COMBINED POSTOPERATIVE RADIOTHERAPY AND PCV-CHEMOTHERAPY (CCNU, PROCARBAZINE AND VINCRISTINE) IN MANAGING ANAPLASTIC ASTROCYTOMA - A REPORT OF A LONG-TERM FOLLOW-UP
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- Published online on: June 1, 1993 https://doi.org/10.3892/ijo.2.6.1063
- Pages: 1063-1066
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Abstract
Postoperative radiotherapy together with CCNU, procarbazine and vincristine (PCV-chemotherapy regimen) were analysed in patients with histologically confirmed anaplastic astrocytoma. This report evaluates the long-term survival correlated with important prognostic variables. Patients who received more than 6 courses of the PCV-chemotherapy had significantly longer survival (P=0.03). Age and performance status, identified as important prognostic factors in previous studies, are confirmed in this analysis.