a possible tool in diagnosis of thyroid neoplasias

Gennaro Chiappetta, Francesca Pentimalli, Mario Monaco, Monica Fedele, Rosa Pasquinelli, Giovanna Maria Pierantoni, Maria Teresa Ribecco, Giovanni Santelli, Daniela Califano, Luciano Pezzullo, Alfredo Fusco
Pages: 239-243
Published online on: 01 August 2004

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Article

Nuclear β-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers

Shin'ichi Miyamoto, Yasushi Endoh, Takahiro Hasebe, Genichiro Ishii, Keiji Kodama, Masato Goya, Masato Ono, Norio Saitoh, Tsutomu Chiba, Atsushi Ochiai
Pages: 245-251
Published online on: 01 August 2004

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Article

Cisplatin enhances the p53-independent apoptosis induced by a topoisomerase I inhibitor (CPT-11) in the lens epithelial tumors in transgenic mice

Takafumi Nakamura, Yasuo Nakajima, Takayuki Enomoto, Shinichi Hori, Takao Hidaka, Yuji Murata, Shigeru Saito
Pages: 253-258
Published online on: 01 August 2004

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Article

Expression of RCAS1 and its function in human squamous cell carcinoma of the oral cavity

Masakatsu Fukuda, Akio Tanaka, Aya Hamao, Seiji Suzuki, Kaoru Kusama, Hideaki Sakashita
Pages: 259-267
Published online on: 01 August 2004

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Article

Measurement of des-gamma-carboxy prothrombin levels in cancer and non-cancer tissue in patients with hepatocellular carcinoma

Lian-Wen Yuan, Wei Tang, Norihiro Kokudo, Yasuhiko Sugawara, Hirona Karako, Kiyoshi Hasegawa, Taku Aoki, Yusuke Kyoden, Geertu Deli, Yong-Guo Li, Masatoshi Makuuchi
Pages: 269-273
Published online on: 01 August 2004

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Article

Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers

Daisuke Yuki, Yu-Min Lin, Yoshitaka Fujii, Yusuke Nakamura, Yoichi Furukawa
Pages: 275-280
Published online on: 01 August 2004

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Article

DFU, a selective COX-2 inhibitor, suppresses MCF-7 xenograft tumor growth in mice

Gaku Matsumoto, Mohammad Atiqur Rahman, Mariko Muta, Tadahiko Nakamura, Hiroko Bando, Shigehira Saji, Koji Tsuruta, Atsutake Okamoto, Masakazu Toi
Pages: 281-285
Published online on: 01 August 2004

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Article

Dysregulation of apoptosis is a major mechanism in the lymph node involvement in colorectal carcinoma

Eva Bandres, Victoria Catalan, Iosu Sola, Beatriz Honorato, Elena Cubedo, Lucia Cordeu, Esther Andion, Alvaro Escalada, Ruth Zarate, Esteban Salgado, Natalia Zabalegui, Fermin García, Jesus Garcia-Foncillas
Pages: 287-292
Published online on: 01 August 2004

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Article

Constitutive activation of Stat3 correlates with increased expression of the c-Met/HGF receptor in oral squamous cell carcinoma

Sebastian Krystian Klosek, Koh-Ichi Nakashiro, Shingo Hara, Chunnan Li, Satoru Shintani, Hiroyuki Hamakawa
Pages: 293-296
Published online on: 01 August 2004

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Article

Comparative analysis of α2,3/2,6-linked N-acetylneuraminic acid and cytokeratin expression in head and neck squamous cell carcinoma

Martin Chovanec, Jan Plzák, Jan Betka, Jirí Brabec, Roman Kodet, Karel Smetana
Pages: 297-301
Published online on: 01 August 2004

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Article

Predicting the recurrence/metastasis of stage II and III breast cancer with lymph node metastasis

Masaya Mukai, Shinkichi Sato, Tomomi Kimura, Nobukazu Komatsu, Hiromi Ninomiya, Hisao Nakasaki, Kyouji Ogoshi, Hiroyasu Makuuchi
Pages: 303-306
Published online on: 01 August 2004

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Article

Usefulness of collagen gel droplet embedded culture drug sensitivity testing in ovarian cancer

Hiromitsu Yabushita, Masafumi Ohnishi, Megumi Komiyama, Takeshi Mori, Mari Noguchi, Tameko Kishida, Yasuyuki Noguchi, Keizo Sawaguchi, Masayoshi Noguchi
Pages: 307-311
Published online on: 01 August 2004

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Article

BRCA2 germline mutations in primary cancer of the fallopian tube

Sara Casarsa, Fabio Puglisi, Francesco Baudi, Loredana De Paola, Salvatore Venuta, Andrea Piga, Carla Di Loreto, Diego Marchesoni, Angela Valentina D'Elia, Giuseppe Damante
Pages: 313-316
Published online on: 01 August 2004

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Article

Establishment of a new scirrhous gastric carcinoma cell line with microsatellite instability

Tsuyoshi Koyama, Masakazu Yashiro, Tasuku Matsuoka, Takeshi Sunami, Masaichi Ohira, Kosei Hirakawa
Pages: 317-321
Published online on: 01 August 2004

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Article

Mobilization of peripheral blood stem cells (PBSCs) after etoposide, adriamycin and cisplatin therapy, and a multimodal cell therapy approach with PBSCs in advanced gastric cancer

Yuji Ueda, Yoshiaki Sonoda, Hiroshi Fujiki, Sachio Harada, Takafumi Kimura, Tsuyoshi Itoh, Kenichiro Imura, Kei Naito, Kenichi Nomura, Masafumi Taniwaki, Hisakazu Yamagishi
Pages: 323-332
Published online on: 01 August 2004

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Article

Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma

Hideyuki Shima, Toru Hiyama, Shinji Tanaka, Masanori Ito, Yasuhiko Kitadai, Masaharu Yoshihara, Koji Arihiro, Ken Haruma, Kazuaki Chayama
Pages: 333-337
Published online on: 01 August 2004

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Article

Influence of CpG island methylation status in O6-methylguanine-DNA methyltransferase expression of oral cancer cell lines

Jun Murakami, Jun-Ichi Asaumi, Yuu Maki, Hidetsugu Tsujigiwa, Hitoshi Nagatsuka, Susumu Kokeguchi, Tetsuyoshi Inoue, Shoji Kawasaki, Noriaki Tanaka, Donald MacPhee, Nagahide Matsubara, Kanji Kishi
Pages: 339-345
Published online on: 01 August 2004

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Article

Thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in hepatocellular carcinoma and metastatic liver cancer

Tsukasa Hotta, Yasuhito Kobayashi, Katsutoshi Taniguchi, Kiyofumi Johata, Masaki Sahara, Takashi Watanabe, Minoru Ochiai, Hiroshi Tanimura, Yukari T. Tsubota
Pages: 347-351
Published online on: 01 August 2004

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Article

Phosphatidylcholine and cholesteryl esters identify the infiltrating behaviour of a clear cell renal carcinoma: 1H, 13C and 31P MRS evidence

V. Tugnoli, A. Poerio, M. R. Tosi
Pages: 353-356
Published online on: 01 August 2004

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Article

p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel

Nobuhisa Matsuhashi, Masanao Saio, Atsushi Matsuo, Yasuyuki Sugiyama, Shigetoyo Saji
Pages: 357-361
Published online on: 01 August 2004

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Article

The analysis of pyridylamino-dextran sulfate oligomers by high-performance liquid chromatography and a novel detection system for sulfated polysaccharides

Yoshio Araki, Takuji Katoh, Mitsuyo Urabe, Yuuki Kishi, Izumi Ishizuka, Yoshihide Fujiyama
Pages: 363-367
Published online on: 01 August 2004

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Article

Effect of extracorporal high hydrostatic pressure on tumor cell adherence and viability

Peter Diehl, Ute Reuning, Hans Gollwitzer, Ulla Magdolen, Ludger Gerdesmeyer, Johannes Schauwecker, Jutta Tuebel, Reiner Gradinger, Wolfram Mittelmeier, Manfred Schmitt
Pages: 369-373
Published online on: 01 August 2004

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Article

Eradication of HPV post-surgical treatments, its correlation with specific types, types of surgery and the physical status

Jin Fen, Mitsuo Yoshinouchi, Keiichiro Nakamura, Junichi Kodama, Yasutomo Nasu, Kenji Yamato, Yuji Hiramatsu
Pages: 375-379
Published online on: 01 August 2004

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Article

High expression of two genes selected by iAFLP: A new prognostic factor of estrogen receptor-positive breast cancer

Noriko Aritake, Yasuhiro Tamaki, Norikazu Masuda, Yoshiaki Nakano, Takushi Monden, Shinzaburo Noguchi, Morito Monden
Pages: 381-387
Published online on: 01 August 2004

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Article

Hypermethylation of E-cadherin gene is frequent and independent of p16INK4A methylation in non-small cell lung cancer: Potential prognostic implication

Takashi Shimamoto, Junko H. Ohyashiki, Takashi Hirano, Harubumi Kato, Kazuma Ohyashiki
Pages: 389-395
Published online on: 01 August 2004

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Article

Confocal endomicroscopic imaging of normal and neoplastic human tongue tissue using ALA-induced-PPIX fluorescence: A preliminary study

Wei Zheng, Martin Harris, Kiang Wei Kho, Patricia S.P. Thong, Alan Hibbs, Malini Olivo, Khee Chee Soo
Pages: 397-401
Published online on: 01 August 2004

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Article

Overexpression of cyclooxygenase-2 in childhood ependymomas: Role of COX-2 inhibitor in growth and multi-drug resistance in vitro

Seung-Ki Kim, Su-Young Lim, Kyu-Chang Wang, Young-Yim Kim, Je G. Chi, Yoon La Choi, Hyung Jin Shin, Byung-Kyu Cho
Pages: 403-409
Published online on: 01 August 2004

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Article

Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine®)-induced cytotoxicity and apoptotic cell death in human breast cancer cells

Javier A. Menendez, Ramon Colomer, Ruth Lupu
Pages: 411-422
Published online on: 01 August 2004

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Article

Identification and characterization of human CKTSF1B2 and CKTSF1B3 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 423-427
Published online on: 01 August 2004

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Article

Identification and characterization of human TMEM25 and mouse Tmem25 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 429-433
Published online on: 01 August 2004

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Article

CD80 transfected human hepatocellular carcinoma cells activate cytotoxic T lymphocytes to target HCC cells with shared tumor antigens

Ray Chun-Fai Chan, Yong Xie
Pages: 435-442
Published online on: 01 August 2004

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Article

Adenovirus-mediated HSV-TK gene therapy using the human telomerase promoter induced apoptosis of small cell lung cancer cell line

Joon-Seok Song, Hyun-Pyo Kim
Pages: 443-447
Published online on: 01 August 2004

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Article

Nivalenol, a main Fusarium toxin in dietary foods from high-risk areas of cancer of esophagus and gastric cardia in China, induced benign and malignant tumors in mice

Chu Chieh Hsia, Ze Yuan Wu, Yun Sian Li, Fan Zhang, Zong Tang Sun
Pages: 449-456
Published online on: 01 August 2004

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Article

UGT1A1*28 polymorphism in ovarian cancer patients

Erika Cecchin, Antonio Russo, Giuseppe Corona, Elio Campagnutta, Luca Martella, Mauro Boiocchi, Giuseppe Toffoli
Pages: 457-462
Published online on: 01 August 2004

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Article

Mitochondrial DNA mutations in chemical carcinogen-induced rat bladder and human bladder cancer

Guang Fu Chen, Franky L. Chan, Bao Fa Hong, L. W. Chan, Peter S.F. Chan
Pages: 463-472
Published online on: 01 August 2004

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Article

Pegulated liposomal doxorubicin and cisplatin given concurrently with conventional radiotherapy: A phase I dose-escalation trial for patients with squamous cell carcinoma of head and neck and lung

H. Varveris, S. Kachris, M. Mazonakis, E. Lyraraki, A. Markouizou, S. Karabekios, A. Tzedakis, K. Perisinakis, J. Damilakis, M. Vlachaki
Pages: 473-481
Published online on: 01 August 2004

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Article

The localisation and reduction of nuclear staining of PPARγ and PGC-1 in human breast cancer

Gareth Watkins, Anthony Douglas-Jones, Robert E. Mansel, Wen G. Jiang
Pages: 483-488
Published online on: 01 August 2004

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

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Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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