Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis

  • Authors:
    • Gang Wang
    • Yifen Wu
    • Zhentao Zhang
    • Xiaolin Zheng
    • Yulan Zhang
    • Manqiu Liang
    • Huanchu Yuan
    • Haiping Shen
    • Dewei Li
  • View Affiliations

  • Published online on: March 11, 2016     https://doi.org/10.3892/etm.2016.3150
  • Pages: 1937-1942
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Abstract

The aim of the present study was to investigate the effect of heart rate (HR) on the diagnostic accuracy of 256-slice computed tomography angiography (CTA) in the detection of coronary artery stenosis. Coronary imaging was performed using a Philips 256-slice spiral CT, and receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic value of 256‑slice CTA in coronary artery stenosis. The HR of the research subjects in the study was within a certain range (39‑107 bpm). One hundred patients suspected of coronary heart disease underwent 256-slice CTA examination. The cases were divided into three groups: Low HR (HR <75 bpm), moderate HR (75≤ HR <90 bpm) and high HR (HR ≥90 bpm). For the three groups, two observers independently assessed the image quality for all coronary segments on a four‑point ordinal scale. An image quality of grades 1‑3 was considered diagnostic, while grade 4 was non‑diagnostic. A total of 97.76% of the images were diagnostic in the low‑HR group, 96.86% in the moderate‑HR group and 95.80% in the high‑HR group. According to the ROC curve analysis, the specificity of CTA in diagnosing coronary artery stenosis was 98.40, 96.00 and 97.60% in the low‑, moderate‑ and high‑HR groups, respectively. In conclusion, 256‑slice coronary CTA can be used to clearly show the main segments of the coronary artery and to effectively diagnose coronary artery stenosis. Within the range of HRs investigated, HR was found to have no significant effect on the diagnostic accuracy of 256-slice coronary CTA for coronary artery stenosis.
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May-2016
Volume 11 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Wang G, Wu Y, Zhang Z, Zheng X, Zhang Y, Liang M, Yuan H, Shen H and Li D: Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis. Exp Ther Med 11: 1937-1942, 2016.
APA
Wang, G., Wu, Y., Zhang, Z., Zheng, X., Zhang, Y., Liang, M. ... Li, D. (2016). Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis. Experimental and Therapeutic Medicine, 11, 1937-1942. https://doi.org/10.3892/etm.2016.3150
MLA
Wang, G., Wu, Y., Zhang, Z., Zheng, X., Zhang, Y., Liang, M., Yuan, H., Shen, H., Li, D."Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis". Experimental and Therapeutic Medicine 11.5 (2016): 1937-1942.
Chicago
Wang, G., Wu, Y., Zhang, Z., Zheng, X., Zhang, Y., Liang, M., Yuan, H., Shen, H., Li, D."Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1937-1942. https://doi.org/10.3892/etm.2016.3150