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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2010 Volume 24 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Male breast cancer: Risk factors, diagnosis, and management (Review)

Katherine A. Johansen Taber, Lee R. Morisy, Albert J. Osbahr, Barry D. Dickinson
Pages: 1115-1120
Published online on: 01 November 2010

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Article

Chemotherapy for breast cancer (Review)

M. S.U. Hassan, J. Ansari, D. Spooner, S. A. Hussain
Pages: 1121-1131
Published online on: 01 November 2010

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Article Open Access

Characterization of an alternative transcript of the human CREB3L2 gene

Ioannis Panagopoulos, Nastaran Monsef, Anna Collin, Fredrik Mertens
Pages: 1133-1139
Published online on: 01 November 2010

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Article Open Access

Schedule-dependent antitumor activity of the combination with erlotinib and docetaxel in human non-small cell lung cancer cells with EGFR mutation, KRAS mutation or both wild-type EGFR and KRAS

Koh Furugaki, Toshiki Iwai, Masatoshi Shirane, Kumiko Kondoh, Yoichiro Moriya, Kazushige Mori
Pages: 1141-1146
Published online on: 01 November 2010

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Article Open Access

Analogy between sphere forming ability and stemness of human hepatoma cells

Yusuke Uchida, Shinji Tanaka, Arihiro Aihara, Rama Adikrisna, Kenichirou Yoshitake, Satoshi Matsumura, Yusuke Mitsunori, Ayano Murakata, Norio Noguchi, Takumi Irie, Atsushi Kudo, Noriaki Nakamura, Paul B. Lai, Shigeki Arii
Pages: 1147-1151
Published online on: 01 November 2010

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Article

Scutellarin inhibits cell migration by regulating production of αvβ6 integrin and E-cadherin in human tongue cancer cells

Haixia Li, Dayong Huang, Zhongxiuzi Gao, Yanhong Lv, Lina Zhang, Haidong Cui, Jinhua Zheng
Pages: 1153-1160
Published online on: 01 November 2010

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Article

Non-surgical care for locally advanced breast cancer: Radiologically assessed therapeutic outcome of a new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II) with systemic chemotherapy

Kana Miyatake, Kei Kubota, Yasuhiro Ogawa, Norihiko Hamada, Yoriko Murata, Akihito Nishioka
Pages: 1161-1168
Published online on: 01 November 2010

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Induction of apoptosis by HAC-Y6, a novel microtubule inhibitor, through activation of the death receptor 4 signaling pathway in human hepatocellular carcinoma cells

Jui-Ying Tsai, Chao-Ming Hung, Shih-Ting Bai, Chi-Hung Huang, Wei-Chih Chen, Jinh-Gung Chung, Sheng-Chu Kuo, Tzong-Der Way, Li-Jiau Huang
Pages: 1169-1178
Published online on: 01 November 2010

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Article

Expression of urotensin II and its receptor in human lung adenocarcinoma A549 cells and the effect of urotensin II on lung adenocarcinoma growth in vitro and in vivo

Yu-Qing Wu, Zheng Song, Cheng-Hua Zhou, Shu-Hua Xing, Dong-Sheng Pei, Jun-Nian Zheng
Pages: 1179-1184
Published online on: 01 November 2010

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Discrepancy of biologic behavior influenced by bone marrow derived cells in lung cancer

Jie Zhang, Xiao-Min Niu, Mei-Lin Liao, Yun Liu, Hui-Fang Sha, Yi Zhao, Yong-Feng Yu, Qiang Tan, Jia-Qing Xiang, Jing Fang, Dan-Dan Lv, Xue-Bing Li, Shun Lu, Hai-Quan Chen
Pages: 1185-1192
Published online on: 01 November 2010

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Article

Regulation of apoptosis by p53-inducible transmembrane protein containing sushi domain

Hongyan Cui, Hiroki Kamino, Yasuyuki Nakamura, Noriaki Kitamura, Takafumi Miyamoto, Daisuke Shinogi, Olga Goda, Hirofumi Arakara, Manabu Futamura
Pages: 1193-1200
Published online on: 01 November 2010

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Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients

Shusaku Takahashi, Toshiya Kamiyama, Utano Tomaru, Akihiro Ishizu, Toshiyuki Shida, Mineji Osaka, Yutaka Sato, Yutaka Saji, Michitaka Ozaki, Satoru Todo
Pages: 1201-1212
Published online on: 01 November 2010

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Induction chemotherapy with TPF (Docetaxel, Carboplatin and Fluorouracil) in the treatment of locally advanced squamous cell carcinoma of the head and neck

J. D. Schultz, G. Bran, C. Anders, H. Sadick, A. Faber, K. Hörmann, A. Sauter
Pages: 1213-1216
Published online on: 01 November 2010

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Article

Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway

Jian Zhang, Yongping Du, Changgui Wu, Xinling Ren, Xinyu Ti, Jieran Shi, Feng Zhao, Hong Yin
Pages: 1217-1223
Published online on: 01 November 2010

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Differential expression of hedgehog signaling components and Snail/E-cadherin in human brain tumors

Chia-Hua Chou, Ann-Shung Lieu, Chia-Hung Wu, Li-Kwan Chang, Joon-Khim Loh, Run-Chin Lin, Wei-Jay Chen, Huei-De Liao, Wen-Shane Fu, Chung-Shing Chang, Ching-Chih Lin, Ching-Mei Hsu, Chung-Ching Chio, Shen-Long Howng, Yi-Ren Hong
Pages: 1225-1232
Published online on: 01 November 2010

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Article

Loss of ERα and FOXA1 expression in a progression model of luminal type breast cancer: Insights from PyMT transgenic mouse model

Kasi McCune, Rutika Mehta, Mangesh A. Thorat, Sunil Badve, Harikrishna Nakshatri
Pages: 1233-1239
Published online on: 01 November 2010

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MMP13 is a potential prognostic marker for colorectal cancer

Ming-Yii Huang, Hui-Jen Chang, Fu-Yen Chung, Ming-Je Yang, Yu-Hsiang Yang, Jaw-Yuan Wang, Shiu-Ru Lin
Pages: 1241-1247
Published online on: 01 November 2010

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Article

Induction of a less aggressive phenotype in human colon carcinoma HCT116 cells by chronic exposure to HDAC inhibitor SAHA

Alessandro Bressan, Mario Bigioni, Daniela Bellarosa, Federica Nardelli, Clelia Irrissuto, Carlo Alberto Maggi, Monica Binaschi
Pages: 1249-1255
Published online on: 01 November 2010

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The distribution and expression profiles of human Aspartyl/Asparaginyl beta-hydroxylase in tumor cell lines and human tissues

Hui Yang, Kai Song, Tian Xue, Xiao-Ping Xue, Ting Huyan, Wei Wang, Hua Wang
Pages: 1257-1264
Published online on: 01 November 2010

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Article

Overexpression of BDNF and TrkB in human bladder cancer specimens

Pei Chun Lai, Ted H. Chiu, Yen Ta Huang
Pages: 1265-1270
Published online on: 01 November 2010

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Article

Diagnostic value of serum haptoglobin protein as hepatocellular carcinoma candidate marker complementary to α fetoprotein

Hong Shu, Xiaonan Kang, Kun Guo, Shan Li, Mei Li, Lu Sun, Lin Gan, Yinkun Liu, Xue Qin
Pages: 1271-1276
Published online on: 01 November 2010

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Article

A cluster of inflammatory breast cancer (IBC) in an office setting: Additional evidence of the importance of environmental factors in IBC etiology

Tina J. Duke, Nasreen C. Jahed, Carmela C. Veneroso, Ricardo Da Roza, Owen Johnson, Daniel Hoffman, Sanford H. Barsky, Paul H. Levine
Pages: 1277-1284
Published online on: 01 November 2010

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Article

Oncolytic adenovirus mediated Survivin RNA interference and 5-fluorouracil synergistically suppress the lymphatic metastasis of colorectal cancer

Wei Shen, Jing-Kai Tu, Xue-Hu Wang, Zhong-Xue Fu
Pages: 1285-1290
Published online on: 01 November 2010

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Article

erbB2 gene silencing and its effect on PTEN in SACC-83 salivary adenoid cystic carcinoma cells

Xiaohua Liu, Yincheng Zhang, Wenhao Ren, Guozhou Rao
Pages: 1291-1296
Published online on: 01 November 2010

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Article

Replication-dependent γ-H2AX formation is involved in docetaxel-induced apoptosis in NSCLC A549 cells

Feng Zhang, Tao Zhang, Yang Qu, Tao Jiang, Yun-Xin Cao, Chen Li, Lei Fan, Qi-Bing Mei
Pages: 1297-1305
Published online on: 01 November 2010

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Article

Gimeracil, a component of S-1, may enhance the antitumor activity of X-ray irradiation in human cancer xenograft models in vivo

Masakazu Fukushima, Kazuki Sakamoto, Minoru Sakata, Fumio Nakagawa, Hitoshi Saito, Yu Sakata
Pages: 1307-1313
Published online on: 01 November 2010

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Article

Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells

Joanna C. Pointon, Gina Eagle, James Bailey, Paul Evans, David Allsup, John Greenman
Pages: 1315-1321
Published online on: 01 November 2010

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Article

Vaccination of full-length HPV16 E6 or E7 protein inhibits the growth of HPV16 associated tumors

Yan-Li Li, Xu-Hua Qiu, Chen Shen, Jian-Ning Liu, Jing Zhang
Pages: 1323-1329
Published online on: 01 November 2010

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Article

Estrogen receptor β and epidermal growth factor receptor as early-stage prognostic biomarkers of non-small cell lung cancer

Laura Valeria Mauro, Mercedes Dalurzo, María José Carlini, David Smith, Myriam Nuñez, Marina Simian, José Lastiri, Bartolomé Vasallo, Elisa Bal de Kier Joffé, María Guadalupe Pallotta, Lydia Puricelli
Pages: 1331-1338
Published online on: 01 November 2010

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Article

Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell line growth

Eduardo Parra, Jorge Ferreira
Pages: 1339-1345
Published online on: 01 November 2010

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Article

Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population

Ivona Hlavata, David Vrana, Zdenek Smerhovsky, Barbara Pardini, Alessio Naccarati, Pavel Vodicka, Jan Novotny, Beatrice Mohelnikova-Duchonova, Pavel Soucek
Pages: 1347-1353
Published online on: 01 November 2010

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Article

Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines

Paula Schiapparelli, Mónica Enguita-Germán, Jana Balbuena, Juan A. Rey, Paula Lázcoz, Javier S. Castresana
Pages: 1355-1362
Published online on: 01 November 2010

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Article

microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2

Hao Zhang, Xiaobing Cai, Yang Wang, Hao Tang, Daki Tong, Fang Ji
Pages: 1363-1369
Published online on: 01 November 2010

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Article

A subset of microRNAs potentially acts as a convergent hub for upstream transcription factors in cancer cells

Hiroaki Ohdaira, Tomoe Sasaki, Kenichi Yoshida
Pages: 1371-1381
Published online on: 01 November 2010

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Article

The impact of conventional or hypofractionated radiotherapy on voice quality and oncological outcome in patients with early glottic cancer

L. Di Nicola, G. L. Gravina, F. Marampon, P. Bonfili, S. Buonopane, M. Di Staso, C. Festuccia, P. Franzese, M. Tombolini, V. Tombolini
Pages: 1383-1388
Published online on: 01 November 2010

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Article

Cooperation of actin-sequestering protein, thymosin β-4 and hypoxia inducible factor-1α in tumor cell migration

Yun-Kyoung Ryu, Yun-Sun Im, Eun-Yi Moon
Pages: 1389-1394
Published online on: 01 November 2010

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Article

The antiandrogen bicalutamide activates the androgen receptor (AR) with a mutation in codon 741 through the mitogen activated protein kinase (MARK) pathway in human prostate cancer PC3 cells

Tomoaki Terakawa, Hideaki Miyake, Masafumi Kumano, Iori Sakai, Masato Fujisawa
Pages: 1395-1399
Published online on: 01 November 2010

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Article

Suppressed protein expression of the death-associated protein kinase enhances 5-fluorouracil-sensitivity but not etoposide-sensitivity in human endometrial adenocarcinoma cells

Tetsuji Tanaka, Tao Bai, Kazunori Yukawa
Pages: 1401-1405
Published online on: 01 November 2010

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

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Published online on: 04 June 2026

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Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

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Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

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Article Number: 140
Published online on: 29 May 2026

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