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2010 Impact Factor: 1.686
Journal Citation Reports®
Thomson 2011

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Early Online Publication

Spandidos Publication’s Early Online feature allows for the publication of articles online before they appear in print. The Early Online articles are listed below in order of publication date. The online publication date appears below each title, followed by the article’s unique Digital Object Identifier (DOI).
Learn more about Early Online articles.

Epithelial mesenchymal transition correlates with CD24+CD44+ and CD133+ cells in pancreatic cancer
Ye Zhang, Jishu Wei, Hui Wang, Xiaofeng Xu, Yong An, Dong Tang, Zhongxu Yuan, Feitong Wang, Junli Wu, Jingjing Zhang, Yi Miao
Published online on: Tuesday, February 7, 2012 Doi: 10.3892/or.2012.1681

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Whole blood RNA expression profiles in ovarian cancer patients with or without residual tumors after primary cytoreductive surgery
Helena S. Isaksson, Bengt Sorbe, Torbjörn K. Nilsson
Published online on: Tuesday, February 7, 2012 Doi: 10.3892/or.2012.1680
Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy
Charles C.L. Tong, K. H. Vincent Lau, Michael Rivera, David Cannan, Julio Aguirre-Ghiso, Andrew G. Sikora, Vishal Gupta, Kevin Forsythe, Eric C. Ko, Krzysztof Misiukiewicz, Vivek Gurudutt, Marita S. Teng, Stuart H. Packer, Eric M. Genden, Johnny Kao
Published online on: Tuesday, February 7, 2012 Doi: 10.3892/or.2012.1679
Characteristic CYP2A6 genetic polymorphisms detected by TA cloning-based sequencing in Chinese digestive system cancer patients with S-1 based chemotherapy
Wei-Jia Fang, Hai-Bo Mou, Da-Zhi Jin, Yu-Long Zheng, Peng Zhao, Chen-Yu Mao, Ling Peng, Ming-Zhu Huang, Nong Xu
Published online on: Tuesday, February 7, 2012 Doi: 10.3892/or.2012.1678

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Crotoxin enhances the antitumor activity of gefinitib (Iressa) in SK-MES-1 human lung squamous carcinoma cells
Jun-Hua Wang, Yan Xie, Jun-Chao Wu, Rong Han, Paul F. Reid, Zheng-Hong Qin, Jing-Kang He
Published online on: Monday, February 6, 2012 Doi: 10.3892/or.2012.1677
CRTC1-MAML2 gene fusion in mucoepidermoid carcinoma of the lacrimal gland
Sarah Linéa Von Holstein, André Fehr, Steffen Heegaard, Marianne Hamilton Therkildsen, Göran Stenman
Published online on: Monday, February 6, 2012 Doi: 10.3892/or.2012.1676
Molecular targeted therapies for cancer: Sorafenib mono­therapy and its combination with other therapies (Review)
Nuha Ibrahim, Yan Yu, William R. Walsh, Jia-Lin Yang
Published online on: Monday, February 6, 2012 Doi: 10.3892/or.2012.1675

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CXCL12 mediates apoptosis resistance in rat C6 glioma cells
Kirsten Hattermann, Rolf Mentlein, Janka Held-Feindt
Published online on: Monday, February 6, 2012 Doi: 10.3892/or.2012.1674
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers
Ronald A. Lubet, Margie L. Clapper, David L. McCormick, Michael A. Pereira, W-C. L. Chang, Vernon E. Steele, Susan M. Fischer, M. Margaret Juliana, Clinton J. Grubbs
Published online on: Friday, February 3, 2012 Doi: 10.3892/or.2012.1673
Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines
Xue-Feng Huang, Jie Han, Xiao-Tong Hu, Chao He
Published online on: Friday, February 3, 2012 Doi: 10.3892/or.2012.1672
Mitochondrial localization of P-glycoprotein in the human breast cancer cell line MCF-7/ADM and its functional characterization
Yi Shen, Yan Chu, Yan Yang, Zehua Wang
Published online on: Thursday, February 2, 2012 Doi: 10.3892/or.2012.1671
Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells
Xiaomei Wu, Qin Yan, Zhenbo Zhang, Guiqiang Du, Xiaoping Wan
Published online on: Thursday, February 2, 2012 Doi: 10.3892/or.2012.1670
NF-κB activity is downregulated by KRAS knockdown in SW620 cells via the RAS-ERK-IκBα pathway
Gen Lin, Zhiwei Tang, Yun-Bin Ye, Qiang Chen
Published online on: Thursday, February 2, 2012 Doi: 10.3892/or.2012.1669

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The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer
Haiping Chang, Jingzhi Wang, Yuan Tian, Jie Xu, Xiaojuan Gou, Jianxin Cheng
Published online on: Wednesday, February 1, 2012 Doi: 10.3892/or.2012.1668

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Novel identification of the ETS-1 splice variants p42 and p27 in prostate cancer cell lines
Zaki Shaikhibrahim, Jacqueline Ochsenfahrt, Kerstin Fuchs, Nicolas Wernert
Published online on: Wednesday, February 1, 2012 Doi: 10.3892/or.2012.1667
Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer
Helena J. Mauceri, Harold G. Sutton, Thomas E. Darga, Masha Kocherginsky, Joel Kochanski, Ralph R. Weichselbaum, Everett E. Vokes
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1666
Antitumor effects of oncolytic adenovirus armed with Drosophila melanogaster deoxyribonucleoside kinase in colorectal cancer
Shuai Ma, Wenzhi Qu, Liang Mao, Zhi Zhu, Lanling Jia, Lei Zhao, Xinyu Zheng
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1665
P21-activated protein kinase 1 is overexpressed in gastric cancer and induces cancer metastasis
Liang-Hui Li, Qi Luo, Min-Hua Zheng, Chao Pan, Guo-Yang Wu, Yi-Zhuo Lu, Bo Feng, Xue-Hua Chen, Bing-Ya Liu
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1664
Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells
Lihua Liu, Jun Meng, Cong Zhang, Yuqing Duan, Lianmei Zhao, Shijie Wang, Baoen Shan
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1663
3,3'-Diindolylmethane suppresses growth of human esophageal squamous cancer cells by G1 cell cycle arrest
Seo Ju Kim, Ju-Seog Lee, Soo Mi Kim
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1662
MAPK inhibitors and siRNAs differentially affect cell death and ROS levels in arsenic trioxide-treated human pulmonary fibroblast cells
Woo Hyun Park
Published online on: Friday, January 27, 2012 Doi: 10.3892/or.2012.1661
Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients
Hiromichi Matsuoka, Tokuzo Arao, Chihiro Makimura, Masayuki Takeda, Hidemi Kiyota, Junji Tsurutani, Yoshihiko Fujita, Kazuko Matsumoto, Hideharu Kimura, Masatomo Otsuka, Atsuko Koyama, Chiyo K. Imamura, Yusuke Tanigawara, Takeharu Yamanaka, Kyoko Tanaka, Kazuto Nishio, Kazuhiko Nakagawa
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1660
Lapatinib, a dual inhibitor of EGFR and HER2, has synergistic effects with 5-fluorouracil on esophageal carcinoma
Xiao-Fang Guo, Xiao-Fei Zhu, Gen-Shen Zhong, Bao-Guo Deng, Zhi-Tao Gao, Hui Wang
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1659
Differential staining of γ synuclein in poorly differentiated compared to highly differentiated colon cancer cells
Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1658
Pre-neoplastic lesion, mucin-depleted foci, reveals de novo high-grade dysplasia in rat colon carcinogenesis
Changxu Cui, Reika Takamatsu, Hiroshi Doguchi, Akiko Matsuzaki, Masanao Saio, Naoki Yoshimi
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1657
Chlorophyllin e4 is a novel photosensitizer against human bladder cancer cells
Bin Li, Zhiming Wu, Wenzhi Li, Guojin Jia, Jiancheng Lu, Jie Fang, Gang Chen
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1656
Effect of inhibition of the adrenomedullin gene on the growth and chemosensitivity of ovarian cancer cells
Pan Chen, Xiaoyan Pang, Yi Zhang, Yunqin He
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1655
Increased basic fibroblast growth factor release and proliferation in xenotransplanted squamous cell carcinoma after combined irradiation/anti-vascular endothelial growth factor treatment
Kai Fruth, Stefan Weber, Yunus Okcu, Ruediger Noppens, Klaus U. Klein, Eva Joest, Jana Hedrich, Sebastian Thilemann, Benjamin Pogorzelski, Dimitrios Koutsimpelas, Stefan Fischer, Kerstin Muennemann, Annette Affolter, Ulf R. Heinrich, Christoph Brochhausen, Irene Schmidtmann, Wolf J. Mann, Heinz Schmidberger, Laura M. Schreiber, Juergen Brieger
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1654
Novel mutations of the HRAS gene and absence of hotspot mutations of the BRAF genes in oral squamous cell carcinoma in a Greek population
Dimitra Koumaki, George Kostakis, Vasiliki Koumaki, Nikolaos Papadogeorgakis, Michael Makris, Alexandros Katoulis, Smaragda Kamakari, George Koutsodontis, Christos Perisanidis, Vaia Lambadiari, Evanthia Chrysomali, Nikolaos Stavrianeas, Constantinos Alexandridis, Dimitrios Rigopoulos
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1653
miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells
Jianwei Hao, Chunzhi Zhang, Anlin Zhang, Kun Wang, Zhifan Jia, Guangxiu Wang, Lei Han, Chunsheng Kang, Peiyu Pu
Published online on: Thursday, January 26, 2012 Doi: 10.3892/or.2012.1652
Chemoembolization of unresectable hepatocellular carcinoma: Decreased toxicity with slow-release doxorubicin‑eluting beads compared with lipiodol
Francesco Recchia, Giovanni Passalacqua, Pietro Filauri, Marco Doddi, Pietro Boscarato, Giampiero Candeloro, Stefano Necozione, Giovambattista Desideri, Silvio Rea
Published online on: Wednesday, January 25, 2012 Doi: 10.3892/or.2012.1651
Prognostic significance of PDCD4 expression and association with microRNA-21 in each Dukes' stage of colorectal cancer patients
Atsushi Horiuchi, Hisae Iinuma, Takuya Akahane, Ryu Shimada, Toshiaki Watanabe
Published online on: Thursday, January 19, 2012 Doi: 10.3892/or.2012.1648
Cinobufocini inhibits NF-κB and COX-2 activation induced by TNF-α in lung adenocarcinoma cells
Ju-Yong Wang, Ling Chen, Zhan Zheng, Qing Wang, Jing Guo, Ling Xu
Published online on: Thursday, January 19, 2012 Doi: 10.3892/or.2012.1647
Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells
Moo Rim Kang, Song-Kyu Park, Chang Woo Lee, Ig Jun Cho, Yeong Nang Jo, Jeong Wook Yang, Jin-Ah Kim, Jieun Yun, Ki Hoon Lee, Hyun Ju Kwon, Byung Woo Kim, Kiho Lee, Jong Soon Kang, Hwan Mook Kim
Published online on: Thursday, January 19, 2012 Doi: 10.3892/or.2012.1644
Plasmid DNA introduced into cultured cells with diagnostic ultrasound
Minoru Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida
Published online on: Thursday, January 19, 2012 Doi: 10.3892/or.2012.1643

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Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer
Yoshifumi Nakayama, Masumi Yamauchi, Noritaka Minagawa, Takayuki Torigoe, Hiroto Izumi, Kimitoshi Kohno, Koji Yamaguchi
Published online on: Monday, January 16, 2012 Doi: 10.3892/or.2012.1640
Lycii cortex radicis extract inhibits glioma tumor growth in vitro and in vivo through downregulation of the Akt/ERK pathway
Ji Cheon Jeong, Saeng Jae Kim, Yong Keun Kim, Chae Hwa Kwon, Ki Hyung Kim
Published online on: Monday, January 16, 2012 Doi: 10.3892/or.2012.1637
Natural history of human aberrant crypt foci and correlation with risk factors for colorectal cancer
Hidenori Ohkubo, Hirokazu Takahashi, Eiji Yamada, Eiji Sakai, Takuma Higurashi, Takashi Uchiyama, Kunihiro Hosono, Hiroki Endo, Masataka Taguri, Atsushi Nakajima
Published online on: Thursday, January 12, 2012 Doi: 10.3892/or.2012.1631
RACK1 downregulation suppresses migration and proliferation of neuroblastoma cell lines
Fan Lu, Chi Zhang, Wen-Jie Wu, Ye-Ming Wu
Published online on: Wednesday, January 11, 2012 Doi: 10.3892/or.2012.1629

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Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations
Naoto Sato, Yasushi Saga, Hiroaki Mizukami, Dongdong Wang, Hiroyuki Fujiwara, Yuji Takei, Shizuo Machida, Keiya Ozawa, Mitsuaki Suzuki
Published online on: Wednesday, January 11, 2012 Doi: 10.3892/or.2012.1626
Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1-RAGE and Akt pathways in vitro and in vivo
Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen
Published online on: Monday, January 9, 2012 Doi: 10.3892/or.2012.1623
Association of aberrant DNA methylation with clinicopathological features in breast cancer
Aggeliki Tserga, Nicolaos V. Michalopoulos, Georgia Levidou, Penelope Korkolopoulou, George Zografos, Efstratios Patsouris, Angelica A. Saetta
Published online on: Monday, December 5, 2011 Doi: 10.3892/or.2011.1576
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