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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2009 Volume 21 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Fluorescence diagnosis and flat lesions of urothelium: New challenges for pathologists and urologists (Review)

Eva Compérat, Pierre Conort, Morgan Roupret, Fréderique Capron, Philippe Camparo, Rodolfo Montironi
Pages: 839-844
Published online on: 01 April 2009

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Review

Breast cancer as a mitochondrial disorder (Review)

Katarzyna Plak, Anna M. Czarnecka, Tomasz Krawczyk, Pawel Golik, Ewa Bartnik
Pages: 845-851
Published online on: 01 April 2009

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Article

Expression of the prolyl isomerase Pin1 is a useful indicator of sensitivity to chemoradiotherapy in advanced esophageal squamous cell carcinoma

Minoru Fukuchi, Yasuyuki Fukai, Makoto Sohda, Tatsuya Miyazaki, Masanobu Nakajima, Takanori Inose, Naritaka Tanaka, Katsuhiko Tsukada, Hiroyuki Kato, Hiroyuki Kuwano
Pages: 853-859
Published online on: 01 April 2009

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Article

A study on the mechanism of 5-aminolevulinic acid photodynamic therapy in vitro and in vivo in cervical cancer

Gui-Fang He, Mei-Lu Bian, Ya-Wei Zhao, Qing Xiang, Hong-Yan Li, Cheng Xiao
Pages: 861-868
Published online on: 01 April 2009

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Article

Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line

Emi Segawa, Susumu Hashitani, Yukiyo Toyohara, Hiromitsu Kishimoto, Kazuma Noguchi, Kazuki Takaoka, Masahiro Urade
Pages: 869-874
Published online on: 01 April 2009

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Article

Co-expression of keratinocyte growth factor and K-sam is an independent prognostic factor in gastric carcinoma

Takahiro Toyokawa, Masakazu Yashiro, Kosei Hirakawa
Pages: 875-880
Published online on: 01 April 2009

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Article

A preoperative evaluation for neo-infantile liver tumors using a three-dimensional reconstruction of multidetector row CT

Yoshiaki Kinoshita, Ryota Souzaki, Tatsuro Tajiri, Satoshi Ieiri, Makoto Hashizume, Tomoaki Taguchi
Pages: 881-886
Published online on: 01 April 2009

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Case Report

Malignant melanoma with a rhabdoid phenotype exhibiting numerous solid tumor masses: A case report

Tomoki Nakamura, Akihiko Matsumine, Hiroaki Kato, Katsuyuki Kusuzaki, Keisuke Nishimura, Tetsuya Murata, Taizo Shiraishi, Yoshinao Oda, Masazumi Tsuneyoshi, Atsumasa Uchida
Pages: 887-891
Published online on: 01 April 2009

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Article

Estrogen and progestin regulate HIF-1α expression in ovarian cancer cell lines via the activation of Akt signaling transduction pathway

Keqin Hua, Jingxin Din, Qi Cao, Weiwei Feng, Ying Zhang, Liangqin Yao, Yan Huang, Yuqin Zhao, Youji Feng
Pages: 893-898
Published online on: 01 April 2009

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Case Report

A gastrointestinal stromal tumor presenting as a pelvic mass: A case report

Roberto Angioli, Cleonice Battista, Ludovico Muzii, Giovanna Madonna Terracina, Ester Valentina Cafà, Maria Isabella Sereni, Roberto Montera, Francesco Plotti, Carla Rabitti, Pierluigi Benedetti Panici
Pages: 899-902
Published online on: 01 April 2009

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Article

Differential expression of osteocalcin during the metastatic progression of prostate cancer

Thomas A. Gardner, Sang-Jin Lee, Sang-Don Lee, Xiong Li, Toshihiro Shirakawa, Dong Deuk Kwon, Ra Young Park, Kyu Youn Ahn, Chaeyong Jung
Pages: 903-908
Published online on: 01 April 2009

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Article

Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo

Min Yu, Junli Gong, Mingxing Ma, Hui Yang, Jianhua Lai, Hong Wu, Lin Li, Lamei Li, Deyong Tan
Pages: 909-915
Published online on: 01 April 2009

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Article

Influence of microenvironments on microcirculation patterns and tumor invasion-related protein expression in melanoma

Luxia Chen, Baocun Sun, Shiwu Zhang, Xiulan Zhao, Yanjin He, Shaozhen Zhao, Tingting Lin, Xiaorong Li
Pages: 917-923
Published online on: 01 April 2009

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Article

Overexpression of the LKB1 gene inhibits lung carcinoma cell proliferation partly through degradation of c-myc protein

Xuan Liang, Ke-Jun Nan, Zhao-Lun Li, Qing-Zhi Xu
Pages: 925-931
Published online on: 01 April 2009

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Article

Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels

Caren Jayasinghe, Nektaria Simiantonaki, Romi Michel-Schmidt, Charles James Kirkpatrick
Pages: 933-939
Published online on: 01 April 2009

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Article

Hepatitis B virus DNA-induced carcinogenesis of human normal liver cells by virtue of nonmethylated CpG DNA

Xudong Liu, Qihuan Xu, Wei Chen, Hong Cao, Rongjiong Zheng, Gang Li
Pages: 941-947
Published online on: 01 April 2009

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Article

Influence of basic fibroblast growth factor on the growth of HeLa cells and the expression of angiogenin

Jianli Yang, Ji Wang, Jia Zhao, Dan Zuo, Xingrong Li, Li Wang
Pages: 949-955
Published online on: 01 April 2009

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Article

Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma

Chanisa Chuaysri, Peti Thuwajit, Anucha Paupairoj, Siri Chau-In, Tuangporn Suthiphongchai, Chanitra Thuwajit
Pages: 957-969
Published online on: 01 April 2009

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Article

Assessment of human papillomavirus and Epstein-Barr virus in lung adenocarcinoma

Wan-Teck Lim, Khoon Leong Chuah, Swan Swan Leong, Eng Huat Tan, Chee Keong Toh
Pages: 971-975
Published online on: 01 April 2009

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Article

Crosstalk between adenosine receptor (A2A isoform) and ERα mediates ethanol action in MCF-7 breast cancer cells

Nicolas Etique, Isabelle Grillier-Vuissoz, Julie Lecomte, Stephane Flament
Pages: 977-981
Published online on: 01 April 2009

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Article

Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development

Yu-Mei Ding, Ji-Hua Dong, Li-Li Chen, Han-Dong Zhang
Pages: 983-987
Published online on: 01 April 2009

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Article

A pilot study of vasculogenic mimicry immunohistochemical expression in intraocular melanoma model

Luxia Chen, Shiwu Zhang, Xiaorong Li, Baocun Sun, Xiulan Zhao, Danfang Zhang, Shaozhen Zhao
Pages: 989-994
Published online on: 01 April 2009

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Article

More than 45% of A549 and H446 cells are cancer initiating cells: Evidence from cloning and tumorigenic analyses

Xiangjiao Meng, Xiuwen Wang, Yawei Wang
Pages: 995-1000
Published online on: 01 April 2009

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Article

Mutational analysis of Smad7 in human cervical cancer

Ramkumar Hariharan, Janki Mohan Babu, Rema P, M. Radhakrishna Pillai
Pages: 1001-1004
Published online on: 01 April 2009

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Article

Phase I study of combination chemotherapy with irinotecan hydrochloride and nedaplatin for cervical squamous cell carcinoma: Japanese gynecologic oncology group study

Kaichiro Yamamoto, Katsuji Kokawa, Naohiko Umesaki, Ryuichiro Nishimura, Kazuo Hasegawa, Ikuo Konishi, Fumitaka Saji, Masato Nishida, Hiroshi Noguchi, Ken Takizawa
Pages: 1005-1009
Published online on: 01 April 2009

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Article

Beta-interferon, retinoids and tamoxifen in metastatic breast cancer: Long-term follow-up of a phase II study

Francesco Recchia, Gigliola Sica, Giampiero Candeloro, Stefano Necozione, Roberta Bisegna, Massimo Bratta, Silvio Rea
Pages: 1011-1016
Published online on: 01 April 2009

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Article

Novel cell culture model for prevention of carcinogenic risk in familial adenomatous polyposis syndrome

Nitin Telang, Meena Katdare
Pages: 1017-1021
Published online on: 01 April 2009

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Article

Correlation between efficacy and skin rash occurrence following treatment with the epidermal growth factor receptor inhibitor cetuximab: A single institution retrospective analysis

Michele Orditura, Ferdinando De Vita, Gennaro Galizia, Eva Lieto, Loredana Vecchione, Fabiana Vitiello, Erika Martinelli, Fortunato Ciardiello
Pages: 1023-1028
Published online on: 01 April 2009

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Article

Bone marrow stem cell damage after three different chemotherapy regimens for advanced Hodgkin's lymphoma

Paolo G. Gobbi, Francesco Valentino, Marco Danova, Fortunato Morabito, Bianca Rovati, Caterina Mammi, Massimo Gentile, Francesco Merli, Caterina Stelitano, Stefano Luminari, Gianni Quintana, Emilio Iannitto, Maura Brugiatelli, Massimo Federico
Pages: 1029-1035
Published online on: 01 April 2009

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Article

Expression of 5-fluorouracil-related enzymes in lung cancer: ELISA characterizes enzyme activity and messenger RNA expression

Masanori Tsuchida, Yasushi Yamato, Takehisa Hashimoto, Hirohiko Shinohara, Hajime Umezu, Katsuo Yoshiya, Teruaki Koike, Jun-ichi Hayashi
Pages: 1037-1043
Published online on: 01 April 2009

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Article

Seventeen years of experience with ATRA-based therapy for acute promyelocytic leukaemia: Long-term follow-up of patients treated at S. Martino Hospital, Genoa

Marino Clavio, Anna Ghiso, Chiara Ghiggi, Mauro Spriano, Nicoletta Colombo, Raffaella Grasso, Riccardo Varaldo, Maurizio Miglino, Ivana Pierri, Francesca Olcese, Sara Aquino, Samantha Biasco, Enrico Balleari, Angelo Michele Carella, Mario Sessarego, Marco Gobbi
Pages: 1045-1052
Published online on: 01 April 2009

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Article

The role of Id-1 in chemosensitivity and epirubicin-induced apoptosis in bladder cancer cells

Hao Hu, Hui Ying Han, Yu Liang Wang, Xiao Peng Zhang, Chee Wai Chua, Y. C. Wong, Xiao Feng Wang, Ming Tat Ling, Ke Xin Xu
Pages: 1053-1059
Published online on: 01 April 2009

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Article

Clinical comparison of QOL and adverse events during postoperative adjuvant chemotherapy in outpatients with node-positive colorectal cancer or gastric cancer

Masaya Mukai, Kyoko Kishima, Fumino Uchiumi, Emi Ishibashi, Maki Fukasawa, Takayuki Tajima, Masato Nakamura, Hiroyasu Makuuchi
Pages: 1061-1066
Published online on: 01 April 2009

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Article

Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma

Shigeru Tsunoda, Eric Smith, Neville J. De Young, Xian Wang, Zi-Qing Tian, Jun-Feng Liu, Glyn G. Jamieson, Paul A. Drew
Pages: 1067-1073
Published online on: 01 April 2009

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Article

Tanshinone IIA inhibits leukemia THP-1 cell growth by induction of apoptosis

Jia-Jun Liu, Yong Zhang, Dong-Jun Lin, Ruo-Zhi Xiao
Pages: 1075-1081
Published online on: 01 April 2009

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Article

Enhanced effects of PPARγ ligands and RXR selective retinoids in combination to inhibit migration and invasiveness in cancer cells

A. Papi, P. Rocchi, A. M. Ferreri, F. Guerra, M. Orlandi
Pages: 1083-1089
Published online on: 01 April 2009

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Article

Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: Relationship to acute phase response and survival

Alastair G.W. Moses, Jean Maingay, Kathryn Sangster, Kenneth C.H. Fearon, James A. Ross
Pages: 1091-1095
Published online on: 01 April 2009

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Article

Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma

Kam-Wing Leung, Chen-Hsun Tsai, Michael Hsiao, Ching-Juinn Tseng, Luo-Ping Ger, Kuen-Haur Lee, Pei-Jung Lu
Pages: 1097-1104
Published online on: 01 April 2009

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Article

Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia

Alper Celik, Yoshihiko Kano, Shingo Tsujinaka, Sinichirou Okada, Koichi Takao, Masakazu Takagi, Shigeru Chohnan, Kuniyasu Soda, Masanobu Kawakami, Fumio Konishi
Pages: 1105-1111
Published online on: 01 April 2009

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Article

Role of CCL5 in invasion, proliferation and proportion of CD44+/CD24− phenotype of MCF-7 cells and correlation of CCL5 and CCR5 expression with breast cancer progression

Yimin Zhang, Feng Yao, Xiaoli Yao, Changhong Yi, Cheng Tan, Lei Wei, Shengrong Sun
Pages: 1113-1121
Published online on: 01 April 2009

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Article

Prognostic significance of altered expression of SDC2 and CYR61 in esophageal squamous cell carcinoma

Xin Huang, Da-Wei Xiao, Li-Yan Xu, Hai-Jun Zhong, Lian-Di Liao, Ze-Fen Xie, En-Min Li
Pages: 1123-1129
Published online on: 01 April 2009

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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